Chemical and biological applications of digital-microfluidic devices

IEEE Design and Test of Computers

Volumn 24, Issue 1, 2007, Pages 10-24

  Fair, Richard B ^a   Khlystov, Andrey ^a   Tailor, Tina D ^b   Ivanov, Vladislav ^a   Evans, Randall D ^c   Srinivasan, Vijay ^d   Pamula, Vamsee K ^d   Pollack, Michael G ^d   Griffin, Peter B ^e   Zhou, Jack ^f  

^a Duke University   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DUKE UNIVERSITY   (United States)

^d Advanced Liquid Logic Inc   (United States)

^e STANFORD UNIVERSITY   (United States)

^f Drexel University   (United States)

Author keywords

Analysis; Detection; Digital microfluidics; Electrowetting; Lab on a chip; Sample collection

Indexed keywords

BIOCHEMISTRY; BIOMEDICAL ENGINEERING; DIAGNOSIS; DNA; ELECTROCHEMISTRY; PHYSIOLOGY; WETTING;

DIAGNOSTIC APPLICATIONS; DIGITAL MICROFLUIDICS; ELECTROWETTING; LAB ON CHIP;

DIGITAL COMPUTERS;

EID: 34249814013     PISSN: 07407475     EISSN: None     Source Type: Journal    
DOI: 10.1109/MDT.2007.8     Document Type: Article

References (46)

