메뉴 건너뛰기




Volumn 83, Issue 11, 2007, Pages 1477-1484

Intragraft FOXP3 mRNA expression reflects antidonor immune reactivity in cardiac allograft patients

Author keywords

Cardiac allograft patients; Endomyocardial biopsies; FOXP3; Gene expression levels

Indexed keywords

CELL MARKER; CYCLOSPORIN A; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GANCICLOVIR; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GRANZYME B; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY; TRANSCRIPTION FACTOR FOXP3;

EID: 34250617034     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000264997.53153.8b     Document Type: Article
Times cited : (50)

References (35)
  • 1
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995; 155: 1151.
    • (1995) J Immunol , vol.155 , pp. 1151
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3
  • 2
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4: 330.
    • (2003) Nat Immunol , vol.4 , pp. 330
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 3
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004; 22: 531.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531
    • Sakaguchi, S.1
  • 4
    • 1242290580 scopus 로고    scopus 로고
    • Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: The role of IL-2, TGF-beta, and IL-10
    • Zheng SG, Wang JH, Gray JD, et al. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: The role of IL-2, TGF-beta, and IL-10. J Immunol 2004; 172: 5213.
    • (2004) J Immunol , vol.172 , pp. 5213
    • Zheng, S.G.1    Wang, J.H.2    Gray, J.D.3
  • 5
    • 1242295283 scopus 로고    scopus 로고
    • Regulatory T cells and organ transplantation
    • Waldmann H, Graca L, Cobbold S, et al. Regulatory T cells and organ transplantation. Semin Immunol 2004; 16: 119.
    • (2004) Semin Immunol , vol.16 , pp. 119
    • Waldmann, H.1    Graca, L.2    Cobbold, S.3
  • 6
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings MK, Bacchetta R, Schulz U, Roncarolo MG. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 2002; 129: 263.
    • (2002) Int Arch Allergy Immunol , vol.129 , pp. 263
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 7
    • 0036467522 scopus 로고    scopus 로고
    • CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
    • Kingsley CI, Karim M, Bushell AR, Wood KJ. CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J Immunol 2002; 168: 1080.
    • (2002) J Immunol , vol.168 , pp. 1080
    • Kingsley, C.I.1    Karim, M.2    Bushell, A.R.3    Wood, K.J.4
  • 8
    • 0036195161 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh RS, Whitters MJ, Piccirillo CA, et al. CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 2002; 16: 311.
    • (2002) Immunity , vol.16 , pp. 311
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3
  • 9
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057.
    • (2003) Science , vol.299 , pp. 1057
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 10
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
    • Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 2005; 102: 5138.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5138
    • Bettelli, E.1    Dastrange, M.2    Oukka, M.3
  • 11
    • 8344275995 scopus 로고    scopus 로고
    • Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
    • Yagi H, Nomura T, Nakamura K, et al. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol 2004; 16: 1643.
    • (2004) Int Immunol , vol.16 , pp. 1643
    • Yagi, H.1    Nomura, T.2    Nakamura, K.3
  • 12
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J, et al. Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001; 182: 18.
    • (2001) Immunol Rev , vol.182 , pp. 18
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 13
    • 0035806276 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
    • Taylor PA, Noelle RJ, Blazar BR. CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med 2001; 193: 1311.
    • (2001) J Exp Med , vol.193 , pp. 1311
