-
1
-
-
0033594737
-
Age-associated changes in rhesus CNS composition identified by MRI
-
Andersen AH, Zhang Z, Zhang M, Gash DM, Avison MJ. 1999. Age-associated changes in rhesus CNS composition identified by MRI. Brain Res 829:90-98.
-
(1999)
Brain Res
, vol.829
, pp. 90-98
-
-
Andersen, A.H.1
Zhang, Z.2
Zhang, M.3
Gash, D.M.4
Avison, M.J.5
-
2
-
-
0023882241
-
Distribution and morphological characteristics of dopamine-immunoreactive neurone in the midbrain of the squirrel monkey (Saimiri sciureus)
-
Arsenault MY, Parent A, Seguela P, Descarries L. 1988. Distribution and morphological characteristics of dopamine-immunoreactive neurone in the midbrain of the squirrel monkey (Saimiri sciureus). J Comp Neurol 267:489-506.
-
(1988)
J Comp Neurol
, vol.267
, pp. 489-506
-
-
Arsenault, M.Y.1
Parent, A.2
Seguela, P.3
Descarries, L.4
-
3
-
-
0026556331
-
Immunocytochemical localization of ubiquitin in inclusion body myositis allows its light-microscopic distinction from polymyositis
-
Askanas V, Serdaroglu P, Engel WK, Alvarez RB. 1992. Immunocytochemical localization of ubiquitin in inclusion body myositis allows its light-microscopic distinction from polymyositis. Neurology 42:460-461.
-
(1992)
Neurology
, vol.42
, pp. 460-461
-
-
Askanas, V.1
Serdaroglu, P.2
Engel, W.K.3
Alvarez, R.B.4
-
4
-
-
0036830228
-
The neuropathogenic contributione of lysosomal dysfunction
-
Bahr BA, Bendiske J. 2002. The neuropathogenic contributione of lysosomal dysfunction. J Neurochem 83:481-489.
-
(2002)
J Neurochem
, vol.83
, pp. 481-489
-
-
Bahr, B.A.1
Bendiske, J.2
-
5
-
-
1842563060
-
Substantia nigra Marinesco bodies are associated with decreased striatal expression of dopaminergic markers
-
Beach TG, Walker DG, Sue LI, Newell A, Adler CC, Joyce JN. 2004. Substantia nigra Marinesco bodies are associated with decreased striatal expression of dopaminergic markers. J Neuropathol Exp Neurol 63:329-337.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 329-337
-
-
Beach, T.G.1
Walker, D.G.2
Sue, L.I.3
Newell, A.4
Adler, C.C.5
Joyce, J.N.6
-
6
-
-
0030043663
-
Prevalence of parkinsonian signs and associated mortality in a community population of older people
-
Bennett DA, Beckett LA, Murray AM, Shannon KM, Goetz CG, Pilgrim DM, Evans DA. 1996. Prevalence of parkinsonian signs and associated mortality in a community population of older people. N Engl J Med 334:71-76.
-
(1996)
N Engl J Med
, vol.334
, pp. 71-76
-
-
Bennett, D.A.1
Beckett, L.A.2
Murray, A.M.3
Shannon, K.M.4
Goetz, C.G.5
Pilgrim, D.M.6
Evans, D.A.7
-
7
-
-
0029807321
-
Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system
-
Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ. 1996. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. J Neurosci 16:8019-8026.
-
(1996)
J Neurosci
, vol.16
, pp. 8019-8026
-
-
Berhow, M.T.1
Hiroi, N.2
Kobierski, L.A.3
Hyman, S.E.4
Nestler, E.J.5
-
8
-
-
0015745743
-
Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations
-
Bernheimer H, Birkmayer W, Hornykiewicz O, Jellinger K, Seitelberger F. 1973. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J Neurol Sci 20:415-455.
-
(1973)
J Neurol Sci
, vol.20
, pp. 415-455
-
-
Bernheimer, H.1
Birkmayer, W.2
Hornykiewicz, O.3
Jellinger, K.4
Seitelberger, F.5
-
9
-
-
0035104181
-
Alpha-synuclein immunopositive Parkinson's disease-related inclusion bodies in lower brain stem nuclei
-
Braak E, Sandmann-Keil D, Rub U, Gai WP, de Vos RA, Steur EN, Arai K, Braak H. 2001. Alpha-synuclein immunopositive Parkinson's disease-related inclusion bodies in lower brain stem nuclei. Acta Neuropathol (Berl) 101:195-201.
-
(2001)
Acta Neuropathol (Berl)
, vol.101
, pp. 195-201
-
-
Braak, E.1
Sandmann-Keil, D.2
Rub, U.3
Gai, W.P.4
de Vos, R.A.5
Steur, E.N.6
Arai, K.7
Braak, H.8
-
10
-
-
0342657004
-
Parkinson's disease: Affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system
-
Braak H, Rub U, Sandmann-Keil D, Gai WP, de Vos RA, Jansen Steur EN, Arai K, Braak E. 2000. Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system. Acta Neuropathol (Berl) 99:489-495.
