메뉴 건너뛰기




Volumn 147, Issue 2, 2007, Pages 456-468

Morphine preferentially activates the periaqueductal gray-rostral ventromedial medullary pathway in the male rat: A potential mechanism for sex differences in antinociception

Author keywords

endogenous descending pathway; morphine analgesia; opioid; pain; pain inhibition; sexual dimorphism

Indexed keywords

MORPHINE SULFATE; PROTEIN FOS;

EID: 34250182734     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2007.03.053     Document Type: Article
Times cited : (69)

References (70)
  • 1
    • 0028101302 scopus 로고
    • Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?
    • Bandler R., and Shipley M.T. Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?. Trends Neurosci 19 (1994) 379-389
    • (1994) Trends Neurosci , vol.19 , pp. 379-389
    • Bandler, R.1    Shipley, M.T.2
  • 2
    • 0034749640 scopus 로고    scopus 로고
    • Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids
    • Barrett A.C., Cook C.D., Terner J.M., Craft R.M., and Picker M.J. Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids. Psychopharmacology (Berl) 158 (2001) 154-164
    • (2001) Psychopharmacology (Berl) , vol.158 , pp. 154-164
    • Barrett, A.C.1    Cook, C.D.2    Terner, J.M.3    Craft, R.M.4    Picker, M.J.5
  • 3
    • 0024638572 scopus 로고
    • Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction
    • Bartel D.P., Sheng M., Lau L.F., and Greenberg M.E. Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction. Genes Dev 3 (1989) 304-313
    • (1989) Genes Dev , vol.3 , pp. 304-313
    • Bartel, D.P.1    Sheng, M.2    Lau, L.F.3    Greenberg, M.E.4
  • 4
    • 0030741986 scopus 로고    scopus 로고
    • Sex differences in opioid antinociception
    • Bartok R.E., and Craft R.M. Sex differences in opioid antinociception. J Pharmacol Exp Ther 282 (1997) 769-778
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 769-778
    • Bartok, R.E.1    Craft, R.M.2
  • 5
    • 0018138322 scopus 로고
    • Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems
    • Basbaum A.I., Clanton C.H., and Fields H.L. Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems. J Comp Neurol 178 (1978) 209-224
    • (1978) J Comp Neurol , vol.178 , pp. 209-224
    • Basbaum, A.I.1    Clanton, C.H.2    Fields, H.L.3
  • 6
    • 0018159356 scopus 로고
    • Endogenous pain control mechanisms: review and hypothesis
    • Basbaum A.I., and Fields H.L. Endogenous pain control mechanisms: review and hypothesis. Ann Neurol 4 (1978) 451-462
    • (1978) Ann Neurol , vol.4 , pp. 451-462
    • Basbaum, A.I.1    Fields, H.L.2
  • 7
    • 0021288912 scopus 로고
    • Endogenous pain control systems: Brainstem spinal pathways and endorphin circuitry
    • Basbaum A.I., and Fields H.L. Endogenous pain control systems: Brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci 7 (1984) 309-338
    • (1984) Annu Rev Neurosci , vol.7 , pp. 309-338
    • Basbaum, A.I.1    Fields, H.L.2
  • 8
    • 0025054545 scopus 로고
    • Hyperalgesia during naloxone-precipitated withdrawal from morphine is associated with increased on-cell activity in the rostral ventromedial medulla
    • Bederson J.B., Fields H.L., and Barbaro N.M. Hyperalgesia during naloxone-precipitated withdrawal from morphine is associated with increased on-cell activity in the rostral ventromedial medulla. Somatosens Mot Res 7 (1990) 185-203
    • (1990) Somatosens Mot Res , vol.7 , pp. 185-203
    • Bederson, J.B.1    Fields, H.L.2    Barbaro, N.M.3
  • 9
    • 0025009190 scopus 로고
    • The effect of [Met]enkephalin on the periaqueductal gray neurons of the rat: an in vitro study
    • Behbehani M.M., Jiang M., and Chandler S.D. The effect of [Met]enkephalin on the periaqueductal gray neurons of the rat: an in vitro study. Neuroscience 38 (1990) 373-380
