The effect of vagal cooling on canine hepatic glucose metabolism in the presence of hyperglycemia of peripheral origin

Metabolism: Clinical and Experimental

Volumn 56, Issue 6, 2007, Pages 814-824

  DiCostanzo, Catherine A ^a   Dardevet, Dominique P ^a   Williams, Phil E ^a   Courtney Moore, Mary ^a   Hastings, Jon R ^a   Neal, Doss W ^a   Cherrington, Alan D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; GLUCOSE; INSULIN; SOMATOSTATIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COOLING; DOG; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HEART RATE; HYPERGLYCEMIA; NONHUMAN; PERIPHERAL VEIN; PRIORITY JOURNAL; VAGUS NERVE;

ANIMALS; BLOOD GLUCOSE; COLD; DOGS; GLUCOSE; HYPERGLYCEMIA; LACTIC ACID; LIVER; LIVER CIRCULATION; VAGUS NERVE;

EID: 34248383204     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2007.01.012     Document Type: Article

References (63)

1. Myers S.R., McGuinness O.P., Neal D.W., and Cherrington A.D. Intraportal glucose delivery alters the relationship between net hepatic glucose uptake and the insulin concentration. J Clin Invest 88 (1991) 158-167
2. Holste L.C., Connolly C.C., Moore M.C., Neal D.W., and Cherrington A.D. Physiological changes in circulating glucagon alter hepatic glucose disposition during portal glucose delivery. Am J Physiol 273 (1997) E488-E496
3. Adkins B.A., Myers S.R., Hendrick G.K., Stevenson R.W., Williams P.E., and Cherrington A.D. Importance of the route of intravenous glucose delivery to hepatic glucose balance in the conscious dog. J Clin Invest 79 (1987) 557-565
4. Pagliassotti M.J., Holste L.C., Moore M.C., Neal D.W., and Cherrington A.D. Comparison of the time courses of insulin and the portal signal on hepatic glucose and glycogen metabolism in the conscious dog. J Clin Invest 97 (1996) 81-91
5. Hsieh P.S., Moore M.C., Neal D.W., and Cherrington A.D. Hepatic glucose uptake rapidly decreases after removal of the portal signal in conscious dogs. Am J Physiol 275 (1998) E987-E992
6. Shimazu T., and Fukuda A. Increased activities of glycogenolytic enzymes in liver after splanchnic-nerve stimulation. Science 150 (1965) 1607-1608
7. Shimazu T., Fukuda A., and Ban T. Reciprocal influences of the ventromedial and lateral hypothalamic nuclei on blood glucose level and liver glycogen content. Nature 210 (1966) 1178-1179
8. Tiniakos D.G., Lee J.A., and Burt A.D. Innervation of the liver: morphology and function. Liver 16 (1996) 151-160
9. Shimazu T. Central nervous system regulation of liver and adipose tissue metabolism. Diabetologia 20 (1981) 343-356
10. Shimazu T. Reciprocal innervation of the liver: its significance in metabolic control. Adv Metab Disord 10 (1983) 355-384
11. Shimazu T. Neuronal regulation of hepatic glucose metabolism in mammals. Diabetes Metab Rev 3 (1987) 185-206
12. Shimazu T., and Amakawa A. Regulation of glycogen metabolism in liver by the autonomic nervous system. Vi. Possible mechanism of phosphorylase activation by the splanchnic nerve. Biochim Biophys Acta 385 (1975) 242-256
13. Stumpel F., and Jungermann K. Sensing by intrahepatic muscarinic nerves of a portal-arterial glucose concentration gradient as a signal for insulin-dependent glucose uptake in the perfused rat liver. FEBS Lett 406 (1997) 119-122
14. Sakaguchi T., and Iwanaga M. Effects of d-glucose anomers on afferent discharge in the hepatic vagus nerve. Experientia 38 (1982) 475-476
15. Uyama N., Geerts A., and Reynaert H. Neural connections between the hypothalamus and the liver. Anat Rec A Discov Mol Cell Evol Biol 280A (2004) 808-820
16. Niijima A. Glucose-sensitive afferent nerve fibres in the hepatic branch of the vagus nerve in the guinea-pig. J Physiol 332 (1982) 315-323
17. Nagase H., Inoue S., Tanaka K., Takamura Y., and Niijima A. Hepatic glucose-sensitive unit regulation of glucose-induced insulin secretion in rats. Physiol Behav 53 (1993) 139-143
18. Hevener A.L., Bergman R.N., and Donovan C.M. Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes 49 (2000) 8-12
