-
1
-
-
0032411879
-
Stress signals for apoptosis: Ceramide and c-Jun kinase
-
Basu, S. and Kolesnick, R., Stress signals for apoptosis: ceramide and c-Jun kinase. Oncogene, 17, 3277-3285 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 3277-3285
-
-
Basu, S.1
Kolesnick, R.2
-
2
-
-
17544366509
-
(1S,2R)-D-Erythro-2-(Nmyristolamino)-1-phenyl-1- propanol as an inhibitor of ceramidase
-
Bielawska, A., Greensberg, M., Perry, D., Jsysdev, S., Shayman, J. A., McKay, C., and Hannun, Y. A., (1S,2R)-D-Erythro-2-(Nmyristolamino)-1-phenyl-1- propanol as an inhibitor of ceramidase. J. Biol. Chem., 271, 12646-12654 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 12646-12654
-
-
Bielawska, A.1
Greensberg, M.2
Perry, D.3
Jsysdev, S.4
Shayman, J.A.5
McKay, C.6
Hannun, Y.A.7
-
3
-
-
0037043120
-
Synthesis and characterization of novel ceramide analogs for induction of apoptosis in human cancer cells
-
Bieberich, E., Hu, B., Silva, J., MacKinnon, S., Yu, R. K., Fillmore, H., Broaddus, W. C., and Ottenbrite, R. M., Synthesis and characterization of novel ceramide analogs for induction of apoptosis in human cancer cells. Cancer Letters, 181, 55-64 (2002).
-
(2002)
Cancer Letters
, vol.181
, pp. 55-64
-
-
Bieberich, E.1
Hu, B.2
Silva, J.3
MacKinnon, S.4
Yu, R.K.5
Fillmore, H.6
Broaddus, W.C.7
Ottenbrite, R.M.8
-
4
-
-
0034614414
-
N-acylated serinol is a novel ceramide mimic inducing apoptosis in neuroblastoma cells
-
Bieberich, E., Kawaguchi, T., and Yu, R. K., N-acylated serinol is a novel ceramide mimic inducing apoptosis in neuroblastoma cells. J. Biol. Chem., 275, 177-181 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 177-181
-
-
Bieberich, E.1
Kawaguchi, T.2
Yu, R.K.3
-
5
-
-
0029148660
-
-
Bose, R., Verheji, A., Haimovitz-Friedman., and Scottom, Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals. Cell, 82, 405-414 (1995).
-
Bose, R., Verheji, A., Haimovitz-Friedman., and Scottom, Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals. Cell, 82, 405-414 (1995).
-
-
-
-
6
-
-
33947291614
-
The synthesis and stereochemistry of the four isomeric pinane-2,3-diols
-
Carson, R. G. and Pierce, J. K., The synthesis and stereochemistry of the four isomeric pinane-2,3-diols. J. Org. Chem., 36, 2319-2324 (1971).
-
(1971)
J. Org. Chem
, vol.36
, pp. 2319-2324
-
-
Carson, R.G.1
Pierce, J.K.2
-
7
-
-
0037028921
-
The synthesis and biological characterization of a ceramide library
-
Chang, Y, T., Choi, J., Ding, S., Prieschl, E. E., Baumruker, T., Lee, J. M., Chung, S. K., and Schultz, P. G., The synthesis and biological characterization of a ceramide library. J. Am. Chem. Soc., 124, 1856-1857 (2002).
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 1856-1857
-
-
Chang, Y.T.1
Choi, J.2
Ding, S.3
Prieschl, E.E.4
Baumruker, T.5
Lee, J.M.6
Chung, S.K.7
Schultz, P.G.8
-
8
-
-
0023257811
-
Spectrometric quantitation of anchorage-dependent cell numbers extraction of naphthol blue-black-stained cellular protein
-
Everitt, E. and Wohlfart, C., Spectrometric quantitation of anchorage-dependent cell numbers extraction of naphthol blue-black-stained cellular protein. Anal. Biochem., 162, 122-129 (1987).
-
(1987)
Anal. Biochem
, vol.162
, pp. 122-129
-
-
Everitt, E.1
Wohlfart, C.2
-
9
-
-
17344380844
-
Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
-
Galve-Roperh, I., Sanchez, C., Cortes, M. L., Del Pulgar, T. G., Izquierdo, M., and Guzman, M., Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat. Med., 6, 313-319 (2000).
-
(2000)
Nat. Med
, vol.6
, pp. 313-319
-
-
Galve-Roperh, I.1
Sanchez, C.2
Cortes, M.L.3
Del Pulgar, T.G.4
Izquierdo, M.5
Guzman, M.6
-
10
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
-
Haimovitz-Friedman, A., Kan, C. C., Ehleiter, D., Persaud, R. S., McLoughlin, M., Fuks, Z., and Kolesnick, R. N., Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis., J. Exp. Med., 180, 525-535 (1994).
