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Volumn 69, Issue 3, 2007, Pages 227-235

A functional Fas promoter polymorphism is associated with a severe phenotype in type 1 autoimmune hepatitis characterized by early development of cirrhosis

Author keywords

Apoptosis; Autoimmunity; Complex disease; Fas; Genetics; Immune regulation; Polymerase chain reaction; TNFRSF6; Type 1 autoimmune hepatitis

Indexed keywords

ADENOSINE; ASPARTATE AMINOTRANSFERASE; AZATHIOPRINE; FAS ANTIGEN; GUANINE; HLA ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; PREDNISONE;

EID: 34247882930     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2006.00794.x     Document Type: Article
Times cited : (78)

References (65)
  • 1
    • 0031941458 scopus 로고    scopus 로고
    • Incidence and prevalence of primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis in a Norwegian population
    • Boberg KM, Aadland E, Jahnsen J, Raknerud N, Stiris M, Bell H. Incidence and prevalence of primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis in a Norwegian population. Scand J Gastroenterol 1998 : 33 : 99 103.
    • (1998) Scand J Gastroenterol , vol.33 , pp. 99-103
    • Boberg, K.M.1    Aadland, E.2    Jahnsen, J.3    Raknerud, N.4    Stiris, M.5    Bell, H.6
  • 2
    • 0025904366 scopus 로고
    • Susceptibility to autoimmune chronic active hepatitis: Human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors
    • Donaldson PT, Doherty DG, Hayllar KM, McFarlane IG, Johnson PJ, Williams R. Susceptibility to autoimmune chronic active hepatitis: human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors. Hepatology 1991 : 13 : 701 6.
    • (1991) Hepatology , vol.13 , pp. 701-6
    • Donaldson, P.T.1    Doherty, D.G.2    Hayllar, K.M.3    McFarlane, I.G.4    Johnson, P.J.5    Williams, R.6
  • 3
    • 0030962578 scopus 로고    scopus 로고
    • Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis
    • Strettell MDJ, Donaldson PT, Thompson LJ et al. Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis. Gastroenterology 1997 : 112 : 2028 35.
    • (1997) Gastroenterology , vol.112 , pp. 2028-35
    • Strettell, M.D.J.1    Donaldson, P.T.2    Thompson, L.J.3
  • 4
    • 0028091080 scopus 로고
    • Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis
    • Doherty DG, Donaldson PT, Underhill JA et al. Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis. Hepatology 1994 : 19 : 609 15.
    • (1994) Hepatology , vol.19 , pp. 609-15
    • Doherty, D.G.1    Donaldson, P.T.2    Underhill, J.A.3
  • 6
    • 0032544004 scopus 로고    scopus 로고
    • Clustering of non-major histocompatibility complex susceptibility loci in human autoimmune diseases
    • Becker KG, Simon RM, Bailey-Wilson JE et al. Clustering of non-major histocompatibility complex susceptibility loci in human autoimmune diseases. Proc Natl Acad Sci USA 1998 : 95 : 9979 84.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9979-84
    • Becker, K.G.1    Simon, R.M.2    Bailey-Wilson, J.E.3
  • 7
    • 0033032379 scopus 로고    scopus 로고
    • Comparative genetics of type 1 diabetes and autoimmune disease
    • Becker KG. Comparative genetics of type 1 diabetes and autoimmune disease. Diabetes 1999 : 48 : 1353 8.
    • (1999) Diabetes , vol.48 , pp. 1353-8
    • Becker, K.G.1
  • 8
    • 0034077771 scopus 로고    scopus 로고
    • Genetic susceptibilities for immune expression and liver cell injury in autoimmune hepatitis
    • Czaja AJ, Donaldson PT. Genetic susceptibilities for immune expression and liver cell injury in autoimmune hepatitis. Immunol Rev 2000 : 174 : 250 9.
