Potential mucoadhesive dosage form of lidocaine hydrochloride: II. In vitro and in vivo evaluation

Drug Development and Industrial Pharmacy

Volumn 33, Issue 4, 2007, Pages 437-448

  Abu Huwaij, Rana ^a   Assaf, Shereen ^b   Salem, Mutaz ^b   Sallam, Alsayed ^c  

^a AL AHLIYYA AMMAN UNIVERSITY   (Jordan)

^b JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

^c Specilized Pharm Research Company (STD)   (Jordan)

Author keywords

Buccal patch; Carbopol; In vitro release; Lidocaine hydrochloride; Permeability

Indexed keywords

BUPIVACAINE; CARBOMER; ETHYLENE VINYL ACETATE COPOLYMER; GLYCEROL; LIDOCAINE; OLEIC ACID; PENETRATION ENHANCING AGENT; POLOXAMER; POLYMER; POLYSORBATE 20; PROPANEDIOL DERIVATIVE; PROPYLENE GLYCOL MONOLAURATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHEEK MUCOSA; CONTROLLED STUDY; DIFFUSION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG MECHANISM; DRUG PENETRATION; DRUG RELEASE; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; MICELLE; NONHUMAN; RABBIT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ACRYLATES; ADHESIVENESS; ADMINISTRATION, BUCCAL; ANESTHETICS, LOCAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; EXCIPIENTS; GLYCEROL; LAURATES; LIDOCAINE; MOUTH MUCOSA; OLEIC ACID; PERMEABILITY; POLYSORBATES; POLYVINYLS; PROPYLENE GLYCOLS; RABBITS; SWINE;

EID: 34249331332     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040601150211     Document Type: Article

References (41)

