S-nitrosoglutathione-containing hydrogel accelerates rat cutaneous wound repair

Journal of the European Academy of Dermatology and Venereology

Volumn 21, Issue 5, 2007, Pages 629-637

  Amadeu, T P ^a   Seabra, A B ^b   de Oliveira, M G ^b   Costa, A M A ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Collagen; Mast cells; Nitric oxide; Skin; Vessels; Wound healing

Indexed keywords

COLLAGEN FIBER; FORMALDEHYDE; PARAFFIN; S NITROSOGLUTATHIONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPITHELIZATION; GRANULATION TISSUE; HISTOPATHOLOGY; HYDROGEL; INFLAMMATORY CELL; MALE; MAST CELL; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN BLOOD FLOW; SKIN INFLAMMATION; SKIN INJURY; STATISTICAL SIGNIFICANCE; TISSUE FIXATION; WOUND CLOSURE; WOUND CONTRACTION; WOUND HEALING;

ADMINISTRATION, TOPICAL; ANIMALS; GRANULATION TISSUE; HYDROGEL; MALE; RATS; RATS, WISTAR; S-NITROSOGLUTATHIONE; STATISTICS, NONPARAMETRIC; WOUND HEALING;

EID: 34250334612     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2006.02032.x     Document Type: Article

References (53)

