-
1
-
-
0032483419
-
The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
-
Ganju RK, Brubaker SA, Meyer J, et al. The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem 1998;273:23169-75.
-
(1998)
J Biol Chem
, vol.273
, pp. 23169-23175
-
-
Ganju, R.K.1
Brubaker, S.A.2
Meyer, J.3
-
2
-
-
20444383082
-
Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1α in the circulation
-
Davis DA, Singer DE, Sierra DM, et al. Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1α in the circulation. Blood 2005;105:4561-8.
-
(2005)
Blood
, vol.105
, pp. 4561-4568
-
-
Davis, D.A.1
Singer, D.E.2
Sierra, D.M.3
-
3
-
-
1642366238
-
Differential processing of stromal-derived factor-1α and stromal-derived factor-1β explains functional diversity
-
De La LuzSierra M, Yang F, Narazaki M, et al. Differential processing of stromal-derived factor-1α and stromal-derived factor-1β explains functional diversity. Blood 2004;103:2452-9.
-
(2004)
Blood
, vol.103
, pp. 2452-2459
-
-
De La LuzSierra, M.1
Yang, F.2
Narazaki, M.3
-
4
-
-
0034656351
-
Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: Roles of phosphoinositide-3 kinase and protein kinase C
-
Wang JF, Park IW, Groopman JE. Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C. Blood 2000;95:2505-13.
-
(2000)
Blood
, vol.95
, pp. 2505-2513
-
-
Wang, J.F.1
Park, I.W.2
Groopman, J.E.3
-
5
-
-
0028324454
-
Molecular cloning and structure of a pre-B-cell growth stimulating factor
-
Nagasawa T, Kikutani H, Kishimoto T. Molecular cloning and structure of a pre-B-cell growth stimulating factor. Proc Natl Acad Sci U S A 1994;91:2305-9.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 2305-2309
-
-
Nagasawa, T.1
Kikutani, H.2
Kishimoto, T.3
-
6
-
-
0742289555
-
Homing and mobilization of hematopoietic stem cells and hematopoietic cancer cells are mirror image processes, utilizing similar signaling pathways and occurring concurrently: Circulating cancer cells constitute an ideal target for concurrent treatment with chemotherapy and anti-lineage specific antibodies
-
Gazitt Y. Homing and mobilization of hematopoietic stem cells and hematopoietic cancer cells are mirror image processes, utilizing similar signaling pathways and occurring concurrently: circulating cancer cells constitute an ideal target for concurrent treatment with chemotherapy and anti-lineage specific antibodies. Leukemia 2004;18:1-10.
-
(2004)
Leukemia
, vol.18
, pp. 1-10
-
-
Gazitt, Y.1
-
7
-
-
33846932064
-
Stromal derived growth factor-1α: Another mediator in neural-emerging immune system through Tac1 expression in bone marrow stromal cells
-
Corcoran KE, Patel N, Rameshwar P. Stromal derived growth factor-1α: another mediator in neural-emerging immune system through Tac1 expression in bone marrow stromal cells. J Immunol 2007;178:2075-82.
-
(2007)
J Immunol
, vol.178
, pp. 2075-2082
-
-
Corcoran, K.E.1
Patel, N.2
Rameshwar, P.3
-
8
-
-
0034602721
-
Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: Implications for BM metastasis
-
Singh D, Joshi DD, Hameed M, et al. Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for BM metastasis. Proc Natl Acad Sci U S A 2000;97:388-93.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 388-393
-
-
Singh, D.1
Joshi, D.D.2
Hameed, M.3
-
9
-
-
0036157658
-
Pharmacological profile of the novel mammalian tachykinin, hemokinin 1
-
Bellucci F, Carini F, Catalani C, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol 2002;135:266-74.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 266-274
-
-
Bellucci, F.1
Carini, F.2
Catalani, C.3
-
10
-
-
2442641847
-
Tachykinins in the emerging immune system: Relevance to bone marrow homeostasis and maintenance of hematopoietic stem cells
-
Greco SJ, Corcoran KE, Trzaska KA, Rameshwar P. Tachykinins in the emerging immune system: relevance to bone marrow homeostasis and maintenance of hematopoietic stem cells. Front Biosci 2004;9:1782-93.
