-
1
-
-
0018830636
-
Glucocorticoid-induced thymocyte apoptosis is associated with endonuclease activation
-
Wyllie AH. Glucocorticoid-induced thymocyte apoptosis is associated with endonuclease activation. Nature 1980; 284: 554-6
-
(1980)
Nature
, vol.284
, pp. 554-556
-
-
Wyllie, A.H.1
-
2
-
-
0027373764
-
Programmed cell death and the control of cell survival: Lessons from the nervous system
-
Raff MC, Barres BA, Burne JF et al. Programmed cell death and the control of cell survival: lessons from the nervous system. Science 1993; 262: 695-700
-
(1993)
Science
, vol.262
, pp. 695-700
-
-
Raff, M.C.1
Barres, B.A.2
Burne, J.F.3
-
3
-
-
0022497852
-
Genetic control of programmed cell death in the nematode C. elegans
-
Ellis HM, Horvitz HR. Genetic control of programmed cell death in the nematode C. elegans. Cell 1986; 44: 817-29
-
(1986)
Cell
, vol.44
, pp. 817-829
-
-
Ellis, H.M.1
Horvitz, H.R.2
-
4
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
-
Yuan J, Shaham S, Ledoux S et al. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 1993; 75: 641-52
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
-
5
-
-
0028297068
-
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling
-
Kolesnick R, Golde DW. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 1994; 77: 325-8
-
(1994)
Cell
, vol.77
, pp. 325-328
-
-
Kolesnick, R.1
Golde, D.W.2
-
6
-
-
0347537940
-
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
-
Verheij M, Bose R, Lin X H et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 1996; 380: 75-9
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Verheij, M.1
Bose, R.2
Lin, X.H.3
-
7
-
-
0029965593
-
Modulation of the apoptotic response: Potential for improving the outcome in clinical radiotherapy
-
Haimovitz-Friedman A, Kolesnick RN, Fuks Z. Modulation of the apoptotic response: potential for improving the outcome in clinical radiotherapy. Semin Radiat Oncol 1996; 6: 273-83
-
(1996)
Semin Radiat Oncol
, vol.6
, pp. 273-283
-
-
Haimovitz-Friedman, A.1
Kolesnick, R.N.2
Fuks, Z.3
-
8
-
-
0025283928
-
An update of the enzymology and regulation of sphingomyelin metabolism
-
Merrill Jr AH, Jones DD. An update of the enzymology and regulation of sphingomyelin metabolism. Biochim Biophys Acta 1990; 1044: 1-12
-
(1990)
Biochim Biophys Acta
, vol.1044
, pp. 1-12
-
-
Merrill Jr., A.H.1
Jones, D.D.2
-
9
-
-
0025944874
-
Sphingomyelin and derivatives as cellular signals
-
Kolesnick RN. Sphingomyelin and derivatives as cellular signals. Prog Lipid Res 1991; 30: 1-38
-
(1991)
Prog Lipid Res
, vol.30
, pp. 1-38
-
-
Kolesnick, R.N.1
-
10
-
-
0029012443
-
Acid sphingomyelinase deficient mice: A model of types A and B Niemann-Pick disease
-
Horinouchi K, Erlich S, Perl D et al. Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease. Nature Genet 1995; 10: 288-93
-
(1995)
Nature Genet
, vol.10
, pp. 288-293
-
-
Horinouchi, K.1
Erlich, S.2
Perl, D.3
-
13
-
-
0028108015
-
Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
-
Wiegmann K, Schutze S, Machleidt T et al. Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 1994; 78: 1005-15
-
(1994)
Cell
, vol.78
, pp. 1005-1015
-
-
Wiegmann, K.1
Schutze, S.2
Machleidt, T.3
-
14
-
-
0028078720
-
Induction of apoptotic DNA degradation and cell death by activation of the sphingomyelin pathway
-
Jarvis DW, Kolesnick RN, Fornari FA et al. Induction of apoptotic DNA degradation and cell death by activation of the sphingomyelin pathway. Proc Natl Acad Sci USA 1994; 91: 73-7
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 73-77
-
-
Jarvis, D.W.1
Kolesnick, R.N.2
Fornari, F.A.3
-
15
-
-
0027511687
-
Programmed cell death induced by ceramide
-
Obeid LM, Linardi CM, Karolak LA et al. Programmed cell death induced by ceramide. Science 1993; 259: 1769-71
-
(1993)
Science
, vol.259
, pp. 1769-1771