-
(2000)
Acta Neuropathol (Berl)
, vol.99
, pp. 489-495
-
-
Braak, H.1
Rub, U.2
Sandmann-Keil, D.3
Gai, W.P.4
de Vos, R.A.5
Jansen Steur, E.N.6
Arai, K.7
Braak, E.8
-
11
-
-
0036236006
-
The mitochondrial-lysosomal axis theory of aging: Accumulation of damaged mitochondria as a result of imperfect autophagocytosis
-
Brunk UT, Terman A. 2002a. The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur J Biochem 269:1996-2002.
-
(2002)
Eur J Biochem
, vol.269
, pp. 1996-2002
-
-
Brunk, U.T.1
Terman, A.2
-
12
-
-
0036710928
-
Lipofuscin: Mechanisms of age-related accumulation and influence on cell function
-
Brunk UT, Terman A. 2002b. Lipofuscin: mechanisms of age-related accumulation and influence on cell function. Free Radic Biol Med 33:611-619.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 611-619
-
-
Brunk, U.T.1
Terman, A.2
-
13
-
-
0001496694
-
A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-l,2,3,6- tetrahydropyridine
-
Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, Kopin IJ. 1983. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-l,2,3,6- tetrahydropyridine. Proc Natl Acad Sci U S A 80:4546-4550.
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 4546-4550
-
-
Burns, R.S.1
Chiueh, C.C.2
Markey, S.P.3
Ebert, M.H.4
Jacobowitz, D.M.5
Kopin, I.J.6
-
15
-
-
33845387875
-
-
Neurobiol Aging
-
Cass WA, Grondin R, Andersen AH, Zhang Z, Hardy PA, Hussey-Andersen LK, Rayens WS, Gerhardt GA, Gash DM. 2006. Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeye. Neurobiol Aging.
-
(2006)
Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeye
-
-
Cass, W.A.1
Grondin, R.2
Andersen, A.H.3
Zhang, Z.4
Hardy, P.A.5
Hussey-Andersen, L.K.6
Rayens, W.S.7
Gerhardt, G.A.8
Gash, D.M.9
-
16
-
-
0033776095
-
Age-related decreases in GTP-cyclohydrolase-I immunoreactive neurons in the monkey and human substantia nigra
-
Chen EY, Kallwitz E, Leff SE, Cochran EJ, Mufeon EJ, Kordower JH, Mandel RJ. 2000. Age-related decreases in GTP-cyclohydrolase-I immunoreactive neurons in the monkey and human substantia nigra. J Comp Neurol 426(4):534-48.
-
(2000)
J Comp Neurol
, vol.426
, Issue.4
, pp. 534-548
-
-
Chen, E.Y.1
Kallwitz, E.2
Leff, S.E.3
Cochran, E.J.4
Mufeon, E.J.5
Kordower, J.H.6
Mandel, R.J.7
-
17
-
-
0021893795
-
-
Chiueh CC, Burns RS, Markey SP, Jacobowitz DM, Kopin IJ. 1985. Primate model of parkinsonism: selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeys. Life Sci 36(3):213-8.
-
Chiueh CC, Burns RS, Markey SP, Jacobowitz DM, Kopin IJ. 1985. Primate model of parkinsonism: selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeys. Life Sci 36(3):213-8.
-
-
-
-
18
-
-
33751118534
-
Age-aesociated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
-
Chu Y, Kordower JH. 2007. Age-aesociated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease? Neurobiol Dis 25(1): 134-49.
-
(2007)
Neurobiol Dis
, vol.25
, Issue.1
, pp. 134-149
-
-
Chu, Y.1
Kordower, J.H.2
-
19
-
-
0033168820
-
Diminished viability, growth, and behavioral efficacy of fetal dopamine neuron grafts in aging rats with long-term dopamine depletion: An argument for neurotrophic supplementation
-
Collier TJ, Sortwell CE, Daley BF. 1999. Diminished viability, growth, and behavioral efficacy of fetal dopamine neuron grafts in aging rats with long-term dopamine depletion: an argument for neurotrophic supplementation. J Neurosci 19:5563-5573.
-
(1999)
J Neurosci
, vol.19
, pp. 5563-5573
-
-
Collier, T.J.1
Sortwell, C.E.2
Daley, B.F.3
-
20
-
-
33947211176
-
Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: Diminished compensatory mechanisms as a prelude to parkinsonism
-
Jan 22; [Epub ahead of print
-
Collier TJ, Lipton J, Daley BF, Palfi S, Chu Y, Sortwell CE, Bakay RA, Sladek JR, Jr., Kordower JH. 2007. Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: Diminished compensatory mechanisms as a prelude to parkinsonism. Neurobiol Dis. Jan 22; [Epub ahead of print].
