Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 6, 2007, Pages 2016-2027

  Yano, Masahiko ^a,b   Ikeda, Masanori ^a   Abe, Ken Ichi ^a   Dansako, Hiromichi ^a   Ohkoshi, Shogo ^b   Aoyagi, Yutaka ^b   Kato, Nobuyuki ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA TOCOPHEROL; BETA CAROTENE; BETA INTERFERON; CYCLOSPORIN; ERGOCALCIFEROL; FLUINDOSTATIN; LINOLEIC ACID;

ANIMAL CELL; ARTICLE; CELL CULTURE; DRUG EFFECT; DRUG EFFICACY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; HEPATITIS C VIRUS; NONHUMAN; PRIORITY JOURNAL; RNA REPLICATION;

AMINO ACIDS; CELL LINE, TUMOR; FATTY ACIDS; HEPACIVIRUS; HUMANS; MICRONUTRIENTS; RNA, VIRAL; SALTS; VIRUS REPLICATION; VITAMINS;

EID: 34250202525     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01426-06     Document Type: Article

References (45)

1. Alter, H. J., R. H. Purcell, J. W. Shih, J. C. Melpolder, M. Houghton, Q. L. Choo, and G. Kuo. 1989. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N. Engl. J. Med. 321:1494-1500.
2. Appel, N., T. Schaller, F. Penin, and R. Bartenschlager. 2006. From structure to function: new insights into hepatitis C virus RNA replication. J. Biol. Chem. 281:9833-9836.
3. Armas, L. A., B. W. Hollis, and R. P. Heaney. 2004. Vitamin D2 is much less effective than vitamin D3 in humans. J. Clin. Endocrinol. Metab. 89:5387-5391.
4. Blight, K. J., J. A. McKeating, and C. M. Rice. 2002. Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J. Virol. 76:13001-13014.
5. Bougie, I., S. Charpentier, and M. Bisaillon. 2003. Characterization of the metal ion binding properties of the hepatitis C virus RNA polymerase. J. Biol. Chem. 278:3868-3875.
6. Cousin, S. P., S. R. Hugl, C. E. Wrede, H. Kajio, M. G. Myers, Jr., and C. J. Rhodes. 2001. Free fatty acid-induced inhibition of glucose and insulin-like growth 'factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1. Endocrinology 142:229-240.
7. Ferencz, S., and R. Batey. 2003. Intracerebral haemorrhage and hepatitis C treatment. J. Viral Hepat. 10:401-403.
8. Ferrari, E., J. Wright-Minogue, J. W. Fang, B. M. Baroudy, J. Y. Lau, and Z. Hong. 1999. Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli. J. Virol. 73:1649-1654.
9. Fillebeen, C., A. M. Rivas-Estilla, M. Bisaillon, P. Ponka, M. Muckenthaler, M. W. Hentze, A. E. Koromilas, and K. Pantopoulos. 2005. Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C virus. J. Biol. Chem. 280:9049-9057.
10. Fried, M. W. 2002. Side effects of therapy of hepatitis C and their management. Hepatology 36:S237-S44.
11. Hadziyannis, S. J., H. Sette, Jr., T. R. Morgan, V. Balan, M. Diago, P. Marcellin, G. Ramadori, H. Bodenheimer, Jr., D. Bernstein, M. Rizzetto, S. Zeuzem, P. J. Pockros, A. Lin, and A. M. Ackrill. 2004. Peginterferon- alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann. Intern. Med. 140:346-355.
12. Hagenlocher, T., J. Nair, N. Becker, A. Korfmann, and H. Bartsch. 2001. Influence of dietary fatty acid, vegetable, and vitamin intake on etheno-DNA adducts in white blood cells of healthy female volunteers: a pilot study. Cancer Epidemiol. Biomarkers Prev. 10:1187-1191.
13. Ikeda, M., K. Abe, H. Dansako, T. Nakamura, K. Naka, and N. Kato. 2005. Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system. Biochem. Biophys. Res. Commun. 329:1350-1359.
