Polyunsaturated fatty acids (PUFAs) content of the fungus Mortierella alpina isolated from soil

Journal of Agricultural and Food Chemistry

Volumn 55, Issue 10, 2007, Pages 3960-3966

  Ho, Sze Yuen ^a   Jiang, Yue ^b   Chen, Feng ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Heterotrophic; Mortierella alpina; Polyunsaturated fatty acids (PUFAs); Soil fungus

Indexed keywords

UNSATURATED FATTY ACID;

CHEMISTRY; CONFERENCE PAPER; FERMENTATION; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; MICROBIOLOGY; MORTIERELLA;

FATTY ACIDS, UNSATURATED; FERMENTATION; MORTIERELLA; SOIL MICROBIOLOGY;

FUNGI; MORTIERELLA; MORTIERELLA ALPINA;

EID: 34249875737     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf0700071     Document Type: Conference Paper

References (33)

1. Certik, M.; Shimizu, S. Biosynthesis and regulation of microbial polyunsaturated fatty acid production. J. Biosci. Bioeng. 1999, 87 (1), 1-14.
2. Innis, S. M. Essential fatty acids in growth and development. Prog. Lipid Res. 1991, 30, 39-103.
3. Suresh, Y.; Das, U. N. Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus. Prostaglandins, Leukotrienes Essent. 2006, 74, 199-213.
4. Gill, I.; Valivety, R. Polyunsaturated fatty acids, part 1: Occurrence, biological activities and applications. Trends Biotechnol. 1997, 15, 401-409.
5. Ward, O. P.; Singh, A. Omega-3/6 fatty acids: alternative sources of production. Process Biochem. 2005, 40, 3627-3652.
6. Suresh, Y.; Das, U. N. Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus: effect of ω-6 fatty acids. Nutrition 2003, 19, 93-114.
7. Ratledge, C. Fatty acid biosynthesis in microorganisms being used for single cell oil production. Biochimie 2004, 86, 807-815.
8. Higashiyama, K.; Fujikawa, S.; Park, E. Y.; Shimizu, S. Production of arachidonic acid by Mortierella fungi. Biotechnol. Bioprocess Eng. 2002, 7, 252-262.
9. Shinmen, Y.; Shimizu, S.; Akimoto, K.; Kawashima, H.; Yamada, H. Production of arachidonic acid by Mortierella fungi: selection of a potent producer and optimization of culture for large-scale production. Appl. Microbiol. Biotechnol. 1989, 31, 11-16.
10. Bajpai, P. K.; Bajpai, P.; Ward, O. P. Production of arachidonic acid by Mortierella alpina ATCC 32222. J. Ind. Microbiol. 1991, 8, 179-186.
11. Jang, H.-D.; Lin, Y.-Y.; Yang, S.-S. Effect of culture media and conditions on polyunsaturated fatty acids production by Mortierella alpina. Bioresour. Technol. 2005, 96, 1633-1644.
12. Shinmen, Y.; Kawashima, H.; Shimizu, S.; Yamada, H. Concentration of eciosapentaenoic acid and docosahexaenoic acid in an arachidonic acid-producing fungus, Mortierella alpina 1S-4, grown with fish oil. Appl. Microbiol. Biotechnol. 1992, 38, 301-304.
13. Warcup, J. H. The soil-plate method for isolation of fungi from soil. Nature 1950, 166, 117-118.
14. Botha, A.; Paul, I.; Roux, C.; Kock, J. L. F.; Coetzee, D. J.; Strauss, T.; Maree, C. An isolation procedure for arachidonic acid producing Mortierella species. Antonie Leeuwenhoek 1999, 75, 253-256.
15. Gams, W. A key to the species of Mortierella. Persoonia 1977, 9, 381-391.
16. Domsch, K. H.; Gams, W.; Anderson, T.-H. Compendium of Soil Fungi; Academic Press: London, U.K., 1980; Vol. 1.
17. Miller, G. L. Use of dinitrosalicyclic acid reagent for determination of reducing sugar. Anal. Chem. 1959, 31, 426-429.