-
(2007)
Neurobiol Dis
-
-
Collier, T.J.1
Lipton, J.2
Daley, B.F.3
Palfi, S.4
Chu, Y.5
Sortwell, C.E.6
Bakay, R.A.7
Sladek Jr., J.R.8
Kordower, J.H.9
-
21
-
-
0032816549
-
The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease
-
Damier P, Hirsch EC, Agid Y, Graybiel AM. 1999. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain 122:1437-1448.
-
(1999)
Brain
, vol.122
, pp. 1437-1448
-
-
Damier, P.1
Hirsch, E.C.2
Agid, Y.3
Graybiel, A.M.4
-
22
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson TM, Dawson VL. 2003. Molecular pathways of neurodegeneration in Parkinson's disease. Science 302:819-822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
23
-
-
0025278909
-
Ubiquitin immunoreactive structures in normal human brains. Distribution and developmental aspects
-
Dickson DW, Wertkin A, Kress Y, Ksiezak-Reding H, Yen SH. 1990. Ubiquitin immunoreactive structures in normal human brains. Distribution and developmental aspects. Lab Invest 63:87-99.
-
(1990)
Lab Invest
, vol.63
, pp. 87-99
-
-
Dickson, D.W.1
Wertkin, A.2
Kress, Y.3
Ksiezak-Reding, H.4
Yen, S.H.5
-
24
-
-
0023281124
-
Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum
-
Elsworth JD, Deutch AY, Redmond DE Jr, Sladek JR Jr, Roth RH. 1987. Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum. Life Sci 40:193-202.
-
(1987)
Life Sci
, vol.40
, pp. 193-202
-
-
Elsworth, J.D.1
Deutch, A.Y.2
Redmond Jr, D.E.3
Sladek Jr, J.R.4
Roth, R.H.5
-
25
-
-
0032538911
-
Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys
-
Emborg ME, Ma SY, Mufson EJ, Levey AI, Taylor MD, Brown WD, Holden JE, Kordower JH. 1998. Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys. J Comp Neurol 401:253-265.
-
(1998)
J Comp Neurol
, vol.401
, pp. 253-265
-
-
Emborg, M.E.1
Ma, S.Y.2
Mufson, E.J.3
Levey, A.I.4
Taylor, M.D.5
Brown, W.D.6
Holden, J.E.7
Kordower, J.H.8
-
26
-
-
0025954066
-
Ageing and Parkinson's disease: Substantia nigra regional selectivity
-
Fearnley JM, Lees AJ. 1991. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114:2283-2301.
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
27
-
-
0034807238
-
Preferential recruitment of ataxin-3 independent of expanded polyglutamine: An immunohistochemical study on Marinesco bodies
-
Fujigasaki H, Uchihara T, Takahashi J, Matsushita H, Nakamura A, Koyano S, Iwabuchi K, Hirai S, Mizusawa H. 2001. Preferential recruitment of ataxin-3 independent of expanded polyglutamine: an immunohistochemical study on Marinesco bodies. J Neurol Neurosurg Psychiatry 71:518-520.
-
(2001)
J Neurol Neurosurg Psychiatry
, vol.71
, pp. 518-520
-
-
Fujigasaki, H.1
Uchihara, T.2
Takahashi, J.3
Matsushita, H.4
Nakamura, A.5
Koyano, S.6
Iwabuchi, K.7
Hirai, S.8
Mizusawa, H.9
-
28
-
-
0036270056
-
Changes in somatodendritic but not terminal dopamine regulation in aged rhesus monkeys
-
Gerhardt GA, Cass WA, Yi A, Zhang Z, Gash DM. 2002. Changes in somatodendritic but not terminal dopamine regulation in aged rhesus monkeys. J Neurochem 80:168-177.
-
(2002)
J Neurochem
, vol.80
, pp. 168-177
-
-
Gerhardt, G.A.1
Cass, W.A.2
Yi, A.3
Zhang, Z.4
Gash, D.M.5
-
29
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM. 2002. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 34:521-533.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
30
-
-
0025763177
-
Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease
-
Gibb WR, Lees AJ. 1991. Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease. J Neurol Neuroeurg Psychiatry 54:388-396.
-
(1991)
J Neurol Neuroeurg Psychiatry
, vol.54
, pp. 388-396
-
-
Gibb, W.R.1
Lees, A.J.2
-
31
-
-
0019507655
-
Regional changes of monoamines in cerebral cortex and subcortical structures of aging rhesus monkeys
-
Goldman-Rakic PS, Brown RM. 1981. Regional changes of monoamines in cerebral cortex and subcortical structures of aging rhesus monkeys. Neuroscience 6:177-187.