    • (1990) Neuroscience , vol.38 , pp. 373-380
    • Behbehani, M.M.1    Jiang, M.2    Chandler, S.D.3
  • 10
    • 0025037644 scopus 로고
    • The effect of GABA and its antagonists on midbrain periaqueductal gray neurons in the rat
    • Behbehani M.M., Jiang M.R., Chandler S.D., and Ennis M. The effect of GABA and its antagonists on midbrain periaqueductal gray neurons in the rat. Pain 40 (1990) 195-204
    • (1990) Pain , vol.40 , pp. 195-204
    • Behbehani, M.M.1    Jiang, M.R.2    Chandler, S.D.3    Ennis, M.4
  • 11
    • 0000171852 scopus 로고
    • Reticular formation, central gray and related tegmental nuclei
    • Paxinos G. (Ed), Academic Press Australia, Sydney
    • Beitz A.J. Reticular formation, central gray and related tegmental nuclei. In: Paxinos G. (Ed). The rat nervous system (1985), Academic Press Australia, Sydney 1-28
    • (1985) The rat nervous system , pp. 1-28
    • Beitz, A.J.1
  • 12
    • 0021857965 scopus 로고
    • The midbrain periaqueductal gray in the rat. I. Nuclear volume, cell number, density, orientation, and regional subdivisions
    • Beitz A.J. The midbrain periaqueductal gray in the rat. I. Nuclear volume, cell number, density, orientation, and regional subdivisions. J Comp Neurol 237 (1985) 445-459
    • (1985) J Comp Neurol , vol.237 , pp. 445-459
    • Beitz, A.J.1
  • 13
    • 0020679017 scopus 로고
    • The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin
    • Beitz A.J., Shepard R.D., and Wells W.E. The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin. Brain Res 261 (1983) 132-137
    • (1983) Brain Res , vol.261 , pp. 132-137
    • Beitz, A.J.1    Shepard, R.D.2    Wells, W.E.3
  • 14
    • 0031929829 scopus 로고    scopus 로고
    • Swim-stress but not opioid withdrawal increases expression of c-Fos immunoreactivity in rat periaqueductal gray neurons which project to the rostral ventromedial medulla
    • Bellchambers C.E., Chieng B., Keay K.A., and Christie M.J. Swim-stress but not opioid withdrawal increases expression of c-Fos immunoreactivity in rat periaqueductal gray neurons which project to the rostral ventromedial medulla. Neuroscience 83 2 (1998) 517-524
    • (1998) Neuroscience , vol.83 , Issue.2 , pp. 517-524
    • Bellchambers, C.E.1    Chieng, B.2    Keay, K.A.3    Christie, M.J.4
  • 15
    • 33846013254 scopus 로고    scopus 로고
    • PAG mu opioid receptor activation underlies sex differences in morphine antinociception
    • Bernal S.A., Morgan M.M., and Craft R.M. PAG mu opioid receptor activation underlies sex differences in morphine antinociception. Behav Brain Res 177 (2007) 126-133
    • (2007) Behav Brain Res , vol.177 , pp. 126-133
    • Bernal, S.A.1    Morgan, M.M.2    Craft, R.M.3
  • 16
    • 0024161140 scopus 로고
    • Organismic variables and pain inhibition: roles of gender and aging
    • Bodnar R.J., Romero M.T., and Kramer E. Organismic variables and pain inhibition: roles of gender and aging. Brain Res Bull 21 (1988) 947-953
    • (1988) Brain Res Bull , vol.21 , pp. 947-953
    • Bodnar, R.J.1    Romero, M.T.2    Kramer, E.3
  • 17
    • 0032526578 scopus 로고    scopus 로고
    • Microinjection of morphine into the rostral ventromedial medulla produces greater antinociception in male compared to female rats
    • Boyer J.S., Morgan M.M., and Craft R.M. Microinjection of morphine into the rostral ventromedial medulla produces greater antinociception in male compared to female rats. Brain Res 796 (1998) 315-318
    • (1998) Brain Res , vol.796 , pp. 315-318
    • Boyer, J.S.1    Morgan, M.M.2    Craft, R.M.3
  • 18
    • 0031882905 scopus 로고    scopus 로고
