Differential expression of desmosomal glycoproteins in keratoacanthoma and squamous cell carcinoma of the skin: An immunohistochemical aid to diagnosis

Acta Dermato-Venereologica

Volumn 76, Issue 5, 1996, Pages 394-398

  Krunic, A L J ^a   Garrod, D R ^b   Smith, Neil P ^c   Orchard, G S ^c   Cvijetic, O B ^d  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c ST THOMAS HOSPITAL   (United Kingdom)

^d UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN;

ARTICLE; CONTROLLED STUDY; DESMOSOME; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATOACANTHOMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

EID: 0029824402     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Schwartz RA. Keratoacanthoma. J Am Acad Dermatol 1994; 30: 1-19.
2. Fisher ER, McCoy MM, Wechsler HL. Analysis of histopathologic and electron microscopic determinants of keratoacanthoma and squamous cell carcinoma. Cancer 1972; 29: 1387 1397.
3. Janecka IP, Wolff M, Crikelair GF, Cosman B. Aggressive histological features of keratoacanthoma. J Cutan Pathol 1978; 4: 342-348.
4. Schaumburg-Lever G, Alroy J, Gavris V, Ucci A, Lever WF. Cell surface carbohydrates in proliferative epidermal lesions. Distribution of A, B, and H blood group antigens in benign and malignant lesions. Am J Dermatopathol 1984; 6: 583 589.
5. Ariano MC, Wiley EL, Ariano L, Coon JS, Tetzlaff L. H, Peanut lectin receptor, and carcinoembryonic antigen distribution in keratoacanthomas, squamous dysplasias, and carcinomas of the skin. J Dermatol Surg Oncol 1985; 11: 1076-1083.
6. Markey AC, Churchill LJ, Mac Donald DM. Altered expression of major histocompatibility complex (MHC) antigens by epidermal tumours. J Cutan Pathol 1990; 17: 65-71.
7. De Morgas JM, Winkelmann RK, Jordan RE. Immunofluorescence of epithelial skin tumors. I. Patterns of intracellular substance. Cancer 1970; 25: 1399-1403.
8. Kanitakis J, Hoyo E, Hermier C, Chouvet B, Thivolet J. Nucleolar organizer region enumeration in keratoacanthomas and squamous cell carcinomas of the skin. Cancer 1992; 69: 2937-2941.
9. Smoller BR, Kwan TH, Said JW, Banks-Schlegel S. Keratoacanthoma and squamous cell carcinoma of the skin; immunohistochemical localization of involucrin and keratin proteins. J Am Acad Dermatol 1986; 14: 226-234.
10. Klein-Szanto AJP, Barr RJ, Reiners JJ, Mamrack MD. Filaggrin distribution in keratoacanthoma and squamous cell carcinoma. Arch Pathol Lab Med 1984; 108: 888-890.
11. Graham RM, Macfarlane AW, Curley RK, Nash JRG: Beta 2 microglobulin expression in keratoacanthoma and squamous cell carcinoma. Br J Dermatol 1987; 117: 441-449.
12. McNutt NS, Saenz-Santamaria C, Volkenandt M, Shea CR, Albino AP. Abnormalities of p53 protein expression in cutaneous disorders. Arch Dermatol 1994; 130: 225 232.
13. Hodak E, Jones RE, Ackerman BA. Solitary keratoacanthoma is a squamous cell carcinoma: three examples with metastases. Am J Dermatopathol 1993; 15: 332-352.
14. Sina B. The spectrum of cutaneous pseudomalignancy. Cutis 1984; 34: 381 384.
15. Kingman J, Callen JP. Keratoacanthoma a clinical study. Arch Dermatol 1984; 120: 736 740.
16. Slaga TJ. Cellular and molecular mechanisms involved in multistage skin carcinogenesis. In: Conti CJ, Slaga TJ, Klein-Szanto AJP, eds. "Skin tumors": "experimental and clinical aspects". New York: Raven Press, 1989: 1 18.
17. Miracco CC, De Santi MM, Lio R, Biagioli P, Tosi P, Luzi P. Quantitatively evaluated ultrastructural findings can add to the differential diagnosis between keratoacanthoma and well differentiated squamous cell carcinoma. J Submycrose Cytol Pathol 1992; 24: 315 321.
18. Muller HK, Flannery GR. Epidermal antigens in experimental keratoacanthoma and squamous cell carcinoma. Cancer Res 1973; 33: 2181 2186.
19. Olague-Alcala M, Giudice GJ, Diaz AL. Pemphigus foliaceous sera recognize an N-terminal fragment of bovine desmoglein 1. J Invest Dermatol 1994; 102: 882 885.
20. Amagai M, Kàrpàti S, Klaus-Kovtun V, Udey MC, Stanley JR. Extracellular domain of pemphigus vulgaris antigen (Desmoglein 3) mediates weak homophilic adhesion. J Invest Dermatol 1994; 102: 402-408.
21. Garrod DR. Desmosomes and hemidesmosomes. Curr Opin Cell Biol 1993; 5: 30 40.
22. Vilela MJ, Parish EP, Wright DH, Garrod DR. Monoclonal antibody to desmosomal glycoprotein 1 a new epithelial marker for diagnostic pathology. J Pathol 1987; 153: 365 375.
23. Dmochowski M, Hashimoto T, Amagai M, Kudoh J, Shimizu N, Koch PJ, et al. The extracellular aminoterminal domain of bovine desmoglein (Dsg 1) is recognised only by certain pemphigus foliaceus sera, whereas its intracellular domain is recognized by both pemphigus vulgaris and pemphigus foliaceus sera. J Invest Dermatol 1994; 103: 173 177.
24. Vilela MJ, Hashimoto T, Nishikawa T. A simple epithelial cell line (MDCK) shows heterogeneity of desmoglein isoforms. one resembling pemphigus vulgaris antigen. (1995, submitted to J Cell Sci.)
25. Hsu SM, Raine L, Fanger H. The use of antiavidin antibody and avidin-biotin-peroxidase complex in immunoperoxidase technics. Am J Clin Pathol 1981; 76: 816 821.
26. Broders AC. Squamous cell epithelioma of the skin. Ann Surg 1925; 73: 141 160.
27. Wick MR. Malignant tumors of the epidermis. In: Farmer ER, Hood AF, eds. Pathology of the skin. Norwalk, Connecticut: Appleton Lange, 1990: 568-595.
28. Harada T, Shinohara M, Nakamura S, Shimada M, Oka M. Immunohistochemical detection of desmosomes in oral squamous cell carcinomas: correlation with differentiation, mode of invasion, and metastatic potential. Int J Oral Maxillofac Surg 1992; 21: 346 349.
29. Conn IG, Vilela MJ, Garrod DR, Crocker J, Wallace DM. Immunohistochemical staining with monoclonal antibody 32-2B to desmosomal glycoprotein 1: its role in histological assesment of urothelial tumours. Br J Urol 1990; 65: 176 180.
30. Ghadially FN. Diagnostic electron microscopy of tumours. London: Butterworths, 1980.
31. Piscioli F, Boi S, Zumiani G, Cristofolini M. A gigantic metastasizing keratocanthoma. Am J Dermatopathol 1984; 6: 123-129.
32. Sleater JP, Beers BB, Stephens C, Hendricks JB. Keratoacanthoma: a deficient squamous cell carcinoma? Study of bcl-2 expression. J Cutan Pathol 1994; 21: 514-519.
33. Lu QL, Poulsom R, Wong L, Hanby AM. Bcl-2 expression in adult and embryonic non-haematopoietic tissues. J Pathol 1993; 169: 431-437.