    • (2000) Immunol Rev , vol.174 , pp. 250-9
    • Czaja, A.J.1    Donaldson, P.T.2
  • 9
    • 0036851351 scopus 로고    scopus 로고
    • Genetics of autoimmune hepatitis
    • Donaldson PT. Genetics of autoimmune hepatitis. Semin Liver Dis 2002 : 22 : 353 63.
    • (2002) Semin Liver Dis , vol.22 , pp. 353-63
    • Donaldson, P.T.1
  • 10
    • 0032862558 scopus 로고    scopus 로고
    • Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis
    • Cookson S, Constantini PK, Clare M et al. Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis. Hepatology 1999 : 30 : 851 6.
    • (1999) Hepatology , vol.30 , pp. 851-6
    • Cookson, S.1    Constantini, P.K.2    Clare, M.3
  • 11
    • 0032819862 scopus 로고    scopus 로고
    • Cytokine polymorphisms associated with clinical features and treatment outcome in type 1 autoimmune hepatitis
    • Czaja AJ, Cookson S, Constantini PK, Clare M, Underhill JA, Donaldson PT. Cytokine polymorphisms associated with clinical features and treatment outcome in type 1 autoimmune hepatitis. Gastroenterology 1999 : 117 : 645 52.
    • (1999) Gastroenterology , vol.117 , pp. 645-52
    • Czaja, A.J.1    Cookson, S.2    Constantini, P.K.3    Clare, M.4    Underhill, J.A.5    Donaldson, P.T.6
  • 12
    • 0033962893 scopus 로고    scopus 로고
    • CTLA-4 polymorphisms and susceptibility to type 1 autoimmune hepatitis
    • Agarwal K, Czaja AJ, Jones DEJ, Donaldson PT. CTLA-4 polymorphisms and susceptibility to type 1 autoimmune hepatitis. Hepatology 2000 : 31 : 49 53.
    • (2000) Hepatology , vol.31 , pp. 49-53
    • Agarwal, K.1    Czaja, A.J.2    Jones, D.E.J.3    Donaldson, P.T.4
  • 13
    • 0032734010 scopus 로고    scopus 로고
    • Apoptotic and effector pathways in autoimmunity
    • Chervonsky AV. Apoptotic and effector pathways in autoimmunity. Curr Opin Immunol 1999 : 11 : 684 8.
    • (1999) Curr Opin Immunol , vol.11 , pp. 684-8
    • Chervonsky, A.V.1
  • 14
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot J-P, Chamaillard M, Zouali H et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001 : 411 : 599 603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.-P.1    Chamaillard, M.2    Zouali, H.3
  • 15
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001 : 411 : 603 6.
    • (2001) Nature , vol.411 , pp. 603-6
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3
  • 16
    • 0035978779 scopus 로고    scopus 로고
    • Tackling common disease
    • Todd JA. Tackling common disease. Nature 2001 : 411 : 537 9.
    • (2001) Nature , vol.411 , pp. 537-9
    • Todd, J.A.1
  • 17
    • 0035897904 scopus 로고    scopus 로고
    • Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
    • Hampe J, Cuthbert A, Croucher PJP et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001 : 357 : 1925 8.
    • (2001) Lancet , vol.357 , pp. 1925-8
    • Hampe, J.1    Cuthbert, A.2    Croucher, P.J.P.3
  • 18
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. Apoptosis by death factor. Cell 1997 : 88 : 355 65.
    • (1997) Cell , vol.88 , pp. 355-65
    • Nagata, S.1
  • 20
    • 0025675497 scopus 로고
    • T-cell directed hepatocyte damage in autoimmune chronic active hepatitis
    • Wen L, Peakman M, Lobo-Yeo A et al. T-cell directed hepatocyte damage in autoimmune chronic active hepatitis. Lancet 1990 : 336 : 1527 30.
    • (1990) Lancet , vol.336 , pp. 1527-30
    • Wen, L.1    Peakman, M.2    Lobo-Yeo, A.3
  • 21
    • 0025825932 scopus 로고
    • Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis
    • Lohr H, Manns M, Kyriatsoulis A et al. Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis. Clin Exp Immunol 1991 : 84 : 297 302.
