-
1
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K: The future of genetic studies of complex human diseases. Science 1996;273:1516-1517.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
2
-
-
27244451809
-
-
Maraganore DM, de Andrade M, Lesnick TG, Strain KJ, Farrer MJ, Rocca, WA, Pant PVK, Frazer KA, Cox DR, Ballinger DG: High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet 2005;77:685-693.
-
Maraganore DM, de Andrade M, Lesnick TG, Strain KJ, Farrer MJ, Rocca, WA, Pant PVK, Frazer KA, Cox DR, Ballinger DG: High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet 2005;77:685-693.
-
-
-
-
3
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, Rioux, JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO, Schumm LP, Lee AT, Gregersen PK, Barmada MM, Rotter JI, Nicolae DL, Cho JH: A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006;314:1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
4
-
-
33745240931
-
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
-
Smyth DJ, Cooper JD, Bailey R, Field S, Burren O, Smink LJ, Guja C, Ionescu-Tirgoviste C, Widmer B, Dunger DB, Savage DA, Walker NM, Clayton DG, Todd JA: A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nature Genet 2006;38:617-619.
-
(2006)
Nature Genet
, vol.38
, pp. 617-619
-
-
Smyth, D.J.1
Cooper, J.D.2
Bailey, R.3
Field, S.4
Burren, O.5
Smink, L.J.6
Guja, C.7
Ionescu-Tirgoviste, C.8
Widmer, B.9
Dunger, D.B.10
Savage, D.A.11
Walker, N.M.12
Clayton, D.G.13
Todd, J.A.14
-
5
-
-
0142063079
-
Polygenic inheritance of breast cancer: Implications for design of association studies
-
Antoniou AC, Easton DF: Polygenic inheritance of breast cancer: Implications for design of association studies. Genet Epidemiol 2003;25:190-202.
-
(2003)
Genet Epidemiol
, vol.25
, pp. 190-202
-
-
Antoniou, A.C.1
Easton, D.F.2
-
6
-
-
33746491583
-
The Breast Cancer Susceptibility Collaboration (UK), Rahman N: ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility
-
Renwick A, Thompson D, Seal S, Kelly P, Chagtai T, Ahmed M, North B, Jayatilake H, Barfoot R, Spanova K, McGuffog L, Evans DG, Eccles D, Easton DF, Stratton MR, The Breast Cancer Susceptibility Collaboration (UK), Rahman N: ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility Nature Genet 2006;38:873-875.
-
(2006)
Nature Genet
, vol.38
, pp. 873-875
-
-
Renwick, A.1
Thompson, D.2
Seal, S.3
Kelly, P.4
Chagtai, T.5
Ahmed, M.6
North, B.7
Jayatilake, H.8
Barfoot, R.9
Spanova, K.10
McGuffog, L.11
Evans, D.G.12
Eccles, D.13
Easton, D.F.14
Stratton, M.R.15
-
7
-
-
22844449221
-
Genomic screening and replication using the same data set in family-based association testing
-
Van Steen K, McQueen MB, Herbert A, Raby B, Lyon H, DeMeo DL, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman EK, Laird NM, Weiss ST, Lange C: Genomic screening and replication using the same data set in family-based association testing. Nature Genet 2005;37:683-691.
-
(2005)
Nature Genet
, vol.37
, pp. 683-691
-
-
Van Steen, K.1
McQueen, M.B.2
Herbert, A.3
Raby, B.4
Lyon, H.5
DeMeo, D.L.6
Murphy, A.7
Su, J.8
Datta, S.9
Rosenow, C.10
Christman, M.11
Silverman, E.K.12
Laird, N.M.13
Weiss, S.T.14
Lange, C.15
-
8
-
-
33750376475
-
Perils and pitfalls of permutation tests for distinguishing the effects of neighbouring polymorphisms
-
Biernacka JM, Cordell HJ: Perils and pitfalls of permutation tests for distinguishing the effects of neighbouring polymorphisms. Genet Epidemiol 2006;30:582-589.
