Novel tetravalent and bispecific IgG-like antibody molecules combining single-chain diabodies with the immunoglobulin γ1 Fc or CH3 region

FEBS Letters

Volumn 454, Issue 1-2, 1999, Pages 90-94

  Alt, Margitta ^a   Müller, Rolf ^a   Kontermann, Roland E ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Bispecific antibody; Dimerization; Functional affinity; Immunoglobulin constant domain; Single chain diabody

Indexed keywords

BACTERIAL ENZYME; BETA GALACTOSIDASE; BISPECIFIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN G;

ANTIBODY COMBINING SITE; ARTICLE; BINDING AFFINITY; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DIMERIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MAMMAL CELL; MODEL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANTIBODIES, BISPECIFIC; ANTIBODY AFFINITY; CELL LINE; CHROMATOGRAPHY, GEL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULINS; MODELS, BIOLOGICAL;

ESCHERICHIA COLI; MAMMALIA;

EID: 0344654890     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00782-6     Document Type: Article

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