1. Arakawa, Y., Kawakami, S., Yamashita, F., & Hashida, M.(2005). Effect of low-molecular-weight beta-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms. Biological & Pharmaceutical Bulletin, 28(9), 1679-83.
2. Artusi, M., Santi, P., Colombo, P., & Junginger, H. (2003). Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. International Journal of Pharmaceutics, 250, 203-213.
3. Aungst, B., & Rogers, N. (1989). Comparison of the effects of various transmucosal absorption promoters on buccal insulin delivery. International Journal of Pharmaceutics, 53, 227-235.
4. Bredenberg, S., Duberg, M., Lennernäs, B., Lennernäs, H., Pettersson, A., Westerberg, M., & Nyström, C. (2003). In vitro and in vivo evaluation of a new sublingual tablet system for rapid oromucosal absorption using fentanyl citrate as the active substance. European Journal of Pharmaceutical Sciences, 20, 327-334.
5. Burgalassi, S., Panichi, L., Saettone, M., Jacobsen, J., & Rassing, M. (1996). Development and in vitro/in vivo testing of mucoadhesive buccal patches releasing benzydamine and lidocaine. International Journal of Pharmaceutics, 133, 1-7.
6. Cui, Z., & Mumper, R. (2002). Bilayer films for mucosal (genetic) immunization via the buccal route in rabbits. Pharmaceutical Research, 19(7), 947-953.
7. Deneer, V., Drese, G., Roemele, P., Verhoef. J., Huen, L., Kingma, J., Brouwers, J., & Junginger, H. Buccal transport of flecaininde and sotalol: effect of a bile salt and ionization state. International Journal of Pharmaceutics, 241, 127-134.
8. Dollo, G., Estebe, J., Corre, P., Chevanne, F., Ecoffey, C., & Verge, R. (2001). Endotracheal tube cuffs filled with lidocaine as a drug delivery system: in vitro and in vivo investigations. European Journal of Pharmaceutical Sciences, 13, 319-323.
9. Gandhi, R., & Robinson, J. (1992). Mechanism of penetration enhancement for transbuccal delivery of salicylic acid. International Journal of Pharmaceutics, 85, 129-140.
10. Ganem-Quintanar, A., Quintanar-Guerrero, D., Falson-Rieg, F., & Buri, P. (1998). Ex vivo oral mucosal permeation of lidocaine hydrochloride with sucrose fatty acid esters as absorption enhancers. International Journal of Pharmaceutics, 173, 203-210.
11. Guo, J., & Cooklock, K. (1996). The effect of backing materials and multilayered systems on the characteristics of bioadhesive buccal patches. Journal of Pharmacy and Pharmacology, 48, 255-257.
12. Hao, J., & Heng, P. (2003). Buccal delivery systems. Drug Development and Industrial Pharmacy, 29(8), 821-832.
13. Heusler, H. (1985). Quantitative analysis of common anaesthetic agents. Journal of Chromatography, 340, 273-319.
14. Jay, S., Fountain, W., Cui, Z., & Mumper, R. (2002). Transmucosal delivery of testosterone in rabbits using novel bi-layer mucoadhesive wax film composite disks. Journal of Pharmaceutical Sciences, 91(9), 2016-2025.
15. Kabanov, A., Batrakova, E., & Alakhov, V. (2002). Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery. Journal of Controlled Release, 82, 189-212.
16. Kabanov, A., Batrakova, E., & Miller, D. (2003). Pluronic block copolymers as modulators of drug efflux transporter activity in the blood-brain barrier. Advanced Drug delivery Reviews, 55, 151-164.
17. Kang, L., Jun, H., & McCall, J. (1999). HPLC assay of Lidocaine in plasma with solid phase extraction and UV detection. Journal of Pharmaceutical and Biomedical Analysis, 19, 737-745.
18. Katzung, B. (1998). Basic and Clinical Pharmacology, (7th Ed.); Chapter 14.
19. Khanna, R., Agarwal, S., & Ahuja, A. (1997). Muco-adhesive buccal tablets of clotrimazole for oral candidiasis. Drug Development and Industrial Pharmacy, 23(8), 831-837.
20. Klein, J., Fernandes, D., Gazarian, M., Kent, G., & Koren, G. (1994). Simultaneous determination of lidocaine, prilocaine and the prilocaine metabolite o-toluidine in plasma by high performance liquid chromatography. Journal of Chromatography B, 655, 83-88.
21. Lee, J., Park, J., & Robinson, J. (2000). Bioadhesive-based dosage forms; the next generation. Journal of Pharmaceutical Sciences, 89(7), 850-866.
22. Lopez, C., Portero, A., Jato, J., & Alonso, M. (1998). Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery. Journal of Controlled Release, 55, 143-152.
23. Neal, C., & Poklis, A. (1996). Sensitive HPLC for simultaneous quantification of lidocaine and its metabolites monoethylglycinexylidide and glycinexylidide in serum. Clinical Chemistry, 42(2), 330-331.
24. Okamoto, H., Nakamori, T., Arakawa, Y., Iida, K., & Danjo, K. (2002). Development of polymer film dosage forms of lidocaine for buccal administration: II. Comparison of preparation methods. Journal of Pharmaceutical Sciences, 91(11), 2424-2432.
25. Peh, K., & Wong, C. (1999). Polymeric films as vehicle for buccal delivery: swelling, mechanical, and bioadhesive properties. Journal of Pharmacy and Pharmaceutical Sciences, 2(2), 53-61.
26. Perioli, L., Ambrogi, V., Angelici, A., Ricci, M., Giovagnoli, S., Capuccella, M., & Rossi, C. (2004). Development of mucoadhesive patches for buccal administration of ibuprofen. Journal of Controlled Release, 99(1),73-82.
27. Qvist, M., Hoeck, U., Kreilgaard, B., Madsen, F., & Frokjaer, S. (2002). Release of chemical permeation enhancers from drug-in-adhesive transdermal patches. International Journal of Pharmaceutics, 231, 253-263.
28. Rathbone, M. (1996). Oral Mucosal Drug Delivery; Marcel Dekker, Inc.: 270 Madison Avenue, New York, USA.
29. Repka, M., Gutta, K., Prodduturi, S., Munjal, M., & Stodghill, S. (2005). Characterization of cellulosic hot-melt extruded films containing lidocaine. European Journal of Pharmaceutics and Biopharmaceutics, 59(1), 189-196.
30. Senel, S., Kremer, M., Kas, S., Wertz, P., Hincal, A., & Squier, C. (2000). Enhancing effect of chitosan on peptide drug delivery across buccal mucosa. Biomaterials, 21, 2067-2071.
31. Shargel, L., & Yu, A. (1993). Applied Biopharmaceutics and Pharmacokinetics, (3rd Ed.); Appleton and Lange: Norwalk, Connecticut, USA.
32. Shin, S., Kim, J., & Oh, I. (2000). Mucoadhesive and physicochemical characterization of carbopol-poloxamer gels containing triamcinolone acetonide. Drug Development and Industrial Pharmacy, 26(3), 307-312.
33. Shojaei, A. (1998). Buccal mucosa as a route for systemic drug delivery: a review. Journal of Pharmacy and Pharmaceutical Sciences, 1(1), 15-30.
34. Shojaei, A., Chang, R., Guo, X., Burnside, B., & Couch, R. (2001). Systemic drug delivery via the buccal mucosal route. Pharmaceutical Technology, 6, 70-80.
35. Shojaei, A., Zhou, S., & Li, X. Transbuccal delivery of acyclovir (II): Feasibility, system design, and in vitro permeation studies. Journal of Pharmacy and Pharmaceutical Science, 1(2), 66-73.
36. Singla, A., Chawla, M., & Singh, A. (2000). Potential applications of Carbomer in oral mucoadhesive controlled drug delivery system: review. Drug Development and Industrial Pharmacy, 26(9), 913-924.
37. Stott, P., Williams, A., & Barry, B. (1998). Transdermal delivery from eutectic systems: enhanced permeation of a model drug, ibuprofen. Journal of Controlled Release, 50, 297-308.
38. Turunen, T., Urtti, A., Paronen, P., Audus, K., & Rytting, J. (1994). Effect of some penetration enhancers on epithelial membrane lipid domains: evidence from fluorescence spectroscopy studies. Pharmaceutical Research, 11(2), 288-294.
39. Veuillez, F., Kalia, Y., Jacques, Y., Deshusses, J., & Buri, P. (2001). Factors and strategies for improving buccal absorption of peptides. European Journal of Pharmaceutics and Biopharmaceutics, 51, 93-109.
40. Xiang, J., Fang, X., & Li, X. (2002). Transbuccal delivery of 2′,3′-dideoxycytidine: in vitro permeation study and histological investigation. International Journal of Pharmaceutics, 231, 57-66.
41. Yahagi, R., Onishi, H., & Machida, Y. (1999). Preparation and evaluation of double-phased mucoadhesive suppositories of lidocaine utilizing carbopol and white beeswax. Journal of Controlled Release, 61, 1-8.