    • (1991) Clin Exp Immunol , vol.84 , pp. 297-302
    • Lohr, H.1    Manns, M.2    Kyriatsoulis, A.3
  • 22
    • 0028221369 scopus 로고
    • Meyer zum Buschenfelde K-H. Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic active hepatitis of different etiology
    • Lohr HF, Schaak JF, Gergen G, Fleischer B, Dienes H-P, Meyer zum Buschenfelde K-H. Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic active hepatitis of different etiology. Liver 1994 : 14 : 161 6.
    • (1994) Liver , vol.14 , pp. 161-6
    • Lohr, H.F.1    Schaak, J.F.2    Gergen, G.3    Fleischer, B.4    Dienes, H.-P.5
  • 23
    • 0034051816 scopus 로고    scopus 로고
    • Increase in CD95 (Fas/APO-1)-positive CD4+ and CD8+ T cells in peripheral blood derived from patients with autoimmune hepatitis or chronic hepatitis C with autoimmune phenomena
    • Ogawa S, Sakaguchi K, Takaki A et al. Increase in CD95 (Fas/APO-1)-positive CD4+ and CD8+ T cells in peripheral blood derived from patients with autoimmune hepatitis or chronic hepatitis C with autoimmune phenomena. J Gastroenterol Hepatol 2000 : 15 : 69 75.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 69-75
    • Ogawa, S.1    Sakaguchi, K.2    Takaki, A.3
  • 24
    • 0028888832 scopus 로고
    • Characterisation of human Fas gene - Exon/intron organisation and promotor region
    • Cheng J, Liu C, Koopman WJ, Mountz JD. Characterisation of human Fas gene - exon/intron organisation and promotor region. J Immunol 1995 : 154 : 1239 45.
    • (1995) J Immunol , vol.154 , pp. 1239-45
    • Cheng, J.1    Liu, C.2    Koopman, W.J.3    Mountz, J.D.4
  • 25
    • 0031151509 scopus 로고    scopus 로고
    • Identification and characterisation of polymorphisms in the promoter region of human Apo-1/Fas (CD95) gene
    • Huang QR, Morris D, Manolios N. Identification and characterisation of polymorphisms in the promoter region of human Apo-1/Fas (CD95) gene. Mol Immunol 1997 : 34 : 577 82.
    • (1997) Mol Immunol , vol.34 , pp. 577-82
    • Huang, Q.R.1    Morris, D.2    Manolios, N.3
  • 26
    • 0032746823 scopus 로고    scopus 로고
    • Evaluation of a new apo-1/Fas promoter polymorphism in rheumatoid arthritis and systemic lupus erythematosus patients
    • Huang QR, Danis V, Lassere M, Edmonds J, Manolinos N. Evaluation of a new apo-1/Fas promoter polymorphism in rheumatoid arthritis and systemic lupus erythematosus patients. Rheumatology 1999 : 38 : 645 51.
    • (1999) Rheumatology , vol.38 , pp. 645-51
    • Huang, Q.R.1    Danis, V.2    Lassere, M.3    Edmonds, J.4    Manolinos, N.5
  • 27
    • 0034061220 scopus 로고    scopus 로고
    • Evaluation of the apo-1/Fas promoter mvaI polymorphism in multiple sclerosis
    • Huang QR, Teutsch SM, Buhler MM et al. Evaluation of the apo-1/Fas promoter mvaI polymorphism in multiple sclerosis. Mult Scler 2000 : 6 : 14 8.
    • (2000) Mult Scler , vol.6 , pp. 14-8
    • Huang, Q.R.1    Teutsch, S.M.2    Buhler, M.M.3
  • 28
    • 21344432363 scopus 로고    scopus 로고
    • Fas polymorphisms influence susceptibility to autoimmune hepatitis
    • Hiraide A, Imazeki F, Yokosuka O et al. Fas polymorphisms influence susceptibility to autoimmune hepatitis. Am J Gastroenterol 2005 : 100 : 1322 9.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1322-9
    • Hiraide, A.1    Imazeki, F.2    Yokosuka, O.3
  • 29
    • 25844485937 scopus 로고    scopus 로고
    • FASL-844C polymorphism is associated with increased activation-induced cell death and risk of cervical cancer
    • Sun T, Zhou Y, Li H et al. FASL-844C polymorphism is associated with increased activation-induced cell death and risk of cervical cancer. J Exp Med 2005 : 202 : 967 74.