    • Endogenous opioid peptides acting at mu opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons
    • Budai D., and Fields H.L. Endogenous opioid peptides acting at mu opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons. J Neurophysiol 79 (1998) 677-687
    • (1998) J Neurophysiol , vol.79 , pp. 677-687
    • Budai, D.1    Fields, H.L.2
  • 19
    • 0037096409 scopus 로고    scopus 로고
    • Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain
    • Burgess S.E., Gardell L.R., Ossipov M.H., Malan Jr. T.P., Vanderah T.W., Lai J., and Porreca F. Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain. J Neurosci 22 (2002) 5129-5136
    • (2002) J Neurosci , vol.22 , pp. 5129-5136
    • Burgess, S.E.1    Gardell, L.R.2    Ossipov, M.H.3    Malan Jr., T.P.4    Vanderah, T.W.5    Lai, J.6    Porreca, F.7
  • 20
    • 26844546393 scopus 로고    scopus 로고
    • Organizational manipulation of gonadal hormones and systemic morphine analgesia in female rats: effects of adult ovariectomy and estradiol replacement
    • Cataldo G., Bernal S., Markowitz A., Ogawa S., Ragnauth A., Pfaff D.W., and Bodnar R.J. Organizational manipulation of gonadal hormones and systemic morphine analgesia in female rats: effects of adult ovariectomy and estradiol replacement. Brain Res 1059 (2005) 13-19
    • (2005) Brain Res , vol.1059 , pp. 13-19
    • Cataldo, G.1    Bernal, S.2    Markowitz, A.3    Ogawa, S.4    Ragnauth, A.5    Pfaff, D.W.6    Bodnar, R.J.7
  • 21
    • 0028037795 scopus 로고
    • Hyperpolarization by opioids acting on mu-receptors of a sub-population of rat periaqueductal gray neurones in vitro
    • Chieng B., and Christie M.J. Hyperpolarization by opioids acting on mu-receptors of a sub-population of rat periaqueductal gray neurones in vitro. Br J Pharmacol 113 (1994) 121-128
    • (1994) Br J Pharmacol , vol.113 , pp. 121-128
    • Chieng, B.1    Christie, M.J.2
  • 22
    • 0030802504 scopus 로고    scopus 로고
    • Sex-related differences in morphine's antinociceptive activity: relationship to serum and brain morphine concentrations
    • Cicero T.J., Nock B., and Meyer E.R. Sex-related differences in morphine's antinociceptive activity: relationship to serum and brain morphine concentrations. J Pharmacol Exp Ther 282 (1997) 939-944
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 939-944
    • Cicero, T.J.1    Nock, B.2    Meyer, E.R.3
  • 23
    • 0036151732 scopus 로고    scopus 로고
    • Role of steroids in sex differences in morphine-induced analgesia: activational and organizational effects
    • Cicero T.J., Nock B., O'Connor L., and Meyer E.R. Role of steroids in sex differences in morphine-induced analgesia: activational and organizational effects. J Pharmacol Exp Ther 300 (2002) 695-701
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 695-701
    • Cicero, T.J.1    Nock, B.2    O'Connor, L.3    Meyer, E.R.4
  • 24
    • 0034678918 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic relations of mu-opioid receptors to gamma-aminobutyric acid-immunoreactive and medullary-projecting periaqueductal gray neurons
    • Commons K.G., Aicher S.A., Kow L.M., and Pfaff D.W. Presynaptic and postsynaptic relations of mu-opioid receptors to gamma-aminobutyric acid-immunoreactive and medullary-projecting periaqueductal gray neurons. J Comp Neurol 419 (2000) 532-542
    • (2000) J Comp Neurol , vol.419 , pp. 532-542
    • Commons, K.G.1    Aicher, S.A.2    Kow, L.M.3    Pfaff, D.W.4
  • 25
    • 0033553834 scopus 로고    scopus 로고
    • Frequent colocalization of mu opioid and NMDA-type glutamate receptors at postsynaptic sites in periaqueductal gray neurons