1. Witte MB, Barbul A. General principles of wound healing. Surg Clin North Am 1997; 77: 509-528.
2. Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med 1999; 341: 738-746.
3. Witte MB, Kiyama T, Barbul A. Nitric oxide enhances experimental wound healing in diabetes. Br J Surg 2002; 89: 1594-1601.
4. Knowles RG, Moncada S. Nitric-oxide synthases in mammals. Biochem J 1994; 298: 249-258.
5. Krumenacker JS, Hanafy KA, Murad F. Regulation of nitric oxide and soluble guanylyl cyclase. Brain Res Bull 2004; 62: 505-515.
6. Bruch-Gerharz D, Ruzicka T, Kolb-Bachofen V. Nitric oxide in human skin: current status and future prospects. J Invest Dermatol 1998; 110: 1-7.
7. Rizk M, Witte MB, Barbul A. Nitric oxide and wound healing. World J Surg 2004; 28: 301-306.
8. Achuth HN, Moochhala SM, Mahendran R, Tan WT. Nitrosoglutathione triggers collagen deposition in cutaneous wound repair. Wound Repair Regen 2005; 13: 383-389.
9. Burgaud JL, Riffaud JP, Del Soldato P. Nitric-oxide releasing molecules: a new class of drugs with several major indications. Curr Pharm Des 2002; 8: 201-213.
10. Masters KS, Leibovich SJ, Belem P, West JL, Poole-Warren LA. Effects of nitric oxide releasing poly (vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice. Wound Repair Regen 2002; 10: 286-294.
11. Bauer JA, Rao W, Smith DJ. Evaluation of linear polyethyleneimine/nitric oxide adduct on wound repair: Therapy versus toxicity. Wound Repair Regen 1998; 6: 569-577.
12. Richardson G, Benjamin N. Potential therapeutic uses for S-nitrosothiols. Clin Sci (Lond) 2002; 102: 99-105.
13. Langford EJ, Brown AS, Wainwright RJ et al. Inhibition of platelet activity by S-nitrosoglutathione during coronary angioplasty. Lancet 1994; 344: 1458-1460.
14. de Belder A, Lees C, Martin J, Moncada S, Campbell S. Treatment of HELLP syndrome with nitric oxide donor. Lancet 1995; 345: 124-125.
15. Langford EJ, Wainwright RJ, Martin JF. Platelet activation in acute myocardial infarction and unstable angina is inhibited by nitric oxide donors. Arterioscler Thromb Vasc Biol 1996; 16: 51-55.
16. Stamler JS. S-nitrosothiols and the bioregulatory actions of nitrogen oxides through reactions with thiols groups. Curr Tropics Microbiol Immunol 1955; 196: 19-36.
17. Shishido SM, Seabra AB, Loh W, Ganzarolli de Oliveira M. Thermal and photochemical nitric oxide release from S-nitrosothiols incorporated in Pluronic F127 gel: Potential uses for local and controlled nitric oxide release. Biomaterials 2003; 24: 3543-3553.
18. Wang YY, Hong CT, Fang JY. In vitro and in vivo evaluations of topically applied capsaicin and nonivamide from hydrogels. Int J Pharm 2001; 224: 89-104.
19. Morishita M, Barichello JM, Takayama K et al. Pluronic F-127 gels incorporating highly purified unsaturated fatty acids for buccal delivery of insulin. Int J Pharm 2001; 212: 289-293.
20. Barreiro-Iglesias R, Alvarez-Lorenzo C, Concheiro A. A controlled release of estradiol solubilized in carbopol/surfactant aggregates. J Control Release 2003; 93: 319-330.
21. Pisal SS, Paradkar AR, Mahadik KR, Kadam SS. Pluronic gels for nasal delivery of Vitamin B12. Part I: Preformulation study. Int J Pharm 2004; 270: 37-45.
22. El-Kamel AH. In vitro and in vivo evaluation of Pluronic F127-based ocular delivery system for timolol maleate. Internat J Pharm Sci 2002; 241: 47-55.
23. Seabra AB, Fitzpatrick A, Paul J, De Oliveira MG, Weller R. Topically applied S-nitrosothiol-containing hydrogels as experimental and pharmacological nitric oxide donors in human skin. Br J Dermatol 2004; 151: 977-983.
24. Souza BR, Cardoso JF, Amadeu TP, Desmouliere A, Costa AM. Sympathetic denervation accelerates wound contraction but delays reepithelialization in rats. Wound Repair Regen 2005; 13: 498-505.
25. Amadeu TP, Costa AMA. Nitric oxide synthesis inhibition alters rat cutaneous wound healing. J Cut Pathol 2006; 33: 465-473.
26. Weller R. Nitric oxide - a newly discovered chemical transmitter in human skin. Br J Dermatol 1997; 137: 665-672.
27. Baudoin JE, Tachon P. Constitutive nitric oxide synthase is present in normal keratinocytes. J Invest Dermatol 1996; 106: 428-431.
28. Jackson M, Frane F, Weller R, McKenzie RC. Expression of nitric oxide synthase III (eNOS) mRNA by human skin cells: Melanocytes but not keratinocytes express eNOS mRNA. Arch Dermatol Res 1998; 290: 249-258.
29. Morhenn VB. Langerhans cells may trigger the psoriatic disease process via production of nitric oxide. Immunol Today 1997; 18: 433-436.
30. Wang R, Ghahary A, Shen YJ, Scott PG, Tredget EE. Human dermal fibroblasts produce nitric oxide and express both constitutive and inducible nitric oxide synthase isoforms. J Invest Dermatol 1996; 106: 419-427.
31. Schwentker A, Vodovotz Y, Weller R, Billiar TR. Nitric oxide and wound repair: Role of cytokines? Nitric Oxide 2002; 7: 1-10.
32. Schaffer MR, Tantry U, Thornton FJ, Barbul A. Inhibition of nitric oxide synthesis in wounds: Pharmacology and effect on accumulation of collagen in wounds in mice. Eur J Surg 1999; 165: 262-267.
33. Yamasaki K, Edington HD, McClosky C et al. Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer. J Clin Invest 1998; 101: 967-971.
34. Shabani M, Pulfer SK, Bulgin JP, Smith DJ. Enhancement of wound repair with a topically applied nitric oxide-realising polymer. Wound Repair Regen 1996; 4: 309-318A.
35. Mittermayr R, Valentini D, Fitzal F et al. Protective effect of a novel NO-donor on ischemia/reperfusion injury in a rat epigastric flap model. Wound Repair Regen 2003; 11: 1-93.
36. Shi HP, Most D, Efron DT et al. The role of iNOS in wound healing. Surgery 2001; 130: 225-229.
37. Horan MP, Quan N, Subramanian SV et al. Impaired wound contraction and delayed myofibroblast differentiation in restraint-stressed mice. Brain Behav Immun 2005; 19: 207-216.
38. Darby I, Skalli O, Gabbiani G. Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest 1990; 63: 21-29.
39. Bauer JA. Hydroxocobalamins as biologically compatible donors of nitric oxide implicated in the acceleration of wound healing. Med Hypotheses 1998; 51: 65-67.
40. Desmouliere A, Chaponnier C, Gabbiani G. Tissue repair, contraction, and the myofibroblast. Wound Repair Regen 2005; 13: 7-12.
41. Brown LF, Yeo KT, Berse B et al. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med 1992; 176: 1375-1379.
42. Frank S, Stallmeyer B, Kampfer H, Kolb N, Pfeilschifter J. Nitric oxide triggers enhanced induction of vascular endothelial growth factor expression in cultured keratinocytes (HaCaT) and during cutaneous wound repair. Faseb J 1999; 13: 2002-2014.
43. Stallmeyer B, Kampfer H, Kolb N, Pfeilschifter J, Frank S. The function of nitric oxide in wound repair: Inhibition of inducible nitric oxide-synthase severely impairs wound reepithelialization. J Invest Dermatol 1999; 113: 1090-1098.
44. Nill MR, Oberyszyn TM, Ross MS, Oberyszyn AS, Robertson FM. Temporal sequence of pulmonary cytokine gene expression in response to endotoxin in C3H/HeN endotoxin-sensitive and C3H/HeJ endotoxin-resistant mice. J Leukoc Biol 1995; 58: 563-574.
45. Barbul A, Lazarou SA, Efron DT, Wasserkrug HL, Efron G. Arginine enhances wound healing and lymphocyte immune responses in humans. Surgery 1990; 108: 331-336; discussion 336-337.
46. Shukla A, Rasik AM, Shankar R. Nitric oxide inhibits wounds collagen synthesis. Mol Cell Biochem 1999; 200: 27-33.
47. Witte MB, Thornton FJ, Efron DT, Barbul A. Enhancement of fibroblast collagen synthesis by nitric oxide. Nitric Oxide 2000; 4: 572-582.
48. Masini E, Salvemini D, Pistelli A, Mannaioni PF, Vane JR. Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine. Agents Actions 1991; 33: 61-63.
49. Gaboury JP, Niu XF, Kubes P. Nitric oxide inhibits numerous features of mast cell-induced inflammation. Circulation 1996; 93: 318-326.
50. Eastmond NC, Banks EM, Coleman JW. Nitric oxide inhibits IgE-mediated degranulation of mast cells and is the principal intermediate in IFN-gamma-induced suppression of exocytosis. J Immunol 1997; 159: 1444-1450.
51. Forsythe P, Gilchrist M, Kulka M, Befus AD. Mast cells and nitric oxide: control of production, mechanisms of response. Int Immunopharmacol 2001; 1: 1525-1541.
52. Maurer M, Theoharides T, Granstein RD et al. What is the physiological function of mast cells? Exp Dermatol 2003; 12: 886-910.
53. Deschoolmeester ML, Eastmond NC, Dearman RJ et al. Reciprocal effects of interleukin-4 and interferon-gamma on immunoglobulin E-mediated mast cell degranulation: A role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate. Immunology 1999; 96: 138-144.