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Volumn 174, Issue , 2000, Pages 250-259

Genetic susceptibilities for immune expression and liver cell injury in autoimmune hepatitis

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; AUTOANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EPITOPE; HLA ANTIGEN; LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; POLYPEPTIDE;

EID: 0034077771     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0528.2002.017401.x     Document Type: Review
Times cited : (183)

References (102)
  • 1
    • 0021378462 scopus 로고
    • Natural history, clinical features, and treatment of autoimmune hepatitis
    • 1. Czaja AJ. Natural history, clinical features, and treatment of autoimmune hepatitis. Semin Liver Dis 1984;4:1-12.
    • (1984) Semin Liver Dis , vol.4 , pp. 1-12
    • Czaja, A.J.1
  • 2
    • 0027679646 scopus 로고
    • Meeting report. International Autoimmune Hepatitis Group
    • 2. Johnson PJ, et al. Meeting report. International Autoimmune Hepatitis Group. Hepatology 1993;18:998-1005.
    • (1993) Hepatology , vol.18 , pp. 998-1005
    • Johnson, P.J.1
  • 3
    • 0029757986 scopus 로고    scopus 로고
    • Diagnosis and therapy of autoimmune liver disease
    • 3. Czaja AJ. Diagnosis and therapy of autoimmune liver disease. Med Clin North Am 1996;80:973-994.
    • (1996) Med Clin North Am , vol.80 , pp. 973-994
    • Czaja, A.J.1
  • 4
    • 0031713987 scopus 로고    scopus 로고
    • Immunological liver diseases in children
    • 4. Mieli-Vergani G, Vergani D. Immunological liver diseases in children. Semin Liver Dis 1998;18:271-279.
    • (1998) Semin Liver Dis , vol.18 , pp. 271-279
    • Mieli-Vergani, G.1    Vergani, D.2
  • 5
    • 0029125292 scopus 로고
    • The validity and importance of subtypes of autoimmune hepatitis: A point of view
    • 5. Czaja AJ, Manns MP. The validity and importance of subtypes of autoimmune hepatitis: a point of view. Am J Gastroenterol 1995;90:1206-1211.
    • (1995) Am J Gastroenterol , vol.90 , pp. 1206-1211
    • Czaja, A.J.1    Manns, M.P.2
  • 6
    • 0023555290 scopus 로고
    • Chronic active hepatitis associated with antiliver/kidney microsome antibody type 1: A second type of "autoimmune" hepatitis
    • 6. Homberg J-C, et al. Chronic active hepatitis associated with antiliver/kidney microsome antibody type 1: a second type of "autoimmune" hepatitis. Hepatology 1987;7:1333-1339.
    • (1987) Hepatology , vol.7 , pp. 1333-1339
    • Homberg, J.-C.1
  • 7
    • 0026645855 scopus 로고
    • Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis
    • 7. Czaja AJ, Manns MP, Homburger HA. Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis. Gastroenterology 1992;103:1290-1295.
    • (1992) Gastroenterology , vol.103 , pp. 1290-1295
    • Czaja, A.J.1    Manns, M.P.2    Homburger, H.A.3
  • 8
    • 0001184307 scopus 로고
    • Autoimmune hepatitis: Current therapeutic concepts
    • 8. Czaja AJ. Autoimmune hepatitis: current therapeutic concepts. Clin Immunother 1994;1:413-429.
    • (1994) Clin Immunother , vol.1 , pp. 413-429
    • Czaja, A.J.1
  • 9
    • 0032892468 scopus 로고    scopus 로고
    • Drug therapy in the management of type I autoimmune hepatitis
    • 9. Czaja AJ. Drug therapy in the management of type I autoimmune hepatitis. Drugs 1999;57:49-68.
    • (1999) Drugs , vol.57 , pp. 49-68
    • Czaja, A.J.1
  • 10
    • 0021353811 scopus 로고
    • Identification of the hepatic asialo-glycoprotein receptor (hepatic lectin) as a component of liver specific membrane lipoprotein (LSP)
    • 10. McFarlane IG, McFarlane BM, Major GN, Tolley P, Williams R. Identification of the hepatic asialo-glycoprotein receptor (hepatic lectin) as a component of liver specific membrane lipoprotein (LSP). Clin Exp Immunol 1984;55:347-354.
    • (1984) Clin Exp Immunol , vol.55 , pp. 347-354
    • McFarlane, I.G.1    McFarlane, B.M.2    Major, G.N.3    Tolley, P.4    Williams, R.5
  • 11
    • 0026096131 scopus 로고
    • The asialoglycoprotein receptor as target structure in autoimmune liver diseases
    • 11. Poralla T, Treichel U, Lohr H, Fleischer B. The asialoglycoprotein receptor as target structure in autoimmune liver diseases. Semin Liver Dis 1991;11:215-222.