-
(2004)
Front Biosci
, vol.9
, pp. 1782-1793
-
-
Greco, S.J.1
Corcoran, K.E.2
Trzaska, K.A.3
Rameshwar, P.4
-
12
-
-
33747451723
-
The expression of neurokinin-1 and preprotachykinin-1 in breast cancer cells depends on the relative degree of invasive and metastatic potential
-
Castro TA, Cohen MC, Rameshwar P. The expression of neurokinin-1 and preprotachykinin-1 in breast cancer cells depends on the relative degree of invasive and metastatic potential. Clin Exp Metastasis 2005;22:621-8.
-
(2005)
Clin Exp Metastasis
, vol.22
, pp. 621-628
-
-
Castro, T.A.1
Cohen, M.C.2
Rameshwar, P.3
-
13
-
-
0037622168
-
Crosstalk between neurokinin receptors is relevant to hematopoietic regulation: Cloning and characterization of neurokinin-2 promoter
-
Bandari PS, Qian J, Oh HS, et al. Crosstalk between neurokinin receptors is relevant to hematopoietic regulation: cloning and characterization of neurokinin-2 promoter. J Neuroimmunol 2003;138:65-75.
-
(2003)
J Neuroimmunol
, vol.138
, pp. 65-75
-
-
Bandari, P.S.1
Qian, J.2
Oh, H.S.3
-
14
-
-
4344718326
-
Facilitating role of preprotachykinin-I gene in the integration of breast cancer cells within the stromal compartment of the bone marrow: A model of early cancer progression
-
Rao G, Patel PS, Idler SP, et al. Facilitating role of preprotachykinin-I gene in the integration of breast cancer cells within the stromal compartment of the bone marrow: a model of early cancer progression. Cancer Res 2004;64:6327-31.
-
(2004)
Cancer Res
, vol.64
, pp. 6327-6331
-
-
Rao, G.1
Patel, P.S.2
Idler, S.P.3
-
15
-
-
4344647262
-
Bone marrow stroma influences transforming growth factor-β production in breast cancer cells to regulate c-myc activation of the preprotachykinin-I gene in breast cancer cells
-
Oh HS, Moharita A, Potian JG, et al. Bone marrow stroma influences transforming growth factor-β production in breast cancer cells to regulate c-myc activation of the preprotachykinin-I gene in breast cancer cells. Cancer Res 2004;64:6327-36.
-
(2004)
Cancer Res
, vol.64
, pp. 6327-6336
-
-
Oh, H.S.1
Moharita, A.2
Potian, J.G.3
-
16
-
-
28444445706
-
Neurokinin receptors and subtypes as potential targets in breast cancer: Relevance to bone marrow metastasis
-
Moharita A, Harrison JS, Rameshwar P. Neurokinin receptors and subtypes as potential targets in breast cancer: relevance to bone marrow metastasis. Drug Des Rev Online 2004;1:297-302.
-
(2004)
Drug Des Rev Online
, vol.1
, pp. 297-302
-
-
Moharita, A.1
Harrison, J.S.2
Rameshwar, P.3
-
17
-
-
20144369596
-
Autocrine proliferation of neuroblastoma cells is partly mediated through neurokinin receptors: Relevance to bone marrow metastasis
-
Mukerji I, Ramkissoon SH, Reddy KK, Rameshwar P. Autocrine proliferation of neuroblastoma cells is partly mediated through neurokinin receptors: relevance to bone marrow metastasis. J Neurooncol 2005;71:91-8.
-
(2005)
J Neurooncol
, vol.71
, pp. 91-98
-
-
Mukerji, I.1
Ramkissoon, S.H.2
Reddy, K.K.3
Rameshwar, P.4
-
18
-
-
0032005849
-
Enhanced expression of neuropeptides in human breast cancer cell lines following irradiation
-
Aalto Y, Forsgren S, Kjorell U, Bergh J, Franzen L, Henriksson R. Enhanced expression of neuropeptides in human breast cancer cell lines following irradiation. Peptides 1998;19:231-9.