    • (2005) J Exp Med , vol.202 , pp. 967-74
    • Sun, T.1    Zhou, Y.2    Li, H.3
  • 30
    • 0031926054 scopus 로고    scopus 로고
    • Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus
    • Mehrian R, Quismorio FP Jr., Strassmann G et al. Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus. Arthritis Rheum 1998 : 41 : 596 602.
    • (1998) Arthritis Rheum , vol.41 , pp. 596-602
    • Mehrian, R.1    Quismorio Jr., F.P.2    Strassmann, G.3
  • 31
    • 0032718310 scopus 로고    scopus 로고
    • International Autoimmune Hepatitis Group report: Review of criteria for diagnosis of autoimmune hepatitis
    • Alvarez F, Berg PA, Bianchi FB et al. International Autoimmune Hepatitis Group report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999 : 31 : 929 38.
    • (1999) J Hepatol , vol.31 , pp. 929-38
    • Alvarez, F.1    Berg, P.A.2    Bianchi, F.B.3
  • 32
    • 0026645855 scopus 로고
    • Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis
    • Czaja AJ, Manns MP, Homburger HA. Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis. Gastroenterology 1992 : 103 : 1290 5.
    • (1992) Gastroenterology , vol.103 , pp. 1290-5
    • Czaja, A.J.1    Manns, M.P.2    Homburger, H.A.3
  • 33
    • 0020525405 scopus 로고
    • Autoimmune features as determinants of prognosis in steroid-treated chronic active hepatitis of uncertain etiology
    • Czaja AJ, Davis GL, Ludwig J, Baggenstoss AH, Taswell HF. Autoimmune features as determinants of prognosis in steroid-treated chronic active hepatitis of uncertain etiology. Gastroenterology 1983 : 85 : 713 7.
    • (1983) Gastroenterology , vol.85 , pp. 713-7
    • Czaja, A.J.1    Davis, G.L.2    Ludwig, J.3    Baggenstoss, A.H.4    Taswell, H.F.5
  • 34
    • 0027682831 scopus 로고
    • Genetic predispositions for the immunological features of chronic active hepatitis
    • Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Genetic predispositions for the immunological features of chronic active hepatitis. Hepatology 1993 : 18 : 816 822.
    • (1993) Hepatology , vol.18 , pp. 816-822
    • Czaja, A.J.1    Carpenter, H.A.2    Santrach, P.J.3    Moore, S.B.4
  • 35
  • 36
    • 0031775104 scopus 로고    scopus 로고
    • Detection of antinuclear antibodies. Comparative evaluation of enzyme immunoassay and indirect immunofluorescence methods
    • Homburger HA, Cahen YD, Griffiths J, Jacob GL. Detection of antinuclear antibodies. Comparative evaluation of enzyme immunoassay and indirect immunofluorescence methods. Arch Pathol Lab Med 1998 : 122 : 993 9.
    • (1998) Arch Pathol Lab Med , vol.122 , pp. 993-9
    • Homburger, H.A.1    Cahen, Y.D.2    Griffiths, J.3    Jacob, G.L.4
  • 37
    • 0016802724 scopus 로고
    • Prednisone for chronic active liver disease: Dose titration, standard dose, and combination with azathioprine compared
    • Summerskill WHJ, Korman MG, Ammon HV, Baggenstoss AH. Prednisone for chronic active liver disease: dose titration, standard dose, and combination with azathioprine compared. Gut 1975 : 16 : 876 83.
