Effects of system geometry and other physical factors on photon sensitivity of high-resolution positron emission tomography

Physics in Medicine and Biology

Volumn 52, Issue 13, 2007, Pages 3753-3772

  Habte, F ^a   Foudray, A M K ^b,c   Olcott, P D ^b   Levin, C S ^b  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; PHOTODIODES; POSITRON EMISSION TOMOGRAPHY; SCINTILLATION; SENSITIVITY ANALYSIS; SIGNAL TO NOISE RATIO; ZINC;

CRYSTAL ARRAYS; LUTETIUM OXYORTHOSILICATE (LSO); PHOTON INTERACTIONS; PHOTON SENSITIVITY; POSITION-SENSITIVE AVALANCHE PHOTODIODES (PSAPD); SYSTEM GEOMETRY;

PHOTONS;

ARTICLE; COMPTON EFFECT; DETECTOR; DEVICE; GEOMETRY; IMAGING; MONTE CARLO METHOD; PHOTON; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ANIMALS; CADMIUM COMPOUNDS; COMPUTER SIMULATION; CRYSTALLIZATION; EQUIPMENT DESIGN; IMAGE PROCESSING, COMPUTER-ASSISTED; LUTETIUM; MONTE CARLO METHOD; PHOTONS; POSITRON-EMISSION TOMOGRAPHY; SENSITIVITY AND SPECIFICITY; SILICATES; TELLURIUM; TRANSDUCERS; ZINC;

EID: 34250304366     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/52/13/007     Document Type: Article

References (49)

