Chronic exposure to morphine and naltrexone induces changes in catecholaminergic neurotransmission in rat brain without altering μ-opioid receptor sensitivity

Life Sciences

Volumn 52, Issue 21, 1993, Pages 1685-1693

  De Vries, Taco J ^a   Tjon Tien Ril, Guno H K ^a   Van der Laan, Jan Willem ^b   Mulder, Arie H ^a   Schoffelmeer, Anton N M ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ADENYLATE CYCLASE; CYCLIC AMP; DOPAMINE 1 RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MORPHINE; MU OPIATE RECEPTOR; NALTREXONE; NORADRENALIN; RADIOLIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; BRAIN SLICE; CATECHOLAMINERGIC SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; LIGAND BINDING; MALE; MORPHINE ADDICTION; MORPHINE TOLERANCE; NEUROTRANSMISSION; NONHUMAN; NORADRENALIN RELEASE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; SUPERSENSITIVITY;

ADENYLATE CYCLASE; ANIMAL; BINDING SITES; BRAIN; CATECHOLAMINES; CYCLIC AMP; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALINS; MALE; MORPHINE; NALTREXONE; NOREPINEPHRINE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D1; RECEPTORS, OPIOID, MU; SUPPORT, NON-U.S. GOV'T;

ANIMALIA;

EID: 0027466794     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(93)90476-J     Document Type: Article

References (47)

1. Chronic naltrexone supersensitizes the reinforcing and locomotor-activating effects of morphine