Impaired motor functions in mice lacking the RNA-binding protein Hzf

Neuroscience Research

Volumn 58, Issue 2, 2007, Pages 183-189

  Iijima, Takatoshi ^a   Ogura, Hiroo ^b   Takatsuki, Kanako ^c   Kawahara, Shigenori ^c   Wakabayashi, Kenichiro ^a   Nakayama, Daisuke ^a   Fujioka, Masato ^a   Kimura, Yuki ^d   Bernstein, Alan ^d   Okano, Hirotaka James ^a   Kirino, Yutaka ^c   Okano, Hideyuki ^a  

^a KEIO UNIVERSITY   (Japan)

^b EISAI CO LTD   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Hzf; Motor coordination; Motor learning; mRNA localization; Neuronal RNA binding protein; Purkinje cell

Indexed keywords

MESSENGER RNA; PROTEIN HZF; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBELLUM CORTEX; CONTROLLED STUDY; DISEASE SEVERITY; LEARNING; MEMORY; MOTOR ACTIVITY; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; MUSCLE STRENGTH; NONHUMAN; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; ANIMALS; CEREBELLAR DISEASES; CONDITIONING, CLASSICAL; LEARNING DISORDERS; MALE; MAZE LEARNING; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; MOTOR SKILLS DISORDERS; PATTERN RECOGNITION, VISUAL; PROTEINS; REACTION TIME;

EID: 34249733625     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.02.013     Document Type: Article

References (40)