    • Taylor, P.A.1    Noelle, R.J.2    Blazar, B.R.3
  • 14
    • 4344653864 scopus 로고    scopus 로고
    • Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells
    • Nishimura E, Sakihama T, Setoguchi R, et al. Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells. Int Immunol 2004; 16: 1189.
    • (2004) Int Immunol , vol.16 , pp. 1189
    • Nishimura, E.1    Sakihama, T.2    Setoguchi, R.3
  • 15
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca L, Cobbold SP, Waldmann H. Identification of regulatory T cells in tolerated allografts. J Exp Med 2002; 195: 1641.
    • (2002) J Exp Med , vol.195 , pp. 1641
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 16
    • 2442425262 scopus 로고    scopus 로고
    • Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants
    • Cobbold SP, Castejon R, Adams E, et al. Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J Immunol 2004; 172: 6003.
    • (2004) J Immunol , vol.172 , pp. 6003
    • Cobbold, S.P.1    Castejon, R.2    Adams, E.3
  • 17
    • 17144393320 scopus 로고    scopus 로고
    • Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
    • Lee I, Wang L, Wells AD, et al. Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J Exp Med 2005; 201: 1037.
    • (2005) J Exp Med , vol.201 , pp. 1037
    • Lee, I.1    Wang, L.2    Wells, A.D.3
  • 18
    • 33747889822 scopus 로고    scopus 로고
    • Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients
    • Segundo DS, Ruiz JC, Izquierdo M, et al. Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients. Transplantation 2006; 82: 550.
    • (2006) Transplantation , vol.82 , pp. 550
    • Segundo, D.S.1    Ruiz, J.C.2    Izquierdo, M.3
  • 19
    • 22144475453 scopus 로고    scopus 로고
    • Differential Effect of Calcineurin Inhibitors, Anti-CD25 Antibodies and Rapamycin on the Induction of FOXP3 in human T cells
    • Baan CC, van der Mast BJ, Klepper M, et al. Differential Effect of Calcineurin Inhibitors, Anti-CD25 Antibodies and Rapamycin on the Induction of FOXP3 in human T cells. Transplantation 2005; 80: 110.
    • (2005) Transplantation , vol.80 , pp. 110
    • Baan, C.C.1    van der Mast, B.J.2    Klepper, M.3
  • 20
    • 0025642851 scopus 로고
    • A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group. The International Society for Heart Transplantation
    • Billingham ME, Cary NR, Hammond ME, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group. The International Society for Heart Transplantation. J Heart Transplant 1990; 9: 587.
    • (1990) J Heart Transplant , vol.9 , pp. 587
    • Billingham, M.E.1    Cary, N.R.2    Hammond, M.E.3
  • 21
    • 22144434185 scopus 로고    scopus 로고
    • Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection
    • Stewart S, Winters GL, Fishbein MC, et al. Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection. J Heart Lung Transplant 2005; 24: 1710.
    • (2005) J Heart Lung Transplant , vol.24 , pp. 1710
    • Stewart, S.1    Winters, G.L.2    Fishbein, M.C.3
  • 22
    • 33750979838 scopus 로고    scopus 로고
    • CD25+CD4+regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection
    • Steger U, Kingsley CI, Karim M, et al. CD25+CD4+regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection. Transplantation 2006; 82: 1202.
    • (2006) Transplantation , vol.82 , pp. 1202
    • Steger, U.1    Kingsley, C.I.2    Karim, M.3
  • 23
    • 33644844341 scopus 로고    scopus 로고
    • Molecular mechanisms underlying FOXP3 induction in human T cells
    • Mantel PY, Ouaked N, Ruckert B, et al. Molecular mechanisms underlying FOXP3 induction in human T cells. J Immunol 2006; 176: 3593.
    • (2006) J Immunol , vol.176 , pp. 3593
    • Mantel, P.Y.1    Ouaked, N.2    Ruckert, B.3
  • 24
    • 33746228122 scopus 로고    scopus 로고
    • FOXP3 controls regulatory T cell function through cooperation with NFAT
    • Wu Y, Borde M, Heissmeyer V, et al. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 2006; 126: 375.