    • (1975) Gut , vol.16 , pp. 876-83
    • Summerskill, W.H.J.1    Korman, M.G.2    Ammon, H.V.3    Baggenstoss, A.H.4
  • 38
    • 0027146326 scopus 로고
    • Sensitivity, specificity and predictability of biopsy interpretations in chronic hepatitis
    • Czaja AJ, Carpenter HA. Sensitivity, specificity and predictability of biopsy interpretations in chronic hepatitis. Gastroenterology 1993 : 105 : 1824 32.
    • (1993) Gastroenterology , vol.105 , pp. 1824-32
    • Czaja, A.J.1    Carpenter, H.A.2
  • 39
    • 2542572604 scopus 로고    scopus 로고
    • Progressive fibrosis during corticosteroid therapy of autoimmune hepatitis
    • Czaja AJ, Carpenter HA. Progressive fibrosis during corticosteroid therapy of autoimmune hepatitis. Hepatology 2004 : 39 : 1631 38.
    • (2004) Hepatology , vol.39 , pp. 1631-38
    • Czaja, A.J.1    Carpenter, H.A.2
  • 40
    • 0023242606 scopus 로고
    • Sustained remission following corticosteroid therapy of severe HBsAg-negative chronic active hepatitis
    • Czaja AJ, Beaver SJ, Shiels MT. Sustained remission following corticosteroid therapy of severe HBsAg-negative chronic active hepatitis. Gastroenterology 1987 : 92 : 215 9.
    • (1987) Gastroenterology , vol.92 , pp. 215-9
    • Czaja, A.J.1    Beaver, S.J.2    Shiels, M.T.3
  • 41
    • 0036211577 scopus 로고    scopus 로고
    • Sustained remission after corticosteroid therapy for type 1 autoimmune hepatitis: A retrospective analysis
    • Czaja AJ, Menon KVN, Carpenter HA. Sustained remission after corticosteroid therapy for type 1 autoimmune hepatitis: a retrospective analysis. Hepatology 2002 : 35 : 890 7.
    • (2002) Hepatology , vol.35 , pp. 890-7
    • Czaja, A.J.1    Menon, K.V.N.2    Carpenter, H.A.3
  • 42
    • 1642285767 scopus 로고    scopus 로고
    • Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis
    • Czaja AJ, Carpenter HA. Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis. J Hepatol 2004 : 40 : 644 50.
    • (2004) J Hepatol , vol.40 , pp. 644-50
    • Czaja, A.J.1    Carpenter, H.A.2
  • 44
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis- immune regulation in a dynamic and unpredicatble antigenic environment
    • Lenardo M, Chan FK, Hornung F et al. Mature T lymphocyte apoptosis- immune regulation in a dynamic and unpredicatble antigenic environment. Annu Rev Immunol 1999 : 17 : 221 53.
    • (1999) Annu Rev Immunol , vol.17 , pp. 221-53
    • Lenardo, M.1    Chan, F.K.2    Hornung, F.3
  • 45
    • 0034574306 scopus 로고    scopus 로고
    • The multifaceted role of Fas signalling in immune cell homeostasis and autoimmunity
    • Siegel RM, Chan FK-M, Chun HJ, Lenardo MJ. The multifaceted role of Fas signalling in immune cell homeostasis and autoimmunity. Nat Immunol 2000 : 1 : 469 75.
    • (2000) Nat Immunol , vol.1 , pp. 469-75
    • Siegel, R.M.1    Fk-M, C.2    Chun, H.J.3    Lenardo, M.J.4
  • 46
    • 0027291205 scopus 로고
    • Lethal effect of the anti-Fas antibody in mice
    • Ogasawara J, Watanabe-Fukunaga M, Adachi M et al. Lethal effect of the anti-Fas antibody in mice. Nature 1993 : 364 : 806 9.
    • (1993) Nature , vol.364 , pp. 806-9
    • Ogasawara, J.1    Watanabe-Fukunaga, M.2    Adachi, M.3
  • 47
    • 0032822999 scopus 로고    scopus 로고
    • Apoptosis and the liver: A mechanism of disease, growth regulation, and carcinogenesis
    • Patel T, Steer CJ, Gores GJ. Apoptosis and the liver: a mechanism of disease, growth regulation, and carcinogenesis. Hepatology 1999 : 30 : 811 5.