-
(1981)
Neuroscience
, vol.6
, pp. 177-187
-
-
Goldman-Rakic, P.S.1
Brown, R.M.2
-
33
-
-
0033854926
-
Dopaminergic therapy improves upper limb motor performance in aged rhesus monkeys
-
Grondin R, Zhang Z, Gerhardt GA, Gash DM. 2000. Dopaminergic therapy improves upper limb motor performance in aged rhesus monkeys. Ann Neurol 48:250-253.
-
(2000)
Ann Neurol
, vol.48
, pp. 250-253
-
-
Grondin, R.1
Zhang, Z.2
Gerhardt, G.A.3
Gash, D.M.4
-
34
-
-
0032507983
-
Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases
-
Gu M, Owen AD, Toffa SE, Cooper JM, Dexter DT, Jenner P, Marsden CD, Schapira AH. 1998. Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases. J Neurol Sci 158:24-29.
-
(1998)
J Neurol Sci
, vol.158
, pp. 24-29
-
-
Gu, M.1
Owen, A.D.2
Toffa, S.E.3
Cooper, J.M.4
Dexter, D.T.5
Jenner, P.6
Marsden, C.D.7
Schapira, A.H.8
-
35
-
-
0023740982
-
The nucleator
-
Gundersen HJ. 1988. The nucleator. J Microsc 151:3-21.
-
(1988)
J Microsc
, vol.151
, pp. 3-21
-
-
Gundersen, H.J.1
-
36
-
-
0033045425
-
The efficiency of systematic sampling in stereology - reconsidered
-
Gundersen HJ, Jensen EB, Kieu K, Nielsen J. 1999. The efficiency of systematic sampling in stereology - reconsidered. J Microsc 193:199-211.
-
(1999)
J Microsc
, vol.193
, pp. 199-211
-
-
Gundersen, H.J.1
Jensen, E.B.2
Kieu, K.3
Nielsen, J.4
-
37
-
-
0037226939
-
The neuronal ceroid-lipofuscinoses
-
Haltia M. 2003. The neuronal ceroid-lipofuscinoses. J Neuropathol Exp Neurol 62:1-13.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 1-13
-
-
Haltia, M.1
-
38
-
-
0029933450
-
Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections
-
Hastings TG, Lewis DA, Zigmond MJ. 1996. Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections. Proc Natl Acad Sci U S A 93:1956-1961.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1956-1961
-
-
Hastings, T.G.1
Lewis, D.A.2
Zigmond, M.J.3
-
39
-
-
0017355832
-
Aging of the substantia nigra, with special reference to Marinesco body]
-
Hirai S, Morimatsu M, Muramatsu A, Eto F, Yoshikawa M. 1977. [Aging of the substantia nigra, with special reference to Marinesco body]. Nippon Ronen Igakkai Zasshi 14:6-13.
-
(1977)
Nippon Ronen Igakkai Zasshi
, vol.14
, pp. 6-13
-
-
Hirai, S.1
Morimatsu, M.2
Muramatsu, A.3
Eto, F.4
Yoshikawa, M.5
-
40
-
-
0024384735
-
Ageing and neurotoxins as causative factors in idiopathic Parkinson's disease - a critical analysis of the neurochemical evidence
-
Hornykiewicz O. 1989. Ageing and neurotoxins as causative factors in idiopathic Parkinson's disease - a critical analysis of the neurochemical evidence. Prog Neuropsychopharmacol Biol Psychiatry 13:319-328.
-
(1989)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.13
, pp. 319-328
-
-
Hornykiewicz, O.1
-
41
-
-
0023836270
-
Neurochemical pathology and the etiology of Parkinson's disease: Basic facts and hypothetical possibilities
-
Hornykiewicz O. 1988. Neurochemical pathology and the etiology of Parkinson's disease: basic facts and hypothetical possibilities. Mt Sinai J Med 55(1):11-20.
-
(1988)
Mt Sinai J Med
, vol.55
, Issue.1
, pp. 11-20
-
-
Hornykiewicz, O.1
-
42
-
-
0035032930
-
Aging and caloric restriction in nonhuman primates: Behavioral and in vivo brain imaging studies
-
Ingram DK, Chefer S, Matochik J, Moscrip TD, Weed J, Roth GS, London ED, Lane MA. 2001. Aging and caloric restriction in nonhuman primates: behavioral and in vivo brain imaging studies. Ann N Y Acad Sci 928:316-326.
-
(2001)
Ann N Y Acad Sci
, vol.928
, pp. 316-326
-
-
Ingram, D.K.1
Chefer, S.2
Matochik, J.3
Moscrip, T.D.4
Weed, J.5
Roth, G.S.6
London, E.D.7
Lane, M.A.8
-
43
-
-
0028695965
-
Aging and the nigrostriatal dopamine system: A non-human primate study
-
Irwin I, DeLanney LE, McNeill T, Chan P, Forno LS, Murphy GM, Jr., Di Monte DA, Sandy MS, Langston JW. 1994. Aging and the nigrostriatal dopamine system: a non-human primate study. Neurodegeneration 3:251-265.