19. Jackson P.A., Pagliassotti M.J., Shiota M., Neal D.W., Cardin S., and Cherrington A.D. Effects of vagal blockade on the counterregulatory response to insulin-induced hypoglycemia in the dog. Am J Physiol 273 (1997) E1178-E1188
20. Jackson P.A., Cardin S., Coffey C.S., Neal D.W., Allen E.J., Penaloza A.R., et al. Effect of hepatic denervation on the counterregulatory response to insulin-induced hypoglycemia in the dog. Am J Physiol Endocrinol Metab 279 (2000) E1249-E1257
21. Lamarche L., Yamaguchi N., and Peronnet F. Hepatic denervation reduces adrenal catecholamine secretion during insulin-induced hypoglycemia. Am J Physiol 268 (1995) R50-R57
22. Perseghin G., Regalia E., Battezzati A., Vergani S., Pulvirenti A., Terruzzi I., et al. Regulation of glucose homeostasis in humans with denervated livers. J Clin Invest 100 (1997) 931-941
23. Matsuhisa M., Yamasaki Y., Shiba Y., Nakahara I., Kuroda A., Tomita T., et al. Important role of the hepatic vagus nerve in glucose uptake and production by the liver. Metabolism 49 (2000) 11-16
24. Cardin S., Walmsley K., Neal D.W., Williams P.E., and Cherrington A.D. Involvement of the vagus nerves in the regulation of basal hepatic glucose production in conscious dogs. Am J Physiol Endocrinol Metab 283 (2002) E958-E964
25. Adkins-Marshall B.A., Neal D.W., Pugh W., Jaspan J.B., Cherrington A.D., and Adkins-Marshall B. Role of hepatic nerves in response of liver to intraportal glucose delivery in dogs. Diabetes 41 (1992) 1308-1319
26. Russek M. Current status of the hepatostatic theory of food intake control. Appetite 2 (1981) 137-143
27. Ikeda T., Scott M., Emshwiller M.G., Monohan M.T., Allen E., Sindelar D.K., et al. Hyperglycemia reduces sympathetic nervous signaling to the liver and gut in the dog. Diabetes 46 (1997) 232A
28. Mundinger T.O., Boyle M.R., and Taborsky Jr. G.J. Activation of hepatic sympathetic nerves during hypoxic, hypotensive and glucopenic stress. J Auton Nerv Syst 63 (1997) 153-160
29. DiCostanzo C.A., Dardevet D.P., Neal D.W., Lautz M., Allen E., Snead W., et al. Role of the hepatic sympathetic nerves in the regulation of net hepatic glucose uptake and the mediation of the portal glucose signal. Am J Physiol Endocrinol Metab 290 (2006) E9-E16
30. Lautt W.W., and Wong C. Hepatic parasympathetic neural effect on glucose balance in the intact liver. Can J Physiol Pharmacol 56 (1978) 679-682
31. Shimazu T. Regulation of glycogen metabolism in liver by the autonomic nervous system. V. Activation of glycogen synthetase by vagal stimulation. Biochim Biophys Acta 252 (1971) 28-38
32. Mondon C.E., and Burton S.D. Factors modifying carbohydrate metabolism and effect of insulin in perfused rat liver. Am J Physiol 220 (1971) 724-734
33. Shiota M., Jackson P., Galassetti P., Scott M., Neal D.W., and Cherrington A.D. Combined intraportal infusion of acetylcholine and adrenergic blockers augments net hepatic glucose uptake. Am J Physiol Endocrinol Metab 278 (2000) E544-E552
34. Cardin S., Pagliassotti M.J., Moore M.C., Edgerton D.S., Lautz M., Farmer B., et al. Vagal cooling and concomitant portal norepinephrine infusion do not reduce net hepatic glucose uptake in conscious dogs. Am J Physiol Regul Integr Comp Physiol 287 (2004) R742-R748
35. Myers S.R., Hendrick G.K., Williams P.E., Triebwasser K., Floyd B., Cherrington A.D., et al. Importance of the route of intravenous glucose delivery to hepatic glucose balance in the conscious dog. Diabetes 39 (1990) 87-95
36. Leon D.F., Shaver J.A., and Leonard J.J. Reflex heart rate control in man. Am Heart J 80 (1970) 729-739
37. Scher A.M., and Young A.C. Reflex control of heart rate in the unanesthetized dog. Am J Physiol 218 (1970) 780-789
38. Chung S.A., Valdez D.T., and Diamant N.E. Adrenergic blockage does not restore the canine gastric migrating motor complex during vagal blockade. Gastroenterology 103 (1992) 1491-1497
39. Galassetti P., Chu C.A., Neal D.W., Reed G.W., Wasserman D.H., and Cherrington A.D. A negative arterial-portal venous glucose gradient increases net hepatic glucose uptake in euglycemic dogs. Am J Physiol 277 (1999) E126-E134