    • Commons K.G., van Bockstaele E.J., and Pfaff D.W. Frequent colocalization of mu opioid and NMDA-type glutamate receptors at postsynaptic sites in periaqueductal gray neurons. J Comp Neurol 408 (1999) 549-559
    • (1999) J Comp Neurol , vol.408 , pp. 549-559
    • Commons, K.G.1    van Bockstaele, E.J.2    Pfaff, D.W.3
  • 26
    • 15744366900 scopus 로고    scopus 로고
    • Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats
    • Cook C.D., and Nickerson M.D. Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats. J Pharmacol Exp Ther 313 (2005) 449-459
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 449-459
    • Cook, C.D.1    Nickerson, M.D.2
  • 27
    • 0037414402 scopus 로고    scopus 로고
    • Sex differences in drug- and non-drug-induced analgesia
    • Craft R.M. Sex differences in drug- and non-drug-induced analgesia. Life Sci 72 (2003) 2675-2688
    • (2003) Life Sci , vol.72 , pp. 2675-2688
    • Craft, R.M.1
  • 28
    • 0038662987 scopus 로고    scopus 로고
    • Sex differences in opioid analgesia: "from mouse to man"
    • Craft R.M. Sex differences in opioid analgesia: "from mouse to man". Clin J Pain 19 (2003) 175-186
    • (2003) Clin J Pain , vol.19 , pp. 175-186
    • Craft, R.M.1
  • 29
    • 0032525247 scopus 로고    scopus 로고
    • Estrogen-induced alteration of mu-opioid receptor immunoreactivity in the medial preoptic nucleus and medial amygdala
    • Eckersell C.B., Popper P., and Micevych P.E. Estrogen-induced alteration of mu-opioid receptor immunoreactivity in the medial preoptic nucleus and medial amygdala. J Neurosci 18 (1998) 3967-3976
    • (1998) J Neurosci , vol.18 , pp. 3967-3976
    • Eckersell, C.B.1    Popper, P.2    Micevych, P.E.3
  • 30
    • 0022633687 scopus 로고
    • Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription
    • Greenberg M.E., Hermanowski A.L., and Ziff E.B. Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription. Mol Cell Biol 6 (1986) 1050-1057
    • (1986) Mol Cell Biol , vol.6 , pp. 1050-1057
    • Greenberg, M.E.1    Hermanowski, A.L.2    Ziff, E.B.3
  • 31
    • 0023034795 scopus 로고
    • Stimulation of neuronal acetylcholine receptors induces rapid gene transcription
    • Greenberg M.E., Ziff E.B., and Greene L.A. Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science 234 (1986) 80-83
    • (1986) Science , vol.234 , pp. 80-83
    • Greenberg, M.E.1    Ziff, E.B.2    Greene, L.A.3
  • 32
    • 0036156527 scopus 로고    scopus 로고
    • Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation
    • Guan Y., Terayama R., Dubner R., and Ren K. Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation. J Pharmacol Exp Ther 300 (2002) 513-520
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 513-520
    • Guan, Y.1    Terayama, R.2    Dubner, R.3    Ren, K.4
  • 33
    • 14044278005 scopus 로고    scopus 로고
    • Characterization of morphine-induced hyperalgesia in male and female rats
    • Holtman Jr. J.R., and Wala E.P. Characterization of morphine-induced hyperalgesia in male and female rats. Pain 114 (2005) 62-70
    • (2005) Pain , vol.114 , pp. 62-70
    • Holtman Jr., J.R.1    Wala, E.P.2
  • 34
    • 33745825500 scopus 로고    scopus 로고
    • Sex differences in morphine-induced analgesia of visceral pain are supraspinally and peripherally mediated
    • Ji Y., Murphy A.Z., and Traub R.J. Sex differences in morphine-induced analgesia of visceral pain are supraspinally and peripherally mediated. Am J Physiol Regul Integr Comp Physiol 291 (2006) R307-R314
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • Ji, Y.1    Murphy, A.Z.2    Traub, R.J.3
  • 35
    • 34250196595 scopus 로고    scopus 로고
    • Ji Y, Murphy AZ, Traub RJ. Estrogen modulation of morphine analgesia of visceral pain in female rats is supraspinally and peripherally mediated. J Pain, in press.