    • (2006) Cell , vol.126 , pp. 375
    • Wu, Y.1    Borde, M.2    Heissmeyer, V.3
  • 25
    • 0023907493 scopus 로고
    • Interleukin-2: Inception, impact, and implications
    • Smith KA. Interleukin-2: inception, impact, and implications. Science 1988; 240: 1169.
    • (1988) Science , vol.240 , pp. 1169
    • Smith, K.A.1
  • 26
    • 0036213755 scopus 로고    scopus 로고
    • Intragraft interleukin 2 mRNA expression during acute cellular rejection and left ventricular total wall thickness after heart transplantation
    • de Groot-Kruseman HA, Baan CC, Hagman EM, et al. Intragraft interleukin 2 mRNA expression during acute cellular rejection and left ventricular total wall thickness after heart transplantation. Heart 2002; 87: 363.
    • (2002) Heart , vol.87 , pp. 363
    • de Groot-Kruseman, H.A.1    Baan, C.C.2    Hagman, E.M.3
  • 27
    • 2442637772 scopus 로고    scopus 로고
    • Thornton AM, Donovan EE, Piccirillo CA, Shevach EM. Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+T cell suppressor function. J Immunol 2004; 172: 6519.
    • Thornton AM, Donovan EE, Piccirillo CA, Shevach EM. Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+T cell suppressor function. J Immunol 2004; 172: 6519.
  • 28
    • 33646007658 scopus 로고    scopus 로고
    • Interleukin-2-dependent mechanisms of tolerance and immunity in vivo
    • Antony PA, Paulos CM, Ahmadzadeh M, et al. Interleukin-2-dependent mechanisms of tolerance and immunity in vivo. J Immunol 2006; 176: 5255.
    • (2006) J Immunol , vol.176 , pp. 5255
    • Antony, P.A.1    Paulos, C.M.2    Ahmadzadeh, M.3
  • 29
    • 33747801470 scopus 로고    scopus 로고
    • IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
    • Zorn E, Nelson EA, Mohseni M, et al. IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo. Blood 2006; 108: 1571.
    • (2006) Blood , vol.108 , pp. 1571
    • Zorn, E.1    Nelson, E.A.2    Mohseni, M.3
  • 30
    • 1542619331 scopus 로고    scopus 로고
    • Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo
    • Martin B, Banz A, Bienvenu B, et al. Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo. J Immunol 2004; 172: 3391.
    • (2004) J Immunol , vol.172 , pp. 3391
    • Martin, B.1    Banz, A.2    Bienvenu, B.3
  • 31
    • 33745978399 scopus 로고    scopus 로고
    • Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation
    • Mempel TR, Pittet MJ, Khazaie K, et al. Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity 2006; 25: 129.
    • (2006) Immunity , vol.25 , pp. 129
    • Mempel, T.R.1    Pittet, M.J.2    Khazaie, K.3
  • 32
    • 28244444532 scopus 로고    scopus 로고
    • Messenger RNA for FOXP3 in the urine of renal-allograft recipients
    • Muthukumar T, Dadhania D, Ding R, et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med 2005; 353: 2342.
    • (2005) N Engl J Med , vol.353 , pp. 2342
    • Muthukumar, T.1    Dadhania, D.2    Ding, R.3
  • 33
    • 19944369378 scopus 로고    scopus 로고
    • Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans
    • Morgan ME, van Bilsen JH, Bakker AM, et al. Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans. Hum Immunol 2005; 66: 13.
    • (2005) Hum Immunol , vol.66 , pp. 13
    • Morgan, M.E.1    van Bilsen, J.H.2    Bakker, A.M.3
  • 34
    • 33646240855 scopus 로고    scopus 로고
    • Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
    • Gavin MA, Torgerson TR, Houston E, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA 2006; 103: 6659.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6659
    • Gavin, M.A.1    Torgerson, T.R.2    Houston, E.3
  • 35
    • 33845437519 scopus 로고    scopus 로고
    • FoxP3+ T Cells Can Be Expanded From Rejecting Cardiac Allografts
    • Dijke E, Velthuis J, Balk A, et al. FoxP3+ T Cells Can Be Expanded From Rejecting Cardiac Allografts. Transplant Proc 2006; 38: 3233.
    • (2006) Transplant Proc , vol.38 , pp. 3233
    • Dijke, E.1    Velthuis, J.2    Balk, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.