    • (1999) Hepatology , vol.30 , pp. 811-5
    • Patel, T.1    Steer, C.J.2    Gores, G.J.3
  • 48
    • 0034060334 scopus 로고    scopus 로고
    • Apoptosis and liver disease
    • Rust C, Gores GJ. Apoptosis and liver disease. Am J Med 2000 : 108 : 567 74.
    • (2000) Am J Med , vol.108 , pp. 567-74
    • Rust, C.1    Gores, G.J.2
  • 51
    • 0031002790 scopus 로고    scopus 로고
    • Essential roles of the Fas ligand in the development of hepatitis
    • Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S. Essential roles of the Fas ligand in the development of hepatitis. Nat Med 1997 : 3 : 409 13.
    • (1997) Nat Med , vol.3 , pp. 409-13
    • Kondo, T.1    Suda, T.2    Fukuyama, H.3    Adachi, M.4    Nagata, S.5
  • 52
    • 0036721727 scopus 로고    scopus 로고
    • Immunomodulatory effects of the liver: Deletion of activated CD4 effector cells and suppression of interferon-gamma producing cells after intravenous protein immunisation
    • Klugewitz K, Blumenthal-Barby F, Schrage A, Knolle PA, Hamann A, Crispe IN. Immunomodulatory effects of the liver: deletion of activated CD4 effector cells and suppression of interferon-gamma producing cells after intravenous protein immunisation. J Immunol 2002 : 169 : 2407 13.
    • (2002) J Immunol , vol.169 , pp. 2407-13
    • Klugewitz, K.1    Blumenthal-Barby, F.2    Schrage, A.3    Knolle, P.A.4    Hamann, A.5    Crispe, I.N.6
  • 53
    • 0036241848 scopus 로고    scopus 로고
    • Biology and significance of T cell apoptosis in the liver
    • Park S, Murray D, John B, Crispe IN. Biology and significance of T cell apoptosis in the liver. Immunol Cell Biol 2001 : 80 : 74 83.
    • (2001) Immunol Cell Biol , vol.80 , pp. 74-83
    • Park, S.1    Murray, D.2    John, B.3    Crispe, I.N.4
  • 54
    • 0035990250 scopus 로고    scopus 로고
    • A functional polymorphism in Fas (CD95/Apo-1) gene promoter associated with SLE
    • Kanemitsu S, Ihara K, Saifddin A et al. A functional polymorphism in Fas (CD95/Apo-1) gene promoter associated with SLE. J Rheumatol 2002 : 29 : 1183 8.
    • (2002) J Rheumatol , vol.29 , pp. 1183-8
    • Kanemitsu, S.1    Ihara, K.2    Saifddin, A.3
  • 55
    • 0032146551 scopus 로고    scopus 로고
    • Mechanisms of spontaneous resolution of rat liver fibrosis: Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
    • Iredale JP, Benyon RC, Pickering J et al. Mechanisms of spontaneous resolution of rat liver fibrosis: hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 1998 : 102 : 538 49.
    • (1998) J Clin Invest , vol.102 , pp. 538-49
    • Iredale, J.P.1    Benyon, R.C.2    Pickering, J.3
  • 56
    • 0035083958 scopus 로고    scopus 로고
    • Apoptosis of hepatic stellate cells: Involvement in resolution of biliary fibrosis and regulation by soluble growth factors
    • Issa R, Williams E, Trim N et al. Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors. Gut 2001 : 48 : 548 57.
    • (2001) Gut , vol.48 , pp. 548-57
    • Issa, R.1    Williams, E.2    Trim, N.3
  • 57
    • 0037192866 scopus 로고    scopus 로고
    • Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: Implications for reversibility of liver fibrosis
    • Murphy FR, Issa R, Zhou X et al. Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. J Biol Chem 2002 : 277 : 11069 76.