-
-
Obeid, L.M.1
Linardi, C.M.2
Karolak, L.A.3
-
16
-
-
0028964917
-
Fas-induced apoptosis is mediated by a ceramide-initiated RAS signaling pathway
-
Gulbins E, Bissonnette R, Mahbouti A et al. Fas-induced apoptosis is mediated by a ceramide-initiated RAS signaling pathway. Immunity 1995; 2: 341-51
-
(1995)
Immunity
, vol.2
, pp. 341-351
-
-
Gulbins, E.1
Bissonnette, R.2
Mahbouti, A.3
-
17
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and induce apoptosis
-
Haimovitz-Friedman A, Kan C-C, Ehleiter D. et al. Ionizing radiation acts on cellular membranes to generate ceramide and induce apoptosis. J Exp Med 1994; 180: 525-35
-
(1994)
J Exp Med
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedman, A.1
Kan, C.-C.2
Ehleiter, D.3
-
18
-
-
16044364385
-
Acid sphingomyelinase deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
Santana P, Peña LA, Haimovitz-Friedman A et al. Acid sphingomyelinase deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell 1996; 86: 189-99
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Peña, L.A.2
Haimovitz-Friedman, A.3
-
19
-
-
0026560014
-
Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system
-
Dressier KA, Mathias S, Kolesnick RN. Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system. Science 1992; 255: 1715-8
-
(1992)
Science
, vol.255
, pp. 1715-1718
-
-
Dressier, K.A.1
Mathias, S.2
Kolesnick, R.N.3
-
20
-
-
0028784298
-
Compartmentalized production of ceramide at the cell surface
-
Liu P, Anderson RG. Compartmentalized production of ceramide at the cell surface. J Biol Chem 1995; 270: 27179-85
-
(1995)
J Biol Chem
, vol.270
, pp. 27179-27185
-
-
Liu, P.1
Anderson, R.G.2
-
21
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis JM, Banerjee P, Nikolakaki E et al. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 1994; 369: 156-60
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
-
22
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J et al. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326-31
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
-
23
-
-
0029948396
-
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
-
Cuvillier O, Pirianov G, Kleuser B et al. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 1996; 381: 800-3
-
(1996)
Nature
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Pirianov, G.2
Kleuser, B.3
-
24
-
-
0030298294
-
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
-
Liu ZG, Hsu H, Goeddel DV et al. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 1996; 87: 565-76
-
(1996)
Cell
, vol.87
, pp. 565-576
-
-
Liu, Z.G.1
Hsu, H.2
Goeddel, D.V.3
-
25
-
-
0027449187
-
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
-
Miura M, Zhu H, Rotello R et al. Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 1993; 75: 653-60
-
(1993)
Cell
, vol.75
, pp. 653-660
-
-
Miura, M.1
Zhu, H.2
Rotello, R.3
-
26
-
-
0029995766
-
License to kill
-
Fraser A, Evan GA. License to kill. Cell 1996; 85: 781-4
-
(1996)
Cell
, vol.85
, pp. 781-784
-
-
Fraser, A.1
Evan, G.A.2
-
27
-
-
0029787268
-
Molecular ordering of apoptotic mammalian CED-3/ ICE-like proteases
-
Orth K, O'Rourke K, Salvesen GS et al. Molecular ordering of apoptotic mammalian CED-3/ ICE-like proteases. J Biol Chem 1996; 271: 20977-80
-
(1996)
J Biol Chem
, vol.271
, pp. 20977-20980
-
-
Orth, K.1
O'Rourke, K.2
Salvesen, G.S.3
-
28
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik YA, Kaufmann SH, Desnoyeres S et al. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 1994; 371: 346-7
-
(1994)
Nature
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyeres, S.3
-
29
-
-
0027275490
-
A novel domain within the 55 kDa TNF receptor signals cell death
-
Tartaglia LA, Ayres TM, Wong GHW et al. A novel domain within the 55 kDa TNF receptor signals cell death. Cell 1993; 74: 845-53