    • (1991) Semin Liver Dis , vol.11 , pp. 215-222
    • Poralla, T.1    Treichel, U.2    Lohr, H.3    Fleischer, B.4
  • 12
    • 0029738908 scopus 로고    scopus 로고
    • Frequency and significance of antibodies to asialoglycoprotein receptor in type 1 autoimmune hepatitis
    • 12. Czaja AJ, Pfeifer KD, Decker RH, Vallari AS. Frequency and significance of antibodies to asialoglycoprotein receptor in type 1 autoimmune hepatitis. Dig Dis Sci 1996;41:1733-1740.
    • (1996) Dig Dis Sci , vol.41 , pp. 1733-1740
    • Czaja, A.J.1    Pfeifer, K.D.2    Decker, R.H.3    Vallari, A.S.4
  • 13
    • 0024580945 scopus 로고
    • Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1
    • 13. Manns MP, Johnson EF, Griffin KJ, Tan EM, Sullivan KF. Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1. J Clin Invest 1989;83:1066-1072.
    • (1989) J Clin Invest , vol.83 , pp. 1066-1072
    • Manns, M.P.1    Johnson, E.F.2    Griffin, K.J.3    Tan, E.M.4    Sullivan, K.F.5
  • 14
    • 0025992973 scopus 로고
    • LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase
    • 14. Manns MP, Griffin KJ, Sullivan KF, Johnson EF. LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase. J Clin Invest 1991;88:1370-1378.
    • (1991) J Clin Invest , vol.88 , pp. 1370-1378
    • Manns, M.P.1    Griffin, K.J.2    Sullivan, K.F.3    Johnson, E.F.4
  • 15
    • 0027293444 scopus 로고
    • Characterization of the anti-liver-kidney microsome antibody (anti-LKM1) from hepatitis C virus-positive and -negative sera
    • 15. Yamamoto AM, Cresteil D, Homberg JC, Alvarez F. Characterization of the anti-liver-kidney microsome antibody (anti-LKM1) from hepatitis C virus-positive and -negative sera. Gastroenterology 1993;104:1762-1767.
    • (1993) Gastroenterology , vol.104 , pp. 1762-1767
    • Yamamoto, A.M.1    Cresteil, D.2    Homberg, J.C.3    Alvarez, F.4
  • 16
    • 0027388999 scopus 로고
    • Cytochromes P-450 in human hepatocyte plasma membrane: Recognition by several autoantibodies
    • 16. Loeper J, et al. Cytochromes P-450 in human hepatocyte plasma membrane: recognition by several autoantibodies. Gastroenterology 1993;104:203-216.
    • (1993) Gastroenterology , vol.104 , pp. 203-216
    • Loeper, J.1
  • 17
    • 0025303638 scopus 로고
    • Patients with type II autoimmune hepatitis express functionally intact cytochrome P-450 db1 that is inhibited by LKM-1 autoantibodies in vitro but not in vivo
    • 17. Manns M, et al. Patients with type II autoimmune hepatitis express functionally intact cytochrome P-450 db1 that is inhibited by LKM-1 autoantibodies in vitro but not in vivo. Hepatology 1990;12:127-132.
    • (1990) Hepatology , vol.12 , pp. 127-132
    • Manns, M.1
  • 18
    • 0025825932 scopus 로고
    • Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis
    • 18. Lohr H, et al. Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis. Clin Exp Immunol 1991;84:297-302.
    • (1991) Clin Exp Immunol , vol.84 , pp. 297-302
    • Lohr, H.1
  • 19
    • 0028890333 scopus 로고
    • Autoimmune hepatitis: Evolving concepts and treatment strategìes
    • 19. Czaja AJ. Autoimmune hepatitis: evolving concepts and treatment strategìes. Dig Dis Sci 1995;40:435-456.
    • (1995) Dig Dis Sci , vol.40 , pp. 435-456
    • Czaja, A.J.1
  • 21
    • 0033034609 scopus 로고    scopus 로고
    • Behavior and significance of autoantibodies in type 1 autoimmune hepatitis
    • 21. Czaja AJ. Behavior and significance of autoantibodies in type 1 autoimmune hepatitis. J Hepatol 1999;30:394-401.
    • (1999) J Hepatol , vol.30 , pp. 394-401
    • Czaja, A.J.1
  • 22
    • 0023751449 scopus 로고
    • The significance of natural autoantibodies
    • 22. Tomer Y, Shoenfeld Y. The significance of natural autoantibodies. Immunol Invest 1988;17:389-424.
    • (1988) Immunol Invest , vol.17 , pp. 389-424
    • Tomer, Y.1    Shoenfeld, Y.2
  • 23
    • 0026451666 scopus 로고
    • Altered major histocompatibility complex-restricted antigen recognition by T cells from elderly humans
    • 23. Schwab R, Russo C, Weksler ME. Altered major histocompatibility complex-restricted antigen recognition by T cells from elderly humans. Eur J Immunol 1992;22:2989-2993.
