Wnts: up-and-coming at the synapse

Trends in Neurosciences

Volumn 30, Issue 6, 2007, Pages 268-275

  Speese, Sean D ^a   Budnik, Vivian ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CALCIUM; FRIZZLED PROTEIN; LITHIUM CHLORIDE; MESSENGER RNA; NICOTINIC RECEPTOR; PROTEIN CDC42; WNT PROTEIN;

ALZHEIMER DISEASE; BRAIN NERVE CELL; CELL DIFFERENTIATION; CELL MATURATION; DENDRITIC CELL; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTIC MEMBRANE;

ANIMALS; BASE SEQUENCE; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; NERVOUS SYSTEM; NEURONAL PLASTICITY; SEQUENCE HOMOLOGY, NUCLEIC ACID; SIGNAL TRANSDUCTION; SYNAPSES; WNT PROTEINS;

EID: 34249284178     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tins.2007.04.003     Document Type: Review

References (55)

1. Li F., et al. Vital elements of the Wnt-Frizzled signaling pathway in the nervous system. Curr. Neurovasc. Res. 2 (2005) 331-340
2. Ciani L., and Salinas P.C. WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nat. Rev. Neurosci. 6 (2005) 351-362
3. Caricasole A., et al. Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology. Biosci. Rep. 25 (2005) 309-327
4. Terstappen G.C., et al. The Wnt signaling pathway as a target for the treatment of neurodegenerative disorders. IDrugs 9 (2006) 35-38
5. Wodarz A., and Nusse R. Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14 (1998) 59-88
6. Takeichi M. The cadherin superfamily in neuronal connections and interactions. Nat. Rev. Neurosci. 8 (2007) 11-20
7. Salinas P.C., and Price S.R. Cadherins and catenins in synapse development. Curr. Opin. Neurobiol. 15 (2005) 73-80
8. Salinas P.C., and Nusse R. Regional expression of the Wnt-3 gene in the developing mouse forebrain in relationship to diencephalic neuromeres. Mech. Dev. 39 (1992) 151-160
9. Lucas F.R., and Salinas P.C. WNT-7a induces axonal remodeling and increases synapsin I levels in cerebellar neurons. Dev. Biol. 192 (1997) 31-44
10. Hall A.C., et al. Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling. Cell 100 (2000) 525-535
11. Hamori J., and Somogyi J. Differentiation of cerebellar mossy fiber synapses in the rat: a quantitative electron microscope study. J. Comp. Neurol. 220 (1983) 365-377
12. Ahmad-Annuar A., et al. Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release. J. Cell Biol. 174 (2006) 127-139
13. Krylova O., et al. WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons. Neuron 35 (2002) 1043-1056
14. Krylova O., et al. Dishevelled-1 regulates microtubule stability: a new function mediated by glycogen synthase kinase-3β. J. Cell Biol. 151 (2000) 83-94
15. Ciani L., et al. A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules. J. Cell Biol. 164 (2004) 243-253
16. Lucas F.R., et al. Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium. J. Cell Sci. 111 (1998) 1351-1361
17. Halpain S., and Dehmelt L. The MAP1 family of microtubule-associated proteins. Genome Biol. 7 (2006) 224
18. Goold R.G., and Gordon-Weeks P.R. Glycogen synthase kinase 3β and the regulation of axon growth. Biochem. Soc. Trans. 32 (2004) 809-811
19. Rosso S.B., et al. Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat. Neurosci. 8 (2005) 34-42
20. Mathew D., et al. Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science 310 (2005) 1344-1347
21. Kummer T.T., et al. Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost. Curr. Opin. Neurobiol. 16 (2006) 74-82
22. Madhavan R., and Peng H.B. Molecular regulation of postsynaptic differentiation at the neuromuscular junction. IUBMB Life 57 (2005) 719-730
23. McMahan U.J. The agrin hypothesis. Cold Spring Harb. Symp. Quant. Biol. 55 (1990) 407-418
24. Luo Z.G., et al. Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1. Neuron 35 (2002) 489-505