-
(1993)
Cell
, vol.74
, pp. 845-853
-
-
Tartaglia, L.A.1
Ayres, T.M.2
Wong, G.H.W.3
-
30
-
-
0029965280
-
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
-
Chinnaiyan AM, Tepper CG, Seldin MF et al. FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem 1996; 271: 4961-5
-
(1996)
J Biol Chem
, vol.271
, pp. 4961-4965
-
-
Chinnaiyan, A.M.1
Tepper, C.G.2
Seldin, M.F.3
-
31
-
-
0028985261
-
Self-association of the 'death domains' of the p55 tumor necrosis factor (TNF) receptor and the Fas/APO1 prompts signaling for TNF and Fas/ APO1 effects
-
Boldin MP, Mett IL, Varfolomeev EE et al. Self-association of the 'death domains' of the p55 tumor necrosis factor (TNF) receptor and the Fas/APO1 prompts signaling for TNF and Fas/ APO1 effects. J Biol Chem 1995; 270: 387-91
-
(1995)
J Biol Chem
, vol.270
, pp. 387-391
-
-
Boldin, M.P.1
Mett, I.L.2
Varfolomeev, E.E.3
-
32
-
-
0028790239
-
Multiple pathways originate at the Fas/APO-1 (CD95) receptor: Sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal
-
Cifone MG, Roncaioli P, De Maria R et al. Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal. EMBO J 1995; 14: 5859-68
-
(1995)
EMBO J
, vol.14
, pp. 5859-5868
-
-
Cifone, M.G.1
Roncaioli, P.2
De Maria, R.3
-
33
-
-
0029912189
-
Molecular ordering of the cell death pathway
-
Chinnaiyan AM, Orth K, O'Rourke K et al. Molecular ordering of the cell death pathway. J Biol Chem 1996; 271: 4573-6
-
(1996)
J Biol Chem
, vol.271
, pp. 4573-4576
-
-
Chinnaiyan, A.M.1
Orth, K.2
O'Rourke, K.3
-
34
-
-
0030060075
-
Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER
-
Pronk GJ, Ramer K, Amiri P et al. Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science 1995; 271: 808-10
-
(1995)
Science
, vol.271
, pp. 808-810
-
-
Pronk, G.J.1
Ramer, K.2
Amiri, P.3
-
35
-
-
9344222195
-
Bcl-2 interrupts the ceramide-mediated pathway of cell death
-
Zhang J, Alter N, Reed JC et al. Bcl-2 interrupts the ceramide-mediated pathway of cell death. Proc Natl Acad Sci USA 1996; 93: 5325-8
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5325-5328
-
-
Zhang, J.1
Alter, N.2
Reed, J.C.3
-
36
-
-
0029949938
-
PrICE: A downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2
-
Smyth MJ, Perry DK, Zhang J et al. prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2. Biochem J 1996; 316: 25-8
-
(1996)
Biochem J
, vol.316
, pp. 25-28
-
-
Smyth, M.J.1
Perry, D.K.2
Zhang, J.3
-
37
-
-
0029881489
-
Free radical mediated X-ray damage of model membranes
-
Chen A, Caffrey MO. Free radical mediated X-ray damage of model membranes. Biophys J 1996; 70: 2212-22
-
(1996)
Biophys J
, vol.70
, pp. 2212-2222
-
-
Chen, A.1
Caffrey, M.O.2
-
38
-
-
0027049804
-
The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases
-
Devary Y, Gottlieb RA, Smeal T et al. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 1996; 71: 1081-91
-
(1996)
Cell
, vol.71
, pp. 1081-1091
-
-
Devary, Y.1
Gottlieb, R.A.2
Smeal, T.3
-
39
-
-
13344259987
-
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells
-
Emoto Y, Manome Y, Meinhardt G et al. Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J 1995; 14: 6148-56
-
(1995)
EMBO J
, vol.14
, pp. 6148-6156
-
-
Emoto, Y.1
Manome, Y.2
Meinhardt, G.3
-
40
-
-
0029061402
-
Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family
-
Korsmeyer SJ, Yin XM, Oltvai ZN et al. Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family. Biochim Biophys Acta 1995; 1271: 63-6
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 63-66
-
-
Korsmeyer, S.J.1
Yin, X.M.2
Oltvai, Z.N.3
-
41
-
-
0030584079
-
Apoptosis meets signal transduction: Elimination of BAD influence
-
Kajewski TF, Thompson CB. Apoptosis meets signal transduction: elimination of BAD influence. Cell 1966; 87: 589-92
-
(1966)
Cell
, vol.87
, pp. 589-592
-
-
Kajewski, T.F.1
Thompson, C.B.2
-
