Nanopores and nucleic acids: Prospects for ultrarapid sequencing

Trends in Biotechnology

Volumn 18, Issue 4, 2000, Pages 147-151

  Deamer, David W ^a   Akeson, Mark ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HEMOLYSIN; NUCLEIC ACID; POLYMER; RNA;

NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SHORT SURVEY;

NASA DISCIPLINE EXOBIOLOGY; NON-NASA CENTER;

BACTERIAL TOXINS; FORECASTING; HEMOLYSIN PROTEINS; NUCLEIC ACIDS; PURINES; PYRIMIDINES; RNA; SEQUENCE ANALYSIS; SEQUENCE ANALYSIS, DNA;

EID: 0034177819     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-7799(00)01426-8     Document Type: Short Survey

References (7)

1. Sanger, F. et al. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
2. Maxam, A.M. and Gilbert, W. (1977) A new method for sequencing DNA. Proc. Natl. Acad. Sci. U. S. A. 74, 560-564
3. Song, L. et al. (1996) Structure of staphylococcal α-hemolysin, a heptameric transmembrane pore. Science 274, 1859-1865
4. Kasianowicz, J.J. et al. (1996) Characterization of individual polynucleotide molecules using a membrane channel. Proc. Natl. Acad. Sci. U. S. A. 93, 13770-13773
5. Akeson, M. et al. (1999) Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules. Biophys. J. 77, 3227-3233
6. Fasman, G.D. et al. (1964). The helical conformations of polycytidylic acid: studies on the forces involved. Biochemistry 3, 1015-1021
7. Saenger, W. et al. (1975). A structural model for the polyadenylic acid single helix. J. Mol. Biol. 93, 529-534