-
(2006)
Genet Epidemiol
, vol.30
, pp. 582-589
-
-
Biernacka, J.M.1
Cordell, H.J.2
-
9
-
-
1842483890
-
Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, gene-gene and gene-environment interactions, and parent-of-origin effects
-
Cordell HJ, Barratt BJ, Clayton DG: Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, gene-gene and gene-environment interactions, and parent-of-origin effects. Genet Epidemiol 2004;26:167-185.
-
(2004)
Genet Epidemiol
, vol.26
, pp. 167-185
-
-
Cordell, H.J.1
Barratt, B.J.2
Clayton, D.G.3
-
10
-
-
30344454575
-
Analysis of binary traits: Testing association in the presence of linkage
-
Jonasdottir G, Palmgren J, Humphreys K: Analysis of binary traits: Testing association in the presence of linkage. BMC Genet 2005;6:S92.
-
(2005)
BMC Genet
, vol.6
-
-
Jonasdottir, G.1
Palmgren, J.2
Humphreys, K.3
-
11
-
-
20544475886
-
Complex trait mapping in isolated populations: Are specific statistical methods required?
-
Bourgain C, Genin E: Complex trait mapping in isolated populations: Are specific statistical methods required? Eur J Hum Genet 2005;13:698-706.
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 698-706
-
-
Bourgain, C.1
Genin, E.2
-
12
-
-
21344447945
-
Comparison of population- and family-based methods for genetic association analysis in the presence of interacting loci
-
Howson JMM, Barratt BJ, Todd JA, Cordell HJ: Comparison of population- and family-based methods for genetic association analysis in the presence of interacting loci. Genet Epidemiol 2005;29:51-67.
-
(2005)
Genet Epidemiol
, vol.29
, pp. 51-67
-
-
Howson, J.M.M.1
Barratt, B.J.2
Todd, J.A.3
Cordell, H.J.4
-
13
-
-
26644438107
-
Genetic epidemiology 6 - population-based family studies in genetic epidemiology
-
Hopper JL, Bishop DT, Easton DF: Genetic epidemiology 6 - population-based family studies in genetic epidemiology. Lancet 2005;366:1397-1406.
-
(2005)
Lancet
, vol.366
, pp. 1397-1406
-
-
Hopper, J.L.1
Bishop, D.T.2
Easton, D.F.3
-
14
-
-
27944502545
-
Familial risk of cancer shortly after diagnosis of the first familial tumor
-
Bermejo JL, Hemminki K: Familial risk of cancer shortly after diagnosis of the first familial tumor. J Nat Cancer Inst 2005;97:1575-1579.
-
(2005)
J Nat Cancer Inst
, vol.97
, pp. 1575-1579
-
-
Bermejo, J.L.1
Hemminki, K.2
-
16
-
-
0036807194
-
Genetic and Environmental Factors in Health-related Behaviors: Studies on Finnish Twins and Twin Families
-
Kaprio J, Pulkkinen L, Rose RJ: Genetic and Environmental Factors in Health-related Behaviors: Studies on Finnish Twins and Twin Families. Twin Res 2002;5:366-371.
-
(2002)
Twin Res
, vol.5
, pp. 366-371
-
-
Kaprio, J.1
Pulkkinen, L.2
Rose, R.J.3
-
17
-
-
4444227337
-
Genetic and environmental factors in breakfast eating patterns
-
Keski-Rahkonen A, Viken RJ, Kaprio J, Rissanen A, Rose RJ: Genetic and environmental factors in breakfast eating patterns. Behav Genet 2004;34:503-514.
-
(2004)
Behav Genet
, vol.34
, pp. 503-514
-
-
Keski-Rahkonen, A.1
Viken, R.J.2
Kaprio, J.3
Rissanen, A.4
Rose, R.J.5
-
18
-
-
33644874530
-
Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population
-
Tobin MD, Raleigh SM, Newhouse S, Braund P, Bodycote C, Ogleby J, Cross D, Gracey J, Hayes S, Smith T, Ridge C, Caulfield M, Sheehan NA, Munroe PB, Burton PR, Samani NJ: Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population. Circulation 2005;112:3423-3429.