  • 36
    • 1342309260 scopus 로고    scopus 로고
    • Estrogen modulation of G-protein-coupled receptor activation of potassium channels in the central nervous system
    • Kelly M.J., Qiu J., and Ronnekleiv O.K. Estrogen modulation of G-protein-coupled receptor activation of potassium channels in the central nervous system. Ann N Y Acad Sci 1007 (2003) 6-16
    • (2003) Ann N Y Acad Sci , vol.1007 , pp. 6-16
    • Kelly, M.J.1    Qiu, J.2    Ronnekleiv, O.K.3
  • 37
    • 0033032192 scopus 로고    scopus 로고
    • Sex differences in supraspinal morphine analgesia are dependent on genotype
    • Kest B., Wilson S.G., and Mogil J.S. Sex differences in supraspinal morphine analgesia are dependent on genotype. J Pharmacol Exp Ther 289 (1999) 1370-1375
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 1370-1375
    • Kest, B.1    Wilson, S.G.2    Mogil, J.S.3
  • 38
    • 0033528449 scopus 로고    scopus 로고
    • Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats
    • Krzanowska E.K., and Bodnar R.J. Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats. Brain Res 821 (1999) 224-230
    • (1999) Brain Res , vol.821 , pp. 224-230
    • Krzanowska, E.K.1    Bodnar, R.J.2
  • 39
    • 24044529819 scopus 로고    scopus 로고
    • Evidence for an intrinsic mechanism of antinociceptive tolerance within the ventrolateral periaqueductal gray of rats
    • Lane D.A., Patel P.A., and Morgan M.M. Evidence for an intrinsic mechanism of antinociceptive tolerance within the ventrolateral periaqueductal gray of rats. Neuroscience 135 (2005) 227-234
    • (2005) Neuroscience , vol.135 , pp. 227-234
    • Lane, D.A.1    Patel, P.A.2    Morgan, M.M.3
  • 41
    • 0033039834 scopus 로고    scopus 로고
    • Neurones in the dorsolateral periaqueductal grey matter in coronal slices of rat midbrain: electrophysiological and morphological characteristics
    • Lovick T.A., and Stezhka V.V. Neurones in the dorsolateral periaqueductal grey matter in coronal slices of rat midbrain: electrophysiological and morphological characteristics. Exp Brain Res 124 (1999) 53-58
    • (1999) Exp Brain Res , vol.124 , pp. 53-58
    • Lovick, T.A.1    Stezhka, V.V.2
  • 42
    • 34250195485 scopus 로고    scopus 로고
    • Loyd D, Murphy A. Selective lesions of the mu opioid receptor in the periaqueductal gray significantly attenuates systemic morphine analgesia in male rats. Soc Neurosci Abstr, in press.
  • 43
    • 33645985808 scopus 로고    scopus 로고
    • Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: a potential circuit mediating the sexually dimorphic actions of morphine
    • Loyd D.R., and Murphy A.Z. Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: a potential circuit mediating the sexually dimorphic actions of morphine. J Comp Neurol 496 (2006) 723-738
    • (2006) J Comp Neurol , vol.496 , pp. 723-738
    • Loyd, D.R.1    Murphy, A.Z.2
  • 44
    • 33745828085 scopus 로고    scopus 로고
    • Identification of neural circuits involved in female genital responses in the rat: a dual virus and anterograde tracing study
    • Marson L., and Murphy A.Z. Identification of neural circuits involved in female genital responses in the rat: a dual virus and anterograde tracing study. Am J Physiol Regul Integr Comp Physiol 291 (2006) R419-R428
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • Marson, L.1    Murphy, A.Z.2
  • 45
    • 0345701341 scopus 로고    scopus 로고
    • Estrogen receptor-alpha is required for estrogen-induced mu-opioid receptor internalization
    • Micevych P.E., Rissman E.F., Gustafsson J.A., and Sinchak K. Estrogen receptor-alpha is required for estrogen-induced mu-opioid receptor internalization. J Neurosci Res 71 (2003) 802-810