    • (1992) Eur J Immunol , vol.22 , pp. 2989-2993
    • Schwab, R.1    Russo, C.2    Weksler, M.E.3
  • 24
    • 0031757840 scopus 로고    scopus 로고
    • Immunological cross-reactivity to multiple autoantigens in patients with liver kidney microsomal type 1 autoimmune hepatitis
    • 24. Choudhuri K, Gregorio GV, Mieli-Vergani G, Vergani D. Immunological cross-reactivity to multiple autoantigens in patients with liver kidney microsomal type 1 autoimmune hepatitis. Hepatology 1998;28:1177-1181.
    • (1998) Hepatology , vol.28 , pp. 1177-1181
    • Choudhuri, K.1    Gregorio, G.V.2    Mieli-Vergani, G.3    Vergani, D.4
  • 25
    • 0029859871 scopus 로고    scopus 로고
    • Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases
    • 25. Lucey DR, Clerici M, Shearer GM. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev 1996;9:532-562.
    • (1996) Clin Microbiol Rev , vol.9 , pp. 532-562
    • Lucey, D.R.1    Clerici, M.2    Shearer, G.M.3
  • 27
    • 0015506324 scopus 로고
    • Association of autoimmune active chronic hepatitis with HL-A1, 8
    • 27. Mackay IR, Morris PJ. Association of autoimmune active chronic hepatitis with HL-A1, 8. Lancet 1972;2:793-795.
    • (1972) Lancet , vol.2 , pp. 793-795
    • Mackay, I.R.1    Morris, P.J.2
  • 28
    • 0016713325 scopus 로고
    • Genetic analysis of patients with chronic active hepatitis
    • 28. Page AR, Sharp HL, Greenberg LJ. Genetic analysis of patients with chronic active hepatitis. J Clin Invest 1975;56:530-535.
    • (1975) J Clin Invest , vol.56 , pp. 530-535
    • Page, A.R.1    Sharp, H.L.2    Greenberg, L.J.3
  • 29
    • 0018078606 scopus 로고
    • Increased frequency of HLA-DRW4 in chronic active hepatitis
    • 29. Williams RM, et al. Increased frequency of HLA-DRW4 in chronic active hepatitis. Vox Sang 1978;35:366-369.
    • (1978) Vox Sang , vol.35 , pp. 366-369
    • Williams, R.M.1
  • 30
    • 0019292069 scopus 로고
    • HLA associations with autoimmune-type chronic active hepatitis: Identification of B8-DRw3 haplotype by family studies
    • 30. Mackay IR, Tait BD. HLA associations with autoimmune-type chronic active hepatitis: identification of B8-DRw3 haplotype by family studies. Gastroenterology 1980;79:95-98.
    • (1980) Gastroenterology , vol.79 , pp. 95-98
    • Mackay, I.R.1    Tait, B.D.2
  • 32
    • 0025904366 scopus 로고
    • Susceptibility to autoimmune chronic active hepatitis: Human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors
    • 32. Donaldson PT, Doherty DG, Hayllar KM, McFarlane IG, Johnson PJ, Williams R. Susceptibility to autoimmune chronic active hepatitis: human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors. Hepatology 1991;13:701-706.
    • (1991) Hepatology , vol.13 , pp. 701-706
    • Donaldson, P.T.1    Doherty, D.G.2    Hayllar, K.M.3    McFarlane, I.G.4    Johnson, P.J.5    Williams, R.6
  • 33
    • 0027425574 scopus 로고
    • Human leukocyte antigen A1-B8-DR3-DQ2-DPB1 *0401 extended haplotype in autoimmune hepatitis
    • 33. Manabe K, et al. Human leukocyte antigen A1-B8-DR3-DQ2-DPB1 *0401 extended haplotype in autoimmune hepatitis. Hepatology 1993;18:1334-1337.
    • (1993) Hepatology , vol.18 , pp. 1334-1337
    • Manabe, K.1
  • 35
    • 0028091080 scopus 로고
    • Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis
    • 35. Doherty DG, et al. Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis. Hepatology 1994;19:609-615.
    • (1994) Hepatology , vol.19 , pp. 609-615
    • Doherty, D.G.1
  • 36
    • 0030962578 scopus 로고    scopus 로고
    • Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis
    • 36. Strettell MDJ, et al. Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis. Gastroenterology 1997;112:2028-2035.
    • (1997) Gastroenterology , vol.112 , pp. 2028-2035
    • Strettell, M.D.J.1
  • 38
    • 0000305564 scopus 로고    scopus 로고
    • Immunogenetics of liver disease
    • Bircher J, Benhamou J-P, McIntyre N, Rizetto M, Rodes J, eds. Oxford: Oxford University Press
    • 38. Donaldson PT, Manns MP. Immunogenetics of liver disease. In: Bircher J, Benhamou J-P, McIntyre N, Rizetto M, Rodes J, eds. Oxford textbook of clinical hepatology. Oxford: Oxford University Press; 1999. p. 173-188.