-
(2005)
Circulation
, vol.112
, pp. 3423-3429
-
-
Tobin, M.D.1
Raleigh, S.M.2
Newhouse, S.3
Braund, P.4
Bodycote, C.5
Ogleby, J.6
Cross, D.7
Gracey, J.8
Hayes, S.9
Smith, T.10
Ridge, C.11
Caulfield, M.12
Sheehan, N.A.13
Munroe, P.B.14
Burton, P.R.15
Samani, N.J.16
-
19
-
-
33749621790
-
The biobank of the Norwegian mother and child cohort Study: A resource for the next 100 years
-
Ronningen KS, Paltiel L, Meltzer HM, Nordhagen R, Lie KK, Hovengen R, Haugen M, Nystad W, Magnus P, Hoppin JA: The biobank of the Norwegian mother and child cohort Study: A resource for the next 100 years. Eur J Epidemiol 2006;21:619-625.
-
(2006)
Eur J Epidemiol
, vol.21
, pp. 619-625
-
-
Ronningen, K.S.1
Paltiel, L.2
Meltzer, H.M.3
Nordhagen, R.4
Lie, K.K.5
Hovengen, R.6
Haugen, M.7
Nystad, W.8
Magnus, P.9
Hoppin, J.A.10
-
20
-
-
33749620329
-
-
Smith BH, Campbell H, Blackwood D, Connell J, Connor M, Deary IJ, Anna F Dominiczak AF, Fitzpatrick B, Ford I, Jackson C, Haddow G, Kerr S, Lindsay R, McGilchrist M, Morton R, Murray G, Palmer CNA, Pell JP, Ralston SH, St Clair D, Sullivan F, Watt G, Wolf R, Wright A, Porteous D, Morris AD: Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability. BMC Med Genet 2006;7:Art. No. 74.
-
Smith BH, Campbell H, Blackwood D, Connell J, Connor M, Deary IJ, Anna F Dominiczak AF, Fitzpatrick B, Ford I, Jackson C, Haddow G, Kerr S, Lindsay R, McGilchrist M, Morton R, Murray G, Palmer CNA, Pell JP, Ralston SH, St Clair D, Sullivan F, Watt G, Wolf R, Wright A, Porteous D, Morris AD: Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability. BMC Med Genet 2006;7:Art. No. 74.
-
-
-
-
21
-
-
33745078080
-
A population-based assessment of the familial component of chronic kidney disease mortality
-
Goldfarb-Rumyantzev AS, Cheung AK, Habib AN, Wang BJ, Lin S, Baird BC, Naiman N, Cannon-Albright L: A population-based assessment of the familial component of chronic kidney disease mortality. Am J Nephrol 2006;26:142-148.
-
(2006)
Am J Nephrol
, vol.26
, pp. 142-148
-
-
Goldfarb-Rumyantzev, A.S.1
Cheung, A.K.2
Habib, A.N.3
Wang, B.J.4
Lin, S.5
Baird, B.C.6
Naiman, N.7
Cannon-Albright, L.8
-
23
-
-
24344447526
-
Identification and study of Utah pseudo-isolate populations - Prospects for gene identification
-
Cannon-Albright LA, Farnham JM, Thomas A, Camp NJ: Identification and study of Utah pseudo-isolate populations - Prospects for gene identification. Am J Med Genet 2005;137A:269-275.
-
(2005)
Am J Med Genet
, vol.137 A
, pp. 269-275
-
-
Cannon-Albright, L.A.1
Farnham, J.M.2
Thomas, A.3
Camp, N.J.4
-
24
-
-
33750539106
-
Localization of a prostate cancer predisposition gene to an 880-kb region on chromosome 22q12.3 in Utah high-risk pedigrees
-
Camp NJ, Farnham JM, Cannon-Albright LA: Localization of a prostate cancer predisposition gene to an 880-kb region on chromosome 22q12.3 in Utah high-risk pedigrees. Cancer Res 2006;66:10205-10212.
