-
1
-
-
0033554684
-
Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid, Children's Cancer Group
-
Matthay KK, Villablanca JG, Seeger RC, Stram DO, Harris RE, Ramsay NK, Swift P, Shimada H, Black CT, Brodeur GM, Gerbing RB, Reynolds CP. Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid, Children's Cancer Group. NEJM 1999;341:1165-1173.
-
(1999)
NEJM
, vol.341
, pp. 1165-1173
-
-
Matthay, K.K.1
Villablanca, J.G.2
Seeger, R.C.3
Stram, D.O.4
Harris, R.E.5
Ramsay, N.K.6
Swift, P.7
Shimada, H.8
Black, C.T.9
Brodeur, G.M.10
Gerbing, R.B.11
Reynolds, C.P.12
-
2
-
-
0037457348
-
Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN
-
Misawa A, Hosoi H, Tsuchiya K, Sugimoto T. Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN. Int J Cancer 2003;104:233-237.
-
(2003)
Int J Cancer
, vol.104
, pp. 233-237
-
-
Misawa, A.1
Hosoi, H.2
Tsuchiya, K.3
Sugimoto, T.4
-
3
-
-
30344442477
-
Differential sensitivity of chemoresistant neuroblastoma subtypes to MAPK-targeted treatment correlates with ERK, p53 expression, and signaling response to U0126
-
Eppstein AC, Sandoval JA, Klein PJ, Woodruff HA, Grosfeld JL, Hickey RJ, Malkas LH, Schmidt CM. Differential sensitivity of chemoresistant neuroblastoma subtypes to MAPK-targeted treatment correlates with ERK, p53 expression, and signaling response to U0126. J Pediatr Surg 2006;41:252-259.
-
(2006)
J Pediatr Surg
, vol.41
, pp. 252-259
-
-
Eppstein, A.C.1
Sandoval, J.A.2
Klein, P.J.3
Woodruff, H.A.4
Grosfeld, J.L.5
Hickey, R.J.6
Malkas, L.H.7
Schmidt, C.M.8
-
4
-
-
33747443493
-
Effect of bortezomib on human neuroblastoma cell growth, apoptosis and angiogenesis
-
Brignole C, Marimpietri D, Pastorino F, Nico B, Di Paolo D, Cioni M, Piccardi F, Cilli M, Pezzolo A, Corrias MV, Pistoia V, Ribatti D, Pagnan G, Ponzoni M. Effect of bortezomib on human neuroblastoma cell growth, apoptosis and angiogenesis. J Natl Cancer Inst 2006;98:1142-1157.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1142-1157
-
-
Brignole, C.1
Marimpietri, D.2
Pastorino, F.3
Nico, B.4
Di Paolo, D.5
Cioni, M.6
Piccardi, F.7
Cilli, M.8
Pezzolo, A.9
Corrias, M.V.10
Pistoia, V.11
Ribatti, D.12
Pagnan, G.13
Ponzoni, M.14
-
5
-
-
33646789993
-
Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo
-
Michealis M, Fichtner I, Behrens D, Haider W, Rothweiler F, Mack A, Cinatl J, Doerr HW, Cinatl J Jr. Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo. Int J Oncol 2006;28:439-446.
-
(2006)
Int J Oncol
, vol.28
, pp. 439-446
-
-
Michealis, M.1
Fichtner, I.2
Behrens, D.3
Haider, W.4
Rothweiler, F.5
Mack, A.6
Cinatl, J.7
Doerr, H.W.8
Cinatl Jr., J.9
-
6
-
-
0036102867
-
S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase
-
Chiarle R, Fan Y, Piva R, Boggino H, Skolnik J, Novero D, Palestro G, De Wolf-Peeters C, Chilosi M, Pagano M, Inghirami G. S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase. Am J Pathol 2002;160:1457-1466.
-
(2002)
Am J Pathol
, vol.160
, pp. 1457-1466
-
-
Chiarle, R.1
Fan, Y.2
Piva, R.3
Boggino, H.4
Skolnik, J.5
Novero, D.6
Palestro, G.7
De Wolf-Peeters, C.8
Chilosi, M.9
Pagano, M.10
Inghirami, G.11
-
7
-
-
4444247627
-
Morphoproteomic and pharmacoproteomic correlates in hormone-receptor-negative breast carcinoma cell lines
-
Brown RE, Lun M, Prichard JW, Blasick TM, Zhang PL. Morphoproteomic and pharmacoproteomic correlates in hormone-receptor-negative breast carcinoma cell lines. Ann Clin Lab Sci 2004;34:251-262.