    • (1999) Oxford Textbook of Clinical Hepatology , pp. 173-188
    • Donaldson, P.T.1    Manns, M.P.2
  • 39
    • 0025611422 scopus 로고
    • Association of autoimmune hepatitis with HLA-Bw54 and DR4 in Japanese patients
    • 39. Seki T, Kiyosawa K, Inoko H, Ota M. Association of autoimmune hepatitis with HLA-Bw54 and DR4 in Japanese patients. Hepatology 1990;12:1300-1304.
    • (1990) Hepatology , vol.12 , pp. 1300-1304
    • Seki, T.1    Kiyosawa, K.2    Inoko, H.3    Ota, M.4
  • 40
    • 0026768377 scopus 로고
    • HLA class II molecules and autoimmune hepatitis susceptibility in Japanese patients
    • 40. Seki T, et al. HLA class II molecules and autoimmune hepatitis susceptibility in Japanese patients. Gastroenterology 1992;103:1041-1047.
    • (1992) Gastroenterology , vol.103 , pp. 1041-1047
    • Seki, T.1
  • 41
    • 0028125280 scopus 로고
    • Chronic active autoimmune hepatitis in children. Strong association with a particular HLA DR6 (DRBI*1301) haplotype
    • 41. Fainboim L, et al. Chronic active autoimmune hepatitis in children. Strong association with a particular HLA DR6 (DRBI*1301) haplotype. Hum Immunol 1994;41:146-150.
    • (1994) Hum Immunol , vol.41 , pp. 146-150
    • Fainboim, L.1
  • 42
    • 84989571822 scopus 로고
    • Two-locus involvement in the association of human leukocyte antigen with the extrahepatic manifestations of autoimmune chronic active hepatitis
    • 42. Marcos Y, et al. Two-locus involvement in the association of human leukocyte antigen with the extrahepatic manifestations of autoimmune chronic active hepatitis. Hepatology 1994;19:1371-1374.
    • (1994) Hepatology , vol.19 , pp. 1371-1374
    • Marcos, Y.1
  • 43
    • 0032092934 scopus 로고    scopus 로고
    • MHC class II sequences of susceptibility and protection in Mexicans with autoimmune hepatitis
    • 43. Vazquez-Garcia MN, et al. MHC class II sequences of susceptibility and protection in Mexicans with autoimmune hepatitis. J Hepatol 1998;28:985-990.
    • (1998) J Hepatol , vol.28 , pp. 985-990
    • Vazquez-Garcia, M.N.1
  • 45
    • 0032978099 scopus 로고    scopus 로고
    • Genetic heterogeneity in susceptibility to autoimmune hepatitis types 1 and 2
    • 45. Bittencourt PL, et al. Genetic heterogeneity in susceptibility to autoimmune hepatitis types 1 and 2. Am J Gastroenterol 1999;94:1906-1913.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1906-1913
    • Bittencourt, P.L.1
  • 46
    • 0031049137 scopus 로고    scopus 로고
    • Autoimmune hepatitis in childhood. A 20 year survey
    • 46. Gregorio GV, et al. Autoimmune hepatitis in childhood. A 20 year survey. Hepatology 1997;25:541-547.
    • (1997) Hepatology , vol.25 , pp. 541-547
    • Gregorio, G.V.1
  • 47
    • 0026643063 scopus 로고
    • Amino acid substitutions at position 38 of the DRβ polypeptide confer susceptibility to and protection from primary sclerosing cholangitis
    • 47. Farrant JM, et al. Amino acid substitutions at position 38 of the DRβ polypeptide confer susceptibility to and protection from primary sclerosing cholangitis. Hepatology 1992;16:390-395.
    • (1992) Hepatology , vol.16 , pp. 390-395
    • Farrant, J.M.1
  • 48
    • 0028920393 scopus 로고
    • HLA DR and DQ are not markers for rapid progression in primary sclerosing cholangitis
    • 48. Olerup O, Olsson R, Hultcrantz R, Broome U. HLA DR and DQ are not markers for rapid progression in primary sclerosing cholangitis. Gastroenterology 1995;108:870-878.
    • (1995) Gastroenterology , vol.108 , pp. 870-878
    • Olerup, O.1    Olsson, R.2    Hultcrantz, R.3    Broome, U.4
  • 50
    • 0031032711 scopus 로고    scopus 로고
    • Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis
    • 50. Czaja AJ, et al. Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis. Hepatology 1997;25:317-323.
    • (1997) Hepatology , vol.25 , pp. 317-323
    • Czaja, A.J.1
  • 51
    • 0025218099 scopus 로고
    • Clinical and prognostic implications of human leukocyte antigen B8 in corticosteroid-treated severe autoimmune chronic active hepatitis
    • 51. Czaja AJ, Rakela J, Hay JE, Moore SB. Clinical and prognostic implications of human leukocyte antigen B8 in corticosteroid-treated severe autoimmune chronic active hepatitis. Gastroenterology 1990;98:1587-1593.