42
-
-
0029899181
-
Molecular thanatopsis: A discourse on the BCL2 family and cell death
-
Yang E, Korsmeyer SJ. Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 1996; 88: 386-401
-
(1996)
Blood
, vol.88
, pp. 386-401
-
-
Yang, E.1
Korsmeyer, S.J.2
-
43
-
-
0028928295
-
Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide
-
Chen M, Quintans J, Fuks Z et al. Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide. Cancer Res 1995; 55: 991-4
-
(1995)
Cancer Res
, vol.55
, pp. 991-994
-
-
Chen, M.1
Quintans, J.2
Fuks, Z.3
-
44
-
-
1842413418
-
An essential role for NF-κB in preventing TNF-α-induced cell death
-
Beg AA, Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 1966; 274: 784
-
(1966)
Science
, vol.274
, pp. 784
-
-
Beg, A.A.1
Baltimore, D.2
-
45
-
-
0038914800
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
Wang CY, Mayo MW, Baldwin AS. TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 1966; 274: 782-7
-
(1966)
Science
, vol.274
, pp. 782-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin, A.S.3
-
46
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κB
-
Van Antwerp DJ, Martin SA, Kafri T et al. Suppression of TNF-α-induced apoptosis by NF-κB. Science 1966; 274: 787-9
-
(1966)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.A.2
Kafri, T.3
-
48
-
-
0028302712
-
Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis
-
Haimovitz-Friedman A, Balaban NA, McLoughlin M et al. Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis. Cancer Res 1994; 54: 2591-7
-
(1994)
Cancer Res
, vol.54
, pp. 2591-2597
-
-
Haimovitz-Friedman, A.1
Balaban, N.A.2
McLoughlin, M.3
-
49
-
-
0028046589
-
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells
-
Jarvis WD, Fornari Jr FA, Browning JL et al. Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells. J Biol Chem 1994; 269: 31685-92
-
(1994)
J Biol Chem
, vol.269
, pp. 31685-31692
-
-
Jarvis, W.D.1
Fornari Jr., F.A.2
Browning, J.L.3
-
51
-
-
0345498292
-
Bcl-2 targets the protein kinase Raf-1 to mitochondria
-
Wang HG, Rapp UR, Reed JC. Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 1996; 87: 629-638
-
(1996)
Cell
, vol.87
, pp. 629-638
-
-
Wang, H.G.1
Rapp, U.R.2
Reed, J.C.3
-
53
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
Zamzami N, Susin SA, Marchetti P et al. Mitochondrial control of nuclear apoptosis. J Exp Med 1996; 183: 1533-44
-
(1996)
J Exp Med
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
Susin, S.A.2
Marchetti, P.3
-
54
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J et al. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996; 86: 147-57
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
-
55
-
-
0029982148
-
The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition
-
Passtorino JG, Simbula G, Yamamoto K et al. The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition. J Biol Chem 1996; 271: 29792-8
-
(1996)
J Biol Chem
, vol.271
, pp. 29792-29798
-
-
Passtorino, J.G.1
Simbula, G.2
Yamamoto, K.3
-
56
-
-
33750132435
-
Intravenous basic fibroblast growth factor protects the lung but not mediastinal organs against radiation-induced apoptosis in vivo
-
Fuks Z, Alfieri A, Haimovitz-Friedman A et al. Intravenous basic fibroblast growth factor protects the lung but not mediastinal organs against radiation-induced apoptosis in vivo. Can J Sci Am 1995; 1: 62-72
-
(1995)
Can J Sci Am
, vol.1
, pp. 62-72
-
-
Fuks, Z.1
Alfieri, A.2
Haimovitz-Friedman, A.3
-
57
-
-
0029869593
-
Selective activation of NF-κB by nerve growth factor through the neurotrophin regulator p75
-
Carter BD, Kaltschmidt C, Kaltschmidt B et al. Selective activation of NF-κB by nerve growth factor through the neurotrophin regulator p75. Science 1996; 272: 542-5
-
(1996)
Science
, vol.272
, pp. 542-545
-
-
Carter, B.D.1
Kaltschmidt, C.2
Kaltschmidt, B.3
|