-
(1994)
Neurodegeneration
, vol.3
, pp. 251-265
-
-
Irwin, I.1
DeLanney, L.E.2
McNeill, T.3
Chan, P.4
Forno, L.S.5
Murphy Jr., G.M.6
Di Monte, D.A.7
Sandy, M.S.8
Langston, J.W.9
-
44
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
Jenner P. 2003. Oxidative stress in Parkinson's disease. Ann Neurol 53(Suppl 3):S26-S36.
-
(2003)
Ann Neurol
, vol.53
, Issue.SUPPL. 3
-
-
Jenner, P.1
-
45
-
-
0034008608
-
The connections of the dopaminergic system with the striatum in rats and primates: An analysis with respect to the functional and compartmental organization of the striatum
-
Joel D, Weiner I. 2000. The connections of the dopaminergic system with the striatum in rats and primates: an analysis with respect to the functional and compartmental organization of the striatum. Neuroscience 96:451-474.
-
(2000)
Neuroscience
, vol.96
, pp. 451-474
-
-
Joel, D.1
Weiner, I.2
-
46
-
-
0024336199
-
Ceroid-lipofuscinosis (Batten's disease): Pathogenesis and sequential neuropathological changes in the ovine model
-
Jolly RD, Shimada A, Dopfmer I, Slack PM, Birtles MJ, Palmer DN. 1989. Ceroid-lipofuscinosis (Batten's disease): pathogenesis and sequential neuropathological changes in the ovine model. Neuropathol Appl Neurobiol 15:371-383.
-
(1989)
Neuropathol Appl Neurobiol
, vol.15
, pp. 371-383
-
-
Jolly, R.D.1
Shimada, A.2
Dopfmer, I.3
Slack, P.M.4
Birtles, M.J.5
Palmer, D.N.6
-
47
-
-
4344618623
-
Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain
-
Keller JN, Dimayuga E, Chen Q, Thorpe J, Gee J, Ding Q. 2004. Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain. Int J Biochem Cell Biol 36:2376-2391.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2376-2391
-
-
Keller, J.N.1
Dimayuga, E.2
Chen, Q.3
Thorpe, J.4
Gee, J.5
Ding, Q.6
-
48
-
-
0036318682
-
Intranuclear aggregation of nonexpanded ataxin-3 in Marinesco bodies of the nonhuman primate substantia nigra
-
Kettner M, Willwohl D, Hubbard GB, Rub U, Dick EJ Jr, Cox AB, Trottier Y, Auburger G, Braak H, Schultz C. 2002. Intranuclear aggregation of nonexpanded ataxin-3 in Marinesco bodies of the nonhuman primate substantia nigra. Exp Neurol 176:117-121.
-
(2002)
Exp Neurol
, vol.176
, pp. 117-121
-
-
Kettner, M.1
Willwohl, D.2
Hubbard, G.B.3
Rub, U.4
Dick Jr, E.J.5
Cox, A.B.6
Trottier, Y.7
Auburger, G.8
Braak, H.9
Schultz, C.10
-
49
-
-
0023874410
-
Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
-
Kish SJ, Shannak K, Hornykiewicz O. 1988. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N Engl J Med 318:876-880.
-
(1988)
N Engl J Med
, vol.318
, pp. 876-880
-
-
Kish, S.J.1
Shannak, K.2
Hornykiewicz, O.3
-
50
-
-
0026569594
-
Aging produces a specific pattern of striatal dopamine loss: Implications for the etiology of idiopathic Parkinson's disease
-
Kish SJ, Shannak K, Rajput A, Deck JH, Hornykiewicz O. 1992. Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease. J Neurochem 58:642-648.
-
(1992)
J Neurochem
, vol.58
, pp. 642-648
-
-
Kish, S.J.1
Shannak, K.2
Rajput, A.3
Deck, J.H.4
Hornykiewicz, O.5
-
51
-
-
0022495047
-
Injury of nigral neurons exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A tyrosine hydroxylase immunocytochemical study in monkey
-
Kitt CA, Cork LC, Eidelberg F, Joh TH, Price DL. 1986. Injury of nigral neurons exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a tyrosine hydroxylase immunocytochemical study in monkey. Neuroscience 17:1089-10103.