    • (1990) Gastroenterology , vol.98 , pp. 1587-1593
    • Czaja, A.J.1    Rakela, J.2    Hay, J.E.3    Moore, S.B.4
  • 52
    • 0026571063 scopus 로고
    • Prognostic features and role of liver transplantation in severe corticosteroid-treated autoimmune chronic active hepatitis
    • 52. Sanchez-Urdazpal L, Czaja AJ, van Hoek B, Krom RAF, Wiesner RH. Prognostic features and role of liver transplantation in severe corticosteroid-treated autoimmune chronic active hepatitis. Hepatology 1992;15:215-221.
    • (1992) Hepatology , vol.15 , pp. 215-221
    • Sanchez-Urdazpal, L.1    Czaja, A.J.2    Van Hoek, B.3    Krom, R.A.F.4    Wiesner, R.H.5
  • 53
    • 0027682831 scopus 로고
    • Genetic predispositions for the immunological features of chronic active hepatitis
    • 53. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Genetic predispositions for the immunological features of chronic active hepatitis. Hepatology 1993;18:816-822.
    • (1993) Hepatology , vol.18 , pp. 816-822
    • Czaja, A.J.1    Carpenter, H.A.2    Santrach, P.J.3    Moore, S.B.4
  • 55
    • 0025131118 scopus 로고
    • A unified hypothesis for the complex genetics of HLA associations with IDDM
    • 55. Nepom GT. A unified hypothesis for the complex genetics of HLA associations with IDDM. Diabetes 1990;39:1153-1157.
    • (1990) Diabetes , vol.39 , pp. 1153-1157
    • Nepom, G.T.1
  • 56
    • 0026500805 scopus 로고
    • HLA and insulin-dependent diabetes: A protective perspective
    • 56. Sheehy MJ. HLA and insulin-dependent diabetes: a protective perspective. Diabetes 1992;41:123-129.
    • (1992) Diabetes , vol.41 , pp. 123-129
    • Sheehy, M.J.1
  • 57
    • 0027217789 scopus 로고
    • Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
    • 57. Brown JH, et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 1993;364:33-39.
    • (1993) Nature , vol.364 , pp. 33-39
    • Brown, J.H.1
  • 58
    • 0033519712 scopus 로고    scopus 로고
    • The new immunology - The end of immunosuppressive drug therapy?
    • 58. Schwartz RS. The new immunology - the end of immunosuppressive drug therapy? N Engl J Med 1999;340:1754-1756.
    • (1999) N Engl J Med , vol.340 , pp. 1754-1756
    • Schwartz, R.S.1
  • 59
    • 0025016823 scopus 로고
    • Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: Relevance to genetic predisposition to systemic lupus erythematosus
    • 59. Jacob CO, Fronek Z, Lewis GD, Koo M, Hansen JA, McDevitt HO. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci USA 1990;87:1233-1237.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1233-1237
    • Jacob, C.O.1    Fronek, Z.2    Lewis, G.D.3    Koo, M.4    Hansen, J.A.5    McDevitt, H.O.6
  • 60
    • 0027397580 scopus 로고
    • Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: A possible link to insulin-dependent diabetes mellitus
    • 60. Pociot F, et al. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 1993;23:224-231.
    • (1993) Eur J Immunol , vol.23 , pp. 224-231
    • Pociot, F.1
  • 61
    • 0031091743 scopus 로고    scopus 로고
    • Is CTLA-4 a master switch for peripheral T cell tolerance?
    • 61. Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J Immunol 1997;158:1989-1993.
    • (1997) J Immunol , vol.158 , pp. 1989-1993
    • Bluestone, J.A.1
  • 62
    • 0030694234 scopus 로고    scopus 로고
    • The emerging role of CTLA-4 as an immune attenuator
    • 62. Thompson CB, Allison JP. The emerging role of CTLA-4 as an immune attenuator. Immunity 1997;7:445-450.
    • (1997) Immunity , vol.7 , pp. 445-450
    • Thompson, C.B.1    Allison, J.P.2
  • 64
    • 0032902704 scopus 로고    scopus 로고
    • The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases
    • 64. Price P, et al. The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases. Immunol Rev 1999;167:257-274.
    • (1999) Immunol Rev , vol.167 , pp. 257-274
    • Price, P.1
  • 65
    • 0026691627 scopus 로고
    • Serum levels of cytokines in chronic liver diseases
    • 65. Tilg H, et al. Serum levels of cytokines in chronic liver diseases. Gastroenterology 1992;103:264-274.
    • (1992) Gastroenterology , vol.103 , pp. 264-274
    • Tilg, H.1
  • 66
    • 0028819043 scopus 로고
    • Circulating levels of interleukin-6, interleukin-8, and tumor necrosis factor-α in children with autoimmune hepatitis
    • 66. Maggiore G, De Benedetti F, Massa M, Pignatti P, Martini A. Circulating levels of interleukin-6, interleukin-8, and tumor necrosis factor-α in children with autoimmune hepatitis. J Pediatr Gastroenterol Nutr 1995;20:23-27.