1. M.G. Pollack, R.B. Fair, and A.D. Shenderov, "Electrowetting-Based Actuation of Liquid Droplets for Microfluidic Applications," Applied Physics Letters, vol. 77, no. 11, 11 Sept. 2000, pp. 1725-1726.
2. R.B. Fair et al., "Integrated Chemical/Biochemical Sample Collection, Pre-concentration, and Analysis on a Digital Microfluidic Lab-on-a-Chip Platform," Lab-on-a-Chip: Platforms, Devices, and Applications, L.A. Smith and D. Sobek, eds., (2004). Proc. SPIE, vol. 5591, 8 Dec. 2004, pp. 113-124.
3. V. K. Pamula et al., Apparatus for Manipulating Droplets by Electrowetting-Based Techniques, US patent 6,911, 132, Patent and Trademark Office, 2005.
4. P. Paik et al., "Electrowetting-Based Droplet Mixers for Microfluidic Systems, " Lab on a Chip, vol. 3, no. 1, 2003, pp. 28-33.
5. V. Srinivasan, V.K. Pamula, and R.B. Fair, "A Droplet-Based Microfluidic Lab-on-a-Chip for Glucose Detection," Analytica Chimica Acta, vol. 507, no. 1, 2004, pp. 145-150.
6. V. Srinivasan et al., "Clinical Diagnostics on Human Whole Blood, Plasma, Serum, Urine, Saliva, Sweat, and Tears on a Digital Microfluidic Platform," Proc. 7th Int'l Conf. Micro Total Analysis Systems (MicroTAS 03), Transducers Research Foundation, 2003, pp. 1287-1290.
7. P. Trinder, "Determination of Glucose in Blood Using Glucose Oxidase with an Alternative Oxygen Acceptor," Annals in Clinical Biochemistry, vol. 6, 1969, pp. 24-27.
8. V. Srinivasan, A Digital Microfluidic Lab-on-a-Chip for Clinical Diagnostic Applications, doctoral dissertation, Dept. of Electrical Eng., Duke Univ., 2005.
9. S.-K. Cho, H. Moon, and C.-J. Kim, "Creating, Transporting, Cutting, and Merging Liquid Droplets by Electrowetting-Based Actuation for Digital Microfluidic Circuits," IEEE/ASME J Microelectromechanical Systems, vol. 12, no. 1, Feb. 2003, pp. 70-80.
10. M.G. Pollack, A.D. Shenderov, and R.B. Fair, "Electrowetting-Based Actuation of Droplets for Integrated Microfluidics," Lab on a Chip vol. 2, no. 1, Feb. 2002, pp. 96-101.
11. J.-Y. Yoon and R.L. Garrell, "Preventing Biomolecular Adsorption on Electrowetting-Based Biofluidic Chips," Analytical Chemistry, vol. 75, no. 19, 1 Oct. 2003, pp. 5097-5102.
12. A.R. Wheeler et al., "Digital Microfluidics with In-Line Sample Purification for Proteomics Analyses with MLADI-MS," Analytical Chemistry, vol. 77, no. 2, 15 Jan. 2005, pp. 534-540.
13. H. Ren, V. Srinivasan, and R.B. Fair, "Design and Testing of an Interpolating Mixing Architecture for Electrowetting-Based Droplet On-Chip Chemical Dilution," Proc. 12th Int'l Conf. Transducers, Solid-State Sensors, Actuators and Microsystems, IEEE Press, vol. 1, 2003, pp. 619-622.
14. V.K. Pamula et al., "A Droplet-Based Lab-on-a-Chip for Colorimetric Detection of Nitroaromatic Explosives," Proc. 18th IEEE Int'l Conf. Micro Electro Mechanical Systems (MEMS 05), IEEE Press, 2005, pp. 722-725.
15. F. Terrier, "Rate and Equilibrium Studies in Jackson-Meisenheimer Complexes," Chemical Reviews, vol. 82, no. 2, Apr. 1982, pp. 77-152.
16. A. Peters et al., "Short-Term Effects of Particulate Air Pollution on Respiratory Morbidity in Asthmatic Children," European Respiratory J., vol. 10, no. 4, Apr. 1997, pp. 872-879.
17. C.A. Pope III, D.W. Dockery, and J. Schwartz, "Review of Epidemiological Evidence of Health Effects of Particulate Air Pollution, Inhalation Toxicology, vol. 7, 1995, pp. 1-18.
18. J.G. Watson, "Visibility: Science and Regulation," J. Air Waste Management Assoc., vol. 52, no. 6, 2002, pp. 628-713.
19. Y. Zhao and S.K. Cho, "Microparticle Sampling by Electrowetting-Actuated Droplet Sweeping," Lab on a Chip, vol. 6, no. 1, 2006, pp. 137-144.
20. B.C. Madsen and R.J. Murphy, "Flow Injection and Photometric Determination of Sulfate in Rainwater with Methylthymol Blue," Analytical Chemistry, vol. 53, no. 12, Oct. 1981, pp. 1924-1926.
21. J.H. Seinfeld and S.N. Pandis, Atmospheric Chemistry and Physics: From Air Pollution to Climate Change, John Wiley & Sons, 1998.
22. M.G. Pollack, Electrowetting-Based Microactuation of Droplets for Digital Microfluidics, doctoral dissertation, Dept. of Electrical Eng., Duke Univ., 2001.