-
(2004)
Ann Clin Lab Sci
, vol.34
, pp. 251-262
-
-
Brown, R.E.1
Lun, M.2
Prichard, J.W.3
Blasick, T.M.4
Zhang, P.L.5
-
8
-
-
20544477463
-
Morphoproteomics: Exposing protein circuitries in tumors to identify potential therapeutic targets in cancer patients
-
Brown RE. Morphoproteomics: exposing protein circuitries in tumors to identify potential therapeutic targets in cancer patients. Expert Rev Proteomics 2005;2:337-348.
-
(2005)
Expert Rev Proteomics
, vol.2
, pp. 337-348
-
-
Brown, R.E.1
-
9
-
-
11244346968
-
Thyroid hormone induces rapid activation of Akt/ protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts
-
Cao X, Kambe F, Moeller LC, Refetoff S, Seo H. Thyroid hormone induces rapid activation of Akt/ protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. Mol Endocrinol 2005;19:102-112.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 102-112
-
-
Cao, X.1
Kambe, F.2
Moeller, L.C.3
Refetoff, S.4
Seo, H.5
-
10
-
-
0033429554
-
Mammalian target of rapamycin is a direct target for protein kinase B: Identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation
-
Nave BT, Ouwens M, Withers DJ, Alessi DR, Shepherd PR. Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem J 1999; 344:427-431.
-
(1999)
Biochem J
, vol.344
, pp. 427-431
-
-
Nave, B.T.1
Ouwens, M.2
Withers, D.J.3
Alessi, D.R.4
Shepherd, P.R.5
-
11
-
-
0032578998
-
Phosphorylation and activation of p70s6k by PDK1
-
Pullen N, Dennis PB, Andjelkovic M, Dufner A, Kozma SC, Hemmings BA, Thomas G. Phosphorylation and activation of p70s6k by PDK1. Science 1998;279:707-710.
-
(1998)
Science
, vol.279
, pp. 707-710
-
-
Pullen, N.1
Dennis, P.B.2
Andjelkovic, M.3
Dufner, A.4
Kozma, S.C.5
Hemmings, B.A.6
Thomas, G.7
-
12
-
-
0029828590
-
The principal rapamycin-sensitive p70 (s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases
-
Dennis PB, Pullen N, Kozma SC, Thomas G. The principal rapamycin-sensitive p70 (s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases. Mol Cell Biol 1996;16:6242-6251.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6242-6251
-
-
Dennis, P.B.1
Pullen, N.2
Kozma, S.C.3
Thomas, G.4
-
13
-
-
0034682763
-
Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells
-
Valentinis B, Navarro M, Zanocco-Marani T, Edmonds P, McCormick J, Morrione A, Sacchi A, Romano G, Reiss K, Baserga R. Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells. J Biol Chem 2000;275:25451-25459.
-
(2000)
J Biol Chem
, vol.275
, pp. 25451-25459
-
-
Valentinis, B.1
Navarro, M.2
Zanocco-Marani, T.3
Edmonds, P.4
McCormick, J.5
Morrione, A.6
Sacchi, A.7
Romano, G.8
Reiss, K.9
Baserga, R.10
-
14
-
-
1842852634
-
Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors
-
Xu G, Zhang W, Bertram P, Zheng XF, McLeod H. Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors. Int J Oncol 2004;24:893-900.
-
(2004)
Int J Oncol
, vol.24
, pp. 893-900
-
-
Xu, G.1
Zhang, W.2
Bertram, P.3
Zheng, X.F.4
McLeod, H.5
-
15
-
-
21244458013
-
Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site
-
Ali SM, Sabatini DM. Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005;280:19445-19448.
-
(2005)
J Biol Chem
, vol.280
, pp. 19445-19448
-
-
Ali, S.M.1
Sabatini, D.M.2
-
16
-
-
0031590007
-
Insulin stimulates p70 S6 kinase in the nucleus of cells
-
Kim SJ, Kahn CR. Insulin stimulates p70 S6 kinase in the nucleus of cells. Biochem Biophys Res Commun 1997;234:681-685.
