Effects of a new low dose soy protein β-sitosterol association on plasma lipid levels and oxidation

European Journal of Nutrition

Volumn 43, Issue 5, 2004, Pages 319-322

  Cicero, Arrigo F G ^a   Minardi, Monica ^a   Mirembe, Sifa ^a   Pedro, Egidio ^a   Gaddi, Antonio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

sitosterol; Hypercholesterolemia; Phytosterols; Soy bean protein

Indexed keywords

HYPOCHOLESTEROLEMIC AGENT; SITOSTEROL; SOYBEAN PROTEIN;

ADULT; AGED; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONCENTRATION RESPONSE; DIET SUPPLEMENTATION; DIETARY INTAKE; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; FEMALE; FIBRINOGEN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HABIT; HUMAN; LIPID BLOOD LEVEL; MALE; OXIDATION; PROTEIN INTAKE; STATISTICAL SIGNIFICANCE; URIC ACID BLOOD LEVEL;

ANTICHOLESTEREMIC AGENTS; BODY WEIGHT; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOOD HABITS; HUMANS; HYPERCHOLESTEROLEMIA; LIPID PEROXIDATION; MALE; MIDDLE AGED; SITOSTEROLS; SOYBEAN PROTEINS; TREATMENT OUTCOME; TRIGLYCERIDES;

GLYCINE MAX; PHASEOLUS (ANGIOSPERM);

EID: 5644257080     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-004-0478-y     Document Type: Article

References (15)

1. Erdman JW Jr (2000) AHA Science Advisory: soy protein and cardiovascular disease: a statement for healthcare professionals from the Nutrition Committee of the AHA. Circulation 102(20): 2555-2559
2. Jones PJ, Raeini-Sarjaz M (2000) Plant sterols and their derivatives: the current spread of results. Nutr Rev 59(1):21-24
3. Anderson JW, Johnstone BM, Cook-Newell ME (1995) Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med 333:276-282
4. Becker M, Staab D, von Bergmann K (1993) Treatment of severe familial hyper-cholesterolemia in childhood with sitosterol and sitostanol. J Pediatr 122:292-296
5. Hallikainen MA, Sarkkinen ES, Gylling H, Erkkila AT, Uusitupa MI (2000) Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on a low-fat diet. Eur J Clin Nutr 54(9):715-725
6. Cicero AFG, Fiorito A, Panourgia MP, Sangiorgi Z, Gaddi A (2002) Effects of a new soy/β-sitosterol supplement on plasma lipids in moderately hypercholesterolemic subjects. J Am Diet Ass 102(12):1807-1811
7. Gaddi A, Cicero AFG, Dormi A, Pasquarelli V, S. D'Addato S (2001) The realisation of a project aimed at reducing the plasmatic lipid level in a large Italian rural population improves the mean calcium daily intake: the Brisighella Study. Eur J Clin Nutr 55(2): 97-106
8. Kraus RM, Eckel RH, Howerd B, Appel LJ, Danies SR, Deckelbaum EJ, Erdman JWJr et al. (2000) AHA Dietary Guidelines: revision 2000. A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation 102(18): 2284-2299
9. Cicero AFG, Braiato A, D'Addato S, Sangiorgi Z, Gaddi A (2000) A suggestion for Familial Hypercholesterolemia (FH) heterozygosity clinical diagnosis based on an epidemiological observation in a large Italian population. Int J Cardiol 74:5-11
10. Hattori Y, Suzuki M, Tsushima M, Yoshida M, Tokunaga Y, Wang Y, Zhao D, Takeuchi M, Hara Y, Ryomoto KI, Ikebuchi M, Kishioka H, Mannami T, Baba S, Harano Y (1998) Development of approximate formula for LDL-chol, LDL-apo B and LDL-chol/LDL-apo B as indices of hyperapobetalipoproteinemia and small dense LDL. Atherosclerosis 138(2):289-299
11. Ghiselli G, Gaddi A, Barozzi G, Ciarrocchi A, Descovich G (1992) Plasma lipoprotein(a) concentrations in familial hypercholesterolemic patients without coronary heart disease. Metabolism 41:833-838
12. Tatzber F, Esterbauer H (1995) Autoantibodies to oxidized low density lipoprotein. In: Bellomo G, Finardi G, Maggi E, Rice-Evance C (eds) Free Radicals, Lipoprotein Oxidation and Atherosclerosis. London, UK: Richelieu Press, pp 245-262
13. Blair SN, Capuzzi DM, Gottlieb SO, Nguyen T, Morgan JM, Cater NB (2000) Incremental reduction of serum total cholesterol and low-density lipoprotein cholesterol with the addition of plant stanol ester-containing spread to statin therapy. Am J Cardiol 86(1):46-52
14. Cicero AFG, Panourgia MP, Fiorito A, Linarello S, D'Addato S, Gaddi A (2002) Palatability and acceptability of a low dose soy protein/β- sitosterol association as cholesterol lowering agent. In: Kostner GE, Kostner KM (eds) Atherosclerosis: Risk factors, Diagnosis and Treatment. Monduzzi -Editore, Bologna, Italy, pp 567-570
15. Teede HJ, Dalais FS, Kotsopoulos D, Liang YL, Davis S, McGrath BP (2001) Dietary soy has both beneficial and potentially adverse cardiovascular effects: a placebo-controlled study in men and postmenopausal women. J Clin Endocr Metab 86(7):3053-3060