-
(1986)
Neuroscience
, vol.17
, pp. 1089-10103
-
-
Kitt, C.A.1
Cork, L.C.2
Eidelberg, F.3
Joh, T.H.4
Price, D.L.5
-
52
-
-
0027941082
-
Glutamate uptake blockade induces striatal dopamine release in 6-hydroxydopamine rats with intrastriatal grafts: Evidence for host modulation of transplanted dopamine neurons
-
Kondoh T, Low WC. 1994. Glutamate uptake blockade induces striatal dopamine release in 6-hydroxydopamine rats with intrastriatal grafts: evidence for host modulation of transplanted dopamine neurons. Exp Neurol 127:191-198.
-
(1994)
Exp Neurol
, vol.127
, pp. 191-198
-
-
Kondoh, T.1
Low, W.C.2
-
53
-
-
0036840222
-
Promyelocytic leukemia protein is redistributed during the formation of intranuclear inclusions independent of polyglutamine expansion: An immunohistochemical study on Marinesco bodies
-
Kumada S, Uchihara T, Hayashi M, Nakamura A, Kikuchi E, Mizutani T, Oda M. 2002. Promyelocytic leukemia protein is redistributed during the formation of intranuclear inclusions independent of polyglutamine expansion: an immunohistochemical study on Marinesco bodies. J Neuropathol Exp Neurol 61:984-991.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 984-991
-
-
Kumada, S.1
Uchihara, T.2
Hayashi, M.3
Nakamura, A.4
Kikuchi, E.5
Mizutani, T.6
Oda, M.7
-
54
-
-
0031715849
-
Epidemiology versus genetics in Parkinson's disease: Progress in resolving an age-old debate
-
Langston JW. 1998. Epidemiology versus genetics in Parkinson's disease: progress in resolving an age-old debate. Ann Neurol 44(3 Suppl 1):S45-S52.
-
(1998)
Ann Neurol
, vol.44
, Issue.3 SUPPL. 1
-
-
Langston, J.W.1
-
56
-
-
0028274024
-
The organization of midbrain projections to the striatum in the primate: Sensorimotor-related striatum versus ventral striatum
-
Lynd-Balta E, Haber SN. 1994a. The organization of midbrain projections to the striatum in the primate: sensorimotor-related striatum versus ventral striatum. Neuroscience 59:625-640.
-
(1994)
Neuroscience
, vol.59
, pp. 625-640
-
-
Lynd-Balta, E.1
Haber, S.N.2
-
57
-
-
0028273168
-
The organization of midbrain projections to the ventral striatum in the primate
-
Lynd-Balta E, Haber SN. 1994b. The organization of midbrain projections to the ventral striatum in the primate. Neuroscience 59:609-623.
-
(1994)
Neuroscience
, vol.59
, pp. 609-623
-
-
Lynd-Balta, E.1
Haber, S.N.2
-
58
-
-
0034105979
-
The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK
-
MacDonald BK, Cockerell OC, Sander JW, Shorvon SD. 2000. The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK. Brain 123:665-676.
-
(2000)
Brain
, vol.123
, pp. 665-676
-
-
MacDonald, B.K.1
Cockerell, O.C.2
Sander, J.W.3
Shorvon, S.D.4
-
59
-
-
1642523445
-
Aging of the nigrostriatal system in the squirrel monkey
-
McCormack AL, Di Monte DA, Delfani K, Irwin I, DeLanney LE, Langston WJ, Janson AM. 2004. Aging of the nigrostriatal system in the squirrel monkey. J Comp Neurol 471:387-395.
-
(2004)
J Comp Neurol
, vol.471
, pp. 387-395
-
-
McCormack, A.L.1
Di Monte, D.A.2
Delfani, K.3
Irwin, I.4
DeLanney, L.E.5
Langston, W.J.6
Janson, A.M.7
-
60
-
-
33344461775
-
Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease
-
McNaught KS, Olanow CW. 2006. Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease. Neurobiol Aging 27:530-545.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 530-545
-
-
McNaught, K.S.1
Olanow, C.W.2
-
61
-
-
0037159608
-
Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease
-
Meredith GE, Totterdell S, Petroske E, Santa CK, Callison RC Jr, Lau YS. 2002. Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease. Brain Res 956:156-165.
-
(2002)
Brain Res
, vol.956
, pp. 156-165
-
-
Meredith, G.E.1
Totterdell, S.2
Petroske, E.3
Santa, C.K.4
Callison Jr, R.C.5
Lau, Y.S.6
-
62
-
-
0027351361
-
Mitochondrial energy crisis in Parkinson's disease
-
Mizuno Y, Ikebe S, Hattori N, Kondo T, Tanaka M, Ozawa T. 1993. Mitochondrial energy crisis in Parkinson's disease. Adv Neurol 60:282-287.
-
(1993)
Adv Neurol
, vol.60
, pp. 282-287
-
-
Mizuno, Y.1
Ikebe, S.2
Hattori, N.3
Kondo, T.4
Tanaka, M.5
Ozawa, T.6
-
63
-
-
0037986563
-
Vacuole-creating protein in neurodegenerative diseases in humans
-
Mizuno Y, Hori S, Kakizuka A, Okamoto K. 2003. Vacuole-creating protein in neurodegenerative diseases in humans. Neurosci Lett 343:77-80.