-
(1998)
Peptides
, vol.19
, pp. 231-239
-
-
Aalto, Y.1
Forsgren, S.2
Kjorell, U.3
Bergh, J.4
Franzen, L.5
Henriksson, R.6
-
19
-
-
0035887889
-
Induction of hypoxia-inducible factor-1α and activation of caspase-3 in hypoxia-reoxygenated bone marrow stroma is negatively regulated by the delayed production of substance P
-
Qian J, Ramroop K, McLeod A, et al. Induction of hypoxia-inducible factor-1α and activation of caspase-3 in hypoxia-reoxygenated bone marrow stroma is negatively regulated by the delayed production of substance P. J Immunol 2001;167:4600-8.
-
(2001)
J Immunol
, vol.167
, pp. 4600-4608
-
-
Qian, J.1
Ramroop, K.2
McLeod, A.3
-
20
-
-
0030002160
-
Induction of negative hematopoietic regulators by neurokinin-A in bone marrow stroma
-
Rameshwar P, Gascon P. Induction of negative hematopoietic regulators by neurokinin-A in bone marrow stroma. Blood 1996;88:98-106.
-
(1996)
Blood
, vol.88
, pp. 98-106
-
-
Rameshwar, P.1
Gascon, P.2
-
21
-
-
0027281553
-
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists
-
Fan TP, Hu DE, Guard S, Gresham GA, Watling KJ. Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists. Br J Pharmacol 1993;110:43-9.
-
(1993)
Br J Pharmacol
, vol.110
, pp. 43-49
-
-
Fan, T.P.1
Hu, D.E.2
Guard, S.3
Gresham, G.A.4
Watling, K.J.5
-
22
-
-
28444459876
-
Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-I peptides
-
Patel H, Ramkissoon SH, Patel PS, Rameshwar P. Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-I peptides. Proc Natl Acad Sci U S A 2005;102:17436-41.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 17436-17441
-
-
Patel, H.1
Ramkissoon, S.H.2
Patel, P.S.3
Rameshwar, P.4
-
23
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-6.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
-
24
-
-
0141685979
-
Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma
-
Kato M, Kitayama J, Kazama S, Nagawa H. Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma. Breast Cancer Res 2003;5:R144-50.
-
(2003)
Breast Cancer Res
, vol.5
-
-
Kato, M.1
Kitayama, J.2
Kazama, S.3
Nagawa, H.4
-
25
-
-
2942692286
-
CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer
-
Mori T, Doi R, Koizumi M, et al. CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer. Mol Cancer Ther 2004;3:29-37.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 29-37
-
-
Mori, T.1
Doi, R.2
Koizumi, M.3
-
26
-
-
33751189144
-
SDF-1α regulation in breast cancer cells contacting bone marrow stroma is critical for normal hematopoiesis
-
Moharita AL, Taborga M, Corcoran KE, Bryan M, Patel PS, Rameshwar P. SDF-1α regulation in breast cancer cells contacting bone marrow stroma is critical for normal hematopoiesis. Blood 2006;108:3245-52.
-
(2006)
Blood
, vol.108
, pp. 3245-3252
-
-
Moharita, A.L.1
Taborga, M.2
Corcoran, K.E.3
Bryan, M.4
Patel, P.S.5
Rameshwar, P.6
-
27
-
-
10844288136
-
CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo
-
Lapteva N, Yang AG, Strube RW, Sanders DE. CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo. Cancer Gene Ther 2005;12:84-9.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 84-89
-
-
Lapteva, N.1
Yang, A.G.2
Strube, R.W.3
Sanders, D.E.4
-
28
-
-
0035865194
-
Cloning of human preprotachykinin-I promoter and the role of cyclic adenosine 5′-monophosphate response elements in its expression by IL-1 and stem cell factor
-
Qian J, Yehia G, Molina C, et al. Cloning of human preprotachykinin-I promoter and the role of cyclic adenosine 5′-monophosphate response elements in its expression by IL-1 and stem cell factor. J Immunol 2001;166:2553-61.
-
(2001)
J Immunol
, vol.166
, pp. 2553-2561
-
-
Qian, J.1
Yehia, G.2
Molina, C.3
-
29
-
-
0031112418
-
Receptor induction regulates the synergistic effects of substance P with IL-1 and PDGF on the proliferation of bone marrow fibroblasts
-
Rameshwar P, Poddar A, Zhu G, Gascon P. Receptor induction regulates the synergistic effects of substance P with IL-1 and PDGF on the proliferation of bone marrow fibroblasts. J Immunol 1997;158:3417-24.