1. Bloomfield P M, Myers R, Hume S P, Spinks T J, Lammertsma A A and Jones T 1997 Three-dimensional performance of a small-diameter positron emission tomograph Phys. Med. Biol 42 389-400
2. Brambilla M, Secco C, Dominetto M, Matheoud R, Sacchetti G and Inglese E 2005 Performance characteristics obtained for a new 3-dimensional lutetium oxyorthosilicate-based whole-body PET/CT scanner with the National Electrical Manufacturers Association NU 2-2001 Standard J. Nucl. Med 46 2083-91
3. Burr K C, Ivan A, Castleberry D E, LeBlanc J W, Shah K S and Farrell R 2004 Evaluation of a prototype small-animal PET detector with depth-of-interaction encoding IEEE Trans. Nucl. Sci. 51 1791-8 Part 1
4. Cherry S R 2004 In vivo molecular and genomic imaging: new challenges for imaging physics Phys. Med. Biol. 49 R13-48
5. Cherry S R et al 1997 MicroPET: a high resolution PET scanner for imaging small animals IEEE Trans. Nucl. Sci 44 1161
6. Chinn G, Foudray A M K and Levin C S 2005 Comparing geometries for a PET system with 3-D photon positioning capability IEEE Nuclear Science Symp. Conf. Record vol 3 pp 23-9
7. Domenico G D, Motta A, Zavattini G, Guerra A D, Damiani C, Bettinardi V and Gilardi M C 2002 Characterization of the Ferrara animal PET scanner Nucl. Instrum. Methods 477 505-8
8. Eriksson L et al 2005 Potential for a fifth generation PET scanner for oncology IEEE Nuclear Science Symp. Conf. Record vol 4 pp 23-9
9. Foudray A M K, Levin C S and Olcott P D 2005 Investigating positioning algorithms for high resolution positron emission tomography systems capable of depth of interaction measurement J. Nucl. Med. 46 483P
10. Hirschman H R et al 2000 Seeing is believing: non-invasive, quantitative and repetitive imaging of reporter gene expression in living animals, using positron emission tomography J. Neurosci. Res. 59 699-705
11. Huber J S and Moses W W 1999 Conceptual design of a high-sensitivity small animal PET camera with 4p coverage IEEE Trans. Nucl. Sci 46 498-502
12. Karp J S, Freifelder R, Kinahan P E, Geagan M J, Muehllehner G, Shao L and Lewitt R M 1994 Evaluation of volume imaging with the HEAD PENN-PET scanner 1994 IEEE Nuclear Science Symp. and Medical Imaging Conf. pp 1877-81
13. Knoess C et al 2003 Performance evaluation of the microPET R4 PET scanner for redents Eur. J. Nucl. Med. Mol. Imaging 30 737-47
14. Jeavons A P, Chandler R A and Dettmar C A R 1998 A 3D HIDAC-PET camera with sub-millimeter resolution for imaging small animal IEEE Trans. Nucl. Sci. 52 1396-400
15. Jinyi Qi, Kuo C, Huesman R H, Klein G J, Moses W W and Reutter B W 2002 Comparison of rectangular and dual-planar positron emission mammography IEEE Trans. Nucl. Sci. 51 1791-8 (Part 1)
16. Laforest R, Longford D, Siegel S, Newport D F and Yap J 2004 Performance evaluation of the microPET-focus-F120 2004 IEEE Nuclear Science Symp. Conf. Record vol 5 pp 2965-9
17. Lazaro D et al 2004 Validation of the GATE Monte Carlo simulation platform for modeling a CsI(Tl) scintillation camera dedicated to small-animal imaging Phys. Med. Biol. 49 271-85
18. Lecomte R, Cadorette J, Richard P, Rodrigue S and Rouleau D 1994 Design and engineering aspects of a high resolution positron tomograph for small animal imaging IEEE Trans. Nucl. Sci. 41 1446-52
19. Levin C S 2002 Design of a high-resolution and high-sensitivity scintillation crystal array for PET with nearly complete light collection IEEE Trans. Nucl. Sci 49 2236-43
20. Levin C S 2003 Detector design issues for compact nuclear emission cameras dedicated to breast imaging Nucl. Instrum. Methods A 497 60-74
21. Levin C S, Foudray A M K, Olcott P D and Habte F 2004a Investigation of position sensitive avalanche photodiodes for a new high-resolution PET detector design IEEE Trans. Nucl. Sci. 51 805-10
22. Levin C S and Hoffman E J 1999 Calculation of positron range and its effect on positron emission tomography system spatial resolution Phys.Med. Biol. 44 781-99
23. Levin C S, Matteson J L, Skelton R T, Pelling M R and Duttweiler F 2004b Promising characteristics and performance of cadmium zinc telluride detectors for positron emission tomography Presented at 2004 IEEE Nuclear Science Symp. and Medical Imaging Conf. (Rome, Italy, 16-22 Oct.) Abstract no. M2-117/Book of Abstracts/p 136/IEEE/Nuclear and Plasma Science Society
24. Levin C S, Habte F, Foudray A M K, Zhang J and Chinn G 2007 Impact of high energy resolution detectors on the performance of a PET system dedicated to breast cancer imaging Physica Med. XXI (Suppl. 1) 28-34