    • (1995) J Pediatr Gastroenterol Nutr , vol.20 , pp. 23-27
    • Maggiore, G.1    De Benedetti, F.2    Massa, M.3    Pignatti, P.4    Martini, A.5
  • 67
    • 0027422349 scopus 로고
    • Cytokine profile of viral and autoimmune chronic active hepatitis
    • 67. Al-Wabel A, Al-Janadi M, Raziuddin S. Cytokine profile of viral and autoimmune chronic active hepatitis. J Allergy Clin Immunol 1993;92:902-908.
    • (1993) J Allergy Clin Immunol , vol.92 , pp. 902-908
    • Al-Wabel, A.1    Al-Janadi, M.2    Raziuddin, S.3
  • 68
    • 0028221369 scopus 로고
    • Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology
    • 68. Lohr HF, Schaak JF, Gerken G, Fleischer B, Dienes H-P, Meyer zum Buschenfelde K-H. Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology. Liver 1994;14:161-166.
    • (1994) Liver , vol.14 , pp. 161-166
    • Lohr, H.F.1    Schaak, J.F.2    Gerken, G.3    Fleischer, B.4    Dienes, H.-P.5    Meyer Zum Buschenfelde, K.-H.6
  • 69
    • 0027379721 scopus 로고
    • Analysis of the in vitro cytokine production by liver-infiltrating T cells of patients with autoimmune hepatitis
    • 69. Schlaak JF, Lohr H, Gallati H, Meyer zum Buschenfelde K-H, Fleischer B. Analysis of the in vitro cytokine production by liver-infiltrating T cells of patients with autoimmune hepatitis. Clin Exp Immunol 1993;94:168-173.
    • (1993) Clin Exp Immunol , vol.94 , pp. 168-173
    • Schlaak, J.F.1    Lohr, H.2    Gallati, H.3    Meyer Zum Buschenfelde, K.-H.4    Fleischer, B.5
  • 70
  • 71
    • 0029859871 scopus 로고    scopus 로고
    • Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases
    • 71. Lucey DR, Clerici M, Shearer GM. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev 1996;9:532-562.
    • (1996) Clin Microbiol Rev , vol.9 , pp. 532-562
    • Lucey, D.R.1    Clerici, M.2    Shearer, G.M.3
  • 72
    • 0029925880 scopus 로고    scopus 로고
    • Actions of cylokines on the immune response and viral interactions: An overview
    • 72. Peters M. Actions of cylokines on the immune response and viral interactions: an overview. Hepatology 1996;23:909-916.
    • (1996) Hepatology , vol.23 , pp. 909-916
    • Peters, M.1
  • 73
    • 4243236698 scopus 로고    scopus 로고
    • Nature and behavior of immunoregulatory cytokines in type 1 autoimmune hepatitis
    • 73. Czaja AJ, Sievers C, Zein NN. Nature and behavior of immunoregulatory cytokines in type 1 autoimmune hepatitis. Gastroenterology 1999;116:A1199.
    • (1999) Gastroenterology , vol.116
    • Czaja, A.J.1    Sievers, C.2    Zein, N.N.3
  • 74
    • 0025775935 scopus 로고
    • Lymphokines and the immune response: The central role of interleukin-2
    • 74. Swain SL. Lymphokines and the immune response: the central role of interleukin-2. Curr Opin Immunol 1991;3:304-310.
    • (1991) Curr Opin Immunol , vol.3 , pp. 304-310
    • Swain, S.L.1
  • 75
    • 0022399321 scopus 로고
    • Immune mechanisms in autoimmune chronic active hepatitis
    • 75. Vento S, Nouri-Aria KT, Eddleston ALWF. Immune mechanisms in autoimmune chronic active hepatitis. Scand J Gastroenterol 1985;20 (Suppl 114):91-103.
    • (1985) Scand J Gastroenterol , vol.20 , Issue.SUPPL. 114 , pp. 91-103
    • Vento, S.1    Nouri-Aria, K.T.2    Eddleston, A.L.W.F.3
  • 76
    • 0032862558 scopus 로고    scopus 로고
    • Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis
    • 76. Cookson S, et al. Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis. Hepatology 1999;30:851-856.
    • (1999) Hepatology , vol.30 , pp. 851-856
    • Cookson, S.1
  • 77
    • 0032819862 scopus 로고    scopus 로고
    • Cytokine polymorphisms associated with clinical features and treatment outcome in type 1 autoimmune hepatitis
    • 77. Czaja AJ, Cookson S, Constantini PK, Clare M, Underhill JA, Donaldson PT. Cytokine polymorphisms associated with clinical features and treatment outcome in type 1 autoimmune hepatitis. Gastroenterology 1999;177:645-652.
    • (1999) Gastroenterology , vol.177 , pp. 645-652
    • Czaja, A.J.1    Cookson, S.2    Constantini, P.K.3    Clare, M.4    Underhill, J.A.5    Donaldson, P.T.6
  • 78
    • 0002857444 scopus 로고
    • Effects of a tumor necrosis factor (TNF-α) promoter base transition on transcriptional activity
    • 78. Wilson AG, Symons JA, McDowell TL, di Giovine FS, Duff GW. Effects of a tumor necrosis factor (TNF-α) promoter base transition on transcriptional activity. Br J Rheumatol 1994;33:89-92.