-
(1997)
Biochem Biophys Res Commun
, vol.234
, pp. 681-685
-
-
Kim, S.J.1
Kahn, C.R.2
-
17
-
-
0035870575
-
Measurement of MAP kinase activation by flow cytometry using phosphospecific antibodies to MEK and ERK: Potential for pharmacodynamic monitoring of signal transduction inhibitors
-
Chow S, Patel H, Hedley DW. Measurement of MAP kinase activation by flow cytometry using phosphospecific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors. Cytometry 2001;46:72-78.
-
(2001)
Cytometry
, vol.46
, pp. 72-78
-
-
Chow, S.1
Patel, H.2
Hedley, D.W.3
-
18
-
-
4944249117
-
-
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.Cancer Res 2004; 64:7099-7109.
-
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.Cancer Res 2004; 64:7099-7109.
-
-
-
-
19
-
-
33744513575
-
Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature
-
Adnane L, Trail PA, Taylor I, Wilhelm SM. Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature. Meth Enzymol 2005;407:597-612.
-
(2005)
Meth Enzymol
, vol.407
, pp. 597-612
-
-
Adnane, L.1
Trail, P.A.2
Taylor, I.3
Wilhelm, S.M.4
-
20
-
-
34147161209
-
Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by Sorafenib (BAY43-9006)
-
Murphy DA, Makonnen S, Lassoued W, Feldman MD, Carter C, Lee WM. Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by Sorafenib (BAY43-9006). Am J Pathol 2006;169:1875-1885.
-
(2006)
Am J Pathol
, vol.169
, pp. 1875-1885
-
-
Murphy, D.A.1
Makonnen, S.2
Lassoued, W.3
Feldman, M.D.4
Carter, C.5
Lee, W.M.6
-
21
-
-
0028265135
-
Activation of nuclear factor kappa B in human neuroblastoma cell lines
-
Korner M, Tarantino N, Pleskoff O, Lee LM, Debre P. Activation of nuclear factor kappa B in human neuroblastoma cell lines. J Neurochem 1994:62:1716-1726.
-
(1994)
J Neurochem
, vol.62
, pp. 1716-1726
-
-
Korner, M.1
Tarantino, N.2
Pleskoff, O.3
Lee, L.M.4
Debre, P.5
-
22
-
-
0032589463
-
NF-kappaB/Rel proteins are required for neuronal differentiation of SH-SY5Y neuroblastoma cells
-
Feng Z, Porter AG. NF-kappaB/Rel proteins are required for neuronal differentiation of SH-SY5Y neuroblastoma cells. J Biol Chem 1999: 274 (43): 30341-30344.
-
(1999)
J Biol Chem
, vol.274
, Issue.43
, pp. 30341-30344
-
-
Feng, Z.1
Porter, A.G.2
-
23
-
-
0026554550
-
Flow cytometric and molecular analysis of proliferative activity and DNA content in neuroblastoma: Presence of stationary cells in S phase
-
Dominic C, Negroni A, Romeo A, McDowell H, Padula A, Pucci S, Cappelli C, Castello MA, Raschella G. Flow cytometric and molecular analysis of proliferative activity and DNA content in neuroblastoma: presence of stationary cells in S phase. Anticancer Res 1992;12:59-63.
-
(1992)
Anticancer Res
, vol.12
, pp. 59-63
-
-
Dominic, C.1
Negroni, A.2
Romeo, A.3
McDowell, H.4
Padula, A.5
Pucci, S.6
Cappelli, C.7
Castello, M.A.8
Raschella, G.9
-
24
-
-
0027751593
-
Retrospective study of prognostic value of DNA ploidy and proliferative activity in neuroblastoma
-
Huddart SN, Muir KR, Parkes SE, Mann JR, Stevens MC, Raafat F, Smith K. Retrospective study of prognostic value of DNA ploidy and proliferative activity in neuroblastoma. J Clin Pathol 1993;46:1101-1104.