    • (2002) J Biol Chem , vol.277 , pp. 11069-76
    • Murphy, F.R.1    Issa, R.2    Zhou, X.3
  • 58
    • 0021749087 scopus 로고
    • Development and prognosis of histologic cirrhosis in corticosteroid- treated HBsAg-negative chronic active hepatitis
    • Davis GL, Czaja AJ, Ludwig J. Development and prognosis of histologic cirrhosis in corticosteroid-treated HBsAg-negative chronic active hepatitis. Gastroenterology 1984 : 87 : 1222 7.
    • (1984) Gastroenterology , vol.87 , pp. 1222-7
    • Davis, G.L.1    Czaja, A.J.2    Ludwig, J.3
  • 59
    • 0030065386 scopus 로고    scopus 로고
    • Prognosis of histological cirrhosis in type 1 autoimmune hepatitis
    • Roberts SK, Therneau T, Czaja AJ. Prognosis of histological cirrhosis in type 1 autoimmune hepatitis. Gastroenterology 1996 : 110 : 848 57.
    • (1996) Gastroenterology , vol.110 , pp. 848-57
    • Roberts, S.K.1    Therneau, T.2    Czaja, A.J.3
  • 60
    • 0014097538 scopus 로고
    • Chronic lymphadenopathy simulating malignant lymphoma
    • Canale VC, Smith CH. Chronic lymphadenopathy simulating malignant lymphoma. J Pediatr 1967 : 70 : 891 9.
    • (1967) J Pediatr , vol.70 , pp. 891-9
    • Canale, V.C.1    Smith, C.H.2
  • 61
    • 0033509379 scopus 로고    scopus 로고
    • The spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/Apo-1) mutations
    • Vaishnaw AK, Toubi E, Ohsako S et al. The spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/Apo-1) mutations. Arthritis Rheum 1999 : 42 : 1833 42.
    • (1999) Arthritis Rheum , vol.42 , pp. 1833-42
    • Vaishnaw, A.K.1    Toubi, E.2    Ohsako, S.3
  • 62
    • 0033361766 scopus 로고    scopus 로고
    • ALPS with a defective Fas genotype: Influence on penetrance
    • Jackson CE, Fischer RE, Hsu AP et al. ALPS with a defective Fas genotype: influence on penetrance. Am J Hum Genet 1999 : 64 : 1002 14.
    • (1999) Am J Hum Genet , vol.64 , pp. 1002-14
    • Jackson, C.E.1    Fischer, R.E.2    Hsu, A.P.3
  • 63
    • 0032917731 scopus 로고    scopus 로고
    • Autoantigens as substrates for apoptotic proteases: Implications for the pathogenesis of systemic autoimmune disease
    • Rosen A, Casicola-Rosen L. Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease. Cell Death Diff 1999 : 6 : 6 12.
    • (1999) Cell Death Diff , vol.6 , pp. 6-12
    • Rosen, A.1    Casicola-Rosen, L.2
  • 64
    • 0032704386 scopus 로고    scopus 로고
    • A Fas promoter polymorphism at position -670 in the enhancer region does not confer susceptibility to Felty's and large granular lymphocyte syndromes
    • Coakley G, Manolios N, Loughran TP Jr., Panayi GS, Lanchbury JS. A Fas promoter polymorphism at position -670 in the enhancer region does not confer susceptibility to Felty's and large granular lymphocyte syndromes. Rheumatology 1999 : 38 : 883 6.
    • (1999) Rheumatology , vol.38 , pp. 883-6
    • Coakley, G.1    Manolios, N.2    Loughran Jr., T.P.3    Panayi, G.S.4    Lanchbury, J.S.5
  • 65
    • 0034095610 scopus 로고    scopus 로고
    • Complete molecular scanning of the human Fas gene: Mutational analysis and linkage studies in families with type 1 diabetes mellitus
    • Nolsoe RL, Kristiansen OP, Sangthongpitag K et al. Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type 1 diabetes mellitus. Diabetologia 2000 : 43 : 800 8.
    • (2000) Diabetologia , vol.43 , pp. 800-8
    • Nolsoe, R.L.1    Kristiansen, O.P.2    Sangthongpitag, K.3


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