-
(2006)
Cancer Res
, vol.66
, pp. 10205-10212
-
-
Camp, N.J.1
Farnham, J.M.2
Cannon-Albright, L.A.3
-
25
-
-
14844293461
-
Dissecting the genetic etiology of major depressive disorder using linkage analysis
-
Camp NJ, Cannon-Albright LA: Dissecting the genetic etiology of major depressive disorder using linkage analysis Trends Mol Med 2005;11:138-144.
-
(2005)
Trends Mol Med
, vol.11
, pp. 138-144
-
-
Camp, N.J.1
Cannon-Albright, L.A.2
-
26
-
-
34249000185
-
-
for the British Heart Foundation Family Heart Study Research Group:, Eur J Hum Genet advance online publication, December 6
-
Nsengimana J, Samani NJ, Hall AS, Balmforth AJ, Mangino M, Yuldasheva N, Maqbool A, Braund P, Burton P, Bishop DT, Ball SG, Barrett JH for the British Heart Foundation Family Heart Study Research Group: Enhanced linkage of a locus on chromosome 2 to premature coronary artery disease in the absence of hypercholesterolemia. Eur J Hum Genet advance online publication, December 6, 2006.
-
(2006)
Enhanced linkage of a locus on chromosome 2 to premature coronary artery disease in the absence of hypercholesterolemia
-
-
Nsengimana, J.1
Samani, N.J.2
Hall, A.S.3
Balmforth, A.J.4
Mangino, M.5
Yuldasheva, N.6
Maqbool, A.7
Braund, P.8
Burton, P.9
Bishop, D.T.10
Ball, S.G.11
Barrett, J.H.12
-
27
-
-
34249899967
-
Structured incorporation of prior information in identification problems
-
in press
-
Egeland T, Sheehan NA: Structured incorporation of prior information in identification problems. Ann Hum Genet 2007, in press.
-
(2007)
Ann Hum Genet
-
-
Egeland, T.1
Sheehan, N.A.2
-
28
-
-
33646887766
-
Online system for faster multipoint linkage analysis via parallel execution on thousands of personal computers
-
Silberstein M, Tzemach A, Dovgolevsky N, Fishelson M, Schuster A, Geiger D: Online system for faster multipoint linkage analysis via parallel execution on thousands of personal computers. Am J Hum Genet 2006;78:922-935.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 922-935
-
-
Silberstein, M.1
Tzemach, A.2
Dovgolevsky, N.3
Fishelson, M.4
Schuster, A.5
Geiger, D.6
-
29
-
-
33947164324
-
Fuzzy p-values in latent variable problems
-
in press
-
Thompson EA, Geyer CJ: Fuzzy p-values in latent variable problems. Biometrika 2007, in press.
-
(2007)
Biometrika
-
-
Thompson, E.A.1
Geyer, C.J.2
-
30
-
-
34249052984
-
Uncertainty in Inheritance: Assessing evidence for linkage. Paper presented at the Third University of Washington Biostatistics Symposium: Nov 2005
-
Technical report No. 498, Department of Statistics, University of Washington
-
Thompson EA: Uncertainty in Inheritance: Assessing evidence for linkage. Paper presented at the Third University of Washington Biostatistics Symposium: Nov 2005. Technical report No. 498, Department of Statistics, University of Washington, 2006. (http://www.stat.washington.edu/www/research/reports/2006/ tr498.pdf)
-
(2006)
-
-
Thompson, E.A.1
-
31
-
-
33845336152
-
The balance between heritable and environmental aetiology of human disease
-
Hemminki K, Bermejo JL, Forsti A: The balance between heritable and environmental aetiology of human disease. Nat Rev Genet 2006;7:958-965.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 958-965
-
-
Hemminki, K.1
Bermejo, J.L.2
Forsti, A.3
|