메뉴 건너뛰기




Volumn 67, Issue 10, 2007, Pages 4537-4540

Von Hippel-Lindau: A tumor suppressor links microtubules to ciliogenesis and cancer development

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; VON HIPPEL LINDAU PROTEIN;

EID: 34250320400     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-0391     Document Type: Review
Times cited : (50)

References (31)
  • 2
    • 4644363095 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene and kidney cancer
    • Kaelin WG, Jr. The von Hippel-Lindau tumor suppressor gene and kidney cancer. Clin Cancer Res 2004;10:6290-5S.
    • (2004) Clin Cancer Res , vol.10
    • Kaelin Jr., W.G.1
  • 3
    • 33846199233 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: Central regulators of the tumor phenotype
    • Gordan JD, Simon MC. Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev 2007;17:71-7.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 71-77
    • Gordan, J.D.1    Simon, M.C.2
  • 4
    • 33746427905 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein: Roles in cancer and oxygen sensing
    • Kaelin WG. The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing. Cold Spring Harb Symp Quant Biol 2005;70:159-66.
    • (2005) Cold Spring Harb Symp Quant Biol , vol.70 , pp. 159-166
    • Kaelin, W.G.1
  • 5
    • 0029847090 scopus 로고    scopus 로고
    • Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients
    • Lubensky IA, Gnarra JR, Bertheau P, Walther MM, Linehan WM, Zhuang Z. Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients. Am J Pathol 1996;149:2089-94.
    • (1996) Am J Pathol , vol.149 , pp. 2089-2094
    • Lubensky, I.A.1    Gnarra, J.R.2    Bertheau, P.3    Walther, M.M.4    Linehan, W.M.5    Zhuang, Z.6
  • 6
    • 33747851112 scopus 로고    scopus 로고
    • Renal cystic diseases: Diverse phenotypes converge on the cilium/centrosome complex
    • Guay-Woodford LM. Renal cystic diseases: diverse phenotypes converge on the cilium/centrosome complex. Pediatr Nephrol 2006;21:1369-76.
    • (2006) Pediatr Nephrol , vol.21 , pp. 1369-1376
    • Guay-Woodford, L.M.1
  • 7
    • 16244368607 scopus 로고    scopus 로고
    • Intraflagellar transport and cilia-dependent renal disease: The ciliary hypothesis of polycystic kidney disease
    • Pazour GJ. Intraflagellar transport and cilia-dependent renal disease: the ciliary hypothesis of polycystic kidney disease. J Am Soc Nephrol 2004;15:2528-36.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2528-2536
    • Pazour, G.J.1
  • 8
    • 27944469172 scopus 로고    scopus 로고
    • An incredible decade for the primary cilium: A look at a once-forgotten organelle
    • Davenport JR, Yoder BK. An incredible decade for the primary cilium: a look at a once-forgotten organelle. Am J Physiol Renal Physiol 2005;289:F1159-69.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Davenport, J.R.1    Yoder, B.K.2
  • 10
    • 0035498717 scopus 로고    scopus 로고
    • Bending the MDCK cell primary cilium increases intracellular calcium
    • Praetorius HA, Spring KR. Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 2001;184:71-9.
    • (2001) J Membr Biol , vol.184 , pp. 71-79
    • Praetorius, H.A.1    Spring, K.R.2
  • 11
    • 20944435539 scopus 로고    scopus 로고
    • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
    • Simons M, Gloy J, Ganner A, et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 2005;37:537-43.
    • (2005) Nat Genet , vol.37 , pp. 537-543
    • Simons, M.1    Gloy, J.2    Ganner, A.3
  • 12
    • 27144460671 scopus 로고    scopus 로고
    • Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
    • Ross AJ, May-Simera H, Eichers ER, et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet 2005;37:1135-40.
    • (2005) Nat Genet , vol.37 , pp. 1135-1140
    • Ross, A.J.1    May-Simera, H.2    Eichers, E.R.3
  • 13
    • 33745819269 scopus 로고    scopus 로고
    • Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein
    • Esteban MA, Harten SK, Tran MG, Maxwell PH. Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein. J Am Soc Nephrol 2006;17:1801-6.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1801-1806
    • Esteban, M.A.1    Harten, S.K.2    Tran, M.G.3    Maxwell, P.H.4
  • 14
    • 33746886185 scopus 로고    scopus 로고
    • Primary cilium formation requires von Hippel-Lindau gene function in renal-derived cells
    • Lutz MS, Burk RD. Primary cilium formation requires von Hippel-Lindau gene function in renal-derived cells. Cancer Res 2006;66:6903-7.
    • (2006) Cancer Res , vol.66 , pp. 6903-6907
    • Lutz, M.S.1    Burk, R.D.2
  • 15
    • 33751209189 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth
    • Schermer B, Ghenoiu C, Bartram M, et al. The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth. J Cell Biol 2006;175:547-54.
    • (2006) J Cell Biol , vol.175 , pp. 547-554
