Modulatory effects of luteolin on osteoblastic function and inflammatory mediators in osteoblastic MC3T3-E1 cells

Cell Biology International

Volumn 31, Issue 9, 2007, Pages 870-877

  Choi, Eun Mi ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Luteolin; Osteoblastic MC3T3 E1 cells

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN; CYCLOHEXIMIDE; CYTOKINE; ESTROGEN; INTERLEUKIN 6; LINSIDOMINE; LUTEOLIN; NITRIC OXIDE; OSTEOCALCIN; PROSTAGLANDIN E2; TAMOXIFEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRAIN 3T3; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ESTROGEN ACTIVITY; INFLAMMATION; MOUSE; NONHUMAN; OSTEOBLAST; OXIDATIVE STRESS; PROSTAGLANDIN SYNTHESIS; PROTEIN SECRETION;

ACETONITRILES; ALKALINE PHOSPHATASE; ANIMALS; CELL LINE; COLLAGEN; DINOPROSTONE; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LUTEOLIN; MICE; MORPHOLINES; NITRIC OXIDE; OSTEOBLASTS; OSTEOCALCIN; PHYTOESTROGENS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34249301361     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2007.01.038     Document Type: Article

References (48)

1. An J., Tzagarakis-Foster C., Scharschmidt T.C., Lomri N., and Leitman D.C. Estrogen receptor b-selective transcriptional activity and recruitment of coregulators by phytoestrogens. The Journal of Biological Chemistry 276 (2001) 17808-17814
2. Anderson J.J.B., and Garner S.C. Phytoestrogens and bone. Bailliere's Clinical Endocrinology and Metabolism 12 (1998) 543-557
3. Bellows C.G., Aubin J.E., and Heersche J.N.M. Initiation and progression of mineralization of bone nodules formed in vitro-the role of alkaline-phosphatase and organic phosphate. Bone and Mineral 14 (1991) 27-40
4. Chen X.W., Garner S.C., Quarles L.D., and Anderson J.J.B. Effects of genistein on expression cell of bone markers during MC3T3-E1 osteoblastic differentiation. The Journal of Nutritional Biochemistry 14 (2003) 342-349
5. Choi E.M. The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells. Biochemical Pharmacology 70 3 (2005) 363-368
6. Crow J.P., and Ischiropoulos H. Detection and quantitation of nitrotyrosine residues in proteins: in vivo marker of peroxynitrite. Methods in Enzymology 269 (1996) 185-194
7. Da Rocha F.A.C., and Brum-Fernandes A.J. Evidence that peroxynitrite affects human osteoblast proliferation and differentiation. Journal of Bone and Mineral Research 17 (2002) 434
8. Damiens C., Fortun Y., Charrier C., Heymann D., and Padrines M. Modulation by soluble factors of gelatinase activities by osteoblastic cells. Cytokine 12 (2000) 1727-1731
9. Eldridge A.L., Haytowitz D.B., Bhagwat S., Gebhardt S.E., Holden J.M., Beecher G.R., et al. Flavonoid content of vegetables: the USDA's flavonoid database (2003), Human Nutrition Research Center, ARS, USDA
10. Franchimont N., Rydziel S., and Canalis E. Interleukin 6 is autoregulated by transcriptional mechanisms in cultures of rat osteoblastic cells. The Journal of Clinical Investigation 100 (1997) 1797-1803
11. Garg A.K., and Aggarwal B.B. Reactive oxygen intermediates in TNF signaling. Molecular Immunology 39 (2002) 509-517
12. Girasole G., Jilka R.L., Passeri G., Boswell S., Williams D.C., and Manolagas S. 17β-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens. The Journal of Clinical Investigation 89 (1992) 883-891
13. Gunberg C.M., and Nishimoto S.K. Vitamin K-dependent proteins of bone and cartilage. In: Seibel M.J., Robins S.P., and Bilezikian J.P. (Eds). Dynamics of bone and cartilage metabolism (1999), Academic Press, San Diego 45-53
14. Halliwell B., Zhao K., and Whiteman M. Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good. Free Radical Research 31 (1999) 651-669
15. Husain S.R., Cillard J., and Cillard P. Hydroxyl radical scavenging activity of flavonoids. Phytochemistry 26 (1987) 2489-2492
16. Ikegami A., Inoue S., Hosoi T., Mizuno Y., Nakamura T., Ouchi Y., et al. Immunohistochemical detection and northern blot analysis of estrogen-receptor in osteoblastic cells. Journal of Bone and Mineral Research 8 (1993) 1103-1109
17. Ise R., Han D., Takahashi Y., Terasaka S., Inoue A., Tanji M., et al. Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray. FEBS Letters 579 (2005) 1732-1740
18. Kanno S., Anuradha C.D., and Hirano S. Localization of zinc after in vitro mineralization in osteoblastic cells. Biological Trace Element Research 83 (2001) 39-47
19. Kassem M., Harris S., Spelsberg T.C., and Riggs B.L. Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high level of estrogen receptors. Journal of Bone and Mineral Research 11 (1996) 193-199
20. Kleinerman E.S., Lachman L.B., Knowles R.D., Snyderman R., and Cianciolo G.J. A synthetic peptide homologous to the envelope proteins of retroviruses inhibits monocyte-mediated killing by inactivating interleukin 1. Journal of Immunology 139 (1987) 2329-2337
21. Kodama H.A., Suda Y., Kasai H., and Yamamoto S. Establishment of a clonal osteogenic cell line from newborn mouse calvaria. Japanese Journal of Oral Biology 23 (1981) 899-901