    • (2003) J Neurosci Res , vol.71 , pp. 802-810
    • Micevych, P.E.1    Rissman, E.F.2    Gustafsson, J.A.3    Sinchak, K.4
  • 46
    • 0742270489 scopus 로고    scopus 로고
    • Estrogen-induced mu-opioid receptor internalization in the medial preoptic nucleus is mediated via neuropeptide Y-Y1 receptor activation in the arcuate nucleus of female rats
    • Mills R.H., Sohn R.K., and Micevych P.E. Estrogen-induced mu-opioid receptor internalization in the medial preoptic nucleus is mediated via neuropeptide Y-Y1 receptor activation in the arcuate nucleus of female rats. J Neurosci 24 (2004) 947-955
    • (2004) J Neurosci , vol.24 , pp. 947-955
    • Mills, R.H.1    Sohn, R.K.2    Micevych, P.E.3
  • 47
    • 0023035577 scopus 로고
    • Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission
    • Moreau J.L., and Fields H.L. Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission. Brain Res 397 (1986) 37-46
    • (1986) Brain Res , vol.397 , pp. 37-46
    • Moreau, J.L.1    Fields, H.L.2
  • 48
    • 0029162079 scopus 로고
    • Fos expression induced by changes in arterial pressure is localized in distinct, longitudinally organized columns of neurons in the rat midbrain periaqueductal gray
    • Murphy A.Z., Ennis M., Rizvi T.A., Behbehani M.M., and Shipley M.T. Fos expression induced by changes in arterial pressure is localized in distinct, longitudinally organized columns of neurons in the rat midbrain periaqueductal gray. J Comp Neurol 360 (1995) 286-300
    • (1995) J Comp Neurol , vol.360 , pp. 286-300
    • Murphy, A.Z.1    Ennis, M.2    Rizvi, T.A.3    Behbehani, M.M.4    Shipley, M.T.5
  • 49
    • 0032837239 scopus 로고    scopus 로고
    • Distribution of androgen and estrogen receptor containing neurons in the male rat periaqueductal gray
    • Murphy A.Z., and Hoffman G.E. Distribution of androgen and estrogen receptor containing neurons in the male rat periaqueductal gray. Horm Behav 36 (1999) 98-108
    • (1999) Horm Behav , vol.36 , pp. 98-108
    • Murphy, A.Z.1    Hoffman, G.E.2
  • 50
    • 0035903982 scopus 로고    scopus 로고
    • Distribution of gonadal steroid receptor-containing neurons in the preoptic-periaqueductal gray-brainstem pathway: A potential circuit for the initiation of male sexual behavior
    • Murphy A.Z., and Hoffman G.E. Distribution of gonadal steroid receptor-containing neurons in the preoptic-periaqueductal gray-brainstem pathway: A potential circuit for the initiation of male sexual behavior. J Comp Neurol 438 (2001) 191-212
    • (2001) J Comp Neurol , vol.438 , pp. 191-212
    • Murphy, A.Z.1    Hoffman, G.E.2
  • 51
    • 0032774747 scopus 로고    scopus 로고
    • Opioid antinociception in ovariectomized monkeys: comparison with antinociception in males and effects of estradiol replacement
    • Negus S.S., and Mello N.K. Opioid antinociception in ovariectomized monkeys: comparison with antinociception in males and effects of estradiol replacement. J Pharmacol Exp Ther 290 (1999) 1132-1140
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1132-1140
    • Negus, S.S.1    Mello, N.K.2
  • 52
    • 14044253365 scopus 로고    scopus 로고
    • Differential modulation of TMJ neurons in superficial laminae of trigeminal subnucleus caudalis/upper cervical cord junction region of male and cycling female rats by morphine
    • Okamoto K., Tashiro A., Hirata H., and Bereiter D.A. Differential modulation of TMJ neurons in superficial laminae of trigeminal subnucleus caudalis/upper cervical cord junction region of male and cycling female rats by morphine. Pain 114 (2005) 203-211