18. Lewis, T. E.; Nichols, P. D.; McMeekin, T. A. Sterol and squalene content of docosahexaenoic-acid-producing thraustrochytrid: influence of culture age, temperature, and dissolved oxygen. Mar. Biotechnol. 2001, 3, 439-447.
19. Lee, S. B.; Taylor, J. W. Isolation of DNA from fungal mycelia and single spores. In PCR Protocols: A Guide to Methods and Applications; Innis, M. A., Gelfand, D. H., Sninsky, J. J., White, T. J., Eds.; Academic Press: San Diego, CA, 1990; pp 282-287.
20. White, T. J.; Bruns, T.; Lee, S.; Taylor, J. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. In PCR Protocols: A Guide to Methods and Applications; Innis, M. A., Gelfand, D. H., Sninsky, J. J., White, T. J., Eds.; Academic Press: San Diego, CA, 1990; pp 315-322.
21. Thompson, J. D.; Gibson, T. J.; Plewniak, F.; Jeanmougin, F.; Higgins, D. G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tool. Nucleic Acids Res. 1997, 25, 4876-4882.
22. Chen, F.; Johns, M. R. Effect of C/N ratio and aeration on the fatty acid composition of heterotrophic Chlorella sorokiniana. J. Appl. Phycol. 1991, 3, 203-209.
23. Berry, E. M.; Eisenberg, S.; Haratz, D.; Friedlander, Y.; Norman, Y.; Kaufmann, N. A.; Stein, Y. Effects of diet rich in monounsaturated fatty acids on plasma lipoproteins - the Jerusalem nutrition study: high MUFAs vs high PUFAs. Am. J. Clin. Nutr. 1991, 53, 899-907.
24. Streekstra, H. On the safety of Mortierella alpina for the production of food ingredients, such as arachidonic acid. J. Biotechnol. 1997, 56, 153-165.
25. Hempenius, R. A.; van Delft, J. M. H.; Prinsen, M.; Lina, B. A. R. Preliminary safety assessment of an arachidonic acid-enriched oil derived from Mortierella alpina: summary of toxicological data. Food Chem. Toxicol. 1997, 35, 573-581.
26. Hempenius, R. A.; Lina, B. A. R.; Haggit, R. C. Evaluation of a sub-chronic (13-week) oral toxicity study, preceded by an in utero exposure phase, with arachidonic acid oil derived from Mortierella alpina in rats. Food Chem. Toxicol. 2000, 38, 127-139.
27. Carter, A. T.; Mackenzie, D. A.; Pearson, B. M.; Archer, D. B. PCR fingerprinting with a consensus tRNA primer enables strain identification of Mortierella alpina. Mycol. Res. 2000, 104, 794-799.
28. Kwasna, H.; Ward, E.; Bateman, G. L. Phylogenetic relationships among Zygomycetes from soil based on ITS1/2 rDNA sequences. Mycol. Res. 2006, 110, 501-510.
29. Zhu, M.; Yu, L.-J.; Li, W.; Zhou, P.-P.; Li, C.-Y. Optimization of arachidonic acid production by fed-batch culture of Mortierella alpina based on dynamic analysis. Enzyme Microb. Technol. 2006, 38, 735-740.
30. Wynn, J. P.; Hamid, A. A.; Li, Y.; Ratledge, C. Biochemical events leading to the diversion of carbon into storage lipids in the oleaginous fungi Mucor circinelloides and Mortierella alpina. Microbiology 2001, 147, 2857-2864.
31. Singh, A.; Ward, O. P. Production of high yields of arachidonic acid in a fed-batch system by Mortierella alpina ATCC32222. Appl. Microbiol. Biot. 1997, 48, 1-5.
32. Certik, M.; Shimizu, S. Isolation and lipid analyses of subcellular fractions from the arachidonic acid producing fungus Mortierella alpina 1S-4. Biologia 2003, 58, 1101-1110.
33. Jiang, Y.; Fan, K.-W.; Wong, R. T.-Y.; Chen, F. Fatty acid composition and squalene content of marine microalga Schizochytrium mangrovei. J. Agric. Food Chem. 2004, 52, 1196-1200.