Synthesis of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) with thermostabilized low-specific L-threonine aldolase from Streptomyces coelicolor A3(2)

Journal of Microbiology and Biotechnology

Volumn 17, Issue 5, 2007, Pages 721-727

  Baik, Sang Ho ^a,c   Yoshioka, Hideki ^b,d   Yukawa, Hideaki ^b   Harayama, Shigeaki ^a  

^a NATIONAL INSTITUTE OF TECHNOLOGY AND EVALUATION   (Japan)

^b RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH   (Japan)

^c Korea Atomic Energy Research Institute   (South Korea)

^d Pharmaceutical Devmt Res Labs   (Japan)

Author keywords

In vitro mutagenesis; L threo DOPS; L threonine aldolase; Thermostability

Indexed keywords

FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCINE; PROTOCATECHUALDEHYDE; THREO 3,4 DIHYDROXYPHENYLSERINE; THREONINE ALDOLASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO ACID SYNTHESIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EXPRESSION; HALF LIFE TIME; HIGH THROUGHPUT SCREENING; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; STREPTOMYCES COELICOLOR; TEMPERATURE MEASUREMENT; THERMOSTABILITY; WILD TYPE;

AMINO ACID SUBSTITUTION; BENZALDEHYDES; CATECHOLS; CLONING, MOLECULAR; DNA MUTATIONAL ANALYSIS; DNA, BACTERIAL; DROXIDOPA; ENZYME STABILITY; ESCHERICHIA COLI; GENE EXPRESSION; GLYCINE; GLYCINE HYDROXYMETHYLTRANSFERASE; HALF-LIFE; HEAT; MUTATION, MISSENSE; POLYMERASE CHAIN REACTION; STREPTOMYCES COELICOLOR;

ESCHERICHIA COLI; STREPTOMYCES COELICOLOR;

EID: 34250186111     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: None     Document Type: Article

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