22. Kotake S., Sato K., Kim K.J., Takahash N., Udagawa N., Nakamura I., et al. Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation. Journal of Bone and Mineral Research 11 (1996) 88-95
23. Le Bail J.C., Varnat F., Nicolas J.C., and Habrioux G. Estrogenic and antiproliferative activities on MCF-7 human breast cancer cells by flavonoids. Cancer Letter 130 (1998) 209-216
24. Lee K.H., and Choi E.M. Biochanin A stimulates osteoblastic differentiation and inhibits hydrogen peroxide-induced production of inflammatory mediators in MC3T3-E1 cells. Biological & Pharmaceutical Bulletin 28 10 (2005) 1948-1953
25. Miyake M., Arai N., Ushio S., Iwaki K., Ikeda M., and Kurimoto M. Promoting effect of kaempferol on the differentiation and mineralization of murine pre-osteoblastic cell line MC3T3-E1. Bioscience, Biotechnology, and Biochemistry 67 6 (2003) 1199-1205
26. Mizutani K., Ikeda K., Kawai Y., and Yamori Y. Resveratrol stimulates the proliferation and differentiation of osteoblastic MC3T3-E1 cells. Biochemical and Biophysical Research Communications 253 (1998) 859-863
27. Moncad S., Palmer R.M.J., and Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacological Reviews 43 (1991) 109-142
28. Nagao M., Morita N., Yahagi T., Shimizu M., Kuroyanagi M., Fukuoka M., et al. Mutagenicities of 61 flavonoids and 11 related compounds. Environmental Mutagenesis 3 (1981) 401-419
29. Parfitt A.M. Bone remodeling and bone loss-understanding the pathophysiology of osteoporosis. Clinical Obstetrics and Gynecology 30 (1987) 789-811
30. Pryor W.A., and Squadrito G.L. The chemistry of peroxynitrite: a product from the reaction of nitric oxide and superoxide. The American Journal of Physiology 268 (1995) L699-L722
31. Rodan G.A. Introduction to bone biology. Bone 13 (1992) S3-S6
32. Roggia C., Gao Y., Cenci S., Weitzmann M.N., Toraldo G., Isaia G., et al. Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proceedings of the National Academy of Sciences of the United States of America 98 (2001) 13960-13965
33. Routledge E.J., White R., Parker M.G., and Sumpter X.X. Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) α and ERβ. The Journal of Biological Chemistry 276 (2000) 35986-35993
34. Samejima K., Kanazawa K., Ashida H., and Danno G.J. Luteolin: a strong antimutagen against dietary carcinogen, Trp-P-2, in peppermint, sage, and thyme. Journal of Agricultural and Food Chemistry 43 (1995) 410-414
35. Stein G.S., and Lian J.B. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype. Endocrine Reviews 1 (1993) 424-442
36. Stein G.S., Lian J.B., and Owen T.A. Relationship of cell-growth to the regulation of tissue-specific gene-expression during osteoblast differentiation. The FASEB Journal 4 (1990) 3111-3123
37. Sugimoto E., and Yamaguchi M. Anabolic effect of genistein in osteoblastic MC3T3-E1 cells. International Journal of Molecular Medicine 5 5 (2000) 515-520
38. Sugimoto E., and Yamaguchi M. Stimulatory effect of daidzein in osteoblastic MC3T3-E1 cells. Biochemical Pharmacology 59 (2000) 471-475
39. 2-derived free radicals treated fibronectin substratum reduces the bone nodule formation of rat calvarial osteoblast. Mechanisms of Ageing and Development 98 (1995) 177-187
40. Tyner S.D., Venkatachalam S., Choi J., Jones S., Ghebranious N., Igelmann H., et al. p53 mutant mice that display early aging-associated phenotypes. Nature 415 (2002) 45-53
41. Uchida M., Shima M., Shimoaka T., Fujieda A., Obara K., Suzuki H., et al. Regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) by bone resorptive factors in osteoblastic cells. Journal of Cellular Physiology 185 (2000) 207-214
42. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women's Health Initiative randomized controlled trial. Journal of the American Medical Association 288 (2002) 321-333
43. Xagorari A., Papapetropoulos A., Mauromatis A., Economou M., Fotsis T., and Roussos C. Luteolin inhibits an endotoxin-stimulated phosphorylation cascade and pro-inflammatory cytokine production in macrophages. Journal of Pharmacology and Experimental Therapeutics 296 (2001) 181-187
44. Xagorari A., Roussos C., and Papapetropoulos A. Inhibition of LPS-stimulated pathways in macrophages by the flavonoid luteolin. British Journal of Pharmacology 136 (2002) 1058-1064
45. Yamaguchi M., and Gao Y.H. Anabolic effect of genistein on bone metabolism in the femoral-metaphyseal tissues of elderly rats is inhibited by the anti-estrogen tamoxifen. Research in Experimental Medicine 197 (1997) 101-107
46. Yamamoto H., Sakakibara J., Nagatsu A., and Sekiya K. Inhibitors of arachidonate lipoxygenase from defatted perilla seed. Journal of Agricultural and Food Chemistry 46 (1998) 862-865
47. Yasukawa K., Takido M., Takeuchi M., and Nakagawa S. Effect of chemical constituents from plants on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. Chemical & Pharmaceutical Bulletin 37 (1989) 1071-1073
48. Yoshida H., Teramoto T., Ikeda K., and Yamori Y. Glycitein effect on suppressing the proliferation and stimulating the differentiation of osteoblastic MC3T3-E1 cells. Bioscience, Biotechnology. Biochemistry 65 5 (2001) 1211-1213