Calcium homeostasis deregulation in glutamate-induced excitotoxicity and its role in neurodegenerative diseases

Chinese Pharmacological Bulletin

Volumn 23, Issue 3, 2007, Pages 289-292

  Ren, Zhen Yu ^a   Yu, Xiao Qian ^a   Peng, Shuang Qing ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Calcium; Excitotoxicity; Glutamate; Mitochondrial; Neurodegeneration

Indexed keywords

GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; DEGENERATIVE DISEASE; DRUG MECHANISM; EXCITOTOXICITY; NEUROTOXICITY;

EID: 34249822785     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Hardingham G E, Hilmar B. The Yin and Yang of NMDA receptor Signaling[J]. Trends in Neurosciences,2003,26(2):81-9.
2. Iacopino A, Christakos S, German D, et al. Calbindin-D28K-ontaining neurons in animal models of neurodegeneration: possible protection from excitotoxicity[J]. Mol Brain Res,1992,13(3): 251-61.
3. Luo C, Guo L J. Effect of taurine on acute ischemia - induced neuron apoptosis in rats[J]. Chin Pharmacol Bull,2005,21(9): 1057-61.
4. Choi D W. Ionic dependence of glutamate neurotoxicity in cortical cell culture[J]. Neurosci,1987,7(2):369-79.
5. Khodorov B, Pinelis V, Vergun O, et al. Mitochondrial deenergization underlies neuronal calcium overload following a prolonged glutamate challenge[J]. FEBS Lett,1996,397(2-3):230-4.
6. Reveron M E, Monks T J, Duvauchelle C L. Age-dependent(+) MDMA mediated neurotoxicity in mice[J]. Neuro Toxicol,2005, 26(6):1031-40.
7. Saura C A, Se-Young C, Beglopoulos V. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration[J]. Neuron,2004,42(1): 23-36.
8. Cantuti-Castelvetril I, Shukitt-Hale B, Joseph J A. Dopamine neurotoxicity: age-dependent behavioral and histological effects [J]. Neurobiol Aging,2003,24(5):697-706.
9. Khodorov B I, Storozhevykh T P, Surin A M, et al. The dominant role of mitochondrial depolarization in the mechanism of perturbation calcium homeostasis caused by glutamate[J]. Neuro Behav Physiol,2002,32(5) :541-7.
10. Vergun O, Keelan J, Khodorov B I, Duchen M R. Glutamate-induced mitochondrial depolarization and perturbation of calcium homeostasis in cultured rat hippocampal neurons[J]. Physiol,1999, 519(Part 2):451-66.
11. Canettieri G, Morantte I, Guzman E, et al. Attenuation of a phosphorylationdependent activator by an HDAC-PP1 complex[J]. Nat Struct Biol,2003,10(3):175-81.
12. Carriedo S G, Yin H Z, Weiss J H. Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro[J]. J Neurosci,1996,16(13):4069-79.
13. 2+-permeable AMPA/ kainate channel expression in hippocampal pyramidal neurons: fluorescence imaging and immunocytochemical assessment[J]. J Neurosci,2003, 23(33):10521-30.
14. Hong S J, Dawson T M, Dawson V L. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling[J]. Trends Pharmacol Sci,2004,25(5):259-64.
15. Lee J Y, Kim J H, Palmiter R D, Koh J Y. Zinc released from metallothionein-iii may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury[J]. Exp Neurol, 2003,184(1): 337-47.
16. 2+ accumulation and neuronal loss in hippocampal pyramidal neurons[J]. J Neurosci,2002,22(4):1273-9.
17. Shi S, Hayashi Y, Esteban J A, Malinow R. Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons[J]. Cell,2001,105(3):331-43.
18. Snyder E M, Philpot B D, Huber K M, et al. Internalization of ionotropic glutamate receptors in response to mGluR activation [J]. Nat Neurosci,2001,4(11):1079-85.
19. Choi D W. Glutamate neurotoxicity and diseases of the nervous system[J]. Neuron,1988,1(8):623-63
20. DeLorenzo R J, Suna D A, Deshpandea L S. Cellular mechanisms underlying acquired epilepsy: The calcium hypothesis of the induction and maintainance of epilepsy[J]. Pharmacol Ther,2005, 105(3):229-66.
21. Makoto H, Nobuhisa I, Takaomi C. Saido. Understanding molecular mechanisms of proteolysis in Alzheimer's disease: Progress toward therapeutic interventions[J]. Biochimica et Biophysica Acta, 2005,1751(1):60- 7.
22. 2+ stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease [J]. Free Radical Biology Medicine,2005,39(8):979-89.