    • (1994) Br J Rheumatol , vol.33 , pp. 89-92
    • Wilson, A.G.1    Symons, J.A.2    McDowell, T.L.3    Di Giovine, F.S.4    Duff, G.W.5
  • 79
    • 0027534914 scopus 로고
    • An allelic polymorphism within the human tumor necrosis factor α promoter region is strongly associtaed with HLA A1, B8, and DR3 alleles
    • 79. Wilson AG, de Vries N, Pociot F, di Giovine FS, van der Putte LB, Duff GW. An allelic polymorphism within the human tumor necrosis factor α promoter region is strongly associtaed with HLA A1, B8, and DR3 alleles. J Exp Med 1993;177:557-560.
    • (1993) J Exp Med , vol.177 , pp. 557-560
    • Wilson, A.G.1    De Vries, N.2    Pociot, F.3    Di Giovine, F.S.4    Van Der Putte, L.B.5    Duff, G.W.6
  • 80
    • 0027397580 scopus 로고
    • Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: A possible link to insulin-dependent diabetes mellitus
    • 80. Pociot F, et al. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 1993;23:224-231.
    • (1993) Eur J Immunol , vol.23 , pp. 224-231
    • Pociot, F.1
  • 81
    • 0031091743 scopus 로고    scopus 로고
    • Is CTLA-4 a master switch for peripheral T cell tolerance?
    • 81. Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J Immunol 1997;158:1989-1993.
    • (1997) J Immunol , vol.158 , pp. 1989-1993
    • Bluestone, J.A.1
  • 82
    • 0030694234 scopus 로고    scopus 로고
    • The emerging role of CTLA-4 as an immune attenuator
    • 82. Thompson CB, Allison JP. The emerging role of CTLA-4 as an immune attenuator. Immunity 1997;7:445-450.
    • (1997) Immunity , vol.7 , pp. 445-450
    • Thompson, C.B.1    Allison, J.P.2
  • 83
    • 8544274482 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA-4 polymorphisms in multiple ethnic groups
    • 83. Marron MP, et al. Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA-4 polymorphisms in multiple ethnic groups. Hum Mol Gen 1997;6:1275-1282.
    • (1997) Hum Mol Gen , vol.6 , pp. 1275-1282
    • Marron, M.P.1
  • 84
    • 4243236522 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphism confers susceptibility to type 1 autoimmune hepatitis
    • 84. Agarwal K, Czaja AJ, Jones DEJ, Donaldson PT. CTLA-4 gene polymorphism confers susceptibility to type 1 autoimmune hepatitis. Hepatology 1999;30:495A.
    • (1999) Hepatology , vol.30
    • Agarwal, K.1    Czaja, A.J.2    Jones, D.E.J.3    Donaldson, P.T.4
  • 85
    • 4243775725 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis
    • 85. Agarwal K, et al. CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis. Hepatology 1998;28:404A.
    • (1998) Hepatology , vol.28
    • Agarwal, K.1
  • 86
    • 0003332806 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphism associated with primary sclerosing cholangitis (PSC)
    • 86. Saarinen A, Broome U, Liger A, Olsson R, Hulcrantz R, Olerup O. CTLA-4 gene polymorphism associated with primary sclerosing cholangitis (PSC). J Hepatol 1998;28 (Suppl):124.
    • (1998) J Hepatol , vol.28 , Issue.SUPPL. , pp. 124
    • Saarinen, A.1    Broome, U.2    Liger, A.3    Olsson, R.4    Hulcrantz, R.5    Olerup, O.6
  • 87
    • 0031014716 scopus 로고    scopus 로고
    • CTLA-4 alanine-17 confers genetic susceptiblity to Graves' Disease and to type 1 diabetes mellitus
    • 87. Donner H, et al. CTLA-4 alanine-17 confers genetic susceptiblity to Graves' Disease and to type 1 diabetes mellitus. J Clin Endocrinol Metab 1997;81:143-146.
    • (1997) J Clin Endocrinol Metab , vol.81 , pp. 143-146
    • Donner, H.1
  • 88
    • 8944259914 scopus 로고    scopus 로고
    • The CTLA-4 region of chromosome 2q33 is linked to, and associated with, type 1 diabetes
    • 88. Nistico L, et al. The CTLA-4 region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum Mol Gen 1996;5:1075-1080.
    • (1996) Hum Mol Gen , vol.5 , pp. 1075-1080
    • Nistico, L.1
  • 89
    • 0028226929 scopus 로고
    • T-cell receptor constant β germline polymorphisms and susceptibility to autoimmune hepatitis
    • 89. Manabe K, et al. T-cell receptor constant β germline polymorphisms and susceptibility to autoimmune hepatitis. Gastroenterology 1994;106:1321-1325.