-
(1997)
J Immunol
, vol.158
, pp. 3417-3424
-
-
Rameshwar, P.1
Poddar, A.2
Zhu, G.3
Gascon, P.4
-
30
-
-
0037438505
-
Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling
-
Roland J, Murphy BJ, Ahr B, et al. Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling. Blood 2003;101:399-406.
-
(2003)
Blood
, vol.101
, pp. 399-406
-
-
Roland, J.1
Murphy, B.J.2
Ahr, B.3
-
31
-
-
27144443385
-
Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells
-
Dar A, Goichberg P, Shinder V, et al. Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells. Nat Immunol 2005;6:1038-46.
-
(2005)
Nat Immunol
, vol.6
, pp. 1038-1046
-
-
Dar, A.1
Goichberg, P.2
Shinder, V.3
-
32
-
-
0033486065
-
The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes
-
Sotsios Y, Whittaker GC, Westwick J, Ward SG. The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. J Immunol 1999;163:5954-63.
-
(1999)
J Immunol
, vol.163
, pp. 5954-5963
-
-
Sotsios, Y.1
Whittaker, G.C.2
Westwick, J.3
Ward, S.G.4
-
33
-
-
0942276399
-
CXCL16 signals via Gi, phosphatidylinositol 3-kinase, Akt, IκB kinase, and nuclear factor-κB and induces cell-cell adhesion and aortic smooth muscle cell proliferation
-
Chandrasekar B, Bysani S, Mummidi S. CXCL16 signals via Gi, phosphatidylinositol 3-kinase, Akt, IκB kinase, and nuclear factor-κB and induces cell-cell adhesion and aortic smooth muscle cell proliferation. J Biol Chem 2004;279:3188-96.
-
(2004)
J Biol Chem
, vol.279
, pp. 3188-3196
-
-
Chandrasekar, B.1
Bysani, S.2
Mummidi, S.3
-
34
-
-
23944466427
-
A pooled analysis of bone marrow micrometastasis in breast cancer
-
Braun S, Vogl FD, Naume B, et al. A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med 2005;353:793-802.
-
(2005)
N Engl J Med
, vol.353
, pp. 793-802
-
-
Braun, S.1
Vogl, F.D.2
Naume, B.3
-
35
-
-
23244435467
-
How do stem cells find their way home?
-
Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood 2005;106:1901-10.
-
(2005)
Blood
, vol.106
, pp. 1901-1910
-
-
Lapidot, T.1
Dar, A.2
Kollet, O.3
-
36
-
-
23844513413
-
Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
-
Kucia M, Reca R, Miekus K, et al. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 2005;7:879-94.
-
(2005)
Stem Cells
, vol.7
, pp. 879-894
-
-
Kucia, M.1
Reca, R.2
Miekus, K.3
-
37
-
-
0036302147
-
G-CSF induces stem cell mobilization by decreasing in bone marrow SDF-1 and up-regulating CXCR4
-
Petit I, Szyper-Kravitz M, Nagler A, et al. G-CSF induces stem cell mobilization by decreasing in bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol 2002;3:687-94.
-
(2002)
Nat Immunol
, vol.3
, pp. 687-694
-
-
Petit, I.1
Szyper-Kravitz, M.2
Nagler, A.3
-
38
-
-
0038498102
-
NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4
-
Helbig G, Christopherson KW, Bhat-Nakshatri P, et al. NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Biol Chem 2003;278:21631-8.
-
(2003)
J Biol Chem
, vol.278
, pp. 21631-21638
-
-
Helbig, G.1
Christopherson, K.W.2
Bhat-Nakshatri, P.3
-
39
-
-
0036546501
-
NF-κB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR, Li ZW. NF-κB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002;4:301-10.
-
(2002)
Nat Rev Cancer
, vol.4
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
40
-
-
33750325725
-
S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
-
Dorrello NV, Peschiaroli A, Guardavaccaro D, Colburn NH, Sherman NE, Pagano M. S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 2006;314:467-71.
-
(2006)
Science
, vol.314
, pp. 467-471
-
-
Dorrello, N.V.1
Peschiaroli, A.2
Guardavaccaro, D.3
Colburn, N.H.4
Sherman, N.E.5
Pagano, M.6
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