-
(1993)
J Clin Pathol
, vol.46
, pp. 1101-1104
-
-
Huddart, S.N.1
Muir, K.R.2
Parkes, S.E.3
Mann, J.R.4
Stevens, M.C.5
Raafat, F.6
Smith, K.7
-
25
-
-
33748274758
-
Morphoproteomic and pharmacoproteomic rationale for mTOR effectors as therapeutic targets in head and neck squamous cell carcinoma
-
Brown RE, Zhang PL, Lun M, Zhu S, Pellitteri PK, Law A, Riefkohl W, Wood GC, Kennedy TL. Morphoproteomic and pharmacoproteomic rationale for mTOR effectors as therapeutic targets in head and neck squamous cell carcinoma. Ann Clin Lab Sci 2006;36:273-282.
-
(2006)
Ann Clin Lab Sci
, vol.36
, pp. 273-282
-
-
Brown, R.E.1
Zhang, P.L.2
Lun, M.3
Zhu, S.4
Pellitteri, P.K.5
Law, A.6
Riefkohl, W.7
Wood, G.C.8
Kennedy, T.L.9
-
26
-
-
0036605053
-
Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines
-
Bancroft CC, Chen Z, Yeh J, Sunwoo JB, Yeh NT, Jackson S, Jackson C, Van Waes C. Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. Int J Cancer 2002;99:538-548.
-
(2002)
Int J Cancer
, vol.99
, pp. 538-548
-
-
Bancroft, C.C.1
Chen, Z.2
Yeh, J.3
Sunwoo, J.B.4
Yeh, N.T.5
Jackson, S.6
Jackson, C.7
Van Waes, C.8
-
27
-
-
18944399076
-
Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappaB-regulated gene products
-
Ichikawa H, Takada Y, Murakami A, Aggarwal BB. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappaB-regulated gene products. J Immunol 2005;174:7383-7392.
-
(2005)
J Immunol
, vol.174
, pp. 7383-7392
-
-
Ichikawa, H.1
Takada, Y.2
Murakami, A.3
Aggarwal, B.B.4
-
28
-
-
33748254960
-
Morphoproteomic and molecular concomitants of an overexpressed and activated mTOR pathway in renal cell carcinomas
-
Lin F, Zhang PL, Yang XJ, Prichard JW, Lun M, Brown RE. Morphoproteomic and molecular concomitants of an overexpressed and activated mTOR pathway in renal cell carcinomas. Ann Clin Lab Sci 2006;36:283-293.
-
(2006)
Ann Clin Lab Sci
, vol.36
, pp. 283-293
-
-
Lin, F.1
Zhang, P.L.2
Yang, X.J.3
Prichard, J.W.4
Lun, M.5
Brown, R.E.6
-
29
-
-
18244396614
-
Sensitivity to gemcitabine and its metabolizing enzymes in neuroblastoma
-
Ogawa M, Hori H, Ohta T, Onozato K, Miyahara M, Komada Y. Sensitivity to gemcitabine and its metabolizing enzymes in neuroblastoma. Clin Cancer Res 2005; 11:3485-3493.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3485-3493
-
-
Ogawa, M.1
Hori, H.2
Ohta, T.3
Onozato, K.4
Miyahara, M.5
Komada, Y.6
-
30
-
-
31544464043
-
Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma
-
Chun PY, Feng FY, Scheurer AM, Davis MA, Lawrence TS, Nyati MK Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma. Cancer Res 2006;66:981-988.
-
(2006)
Cancer Res
, vol.66
, pp. 981-988
-
-
Chun, P.Y.1
Feng, F.Y.2
Scheurer, A.M.3
Davis, M.A.4
Lawrence, T.S.5
Nyati, M.K.6
-
31
-
-
33646834444
-
MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening
-
Iehara T, Hosoi H, Akazawa K, Matsumoto Y, Yamamoto K, Suita S, Tajiri T, Kusafuka T, Hiyama E, Kaneko M, Sasaki F, Sugimoto T, Sawada T. MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening. Br J Cancer 2006;94:1510-1515.
-
(2006)
Br J Cancer
, vol.94
, pp. 1510-1515
-
-
Iehara, T.1
Hosoi, H.2
Akazawa, K.3
Matsumoto, Y.4
Yamamoto, K.5
Suita, S.6
Tajiri, T.7
Kusafuka, T.8
Hiyama, E.9
Kaneko, M.10
Sasaki, F.11
Sugimoto, T.12
Sawada, T.13
-
32
-
-
0345711633
-
N-myc regulation of type I insulin-like growth factor receptor in a human neuroblastoma cell line
-
Chambery D, Mohseni-Zadeh S, de Galle B, Babajko S. N-myc regulation of type I insulin-like growth factor receptor in a human neuroblastoma cell line. Cancer Res 1999;59:2898-2902.