    • (2005) Pain , vol.114 , pp. 203-211
    • Okamoto, K.1    Tashiro, A.2    Hirata, H.3    Bereiter, D.A.4
  • 53
    • 0030054174 scopus 로고    scopus 로고
    • Opioid inhibition of rat periaqueductal grey neurones with identified projections to the rostral ventromedial medulla in vitro
    • Osborne P.B., Vaughan C.W., Wilson H.I., and Christie M.J. Opioid inhibition of rat periaqueductal grey neurones with identified projections to the rostral ventromedial medulla in vitro. J Physiol (Lond) 490 (1996) 383-389
    • (1996) J Physiol (Lond) , vol.490 , pp. 383-389
    • Osborne, P.B.1    Vaughan, C.W.2    Wilson, H.I.3    Christie, M.J.4
  • 55
    • 0026489419 scopus 로고
    • Intravenous morphine-induced activation of vagal afferents: peripheral, spinal, and CNS substrates mediating inhibition of spinal nociception and cardiovascular responses
    • Randich A., Thurston C., Ludwig P., Robertson J., and Tasmussen C. Intravenous morphine-induced activation of vagal afferents: peripheral, spinal, and CNS substrates mediating inhibition of spinal nociception and cardiovascular responses. J Neurophysiol 68 (1992) 1027-1045
    • (1992) J Neurophysiol , vol.68 , pp. 1027-1045
    • Randich, A.1    Thurston, C.2    Ludwig, P.3    Robertson, J.4    Tasmussen, C.5
  • 56
    • 0030058822 scopus 로고    scopus 로고
    • Medial preoptic area afferents to periaqueductal gray medullo-output neurons: A combined Fos and tract tracing study
    • Rizvi T.A., Murphy A.Z., Ennis M., Behbehani M.M., and Shipley M.T. Medial preoptic area afferents to periaqueductal gray medullo-output neurons: A combined Fos and tract tracing study. J Neurosci 16 (1996) 333-344
    • (1996) J Neurosci , vol.16 , pp. 333-344
    • Rizvi, T.A.1    Murphy, A.Z.2    Ennis, M.3    Behbehani, M.M.4    Shipley, M.T.5
  • 57
    • 0035425622 scopus 로고    scopus 로고
    • Progesterone blockade of estrogen activation of mu-opioid receptors regulates reproductive behavior
    • Sinchak K., and Micevych P.E. Progesterone blockade of estrogen activation of mu-opioid receptors regulates reproductive behavior. J Neurosci 21 (2001) 5723-5729
    • (2001) J Neurosci , vol.21 , pp. 5723-5729
    • Sinchak, K.1    Micevych, P.E.2
  • 58
    • 0028803461 scopus 로고
    • Repeated spinal cord stimulation decreases the extracellular level of gamma-aminobutyric acid in the periaqueductal gray matter of freely moving rats
    • Stiller C.O., Linderoth B., O'Connor W.T., Franck J., Falkenberg T., Ungerstedt U., and Brodin E. Repeated spinal cord stimulation decreases the extracellular level of gamma-aminobutyric acid in the periaqueductal gray matter of freely moving rats. Brain Res 699 (1995) 231-241
    • (1995) Brain Res , vol.699 , pp. 231-241
    • Stiller, C.O.1    Linderoth, B.2    O'Connor, W.T.3    Franck, J.4    Falkenberg, T.5    Ungerstedt, U.6    Brodin, E.7
  • 59
    • 16844384439 scopus 로고    scopus 로고
    • Gonadal hormone modulation of mu, kappa, and delta opioid antinociception in male and female rats
    • Stoffel E.C., Ulibarri C.M., Folk J.E., Rice K.C., and Craft R.M. Gonadal hormone modulation of mu, kappa, and delta opioid antinociception in male and female rats. J Pain 6 (2005) 261-274
    • (2005) J Pain , vol.6 , pp. 261-274
    • Stoffel, E.C.1    Ulibarri, C.M.2    Folk, J.E.3    Rice, K.C.4    Craft, R.M.5
  • 60
    • 0034717563 scopus 로고    scopus 로고
    • Activity-induced plasticity in brain stem pain modulatory circuitry after inflammation
    • Terayama R., Guan Y., Dubner R., and Ren K. Activity-induced plasticity in brain stem pain modulatory circuitry after inflammation. Neuroreport 11 (2000) 1915-1919
