Coenzyme Q10 - Its role as a prooxidant in the formation of superoxide anion/hydrogen peroxide and the regulation of the metabolome

Mitochondrion

Volumn 7, Issue SUPPL., 2007, Pages

  Linnane, Anthony W ^a   Kios, Michael ^a   Vitetta, Luis ^a  

^a EPWORTH HOSPITAL   (Australia)

Author keywords

Coenzyme Q10; Hydrogen peroxide; Metabolome; Prooxidant; Second messenger; Superoxide anions

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ACONITATE HYDRATASE; ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; CATHEPSIN; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C OXIDASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYDROGEN PEROXIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; PLACEBO; PROTEIN C JUN; PROTEIN FOS; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE; SUPEROXIDE DISMUTASE; UBIDECARENONE; UBIQUINOL CYTOCHROME C REDUCTASE; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER; CELL AGING; CELL MEMBRANE; CELL SURVIVAL; CLINICAL TRIAL; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENE SILENCING; GOLGI COMPLEX; HEART DISEASE; HEART MITOCHONDRION; HUMAN; LYSOSOME; METABOLIC REGULATION; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL ENERGY TRANSFER; MUSCLE MITOCHONDRION; NEUROLOGIC DISEASE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTON MOTIVE FORCE; PROTON TRANSPORT; SECOND MESSENGER; SECRETORY GRANULE; SIGNAL TRANSDUCTION; SKIN INJURY; TRANSCRIPTION REGULATION;

ANIMALS; ANIONS; ANTIOXIDANTS; CELL MEMBRANE; COENZYMES; DNA, MITOCHONDRIAL; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; MITOCHONDRIA; MODELS, BIOLOGICAL; OXIDANTS; SIGNAL TRANSDUCTION; SUPEROXIDES; UBIQUINONE;

MAMMALIA;

EID: 34248184025     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2007.03.005     Document Type: Article

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