-
(1999)
Cancer Res
, vol.59
, pp. 2898-2902
-
-
Chambery, D.1
Mohseni-Zadeh, S.2
de Galle, B.3
Babajko, S.4
-
33
-
-
0034741959
-
Bcl-2 and M-Myc coexpression increases IGF-IR and features of malignant growth in neuroblastoma cell lines
-
Jasty R, van Golen C, Lin HJ, Solomon G, Heidelberger K, Polverini P, Opipari A, Feldman E, Castle VP. Bcl-2 and M-Myc coexpression increases IGF-IR and features of malignant growth in neuroblastoma cell lines. Neoplasia 2001;3:304-313.
-
(2001)
Neoplasia
, vol.3
, pp. 304-313
-
-
Jasty, R.1
van Golen, C.2
Lin, H.J.3
Solomon, G.4
Heidelberger, K.5
Polverini, P.6
Opipari, A.7
Feldman, E.8
Castle, V.P.9
-
34
-
-
0033958740
-
N-Myc induction stimulated by insulin-like growth factor I through mitogen-activated protein kinase signaling pathway in human neuroblastoma cells
-
Misawa A, Hosoi H, Arimoto A, Shikata T, Akioka S, Matsumura T, Houghton PJ, Sawada T. N-Myc induction stimulated by insulin-like growth factor I through mitogen-activated protein kinase signaling pathway in human neuroblastoma cells. Cancer Res 2000;60:64-69.
-
(2000)
Cancer Res
, vol.60
, pp. 64-69
-
-
Misawa, A.1
Hosoi, H.2
Arimoto, A.3
Shikata, T.4
Akioka, S.5
Matsumura, T.6
Houghton, P.J.7
Sawada, T.8
-
35
-
-
0036875706
-
Induction of N-myc in neuroblastoma by autocrine IGF-II depends on farnesylated Ras. Application of farnesyltransferase inhibitors
-
Wittrock J, Schweizer P, Girgert R. Induction of N-myc in neuroblastoma by autocrine IGF-II depends on farnesylated Ras. Application of farnesyltransferase inhibitors. Anticancer Res 2002;22:4205-4209.
-
(2002)
Anticancer Res
, vol.22
, pp. 4205-4209
-
-
Wittrock, J.1
Schweizer, P.2
Girgert, R.3
-
36
-
-
2942593696
-
Upregulation of macrophage migration inhibitory factor contributes to induced N-Myc expression by the activation of ERK signaling pathway and increased expression of interleukin-8 and VEGF in neuroblastoma
-
Ren Y, Chan HM, Li Z, Lin C, Nicholls J, Chen CF, Lee PY, Lui V, Bacher M, Tam PK. Upregulation of macrophage migration inhibitory factor contributes to induced N-Myc expression by the activation of ERK signaling pathway and increased expression of interleukin-8 and VEGF in neuroblastoma. Oncogene 2004;23:4146-4154.
-
(2004)
Oncogene
, vol.23
, pp. 4146-4154
-
-
Ren, Y.1
Chan, H.M.2
Li, Z.3
Lin, C.4
Nicholls, J.5
Chen, C.F.6
Lee, P.Y.7
Lui, V.8
Bacher, M.9
Tam, P.K.10
-
37
-
-
33745193454
-
-
Spitz R, Hero B, Simon T, Berthold F. Loss in chromosome 11q identifies tumors with increased risk for metastatic relapses in localized and 4S neuroblastoma. Clin Cancer Res 2006;12:3368-3373.
-
Spitz R, Hero B, Simon T, Berthold F. Loss in chromosome 11q identifies tumors with increased risk for metastatic relapses in localized and 4S neuroblastoma. Clin Cancer Res 2006;12:3368-3373.