25. Kim C.H., et al. Regulation of MuSK expression by a novel signaling pathway. J. Biol. Chem. 278 (2003) 38522-38527
26. Wang J., et al. Regulation of acetylcholine receptor clustering by the tumor suppressor APC. Nat. Neurosci. 6 (2003) 1017-1018
27. Temburni M.K., et al. Neuronal nicotinic synapse assembly requires the adenomatous polyposis coli tumor suppressor protein. J. Neurosci. 24 (2004) 6776-6784
28. Dreier L., et al. LIN-23-mediated degradation of β-catenin regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Neuron 46 (2005) 51-64
29. De Ferrari G.V., and Moon R.T. The ups and downs of Wnt signaling in prevalent neurological disorders. Oncogene 25 (2006) 7545-7553
30. Ferrero A., et al. Vertex 17 (2006) 165-171
31. Chen J., et al. Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation. J. Biol. Chem. 281 (2006) 11910-11916
32. Huang E.P. Synaptic plasticity: going through phases with LTP. Curr. Biol. 8 (1998) R350-R352
33. Pittenger C., and Kandel E. A genetic switch for long-term memory. C. R. Acad. Sci. III 321 (1998) 91-96
34. Hsieh J.C., et al. A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature 398 (1999) 431-436
35. Packard M., et al. The Drosophila Wnt, wingless, provides an essential signal for pre- and postsynaptic differentiation. Cell 111 (2002) 319-330
36. Ataman B., et al. Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 7841-7846
37. Roos J., et al. Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron 26 (2000) 371-382
38. Ruiz-Canada C., et al. New synaptic bouton formation is disrupted by misregulation of microtubule stability in a PKC mutants. Neuron 42 (2004) 567-580
39. Franco B., et al. Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila. J. Neurosci. 24 (2004) 6573-6577
40. Gogel S., et al. The Drosophila microtubule associated protein Futsch is phosphorylated by Shaggy/Zeste-white 3 at an homologous GSK3β phosphorylation site in MAP1B. Mol. Cell. Neurosci. 33 (2006) 188-199
41. Gomez-Ospina N., et al. The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor. Cell 127 (2006) 591-606
42. Lin S.Y., et al. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat. Cell Biol. 3 (2001) 802-808
43. Baron M., et al. Multiple levels of Notch signal regulation. Mol. Membr. Biol. 19 (2002) 27-38
44. Hoogenraad C.C., et al. GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Nat. Neurosci. 8 (2005) 906-915
45. Bredt D.S., and Nicoll R.A. AMPA receptor trafficking at excitatory synapses. Neuron 40 (2003) 361-379
46. Burette A., et al. Characterization of glutamate receptor interacting protein-immunopositive neurons in cerebellum and cerebral cortex of the albino rat. J. Comp. Neurol. 411 (1999) 601-612
47. Wu C.H., and Nusse R. Ligand receptor interactions in the Wnt signaling pathway in Drosophila. J. Biol. Chem. 277 (2002) 41762-41769
48. Takada R., et al. Analysis of combinatorial effects of Wnts and Frizzleds on β-catenin/armadillo stabilization and Dishevelled phosphorylation. Genes Cells 10 (2005) 919-928
49. Cadigan K.M., and Liu Y.I. Wnt signaling: complexity at the surface. J. Cell Sci. 119 (2006) 395-402
50. Wu J., et al. Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity. PLoS Biol. 2 (2004) E158
51. Lu W., et al. Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell 119 (2004) 97-108
52. Yoshikawa S., et al. Wnt-mediated axon guidance through the Drosophila Derailed receptor. Nature 422 (2003) 583-588
53. Prokop A. Organization of the efferent system and structure of neuromuscular junctions in Drosophila. Int. Rev. Neurobiol. 75 (2006) 71-90
54. Griffith L.C., and Budnik V. Plasticity and second messengers during synapse development. Int. Rev. Neurobiol. 75 (2006) 237-265
55. Li X., and Cao X. BMP signaling and HOX transcription factors in limb development. Front. Biosci. 8 (2003) s805-s812