40. Leevy C.M., Mendenhall C.L., Lesko W., and Howard M.M. Estimation of hepatic blood flow with indocyanine green. J Clin Invest 41 (1962) 1169-1179
41. Dardevet D., Moore M.C., DiCostanzo C.A., Farmer B., Neal D.W., Snead W., et al. Insulin secretion-independent effects of glp-1 on canine liver glucose metabolism do not involve portal vein glp-1 receptors. Am J Physiol Gastrointest Liver Physiol 289 (2005) G806-G814
42. Hsieh P.S., Moore M.C., Neal D.W., Emshwiller M., and Cherrington A.D. Rapid reversal of the effects of the portal signal under hyperinsulinemic conditions in the conscious dog. Am J Physiol 276 (1999) E930-E937
43. DiCostanzo C.A., Moore M.C., Lautz M., Scott M., Farmer B., Everett C.A., et al. Simulated first-phase insulin release using humulin or an insulin analogue (him2) is associated with prolonged improvement in post-prandial glycemia. Am J Physiol Endocrinol Metab 15 (2005) 15
44. Niijima A. Glucose-sensitive afferent nerve fibers in the liver and their role in food intake and blood glucose regulation. J Auton Nerv Syst 9 (1983) 207-220
45. Niijima A. Electrophysiological study on nervous pathway from splanchnic nerve to vagus nerve in rat. Am J Physiol 244 (1983) R888-R890
46. Niijima A. Nervous regulation of metabolism. Prog Neurobiol 33 (1989) 135-147
47. Niijima A., Fukuda A., Taguchi T., and Okuda J. Suppression of afferent activity of the hepatic vagus nerve by anomers of d-glucose. Am J Physiol 244 (1983) R611-R614
48. Niijima A. Reflex control of the autonomic nervous system activity from the glucose sensors in the liver in normal and midpontine-transected animals. J Auton Nerv Syst 10 (1984) 279-285
49. Alexander W.F. The innervation of the biliary system. J Comp Neurol 72 (1940) 357-370
50. Reilly F.D., McCuskey P.A., and McCuskey R.S. Intrahepatic distribution of nerves in the rat. Anat Rec 191 (1978) 55-67
51. Bioulac-Sage P., Lafon M.E., Saric J., and Balabaud C. Nerves and perisinusoidal cells in human liver. J Hepatol 10 (1990) 105-112
52. Nonogaki K. New insights into sympathetic regulation of glucose and fat metabolism. Diabetologia 43 (2000) 533-549
53. Franz D.N., and Iggo A. Conduction failure in myelinated and non-myelinated axons at low temperatures. J Physiol 199 (1968) 319-345
54. Hsieh P.S., Moore M.C., Neal D.W., and Cherrington A.D. Importance of the hepatic arterial glucose level in generation of the portal signal in conscious dogs. Am J Physiol Endocrinol Metab 279 (2000) E284-E292
55. Berthoud H.R. Anatomy and function of sensory hepatic nerves. Anat Rec A Discov Mol Cell Evol Biol 280 (2004) 827-835
56. Fujita S., and Donovan C.M. Celiac-superior mesenteric ganglionectomy, but not vagotomy, suppresses the sympathoadrenal response to insulin-induced hypoglycemia. Diabetes 54 (2005) 3258-3264
57. Novin D., VanderWeele D.A., and Rezek M. Infusion of 2-deoxy-d-glucose into the hepatic-portal system causes eating: evidence for peripheral glucoreceptors. Science 181 (1973) 858-860
58. Bobbioni E., Marre M., Helman A., and Assan R. The nervous control of rat glucagon secretion in vivo. Horm Metab Res 15 (1983) 133-138
59. Gardemann A., and Jungermann K. Control of glucose balance in the perfused rat liver by the parasympathetic innervation. Biol Chem Hoppe Seyler 367 (1986) 559-566
60. Koo A., and Liang I.Y. Microvascular filling pattern in rat liver sinusoids during vagal stimulation. J Physiol 295 (1979) 191-199
61. Kurosawa M., Unno T., Aikawa Y., and Yoneda M. Neural regulation of hepatic blood flow in rats: an in vivo study. Neurosci Lett 321 (2002) 145-148
62. Tamori K., Yoneda M., Nakamura K., and Makino I. Effect of intracisternal thyrotropin-releasing hormone on hepatic blood flow in rats. Am J Physiol 274 (1998) G277-G282
63. Cardin S., Jackson P.A., Edgerton D.S., Neal D.W., Coffey C.S., and Cherrington A.D. Effect of vagal cooling on the counterregulatory response to hypoglycemia induced by a low dose of insulin in the conscious dog. Diabetes 50 (2001) 558-564