    • Schermer, B.1    Ghenoiu, C.2    Bartram, M.3
  • 16
    • 0037223823 scopus 로고    scopus 로고
    • Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
    • Hergovich A, Lisztwan J, Barry R, Ballschmieter P, Krek W. Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. Nat Cell Biol 2003;5:64-70.
    • (2003) Nat Cell Biol , vol.5 , pp. 64-70
    • Hergovich, A.1    Lisztwan, J.2    Barry, R.3    Ballschmieter, P.4    Krek, W.5
  • 17
    • 1642265093 scopus 로고    scopus 로고
    • Cortical control of microtubule stability and polarization
    • Gundersen GG, Gomes ER, Wen Y. Cortical control of microtubule stability and polarization. Curr Opin Cell Biol 2004;16:106-12.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 106-112
    • Gundersen, G.G.1    Gomes, E.R.2    Wen, Y.3
  • 18
    • 0344663968 scopus 로고    scopus 로고
    • Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia
    • Hurd TW, Fan S, Liu CJ, Kweon HK, Hakansson K, Margolis B. Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia. Curr Biol 2003;13:2082-90.
    • (2003) Curr Biol , vol.13 , pp. 2082-2090
    • Hurd, T.W.1    Fan, S.2    Liu, C.J.3    Kweon, H.K.4    Hakansson, K.5    Margolis, B.6
  • 19
    • 4344659154 scopus 로고    scopus 로고
    • Polarity proteins control ciliogenesis via kinesin motor interactions
    • Fan S, Hurd TW, Liu CJ, et al. Polarity proteins control ciliogenesis via kinesin motor interactions. Curr Biol 2004;14:1451-61.
    • (2004) Curr Biol , vol.14 , pp. 1451-1461
    • Fan, S.1    Hurd, T.W.2    Liu, C.J.3
  • 20
    • 33846785192 scopus 로고    scopus 로고
    • Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells
    • Dawe HR, Farr H, Gull K. Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells. J Cell Sci 2007;120:7-15.
    • (2007) J Cell Sci , vol.120 , pp. 7-15
    • Dawe, H.R.1    Farr, H.2    Gull, K.3
  • 21
    • 0037434790 scopus 로고    scopus 로고
    • Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity
    • Etienne-Manneville S, Hall A. Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity. Nature 2003;421:753-6.
    • (2003) Nature , vol.421 , pp. 753-756
    • Etienne-Manneville, S.1    Hall, A.2
  • 22
    • 4444360489 scopus 로고    scopus 로고
    • EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration
    • Wen Y, Eng CH, Schmoranzer J, et al. EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration. Nat Cell Biol 2004;6:820-30.
    • (2004) Nat Cell Biol , vol.6 , pp. 820-830
    • Wen, Y.1    Eng, C.H.2    Schmoranzer, J.3
  • 24
    • 0037115494 scopus 로고    scopus 로고
    • Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
    • Morgan D, Eley L, Sayer J, et al. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum Mol Genet 2002;11:3345-50.
    • (2002) Hum Mol Genet , vol.11 , pp. 3345-3350
    • Morgan, D.1    Eley, L.2    Sayer, J.3
  • 26
    • 33846605643 scopus 로고    scopus 로고
    • Intraflagellar transport protein 27 is a small G protein involved in cell-cycle control
    • Qin H, Wang Z, Diener D, Rosenbaum J. Intraflagellar transport protein 27 is a small G protein involved in cell-cycle control. Curr Biol 2007;17:193-202.
    • (2007) Curr Biol , vol.17 , pp. 193-202
    • Qin, H.1    Wang, Z.2    Diener, D.3    Rosenbaum, J.4
  • 27
    • 22344445826 scopus 로고    scopus 로고
    • Cilia and the cell cycle?
    • Quarmby LM, Parker JD. Cilia and the cell cycle? J Cell Biol 2005;169:707-10.
    • (2005) J Cell Biol , vol.169 , pp. 707-710
    • Quarmby, L.M.1    Parker, J.D.2
  • 28
    • 0038739131 scopus 로고    scopus 로고
    • O'Connell MJ, Krien MJ, Hunter T. Never say never. The NIMA-related protein kinases in mitotic control. Trends Cell Biol 2003;13:221-8.
    • O'Connell MJ, Krien MJ, Hunter T. Never say never. The NIMA-related protein kinases in mitotic control. Trends Cell Biol 2003;13:221-8.
  • 29
    • 33645904854 scopus 로고    scopus 로고
    • NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes
    • Mahjoub MR, Trapp ML, Quarmby LM. NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes. J Am Soc Nephrol 2005;16:3485-9.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3485-3489
    • Mahjoub, M.R.1    Trapp, M.L.2    Quarmby, L.M.3
  • 30
    • 1542395668 scopus 로고    scopus 로고
    • Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors
    • Bowers AJ, Boylan JF. Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors. Gene 2004;328:135-42.
    • (2004) Gene , vol.328 , pp. 135-142
    • Bowers, A.J.1    Boylan, J.F.2
  • 31
    • 33746171099 scopus 로고    scopus 로고
    • The primary cilium in cell signaling and cancer
    • Michaud EJ, Yoder BK. The primary cilium in cell signaling and cancer. Cancer Res 2006;66:6463-7.
    • (2006) Cancer Res , vol.66 , pp. 6463-6467
    • Michaud, E.J.1    Yoder, B.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.