1. Aiba A., Kano M., Chen C., Stanton M.E., Fox G.D., Herrup K., Zwingman T.A., and Tonegawa S. Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell 79 (1994) 377-388
2. Brown V., Jin P., Ceman S., Darnell J.C., O'Donnell W.T., Tenenbaum S.A., Jin X., Feng Y., Wilkinson K.D., Keene J.D., Darnell R.B., and Warren S.T. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell 107 (2001) 477-487
3. Clark R.E., Zola S.M., and Squire L.R. Impaired recognition memory in rats after damage to the hippocampus. J. Neurosci. 20 (2000) 8853-8860 similar results
4. Furuichi T., Yosikawa S., Miyawaki A., Wada K., Maeda N., and Mikoshiba K. Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400. Nature 342 (1989) 32-38
5. Hidaka M., Caruana G., Stanford W.L., Sam M., Correll P.H., and Bernstein A. Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells. Mech. Dev. 90 (2000) 3-15
6. Houchi H., Babovic D., Pierrefiche O., Ledent C., Daoust M., and Naassila M. CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors. Neuropsychopharmacology 30 (2005) 339-349
7. Huber K.M., Kayser M.S., and Bear M.F. Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression. Science 288 (2000) 1254-1257
8. Huber K.M., Gallagher M.S., Warren S.T., and Bear M.F. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc. Natl. Acad. Sci. USA 99 (2002) 7746-7750
9. Iijima T., Imai T., Kimura Y., Bernstein A., Okano H.J., Yuzaki M., and Okano H. Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4, 5-trisphosphate receptor mRNA. Proc. Natl. Acad. Sci. USA 102 (2005) 17190-17195
10. Inoue T., Kato K., Kohda K., and Mikoshiba K. Type1 inositol 1,4, 5-triphosphatase receptor is required for induction of long-term depression in cerebellar Purkinje neurons. J. Neurosci. 18 (1998) 5366-5373
11. Ito M. Long-term depression. Annu. Rev. Neurosci. 12 (1989) 85-102
12. Kanai Y., Dohmae N., and Hirokawa N. Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron 43 (2004) 513-525
13. Kang H., and Schuman E.M. A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science 273 (1996) 1402-1406
14. Kelleher R.J., Govindarajan III A., Jung H.Y., Kang H., and Tonegawa S. Translational control by MAPK signaling in long-term synaptic plasticity and memory. Cell 116 (2004) 467-479
15. Kiebler M.A., Hemraj I., Verkade P., Kohrmann M., Fortes P., Marion R.M., Ortin J., and Dotti C.G. The mammalian Staufen protein localized to the somatodendritic domain of cultured hippocampal neurons: implications for its involvement in mRNA transport. J. Neurosci. 19 (1999) 288-297
16. Kimura Y., Hart A., Hirashima M., Wang C., Holmyard D., Pittman J., Pang X.L., Jackson C.W., and Bernstein A. Zinc finger protein, Hzf, is required for megakaryocyte development and hemostasis. J. Exp. Med. 195 (2002) 941-952
17. Kishimoto Y., Kawahara S., Suzuki M., Mori H., Mishina M., and Kirino Y. Classical eyeblink conditioning in glutamate receptor subunit δ2 mutant mice is impaired in the delay paradigm but not in the trace paradigm. Eur. J. Neurosci. 13 (2001) 1249-1253
18. Kishimoto Y., Hirono M., Sugiyama T., Kawahara S., Nakao K., Kishio M., Katsuki M., Yoshioka T., and Kirino Y. Impaired delay but normal trace eyeblink conditioning in PLCβ4 mutant mice. Neuroreport 12 (2001) 2919-2922
19. Koekkoek S.K., Hulscher H.C., Dortland B.R., Hensbroek R.A., Elgersma Y., Ruigrok T.J., and De Zeeuw C.I. Cerebellar LTD and learning-dependent timing of conditioned eyelid responses. Science 301 (2003) 1736-1739
20. Koekkoek S.K., Yamaguchi K., Milojkovic B.A., Dortland B.R., Ruigrok T.J., Maex R., De Graaf W., Smit A.E., VanderWerf F., Bakker C.E., Willemsen R., Ikeda T., Kakizawa S., Onodera K., Nelson D.L., Mientjes E., Joosten M., De Schutter E., Oostra B.A., Ito M., and De Zeeuw C.I. Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome. Neuron 47 (2005) 339-352
21. Kohrmann M., Luo M., Kaether C., DesGroseillers L., Dotti C.G., and Kiebler M.A. Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons. Mol. Biol. Cell. 10 (1999) 2945-2953
22. Kooy R.F. Of mice and the fragile X syndrome. Trends Genet. 19 (2003) 148-154 Review
23. Linden D.J. A protein synthesis-dependent late phase of cerebellar long-term depression. Neuron 17 (1996) 483-490
24. Matsumoto M., Nakagawa T., Inoue T., Nagata E., Tanaka K., Takano H., Minowa O., Kuno J., Sakakibara S., Yamada M., Yoneshima H., Miyawaki A., Fukuuchi Y., Furuichi T., Okano H., Mikoshiba K., and Noda T. Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature 379 (1996) 168-171
25. Li J., Pelletier M.R., Perez Velazquez J.L., and Carlen P.L. Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency. Mol. Cell. Neurosci. 19 (2002) 138-151
26. Mikics E., Dombi T., Barsvari B., Varga B., Ledent C., Freund T.F., and Haller J. The effects of cannabinoids on contextual conditioned fear in CB1 knockout and CD1 mice. Behav. Pharmacol. 17 (2006) 223-230
27. Miller S., Yasuda M., Coats J.K., Jones Y., Martone M.E., and Mayford M. Disruption of dendritic translation of CaMKII alpha impairs stabilization of synaptic plasticity and memory consolidation. Neuron 36 (2002) 507-519
28. Miyashiro K.Y., Beckel-Mitchener A., Purk T.P., Becker K.G., Barret T., Liu L., Carbonetto S., Weiler I.J., Greenough W.T., and Eberwine J. RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron 37 (2003) 417-431
29. Moyer J.R.J., Deyo R.A., and Disterhoft J.F. Hippocampectomy disrupts trace eye-blink conditioning in rabbits. Behav. Neurosci. 104 (1990) 243-252
30. Ogura H., Aruga J., and Mikoshiba K. Behavioral abnormalities of Zic1 and Zic2 mutant mice: implications as models for human neurological disorders. Behav. Genet. 31 (2001) 317-324
31. Ogura H., Matsumoto M., and Mikoshiba K. Motor discoordination in mutant mice heterozygous for the type 1 inositol 1,4,5-trisphosphate receptor. Behav. Brain Res. 122 (2001) 215-219
32. Ross A.F., Oleynikov Y., Kislauskis E.H., Taneja K.L., and Singer R.H. Characterization of a beta-actin mRNA zipcode-binding protein. Mol. Cell. Biol. 17 (1997) 2158-2165
33. Shibuki K., Gomi H., Chen L., Bao S., Kim J.J., Wakatsuki H., Fujisaki T., Fujimoto K., Katoh A., Ikeda T., Chen C., Thompson R.F., and Itohara S. Deficient cerebellar long-term depression, impaired eyeblink conditioning, and normal motor coordination in GFAP mutant mice. Neuron 16 (1996) 587-599
34. Steward O., and Schuman E.M. Protein synthesis at synaptic sites on dendrites. Annu. Rev. Neurosci. 24 (2001) 299-325 review
35. Takehara K., Kawahara S., and Kirino Y. Time-dependent reorganization of the brain components underlying memory retention in trace eyeblink conditioning. J. Neurosci. 23 (2003) 9897-9905
36. Thompson R.F., Bao S., Chen L., Cipriano B.D., Grethe J.S., Kim J.J., Thompson J.K., Tracy J.A., Weninger M.S., and Krupa D.J. Associative learning. Int. Rev. Neurobiol. 41 (1997) 151-189 review
37. Tiruchinapalli D.M., Oleynikov Y., Kelic S., Shenoy S.M., Hartley A., Stanton P.K., Singer R.H., and Bassell G.J. Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons. J. Neurosci. 23 (2003) 3251-3261
38. Weiss C., Bouwmeester H., Power J.M., and Disterhoft J.F. Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat. Behav. Brain Res. 99 (1991) 123-132
39. Woodruff-Pak D.S., Lavond D.G., and Thompson R.F. Trace conditioning: abolished by cerebellar nuclear lesions but not lateral cerebellar cortex aspirations. Brain Res. 348 (1985) 249-260
40. Zhang H.L., Eom T., Oleynikov Y., Shenoy S.M., Liebelt D.A., Dictenberg J.B., Singer R.H., and Bassell G.J. Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility. Neuron 31 (2001) 261-275