    • (1994) Gastroenterology , vol.106 , pp. 1321-1325
    • Manabe, K.1
  • 90
    • 0031888390 scopus 로고    scopus 로고
    • Limited T cell receptor Vβ-chain repertoire of liver-infiltrating T cells in autoimmune hepatitis
    • 90. Arenz M, Meyer zum Buschenfelde K-H, Lohr HF. Limited T cell receptor Vβ-chain repertoire of liver-infiltrating T cells in autoimmune hepatitis. J Hepatol 1998;28:70-77.
    • (1998) J Hepatol , vol.28 , pp. 70-77
    • Arenz, M.1    Meyer Zum Buschenfelde, K.-H.2    Lohr, H.F.3
  • 92
    • 0023575854 scopus 로고
    • Immunogenetic studies of autoimmune chronic active hepatitis: HLA, immunoglobulin allotypes and autoantibodies
    • 92. Krawitt EL, et al. Immunogenetic studies of autoimmune chronic active hepatitis: HLA, immunoglobulin allotypes and autoantibodies. Hepatology 1987;7:1305-1310.
    • (1987) Hepatology , vol.7 , pp. 1305-1310
    • Krawitt, E.L.1
  • 93
  • 94
    • 0028822075 scopus 로고
    • Significance of human leukocyte antigens DR3 and DR4 in chronic viral hepatitis
    • 94. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Significance of human leukocyte antigens DR3 and DR4 in chronic viral hepatitis. Dig Dis Sci 1995;40:2098-2106.
    • (1995) Dig Dis Sci , vol.40 , pp. 2098-2106
    • Czaja, A.J.1    Carpenter, H.A.2    Santrach, P.J.3    Moore, S.B.4
  • 95
    • 0030757975 scopus 로고    scopus 로고
    • Histological findings in chronic hepatitis C with autoimmune features
    • 95. Czaja AJ, Carpenter HA. Histological findings in chronic hepatitis C with autoimmune features. Hepatology 1997;26:459-466.
    • (1997) Hepatology , vol.26 , pp. 459-466
    • Czaja, A.J.1    Carpenter, H.A.2
  • 96
    • 0030069520 scopus 로고    scopus 로고
    • Genetic predispositions for immunological features in chronic liver diseases other than autoimmune hepatitis
    • 96. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Genetic predispositions for immunological features in chronic liver diseases other than autoimmune hepatitis. J Hepatol 1996;24:52-59.
    • (1996) J Hepatol , vol.24 , pp. 52-59
    • Czaja, A.J.1    Carpenter, H.A.2    Santrach, P.J.3    Moore, S.B.4
  • 97
    • 0027214036 scopus 로고
    • Evidence against hepatitis viruses as important causes of severe autoimmune hepatitis in the United States
    • 97. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB, Taswell HF, Homburger HA. Evidence against hepatitis viruses as important causes of severe autoimmune hepatitis in the United States. J Hepatol 1993;18:342-352.
    • (1993) J Hepatol , vol.18 , pp. 342-352
    • Czaja, A.J.1    Carpenter, H.A.2    Santrach, P.J.3    Moore, S.B.4    Taswell, H.F.5    Homburger, H.A.6
  • 98
    • 0029917789 scopus 로고    scopus 로고
    • Validation of a scoring system for the diagnosis of autoimmune hepatitis
    • 98. Czaja AJ, Carpenter HA. Validation of a scoring system for the diagnosis of autoimmune hepatitis. Dig Dis Sci 1996;41:305-314.
    • (1996) Dig Dis Sci , vol.41 , pp. 305-314
    • Czaja, A.J.1    Carpenter, H.A.2
  • 99
    • 0028059240 scopus 로고
    • Autoimmune hepatitis and viral infection
    • 99. Czaja AJ. Autoimmune hepatitis and viral infection. Gastroenterol Clin North Am 1994;23:547-566.
    • (1994) Gastroenterol Clin North Am , vol.23 , pp. 547-566
    • Czaja, A.J.1
  • 100
    • 0027146326 scopus 로고
    • Sensitivity, specificity and predictability of biopsy interpretations in chronic hepatitis
    • 100. Czaja AJ, Carpenter HA. Sensitivity, specificity and predictability of biopsy interpretations in chronic hepatitis. Gastroenterology 1993;105:1824-1832.
    • (1993) Gastroenterology , vol.105 , pp. 1824-1832
    • Czaja, A.J.1    Carpenter, H.A.2
  • 101
    • 0030268388 scopus 로고    scopus 로고
    • The variant forms of autoimmune hepatitis
    • 101. Czaja AJ. The variant forms of autoimmune hepatitis. Ann Intern Med 1996;125:588-598.
    • (1996) Ann Intern Med , vol.125 , pp. 588-598
    • Czaja, A.J.1
  • 102
    • 0031948143 scopus 로고    scopus 로고
    • Frequency and nature of the variant syndromes of autoimmune liver disease
    • 102. Czaja AJ. Frequency and nature of the variant syndromes of autoimmune liver disease. Hepatology 1998;28:360-365.
    • (1998) Hepatology , vol.28 , pp. 360-365
    • Czaja, A.J.1


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