14. Ikeda, M., K. Abe, M. Yamada, H. Dansako, K. Naka, and N. Kato. 2006. Different anti-HCV profiles of statins and their potential for combination therapy with interferon. Hepatology 44:117-125.
15. Ikeda, M., M. Yi, K. Li, and S. M. Lemon. 2002. Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells. J. Virol. 76:2997-3006.
16. Jenkins, J. K., H. Huang, K. Ndebele, and A. K. Salahudeen. 2001. Vitamin E inhibits renal mRNA expression of COX II, HO I, TGFbeta, and osteopontin in the rat model of cyclosporine nephrotoxicity. Transplantation 71:331-334.
17. Kapadia, S. B., and F. V. Chisari. 2005. Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. Proc. Natl. Acad. Sci. USA 102:2561-2566.
18. Kato, N., K. Sugiyama, K. Namba, H. Dansako, T. Nakamura, M. Takami, K. Naka, A. Nozaki, and K. Shimotohno. 2003. Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro. Biochem. Biophys. Res. Commun. 306:756-766.
19. Kliewer, S. A., J. M. Lehmann, and T. M. Willson. 1999. Orphan nuclear receptors: shifting endocrinology into reverse. Science 284:757-760.
20. Landes, N., P. Pfluger, D. Kluth, M. Birringer, R. Ruhl, G. F. Bol, H. Glatt, and R. Brigelius-Flohe. 2003. Vitamin E activates gene expression via the pregnane X receptor. Biochem. Pharmacol. 65:269-273.
21. Leu, G. Z., T. Y. Lin, and J. T. Hsu. 2004. Anti-HCV activities of selective polyunsaturated fatty acids. Biochem. Biophys. Res. Commun. 318:275-280.
22. Lexis, L. A., A. Fenning, L. Brown, R. G. Fassett, and J. S. Coombes. 2006. Antioxidant supplementation enhances erythrocyte antioxidant status and attenuates cyclosporine-induced vascular dysfunction. Am. J. Transplant. 6:41-49.
23. Liang, T. J., L. J. Jeffers, K. R. Reddy, M. De Medina, I. T. Parker, H. Cheinquer, V. Idrovo, A. Rabassa, and E. R. Schiff. 1993. Viral pathogenesis of hepatocellular carcinoma in the United States. Hepatology 18:1326-1333.
24. Lindenbach, B. D., M. J. Evans, A. J. Syder, B. Wolk, T. L. Tellinghuisen, C. C. Liu, T. Maruyama, R. O. Hynes, D. R. Burton, J. A. McKeating, and C. M. Rice. 2005. Complete replication of hepatitis C virus in cell culture. Science 309:623-626.
25. Lohmann, V., F. Korner, J. Koch, U. Herian, L. Theilmann, and R. Bartenschlager. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285:110-113.
26. Lott, W. B., S. S. Takyar, J. Tupnen, D. H. Crawford, M. Harrison, T. P. Sloots, and E. J. Gowans. 2001. Vitamin B12 and hepatitis C: molecular biology and human pathology. Proc. Natl. Acad. Sci. USA 98:4916-4921.
27. McDonnell, D. P., D. J. Mangelsdorf, J. W. Pike, M. R. Haussler, and B. W. O'Malley. 1987. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science 235:1214-1217.
28. McHutchison, J. G., and M. W. Fried. 2003. Current therapy for hepatitis C: pegylated interferon and ribavirin. Clin. Liver Dis. 7:149-161.
29. Miyamoto, S., G. R. Martinez, D. Rettori, O. Augusto, M. H. Medeiros, and P. Di Mascio. 2006. Linoleic acid hydroperoxide reacts with hypochlorous acid, generating peroxyl radical intermediates and singlet molecular oxygen. Proc. Natl. Acad. Sci. USA 103:293-298.
30. Naka, K., M. Ikeda, K. Abe, H. Dansako, and N. Kato. 2005. Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha. Biochem. Biophys. Res. Commun. 330:871-879.
