Gene cloning and overproduction of low-specificity D-threonine aldolase from Alcaligenes xylosoxidans and its application for production of a key intermediate for parkinsonism drug

Applied Microbiology and Biotechnology

Volumn 54, Issue 1, 2000, Pages 44-51

  Liu, J Q ^a,c   Odani, M ^a   Yasuoka, T ^a   Dairi, T ^a   Itoh, N ^a   Kataoka, M ^b   Shimizu, S ^b   Yamada, H ^a  

^a TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM SULFATE; ANTIPARKINSON AGENT; BACTERIAL DNA; FRUCTOSE BISPHOSPHATE ALDOLASE; LEVO BETA 3,4 METHYLENEDIOXYPHENYLSERINE; PYRIDOXAL 5 PHOSPHATE; THREO 3,4 DIHYDROXYPHENYLSERINE; UNCLASSIFIED DRUG;

ACHROMOBACTER XYLOSOXIDANS; ALCALIGENES; AMINO ACID SEQUENCE; ARTHROBACTER; ARTICLE; CATALYST; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PARKINSON DISEASE;

ALCALIGENES; AMINO ACID SEQUENCE; ANTIPARKINSON AGENTS; BASE SEQUENCE; CLONING, MOLECULAR; DNA PRIMERS; DNA, BACTERIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GLYCINE HYDROXYMETHYLTRANSFERASE; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

ACHROMOBACTER XYLOSOXIDANS; ALCALIGENES; ARTHROBACTER; ARTHROBACTER SP.; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA;

EID: 0033912395     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002539900301     Document Type: Article

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