-
(2003)
Neurosci Lett
, vol.343
, pp. 77-80
-
-
Mizuno, Y.1
Hori, S.2
Kakizuka, A.3
Okamoto, K.4
-
64
-
-
0029935219
-
Epidemiologic observations on Parkinson's disease: Incidence and mortality in a prospective study of middle-aged men
-
Morens DM, Davis JW, Grandinetti A, Ross GW, Popper JS, White LR. 1996. Epidemiologic observations on Parkinson's disease: incidence and mortality in a prospective study of middle-aged men. Neurology 46:1044-1050.
-
(1996)
Neurology
, vol.46
, pp. 1044-1050
-
-
Morens, D.M.1
Davis, J.W.2
Grandinetti, A.3
Ross, G.W.4
Popper, J.S.5
White, L.R.6
-
65
-
-
0027938964
-
Brain aging: A risk factor of neurodegenerative disorders and a target for therapeutic intervention
-
Muller WE, Pedigo NW Jr. 1994. Brain aging: a risk factor of neurodegenerative disorders and a target for therapeutic intervention. Life Sci 55:1975-1976.
-
(1994)
Life Sci
, vol.55
, pp. 1975-1976
-
-
Muller, W.E.1
Pedigo Jr., N.W.2
-
66
-
-
24044496235
-
Glial activation spreads from specific cerebral foci and precedes neurodegeneration in presymptomatic ovine neuronal ceroid lipofuscinosis (CLN6)
-
Oswald MJ, Palmer DN, Kay GW, Shemilt SJ, Rezaie P, Cooper JD. 2005. Glial activation spreads from specific cerebral foci and precedes neurodegeneration in presymptomatic ovine neuronal ceroid lipofuscinosis (CLN6). Neurobiol Dis 20:49-63.
-
(2005)
Neurobiol Dis
, vol.20
, pp. 49-63
-
-
Oswald, M.J.1
Palmer, D.N.2
Kay, G.W.3
Shemilt, S.J.4
Rezaie, P.5
Cooper, J.D.6
-
67
-
-
0029080869
-
A stereological study of substantia nigra in young and old rhesus monkeys
-
Pakkenberg H, Andersen BB, Burns RS, Pakkenberg B. 1995. A stereological study of substantia nigra in young and old rhesus monkeys. Brain Res 693:201-206.
-
(1995)
Brain Res
, vol.693
, pp. 201-206
-
-
Pakkenberg, H.1
Andersen, B.B.2
Burns, R.S.3
Pakkenberg, B.4
-
68
-
-
0036119907
-
The origin of fluorescence in the neuronal ceroid lipofuscinoses (Batten disease) and neuron cultures from affected sheep for studies of neurodegeneration
-
Palmer DN, Oswald MJ, Westlake VJ, Kay GW. 2002. The origin of fluorescence in the neuronal ceroid lipofuscinoses (Batten disease) and neuron cultures from affected sheep for studies of neurodegeneration. Arch Gerontol Geriatr 34:343-357.
-
(2002)
Arch Gerontol Geriatr
, vol.34
, pp. 343-357
-
-
Palmer, D.N.1
Oswald, M.J.2
Westlake, V.J.3
Kay, G.W.4
-
69
-
-
33745410626
-
Mitochondrial disease
-
Schapira AH. 2006. Mitochondrial disease. Lancet 368:70-82.
-
(2006)
Lancet
, vol.368
, pp. 70-82
-
-
Schapira, A.H.1
-
70
-
-
0023187166
-
Selective loss of subpopulations of ventral mesencephalic dopaminergic neurons in the monkey following exposure to MPTP
-
Schneider JS, Yuwiler A, Markham CH. 1987. Selective loss of subpopulations of ventral mesencephalic dopaminergic neurons in the monkey following exposure to MPTP. Brain Res 411:144-150.
-
(1987)
Brain Res
, vol.411
, pp. 144-150
-
-
Schneider, J.S.1
Yuwiler, A.2
Markham, C.H.3
-
71
-
-
0032874037
-
The effect of aging on pars compacta of the substantia nigra in rhesus monkey
-
Siddiqi ZA, Peters A. 1999. The effect of aging on pars compacta of the substantia nigra in rhesus monkey. J Neuropathol Exp Neurol 58:903-920.
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 903-920
-
-
Siddiqi, Z.A.1
Peters, A.2
-
72
-
-
0032862994
-
Age-related neuronal loss from the substantia nigra-pars compacta and ventral tegmental area of the rhesus monkey
-
Siddiqi Z, Kemper TL, Killiany R. 1999. Age-related neuronal loss from the substantia nigra-pars compacta and ventral tegmental area of the rhesus monkey. J Neuropathol Exp Neurol 58:959-971.