31. Nakagawa, M., N. Sakamoto, Y. Tanabe, T. Koyama, Y. Itsui, Y. Takeda, C. H. Chen, S. Kakinuma, S. Oooka, S. Maekawa, N. Enomoto, and M. Watanabe. 2005. Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins. Gastroenterology 129:1031-1041.
32. Paolini, M., A. Antelli, L. Pozzetti, D. Spetlova, P. Perocco, L. Valgimigli, G. F. Pedulli, and G. Cantelli-Forti. 2001. Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats. Carcinogenesis 22:1483-1495.
33. Pietschmann, T., V. Lohmann, A. Kaul, N. Krieger, G. Rinck, G. Rutter, D. Strand, and R. Bartenschlager. 2002. Persistent and transient replication of full-length hepatitis C virus genomes in cell culture. J. Virol. 76:4008-4021.
34. Pietschmann, T., V. Lohmann, G. Rutter, K. Kurpanek, and R. Bartenschlager. 2001. Characterization of cell lines carrying self-replicating hepatitis C virus RNAs. J. Virol. 75:1252-1264.
35. Rühl, R., R. Sczech, N. Landes, P. Pfluger, D. Kluth, and F. J. Schweigert. 2004. Carotenoids and their metabolites are naturally occurring activators of gene expression via the pregnane X receptor. Eur. J. Nutr. 43:336-343.
36. Sagoe-Moses, C., R. D. Pearson, J. Perry, and J. Jagger. 2001. Risks to health care workers in developing countries. N. Engl. J. Med. 345:538-541.
37. Sanchez-Tapias, J. M., M. Diago, P. Escartin, J. Enriquez, M. Romero-Gomez, R. Barcena, J. Crespo, R. Andrade, E. Martinez-Bauer, R. Perez, M. Testillano, R. Planas, R. Sola, M. Garcia-Bengoechea, J. Garcia-Samaniego, M. Munoz-Sanchez, and R. Moreno-Otero. 2006. Peginterferon-alfa2a plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis C virus RNA at week 4 of treatment. Gastroenterology 131:451-460.
38. Tong, M. J., N. S. el-Farra, A. R. Reikes, and R. L. Co. 1995. Clinical outcomes after transfusion-associated hepatitis C. N. Engl. J. Med. 332: 1463-1466.
39. Wakita, T., T. Pietschmann, T. Kato, T. Date, M. Miyamoto, Z. Zhao, K. Murthy, A. Habermann, H. G. Krausslich, M. Mizokami, R. Bartenschlager, and T. J. Liang. 2005. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat. Med. 11:791-796.
40. Wasley, A., and M. J. Alter. 2000. Epidemiology of hepatitis C: geographic differences and temporal trends. Semin. Liver Dis. 20:1-16.
41. Watashi, K., M. Hijikata, M. Hosaka, M. Yamaji, and K. Shimotohno. 2003. Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes. Hepatology 38:1282-1288.
42. Watashi, K., N. Ishii, M. Hijikata, D. Inoue, T. Murata, Y. Miyanari, and K. Shimotohno. 2005. Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase. Mol. Cell 19:111-122.
43. Yeh, S. L., W. Y. Wang, C. S. Huang, and M. L. Hu. 2006. Flavonoids suppresses the enhancing effect of beta-carotene on DNA damage induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A549 cells. Chem. Biol. Interact. 160:175-182.
44. Yin, H., E. S. Musiek, L. Gao, N. A. Porter, and J. D. Morrow. 2005. Regiochemistry of neuroprostanes generated from the peroxidation of docosahexaenoic acid in vitro and in vivo. J. Biol. Chem. 280:26600- 26611.
45. Zhong, J., P. Gastaminza, G. Cheng, S. Kapadia, T. Kato, D. R. Burton, S. F. Wieland, S. L. Uprichard, T. Wakita, and F. V. Chisari. 2005. Robust hepatitis C virus infection in vitro. Proc. Natl. Acad. Sci. USA 102:9294-9299.