    • (2000) Neuroreport , vol.11 , pp. 1915-1919
    • Terayama, R.1    Guan, Y.2    Dubner, R.3    Ren, K.4
  • 61
    • 0025880190 scopus 로고
    • Subregions of the periaqueductal gray topographically innervate the rostral ventral medulla in the rat
    • van Bockstaele E.J., Aston-Jones G., Pieribone V.A., Ennis M., and Shipley M.T. Subregions of the periaqueductal gray topographically innervate the rostral ventral medulla in the rat. J Comp Neurol 309 (1991) 305-327
    • (1991) J Comp Neurol , vol.309 , pp. 305-327
    • van Bockstaele, E.J.1    Aston-Jones, G.2    Pieribone, V.A.3    Ennis, M.4    Shipley, M.T.5
  • 62
    • 0035141560 scopus 로고    scopus 로고
    • Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance
    • Vanderah T.W., Suenaga N.M., Ossipov M.H., Malan Jr. T.P., Lai J., and Porreca F. Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. J Neurosci 21 (2001) 279-286
    • (2001) J Neurosci , vol.21 , pp. 279-286
    • Vanderah, T.W.1    Suenaga, N.M.2    Ossipov, M.H.3    Malan Jr., T.P.4    Lai, J.5    Porreca, F.6
  • 63
    • 0031033471 scopus 로고    scopus 로고
    • Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro
    • Vaughan C.W., and Christie M.J. Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro. J Physiol 498 (1997) 463-472
    • (1997) J Physiol , vol.498 , pp. 463-472
    • Vaughan, C.W.1    Christie, M.J.2
  • 64
    • 33744518427 scopus 로고    scopus 로고
    • Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis
    • Vera-Portocarrero L.P., Xie J.Y., Kowal J., Ossipov M.H., King T., and Porreca F. Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis. Gastroenterology 130 (2006) 2155-2164
    • (2006) Gastroenterology , vol.130 , pp. 2155-2164
    • Vera-Portocarrero, L.P.1    Xie, J.Y.2    Kowal, J.3    Ossipov, M.H.4    King, T.5    Porreca, F.6
  • 65
    • 33745267063 scopus 로고    scopus 로고
    • Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization
    • Vera-Portocarrero L.P., Zhang E.T., Ossipov M.H., Xie J.Y., King T., Lai J., and Porreca F. Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization. Neuroscience 140 (2006) 1311-1320
    • (2006) Neuroscience , vol.140 , pp. 1311-1320
    • Vera-Portocarrero, L.P.1    Zhang, E.T.2    Ossipov, M.H.3    Xie, J.Y.4    King, T.5    Lai, J.6    Porreca, F.7
  • 66
    • 0037074884 scopus 로고    scopus 로고
    • Mu- and delta-opioid receptor mRNAs are expressed in periaqueductal gray neurons projecting to the rostral ventromedial medulla
    • Wang H., and Wessendorf M.W. Mu- and delta-opioid receptor mRNAs are expressed in periaqueductal gray neurons projecting to the rostral ventromedial medulla. Neuroscience 109 (2002) 619-634
    • (2002) Neuroscience , vol.109 , pp. 619-634
    • Wang, H.1    Wessendorf, M.W.2
  • 67
    • 0038743150 scopus 로고    scopus 로고
    • The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity
    • Wang L.H., Yang X.Y., Zhang X., Mihalic K., Xiao W., and Farrar W.L. The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity. Cancer Res 63 (2003) 2046-2051
    • (2003) Cancer Res , vol.63 , pp. 2046-2051
    • Wang, L.H.1    Yang, X.Y.2    Zhang, X.3    Mihalic, K.4    Xiao, W.5    Farrar, W.L.6
  • 69
    • 0022458884 scopus 로고
    • Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology
    • Watson R.E., Wiegand S.J., Clough R.W., and Hoffman G.E. Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides 7 (1986) 155-159
    • (1986) Peptides , vol.7 , pp. 155-159
    • Watson, R.E.1    Wiegand, S.J.2    Clough, R.W.3    Hoffman, G.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.