Development and validation of a sensitive reversed-phase HPLC method to determine intracellular accumulation of hydroxycamptothecin

Journal of Pharmaceutical and Biomedical Analysis

Volumn 41, Issue 3, 2006, Pages 1007-1010

  Zhao, Yong Xing ^a,b   Gao, Jian Qing ^a   Qiao, Hai Ling ^b   Chen, Hai Liang ^a   Liang, Wen Quan ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHENGZHOU UNIVERSITY   (China)

Author keywords

Cells; Determination; High performance liquid chromatography; Hydroxycamptothecin; Liposomes

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETONITRILE; BUFFER; CAMPTOTHECIN; HYDROXYCAMPTOTHECIN; LIPOSOME; PHOSPHORIC ACID; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CORRELATION COEFFICIENT; CYTOLYSIS; DRUG ACCUMULATION; DRUG DETERMINATION; ESOPHAGUS CANCER; EXTRACTION; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; INCUBATION TIME; PH; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

CALIBRATION; CAMPTOTHECIN; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE;

EID: 33646403692     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.01.009     Document Type: Article

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