The role of cytokines in the development of normal-tissue reactions after radiotherapy

Strahlentherapie und Onkologie

Volumn 174, Issue SUPPL. 3, 1998, Pages 12-15

  Herskind, Carsten ^a   Bamberg, Michael ^a   Rodemann, Hans Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Cytokine expression; Late reactions; Radiation induced fibrosis

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CYTOKINE RELEASE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATORY CELL; INTESTINE MUCOSA; LUNG FIBROSIS; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; RADIATION INJURY; RADIATION RESPONSE; RADIOSENSITIVITY; SKIN; TISSUE REACTION; TISSUE SPECIFICITY;

ANIMALS; CYTOKINES; EXTRACELLULAR MATRIX PROTEINS; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; RADIATION INJURIES; RADIOTHERAPY; RECEPTORS, CYTOKINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031790166     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Anscher MS, Kong F-M, Marks LB, et al. Changes in plasma transforming growth factor beta during radiotherapy and the risk of symptomatic radiation-induced pneumonias. Int J Radiat Oncol Biol Phys 1997;37:253-8.
2. Barcellos-Hoff MH. Radiation-induced transforming growth factor β and subsequent extracellular matrix reorganization in the murine mammary gland. Cancer Res 1993;53:3880-6.
3. Barcellos-Hoff MH, Derynck R, Tsang ML-S, et al. Transforming growth factor-β activation in irradiated murine mammary gland. J Clin Invest 1994;93:892-9.
4. Battegay EJ, Raines EW, Seifert RA, et al. TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell 1990;63:515-24.
5. Beetz A, Messer G, Oppel T, et al. Induction of interleukin 6 by ionizing radiation in a human epithelial cell line: control by corticosteroids. Int J Radiat Biol 1997;72:33-43.
6. Bentzen SM, Skoczylas JZ, Overgaard M, et al. Radiotherapy-related lung fibrosis enhanced by tamoxifen. J Natl Cancer Inst 1996;88:918-22.
7. Canney PA, Dean S. Transforming growth factor beta: a promoter of late connective tissue injury following radiotherapy? Br J Radiol 1990;63:620-3.
8. Dinarelio CA. Interleukin-1 and interleukin-1 antagonism. Blood 1991; 77:1627-52.
9. Edwards DR, Murphy G, Reynolds JJ, et al. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J 1987;6:1899-904.
10. Ehrhart EJ, Segarini P, Tsang ML-S, et al. Latent transforming growth factor β1 activation in situ: quantitative and functional evidence after low-dose β-irradiation. FASEB J 1997;11:991-1002.
11. Farrell CL, Bready JV, Rex KL, et al. Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality. Cancer Res 1998;58:933-9.
12. Grainger DJ, Wakefield L, Bethell HW, et al. Release and activation of platelet latent TGF-β in blood clots during dissolution with plasmin. Nature Medicine 1995;1:932-7.
13. Hallahan DE, Spriggs DR, Beckett MA, et al. Increased tumor necrosis factor α mRNA after cellular exposure to ionizing radiation. Proc Natl Acad Sci USA 1989;86:10104-7.
14. Hallahan DE, Virudachalam S, Sherman ML, et al. Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation. Cancer Res 1991;51:4565-9.
15. Herskind C, Bentzen SM, Overgaard J, et al. Differentiation state of skin fibroblast cultures versus risk of subcutaneous fibrosis after radiotherapy. Radiothar Oncol 1998;47:263-9.
16. Hibi M, Nakajima K, Hirano T. IL-6 cytokine family and signal transduction: a model of the cytokine system. J Mol Med 1996;74:1-12.
17. Johnston CJ, Piedboeuf B, Baggs R, et al. Differences in correlation of mRNA gene expression in mice sensitive and resistant to radiation-induced pulmonary fibrosis. Radiat Res 1995;142:197-203.
18. Johnston CJ, Piedboeuf B, Rubin P, et al. Early and persistent alterations in the expression of interleukin-1α, interleukin-1β and tumor necrosis factor α mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation. Radiat Res 1996;145:762-7.
19. Kovacs EJ, DiPietro LA. Fibrogenic cytokines and connective tissue production. FASEB J 1994;8:854-61.
20. Langberg CW, Hauer-Jensen M, Sung C-C, et al. Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation. Radiother Oncol 1994;32:29-36.
21. Martin M, Lefaix J-L, Pinton P, et al. Temporal modulation of TGFβ1 and β-actin gene expression in pig skin and muscular fibrosis after ionizing radiation. Radiat Res 1993;134:63-70.
22. Mauviel A. Cytokine regulation of metalloproteinase gene expression. J Cell Biochem 1993;53:288-295.
23. Munger JS, Harpel JG, Gleizes P-E, et al. Latent transforming growth factor-β: Structural features and mechanisms of activation. Kidney Int 1997;51:1376-82.
24. O'Brien-Ladner A, Nelson ME, Kimler BF, et al. Release of interleukin-1 by human alveolar macrophages after in vitro irradiation. Radiat Res 1993;136:37-41.
25. Paulsson Y, Austgulen R, Hofsli et al. Tumor necrosis factor-induced expression of platelet-derived growth factor A-chain messenger RNA in fibroblasts. Exp Cell Res 1989;180:490-6.
26. Raines EW, Dower SK, Ross R. Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science 1989;243:393-6.
27. Randall K, Coggle JE. Long-term expression of transforming growth factor beta 1 in mouse skin after localized beta-irradiation. Int J Radiat Biol 1996;70:351-60.
28. Richter KK, Langberg CW, Sung C-C, et al. Association of transforming growth factor β (TGFβ) immunoreactivity with histopathotogical lesions in subacute and chronic experimental radiation enteropathy. Radiother Oncol 1996;39:243-51.
29. Richter KK, Langberg CW, Sung C-C, et al. Increased transforming growth factor β (TGFβ) immunoreactivity is independently associated with chronic injury in both consequential and primary radiation enteropathy. Int J Radiat Oncol Biol Phys 1997;39:187-95.
30. Rodemann HP, Bamberg M. Cellular basis of radiation-induced fibrosis. Radiother Oncol 1995; 35:83-90.
31. Rubin P, Finkelstein J, Shapiro D. Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes: interrelationship between the alveolar macrophage and the septal fibroblast. Int J Radiat Oncol Biol Phys 1992;24:93-101.
32. Rubin P, Johnston CJ, Williams JP, et al. A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis. Int J Radiat Oncol Biol Phys 1995;33:99-109.
33. Rübe C, Finke C, van Valen F, et al. Nachweis einer strahleninduzierten Produktion von Tumor-Nekrose-Faktor alpha im Ewing-Sarkom RM82 in vitro und in vivo. Strahlenther Onkol 1997;173:407-14.
34. Varga J, Rosenbloom J, Jimenez SA. Transforming growth factor β (TGFβ) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human fibroblasts. Biochem J 1987;247:597-604.
35. Wang J, Robbins MEC. Radiation-induced alteration of rat mesangial cell transforming growth factor-ß and expression of the genes associated with the extracellular matrix. Radiat Res 1996;146:561-8.
36. Wasserman J, Petrini B, Wolk G, et al. Cytokine release from mononuclear cells in patients irradiated for breast cancer. Anticancer Res 1991;11:461-4.
37. Woloschak GE, Chang-Liu C-M, Jones PS, et al. Modulation of gene expression in Syrian hamster embryo cells following ionizing radiation. Cancer Res 1990;50:339-44.