23. M.J. Madou and R. Cubicciotti, "Scaling Issues in Chemical and Biological Sensors," Proc. IEEE, vol. 91, no. 6, June 2003, pp. 830-838.
24. C. Jurinke et al., "The Use of MassArray Technology for High Throughput Genotyping," Advances in Biochemical Engineering/Biotechnology, vol. 77, Springer 2002, pp. 57-74.
25. D.W. Deamer and M. Akeson, "Nanopores and Nucleic Acids: Prospects for Ultrarapid Sequencing," Trends in Biotechnology vol. 18, no. 4, Apr. 2000, pp. 147-151.
26. D.W. Deamer and D. Branton, "Characterization of Nucleic Acids by Nanopore Analysis," Accounts of Chemical Research, vol. 35, no. 10, Oct. 2002, pp. 817-825.
27. J. Li et al., "DNA Molecules and Configurations in a Solid-State Nanopore Microscope," Nature Materials, vol. 2, no. 9, Sept. 2003, pp. 611-615.
28. W. Bains and G.C. Smith, "A Novel Method for Nucleic Acid Sequence Determination," J. Theoretical Biology, vol. 135, no. 3, 1988, pp. 303-307.
29. E. M. Southern, Analyzing Polynucleotide Sequences, US patent WO/ 10977, Patent and Trademark Office, 1989.
30. S.P.A. Fodor et al., "Light-Directed, Spatially Addressable Parallel Chemical Synthesis," Science, vol. 251, no. 4995, 15 Feb. 1991, pp. 767-773.
31. S. Drmanac et al., "Accurate Sequencing by Hybridization for DNA Diagnostics and Individual Genomics," Nature Biotechnology, vol. 16, 1998, pp. 54-58.
32. S. Brenner et al., "In Vitro Cloning of Complex Mixtures of DNA on Microbeads: Physical Separation of Differentially Expressed cDNAs," Proc. Natl Academy of Science USA, vol. 97, no. 4, 15 Feb. 2000, pp. 1665-1670.
33. M.L. Metzker et al., "Termination of DNA Synthesis by Novel 3′-Modified-Deoxyribonucleoside 5′-Triphosphates," Nucleic Acids Research, vol. 22, no. 20, 11 Oct. 1994, pp. 4259-4267.
34. I. Braslavsky et al., "Sequence Information Can Be Obtained from Single DNA Molecules," Proc. Natl Academy of Science USA, vol. 100, no. 7, 1 Apr. 2003, pp. 3960-3964.
35. R. D. Mitra et al., "Digital Genotyping and Haplotyping with Polymerase Colonies," Proc. Natl Academy of Science USA, vol. 100, no. 10, 13 May 2003, pp. 5926-5931.
36. C.A. Emrich et al., "Microfabricated 384-Lane Capillary Array Electrophoresis Bioanalyzer for Ultrahigh-Throughput Genetic Analysis," Analytical Chemistry, vol. 74, no. 19, 1 Oct. 2002, pp. 5076-5083.
37. L. Koutny et al., "Eight Hundred-Base Sequencing in a Microfabricated Electrophoretic Device," Analytical Chemistry, vol. 72, no. 14, 15 July 2000, pp. 3388-3391.
38. B.M. Paegel, R.G. Blazej, and R.A. Mathies, "Microfluidic Devices for DNA Sequencing: Sample Preparation and Electrophoretic Analysis," Current Opinions in Biotechnology, vol. 14, no. 1, Feb. 2003, pp. 42-50.
39. M. Ronaghi, "Pyrosequencing Sheds Light on DNA Sequencing," Genome Research, vol. 11, no. 1, Jan. 2001, pp. 3-11.
40. M. Ronaghi et al., "Real-Time DNA Sequencing Using Detection of Pyrophosphate Release," Analytical Biochemistry, vol. 242, no. 1, 1 Nov. 1996, pp. 84-89.
41. J.L. Drury and D.J. Mooney, "Hydrogel for Tissue Engineering: Scaffold Design Variables and Applications," Biomaterials, vol. 24, no. 24, Nov. 2003, pp. 4337-4351.
42. T.M. Freyman, I.V. Yanna, and L.J. Gibson, "Cellular Materials as Porous Scaffolds for Tissue Engineering," Progress in Materials Science, vol. 46, no. 3, 2001, pp. 273-282.
43. N. Yuji et al., "Successful Clinical Application of Tissue-Engineered Graft for Extracardiac Fontan Operation," J. Thoracic and Cardiovascular Surgery, vol. 125, no. 2, Feb. 2003, pp. 419-420.
44. D.W. Hutmacher, "Polymeric Scaffolds in Tissue Engineering Bone and Cartilage," Biomaterials, vol. 21, 2000, pp. 2529-2543.
45. C. M. Smith et al., "Three-Dimensional BioAssembly Tool for Generating Viable Tissue-Engineered Constructs," Tissue Engineering, vol. 10, nos. 9-10, Sept. 2004, pp. 1566-1576.
46. F. Mugele and J.-C. Baret, "Electrowetting: From Basics to applications," J. Physics: Condensed Matter, vol. 17, no. 28, 20 July 2005, pp. R705-R774.