-
(1994)
J. Exp. Med
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedman, A.1
Kan, C.C.2
Ehleiter, D.3
Persaud, R.S.4
McLoughlin, M.5
Fuks, Z.6
Kolesnick, R.N.7
-
11
-
-
0030838165
-
Ceramide signaling in apoptosis
-
Haimovitz-Friedman, A., Kolesnick, R. N., and Fuks, Z., Ceramide signaling in apoptosis. Br. Med. Bull., 53, 539-553 (1997).
-
(1997)
Br. Med. Bull
, vol.53
, pp. 539-553
-
-
Haimovitz-Friedman, A.1
Kolesnick, R.N.2
Fuks, Z.3
-
12
-
-
30544445569
-
Functions of ceramide in coordination cellular response to stress
-
Hannun, Y., Functions of ceramide in coordination cellular response to stress. Science (Washington DC), 274, 18-1859 (1996).
-
(1996)
Science (Washington DC)
, vol.274
, pp. 18-1859
-
-
Hannun, Y.1
-
13
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr, I., Wilhelm, D., Bohler, T., Angel, P., and Debatin, K. M., Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J., 16, 6200-6208 (1997).
-
(1997)
EMBO J
, vol.16
, pp. 6200-6208
-
-
Herr, I.1
Wilhelm, D.2
Bohler, T.3
Angel, P.4
Debatin, K.M.5
-
14
-
-
0030006040
-
Daunorubicin-induced apoptosis: Triggering of ceramide generation through sphingomyelin hydrosis
-
Jaffrezou, J. P., Levade, T., Bettaieb, A., Andrieu, N., Bezombes, C., Maestre, N., Vermeersch, S., Rousse, A., and Laurent, G., Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrosis. EMBO J., 15, 2417-2424 (1996).
-
(1996)
EMBO J
, vol.15
, pp. 2417-2424
-
-
Jaffrezou, J.P.1
Levade, T.2
Bettaieb, A.3
Andrieu, N.4
Bezombes, C.5
Maestre, N.6
Vermeersch, S.7
Rousse, A.8
Laurent, G.9
-
15
-
-
0030051724
-
Modulation of druginduced apoptosis by interruption of the protein kinase C signal transduction pathway: A new therapeutic strategy. Ceramide and the induction of apoptosis
-
Jarvis, W., Grant, S., and Kolesnick, R. N., Modulation of druginduced apoptosis by interruption of the protein kinase C signal transduction pathway: a new therapeutic strategy. Ceramide and the induction of apoptosis. Clin. Cancer Res., 2, 1-6 (1996).
-
(1996)
Clin. Cancer Res
, vol.2
, pp. 1-6
-
-
Jarvis, W.1
Grant, S.2
Kolesnick, R.N.3
-
16
-
-
0031919157
-
Regulation of ceramide production and apoptosis
-
Kolesnick, R. N. and Kronke, M., Regulation of ceramide production and apoptosis. Annu. Rev. Physiol., 60, 643-665 (1998).
-
(1998)
Annu. Rev. Physiol
, vol.60
, pp. 643-665
-
-
Kolesnick, R.N.1
Kronke, M.2
-
17
-
-
0642312375
-
Synthesis and cytotoxicity of new 3-alkyl-1-(1-methyl-2-phenylethyl) ureas related to ceramide
-
Lim, S., Ryu, J. H., Im C., and Yim, C. B., Synthesis and cytotoxicity of new 3-alkyl-1-(1-methyl-2-phenylethyl) ureas related to ceramide. Arch Pharm Res., 26, 270-274 (2003).
-
(2003)
Arch Pharm Res
, vol.26
, pp. 270-274
-
-
Lim, S.1
Ryu, J.H.2
Im, C.3
Yim, C.B.4
-
18
-
-
0033194699
-
Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics
-
Lucci, A., Han, T. Y., Liu, Y. Y., Giuliano, A. E., and Cabot, M. C., Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics. Int. J. Oncol., 15, 541-546 (1999).
-
(1999)
Int. J. Oncol
, vol.15
, pp. 541-546
-
-
Lucci, A.1
Han, T.Y.2
Liu, Y.Y.3
Giuliano, A.E.4
Cabot, M.C.5
-
19
-
-
0029055676
-
Ceramide. A stress signal and mediator of growth suppression and apoptosis
-
Obeid, L. and Hannun, Y., Ceramide. A stress signal and mediator of growth suppression and apoptosis. J. Biol. Chem., 58, 191-198 (1995).
-
(1995)
J. Biol. Chem
, vol.58
, pp. 191-198
-
-
Obeid, L.1
Hannun, Y.2
-
20
-
-
0033566089
-
Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons
-
Overmeire, I. V., Swetlana, A. B., Dumont, P., Serge, V. C., Slegers, G., and Piet, H., Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons. J. Med. Chem., 42, 2697-2705 (1999).
-
(1999)
J. Med. Chem
, vol.42
, pp. 2697-2705
-
-
Overmeire, I.V.1
Swetlana, A.B.2
Dumont, P.3
Serge, V.C.4
Slegers, G.5
Piet, H.6
-
21
-
-
0034597611
-
Synthesis and biogical evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety
-
Overmeire, I. V., Swetlana, A. B., Krieshnan, V., Steven, D. J., and Piet, H., Synthesis and biogical evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety. J. Med. Chem., 43, 4189-4193 (2000).