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 959-971
-
-
Siddiqi, Z.1
Kemper, T.L.2
Killiany, R.3
-
73
-
-
0032568534
-
Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
-
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. 1998. Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci U S A 95:6469-6473.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
74
-
-
5444238860
-
Histological changes of the dopaminergic nigrostriatal system in aging
-
Stark AK, Pakkenberg B. 2004. Histological changes of the dopaminergic nigrostriatal system in aging. Cell Tissue Res 318:81-92.
-
(2004)
Cell Tissue Res
, vol.318
, pp. 81-92
-
-
Stark, A.K.1
Pakkenberg, B.2
-
75
-
-
0035894855
-
Expression of A53T mutant but not wild-type alpha-synuclein in PC 12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
-
Stefanis L, Larsen KE, Rideout HJ, Sulzer D, Greene LA. 2001. Expression of A53T mutant but not wild-type alpha-synuclein in PC 12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci 21:9549-9560.
-
(2001)
J Neurosci
, vol.21
, pp. 9549-9560
-
-
Stefanis, L.1
Larsen, K.E.2
Rideout, H.J.3
Sulzer, D.4
Greene, L.A.5
-
76
-
-
0029937494
-
Epidemiology of Parkinson's disease
-
Tanner CM, Goldman SM. 1996. Epidemiology of Parkinson's disease. Neurol Clin 14:317-335.
-
(1996)
Neurol Clin
, vol.14
, pp. 317-335
-
-
Tanner, C.M.1
Goldman, S.M.2
-
79
-
-
20444494338
-
Prevalence of Parkinson's disease in the L'Aquila district, central Italy
-
Totaro R, Marini C, Pistoia F, Sacco S, Russo T, Carolei A. 2005. Prevalence of Parkinson's disease in the L'Aquila district, central Italy. Acta Neurol Scand 112:24-28.
-
(2005)
Acta Neurol Scand
, vol.112
, pp. 24-28
-
-
Totaro, R.1
Marini, C.2
Pistoia, F.3
Sacco, S.4
Russo, T.5
Carolei, A.6
-
80
-
-
0025069974
-
Tetrahydrobiopterin-dependent production of L-dopa in NRK fibroblasts transfected with tyrosine hydroxylase cDNA: Future use for intracerebral grafting
-
Uchida K, Ishii A, Kaneda N, Toya S, Nagatsu T, Kohsaka S. 1990. Tetrahydrobiopterin-dependent production of L-dopa in NRK fibroblasts transfected with tyrosine hydroxylase cDNA: future use for intracerebral grafting. Neurosci Lett 109:282-286.
-
(1990)
Neurosci Lett
, vol.109
, pp. 282-286
-
-
Uchida, K.1
Ishii, A.2
Kaneda, N.3
Toya, S.4
Nagatsu, T.5
Kohsaka, S.6
-
81
-
-
0024399969
-
Altered lipofuscin pigmentation in the basal nucleus (Meynert) in Parkinson's disease
-
Ulfig N. 1989. Altered lipofuscin pigmentation in the basal nucleus (Meynert) in Parkinson's disease. Neurosci Res 6:456-462.
-
(1989)
Neurosci Res
, vol.6
, pp. 456-462
-
-
Ulfig, N.1
-
82
-
-
0025327731
-
Unbiased stereological estimation of the number of neurons in the human hippocampus
-
West MJ, Gundersen HJ. 1990. Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 296:1-22.
-
(1990)
J Comp Neurol
, vol.296
, pp. 1-22
-
-
West, M.J.1
Gundersen, H.J.2
-
83
-
-
0000680812
-
The morphology of Marinesco bodies (paranucleolar corpuscles) in the melanin-pigmented nuclei of the brain-stem
-
Yuen P, Baxter DW. 1963. The morphology of Marinesco bodies (paranucleolar corpuscles) in the melanin-pigmented nuclei of the brain-stem. J Neurol Neurosurg Psychiatry 26:178-183.
-
(1963)
J Neurol Neurosurg Psychiatry
, vol.26
, pp. 178-183
-
-
Yuen, P.1
Baxter, D.W.2
-
84
-
-
0034544939
-
Motor slowing and parkinsonian signs in aging rhesus monkeys mirror human aging
-
Zhang Z, Andersen A, Smith C, Grondin R, Gerhardt G, Gash D. 2000. Motor slowing and parkinsonian signs in aging rhesus monkeys mirror human aging. J Gerontol A Biol Sci Med Sci 55:B473-B480.
-
(2000)
J Gerontol A Biol Sci Med Sci
, vol.55
-
-
Zhang, Z.1
Andersen, A.2
Smith, C.3
Grondin, R.4
Gerhardt, G.5
Gash, D.6
|