EADock: Docking of small molecules into protein active sites with a multiobjective evolutionary optimization

Proteins: Structure, Function and Genetics

Volumn 67, Issue 4, 2007, Pages 1010-1025

  Grosdidier, Aurélien ^a   Zoete, Vincent ^a   Michielin, Olivier ^a  

^a SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

EADock; Evolutionary algorithms; Rational drug design; Small ligand docking

Indexed keywords

DOCKING PROTEIN; LIGAND; PENTAPEPTIDE; VITRONECTIN RECEPTOR;

ARTICLE; BINDING AFFINITY; CLUSTER ANALYSIS; COMPUTER PROGRAM; CRYSTAL STRUCTURE; CRYSTALLIZATION; EVOLUTIONARY ALGORITHM; MOLECULE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; VALIDATION PROCESS;

ALGORITHMS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; EVOLUTION, MOLECULAR; LIGANDS; MODELS, MOLECULAR; PROBABILITY; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS;

EID: 34248562742     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21367     Document Type: Article

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