-
(2000)
J. Med. Chem
, vol.43
, pp. 4189-4193
-
-
Overmeire, I.V.1
Swetlana, A.B.2
Krieshnan, V.3
Steven, D.J.4
Piet, H.5
-
22
-
-
0032497837
-
The role of ceramide in cell signaling
-
Perry, D. K. and Hannun, Y. A., The role of ceramide in cell signaling. Biochem. Biophys. Acta., 1436, 233-243 (1998).
-
(1998)
Biochem. Biophys. Acta
, vol.1436
, pp. 233-243
-
-
Perry, D.K.1
Hannun, Y.A.2
-
23
-
-
0034708594
-
Serine palmitoyltransferase regulates denovo ceramide generation during etoposide-induced apoptosis
-
Perry, D. K., Carton, J., Shah, A. K., Meredith, F., Uhlinger, D. J., and Hannun, Y. A., Serine palmitoyltransferase regulates denovo ceramide generation during etoposide-induced apoptosis. J. Biol. Chem., 275, 9078-9084 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9078-9084
-
-
Perry, D.K.1
Carton, J.2
Shah, A.K.3
Meredith, F.4
Uhlinger, D.J.5
Hannun, Y.A.6
-
24
-
-
0034829843
-
Killing cancer cells by poly-drug elevation of ceramide levels: A hypothesis whose time has come?
-
Radin, N. S., Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come? Eur. J. Biochem., 268, 193-204 (2001).
-
(2001)
Eur. J. Biochem
, vol.268
, pp. 193-204
-
-
Radin, N.S.1
-
25
-
-
34249804245
-
Studies on optically active amino acids. V. Synthesis of optically active alpha-aminoalcohols by the reduction of alpha-amino acid esters with sodium borohydride
-
Seki, H., Koga, K., Matsuo, H., Ohki, S., and Yamada, S., Studies on optically active amino acids. V. Synthesis of optically active alpha-aminoalcohols by the reduction of alpha-amino acid esters with sodium borohydride. Chem. Pharm. Bull., 4, 544 (1965).
-
(1965)
Chem. Pharm. Bull
, vol.4
, pp. 544
-
-
Seki, H.1
Koga, K.2
Matsuo, H.3
Ohki, S.4
Yamada, S.5
-
26
-
-
0035114217
-
Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer
-
Selzner, M., Bielawska, A., Morse, M. A., Rudiger, H. A., Sindram, D., Hannun, Y. A., and Clavien, P. A., Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. Cancer Res., 61, 1233-1240 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 1233-1240
-
-
Selzner, M.1
Bielawska, A.2
Morse, M.A.3
Rudiger, H.A.4
Sindram, D.5
Hannun, Y.A.6
Clavien, P.A.7
-
27
-
-
0035819885
-
Targeting ceramide metabolism a strategy for overcoming drug resistance
-
Senchenkov, A., Litvak, D. A., and Cabot, M. C., Targeting ceramide metabolism a strategy for overcoming drug resistance. J. Natl. Cancer Inst., 93, 347-357 (2001).
-
(2001)
J. Natl. Cancer Inst
, vol.93
, pp. 347-357
-
-
Senchenkov, A.1
Litvak, D.A.2
Cabot, M.C.3
-
28
-
-
0025341331
-
-
Skehan, P., Storeng, R., Scudiero, D. A., Monks, A., MacMahon, J., Via., Kenny, S., and Boyd, M..R., New colorimetric cytotoxicity assay for anticancer drug screening. J. Natl. Cancer Inst., 82, 1107-1112 (1990).
-
Skehan, P., Storeng, R., Scudiero, D. A., Monks, A., MacMahon, J., Via., Kenny, S., and Boyd, M..R., New colorimetric cytotoxicity assay for anticancer drug screening. J. Natl. Cancer Inst., 82, 1107-1112 (1990).
-
-
-
-
29
-
-
0024433138
-
Enantioselective synthesis of optically pure natural S(+) or unnatural R(-) DABA
-
Solladie-Cavallo, A. and Simon, M. C., Enantioselective synthesis of optically pure natural S(+) or unnatural R(-) DABA. Tetrahedron Lett., 30, 6011-6014 (1989).
-
(1989)
Tetrahedron Lett
, vol.30
, pp. 6011-6014
-
-
Solladie-Cavallo, A.1
Simon, M.C.2
-
30
-
-
0028364176
-
A four-step diastereoselective synthesis of D-erythro-sphingosine by an enantioselective aldol reaction using a titanium enolate derived from a chiral iminoglycinate
-
Solladie-Cavallo, A. and Kossler, J. L., A four-step diastereoselective synthesis of D-erythro-sphingosine by an enantioselective aldol reaction using a titanium enolate derived from a chiral iminoglycinate. J. Org. Chem., 59, 3240-3242 (1994).
-
(1994)
J. Org. Chem
, vol.59
, pp. 3240-3242
-
-
Solladie-Cavallo, A.1
Kossler, J.L.2
|