25. McConnell M L et al 2000 Three-dimensional imaging and detection efficiency performance of orthogonal coplanar CZTs trip detectors Proc. SPIE 4141 157-67
26. McElroy D P et al 2005 A true singles list-mode data acquisition system for small animal PET scanner with independent crystal readout Phys. Med. Biol. 50 3323-35
27. Missimer J, Madi Zoltan, Honer M, Keller C, Schubiger A and Ametamey S M 2004 Performance evaluation of 16-module quad-HIDAC small animal PET camera Phys. Med. Biol. 49 2069-81
28. Moses W W 2001 Trends in PET Imaging Nucl. Instrum. Methods A 471 209-14
29. Moses W W, Derenzo S E, Huesman R H and Budinger T F 1997 Design of a high-resolution, high-sensitivity PET camera for human brains and small animals IEEE Trans. Nucl. Sci. 44 1487-91
30. Murthy K, Aznar M, Bergman A M, Thompson C J, Robar J L, Lisbona R, Loutfi A and Gagnon J H 2000 Positron emission mammographic instrument: initial results Radiology 215 280-5
31. Rouse N C, Schmand M, Siegel S and Hutchins G D 2004 Design of a small animal PET imaging system with 1 microliter volume resolution IEEE Trans. Nucl. Sci. 51 757-63
32. Santin G, Strul D, Lazaro D, Simon L, Krieguer M, Vieira Martins M, Breton V and Morel C 2003 GATE, a GEANT4- based simulation platform for PET integrating movement and time management IEEE Trans. Nucl. Sci. 50 1516-21
33. Schmand M, Eriksson L, Casey M E, Wienhard K, Flugge G and Nutt R 1999 Advantages using pulse shape discrimination to assign the depth of interaction information (DOI) from a multi layer phoswich detector IEEE Trans. Nucl. Sci. 46 985-90 (Part 2)
34. Simon L, Strul D, Santin G, Krieguer M and Morel C 2004 Simulation of time curves in small animal PET using GATE Nucl. Instrum. Methods A 527 190-4
35. Slavis K R et al 2000 Performance of a prototype CdZnTe detector module for hard X-ray astrophysics SPIE Symp. Proc. 4140 249-56
36. Staelens S, Strul D, Santin G, Vandenberghe S, Koole M, D'Asseler Y, Lemahieu I and Van de Walle R 2003 Monte Carlo simulations of a scintillation camera using GATE: validation and application modelling Phys. Med. Biol. 48 3021-42
37. Stickel J R and Cherry S R 2005 High-resolution PET detector design: modeling components of intrinsic spatial resolution Phys. Med. Biol. 50 179-95
38. Strulab D, Santin G, Lazaro D, Breton V and Morel C 2003 GATE (Geant4 Application for Tomographic Emission): a PET/SPECT general-purpose simulation platform Nucl. Phys. B (Proc. Suppl.) 125 75-9
39. Tai Y C, Chatziioannou A, Siegel S, Young J, Newport D, Goble R N, Nutt R E and Cherry R S 2001 Performance evaluation of the microPET P4: a PET system dedicated to animal imaging Phys. Med. Biol. 46 1845-62
40. Tai Y C, Chatziioannou A F, Yang Y, Silverman R W, Meadors K, Siegel S, Newport D F, Stickel J R and Cherry S R 2003 MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging Phys. Med. Biol. 48 1519-37
41. Tai Y C and Laforest R 2005 Instrumentation aspects of animal PET Annu. Rev. Biomed. Eng. 7 255-85
42. Tai Y C, Ruangma A, Rowland D, Siegel S, Newport D F, Chow P L and Laforest R 2005 Performance evaluation of the microPET focus: a third-generation microPET scanner dedicated to animal imaging J. Nucl. Med 46 455-63
43. Vaska P, Rubins D J, Alexoff D L and Schiffer W K 2006 Quantitative imaging with the micro-pet small animal PET tomograph Int. Rev. Neurobiol. 73 191-218
44. Wong W H, Li H, Xie S, Ramirez R, Uribe J, Wang Y, Liu Y, Xing T and Baghaei H 2003 Design of an inexpensive high-sensitivity rodent research PET (RRPET) 2003 IEEE Nuclear Science Symp. and Medical Imaging Conf. Record pp 19-25
45. Yamaya T et al 2005 The jPET-D4: imaging performance of the 4-layer depth-of-interaction PET scanner Nuclear Science Symp. Conf. Record, 2005 IEEE vol 4 pp 1977-80
46. Yang Y, Tai Y C, Siegel S, Newport D F, Bai B, Li Q, Leahy R M and Cherry S R 2004 Optimization and performance evaluation of microPET II scanner for in vivo small-animal imaging Phys. Med. Biol. 49 2527-45
47. Zhang J, Foudray A M K, Olcott P D and Levin C S 2005a Performance characterization of a novel thin position-sensitive avalanche photodiode-based detector for high resolution PET 2005 IEEE Nuclear Science Symp. and Medical Imaging Conf. Record (Piscataway, NJ, USA)
48. Zhang Y, Wong W-H, Baghaei H, Kim S, Li H, Liu J, Liu S, Ramirez R and Wang Y 2005b Performance evaluation of the low-cost high-sensitivity rodent research PET (RRPET) camera using Monte Carlo simulation 2005 IEEE Nuclear Science Symp. Conf. Record pp 2514-18
49. Ziemons K et al 2005 The ClearPET(tm) project: development of a 2nd generation high-performance small animal PET scanner Nucl. Instrum. Methods A 537 308 307-311