-
-
-
-
38
-
-
0025357929
-
Mapping of a gene determining tuberous sclerosis to human chromosome 11q14-11q23
-
Smith M, Smalley S, Cantor R, Pandolfo M, Gomez MI, Baumann R, Flodman P, Yoshiyama K, Nakamura Y, Julier C, Dumars K, Haines J, Trofatter J, Spence MA, Weeks D, Conneally M. Mapping of a gene determining tuberous sclerosis to human chromosome 11q14-11q23. Genomics 1990;6:105-114.
-
(1990)
Genomics
, vol.6
, pp. 105-114
-
-
Smith, M.1
Smalley, S.2
Cantor, R.3
Pandolfo, M.4
Gomez, M.I.5
Baumann, R.6
Flodman, P.7
Yoshiyama, K.8
Nakamura, Y.9
Julier, C.10
Dumars, K.11
Haines, J.12
Trofatter, J.13
Spence, M.A.14
Weeks, D.15
Conneally, M.16
-
39
-
-
0024998204
-
Genetic heterogeneity in tuberous sclerosis
-
Janssen LA, Sandkuyl LA, Merkens EC, Maat-Kievit JA, Sampson JR, Fleury P, Hennekam RC, Grosveld GC, Lindhout D, Halley DJ. Genetic heterogeneity in tuberous sclerosis. Genomics 1990;8:237-242.
-
(1990)
Genomics
, vol.8
, pp. 237-242
-
-
Janssen, L.A.1
Sandkuyl, L.A.2
Merkens, E.C.3
Maat-Kievit, J.A.4
Sampson, J.R.5
Fleury, P.6
Hennekam, R.C.7
Grosveld, G.C.8
Lindhout, D.9
Halley, D.J.10
-
40
-
-
0042701991
-
Tuberous sclerosis complex gene products, tuberin and hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
-
Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J. Tuberous sclerosis complex gene products, tuberin and hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr Biol 2003;13:1259-1268.
-
(2003)
Curr Biol
, vol.13
, pp. 1259-1268
-
-
Tee, A.R.1
Manning, B.D.2
Roux, P.P.3
Cantley, L.C.4
Blenis, J.5
-
41
-
-
33750976204
-
Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors
-
Ryan DP, Appleman LJ, Lynch T, Supko JG, Fidias P, Clark JW, Fishman M, Zhu AX, Enzinger PC, Kashala O, Cusack J Jr, Eder JP. Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors. Cancer 2006;107:2482-2489.
-
(2006)
Cancer
, vol.107
, pp. 2482-2489
-
-
Ryan, D.P.1
Appleman, L.J.2
Lynch, T.3
Supko, J.G.4
Fidias, P.5
Clark, J.W.6
Fishman, M.7
Zhu, A.X.8
Enzinger, P.C.9
Kashala, O.10
Cusack Jr, J.11
Eder, J.P.12
-
42
-
-
0030808855
-
Possible involvement of rapamycin-sensitive pathway in Bcl-2 expression in human neuroblastoma SH-SY5Y cells
-
Kitamura Y, Kosaka T, Shimohama S, Nomura Y, Taniguchi T. Possible involvement of rapamycin-sensitive pathway in Bcl-2 expression in human neuroblastoma SH-SY5Y cells. Jpn J Pharmacol 1997; 75:195-198.
-
(1997)
Jpn J Pharmacol
, vol.75
, pp. 195-198
-
-
Kitamura, Y.1
Kosaka, T.2
Shimohama, S.3
Nomura, Y.4
Taniguchi, T.5
-
43
-
-
0034783746
-
Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect
-
Calastretti A, Rancati F, Ceriani MC, Asnaghi L, Canti G, Nicolin A. Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect. Eur J Cancer 2001;37:2121-2128.
-
(2001)
Eur J Cancer
, vol.37
, pp. 2121-2128
-
-
Calastretti, A.1
Rancati, F.2
Ceriani, M.C.3
Asnaghi, L.4
Canti, G.5
Nicolin, A.6
-
44
-
-
5044240387
-
Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway
-
Chang GC, Hsu SL, Tsai JR, Wu WJ, Chen CY, Sheu GT. Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway. Eur J Pharmacol 2004;502:169-183.
-
(2004)
Eur J Pharmacol
, vol.502
, pp. 169-183
-
-
Chang, G.C.1
Hsu, S.L.2
Tsai, J.R.3
Wu, W.J.4
Chen, C.Y.5
Sheu, G.T.6
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