Characterization of the proteasome accessory factor (paf) operon in Mycobacterium tuberculosis

Journal of Bacteriology

Volumn 189, Issue 8, 2007, Pages 3044-3050

  Festa, Richard A ^a   Pearce, Michael J ^a   Darwin, K Heran ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANONITROGEN DERIVATIVE; PROTEASOME; PROTEASOME ACCESSORY FACTOR A; PROTEASOME ACCESSORY FACTOR B; PROTEASOME ACCESSORY FACTOR C; REACTIVE NITROGEN INTERMEDIATE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIUM MUTANT; GENE INSERTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OPERON; PAFA GENE; PAFB GENE; PAFC GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; STEADY STATE; TRANSPOSON;

BACTERIAL PROTEINS; CARRIER PROTEINS; DRUG RESISTANCE, BACTERIAL; GENES, BACTERIAL; MYCOBACTERIUM TUBERCULOSIS; OPERON; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN SUBUNITS; REACTIVE NITROGEN SPECIES; SUBSTRATE SPECIFICITY; VIRULENCE;

MYCOBACTERIUM TUBERCULOSIS;

EID: 34247866459     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01597-06     Document Type: Article

References (37)

1. Baumeister, W., J. Walz, F. Zühl, and E. Seemüller. 1998. The proteasome: paradigm of a self-compartmentalizing protease. Cell 92:367-380.
2. Berks, B. C., T. Palmer, and F. Sargent. 2005. Protein targeting by the bacterial twin-arginine translocation (Tat) pathway. Curr. Opin. Microbiol. 8:174-181.
3. Chong, S., and G. A. Garcia. 1994. A versatile and general prokaryotic expression vector, pLACT7. BioTechniques 17:686, 688, 690-691.
4. Chu-Ping, M., J. H. Vu, R. J. Proske, C. A. Slaughter, and G. N. DeMartino. 1994. Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome. J. Biol. Chem. 269:3539-3547.
5. Cole, S. T., K. Eiglmeier, J. Parkhill, K. D. James, N. R. Thomson, P. R. Wheeler, N. Honoré, T. Garnier, C. Churcher, D. Harris, K. Mungall, D. Basham, D. Brown, T. Chillingworth, R. Conner, R. M. Davies, K. Devlin, K. Duthoy, T. Feltwell, A. Fraser, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, C. Lacroix, J. Mclean, S. Moule, L. Murphy, K. Oliver, M. A. Quail, M.-A. Rajandream, K. M. Rutherford, S. Rutter, K. Seeger, S. Simon, M. Simmonds, J. Skelton, R. Squares, S. Squares, K. Stevens, K. Taylor, S. Whitehead, J. R. Woodward, and B. G. Barrell. 2001. Massive gene decay in the leprosy bacillus. Science 409:1007-1011.
6. Darwin, K. H., S. Ehrt, N. Weich, J.-C. Gutierrez-Ramos, and C. F. Nathan. 2003. The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide. Science 302:1963-1966.
7. Darwin, K. H., G. Lin, Z. Chen, H. Li, and C. Nathan. 2005. Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue. Mol. Microbiol. 55:561-571.
8. Datsenko, K. A., and B. L. Wanner. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97:6640-6645.
9. DeMartino, G. N., C. R. Moomaw, O. P. Zagnitko, R. J. Proske, M. Chu-Ping, S. J. Afendis, J. C. Swaffield, and C. A. Slaughter. 1994. PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family. J. Biol. Chem. 269:20878-20884.
10. De Mot, R., I. Nagy, J. Walz, and W. Baumeister. 1999. Proteasomes and other self-compartmentalizing proteases in prokaryotes. Trends Microbiol. 7:88-92.
11. Dye, C., S. Scheele, P. Dolin, V. Pathania, M. C. Raviglione, et al. 1999. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. JAMA. 282:677-686.
12. Ewann, F., M. Jackson, K. Pethe, A. Cooper, N. Mielcarek, D. Ensergueix, B. Gicquel, C. Locht, and P. Supply. 2002. Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis. Infect. Immun. 70:2256-2263.
13. Gottesman, S. 2003. Proteolysis in bacterial regulatory circuits. Annu. Rev. Cell Dev. Biol. 19:565-587.
14. Harlow, E., and D. P. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
15. Hu, G., G. Lin, M. Wang, L. Dick, R.-M. Xu, C. Nathan, and H. Li. 2006. Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate. Mol. Microbiol. 59:1417-1428.
16. Karimova, G., A. Ullmann, and D. Ladant. 2000. A bacterial two-hybrid system that exploits a cAMP signaling cascade in Escherichia coli. Methods Enzymol. 328:59-73.
17. Lane, J. M., and E. J. Rubin. 2006. Scaling down: a PCR-based method to efficiently screen for desired knockouts in a high density Mycobacterium tuberculosis picked mutant library. Tuberculosis 86:310-313.
18. Lin, G., G. Hu, C. Tsu, Y. Z. Kunes, H. Li, L. Dick, T. Parsons, P. Li, Z. Chen, P. Zwickl, N. Weich, and C. Nathan. 2006. Mycobacterium tuberculosis prcBA genes encode a gated proteasome. Mol. Microbiol. 59:1405-1416.
19. MacMicking, J. D., R. J. North, R. LaCourse, J. S. Mudgett, S. K. Shah, and C. F. Nathan. 1997. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl. Acad. Sci. USA 94:5243-5248.
20. McDonough, J. A., K. E. Hacker, A. R. Flores, M. S. Pavelka, Jr., and M. Braunstein. 2005. The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases. J. Bacteriol. 187:7667-7679.
21. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
22. Nagy, I., S. Geert, J. Vanderleyden, and R. De Mot. 1997. Further sequence analysis of the DNA regions with the Rhodococcus 20S proteasome structural genes reveals extensive homolgy with Mycobacterium leprae. DNA Seq. 7:225-228.
23. Nathan, C. F., and M. U. Shiloh. 2000. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc. Natl. Acad. Sci. USA 97:8841-8848.
24. Pearce, M. J., P. Arora, R. A. Festa, S. M. Butler-Wu, R. S. Gokhale, and K. H. Darwin. 2006. Identification of substrates of the Mycobacterium tuberculosis proteasome. EMBO J. 25:5423-5432.
25. Pickart, C. M., and R. E. Cohen. 2004. Proteasomes and their kin: proteases in the machine age. Nat. Rev. Mol. Cell. Biol. 5:177-187.
26. Russell, D. R. 2001. Mycobacterium tuberculosis: here today, and here tomorrow. Nat. Rev. 2:1-9.
27. Saint-Joanis, B., C. Demangel, M. Jackson, P. Brodin, L. Marsollier, H. Boshoff, and S. T. Cole. 2006. Inactivation of Rv2525c, a substrate of the twin-arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence. J. Bacteriol. 188:6669-6679.
28. Sambrook, J., T. Maniatis, and E. Fritsch. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
29. Sassetti, C. M., D. H. Boyd, and E. J. Rubin. 2001. Comprehensive identification of conditionally essential genes in mycobacteria. Proc. Natl. Acad. Sci. USA 98:12712-12717.
30. Shiloh, M. U., and C. F. Nathan. 2000. Reactive nitrogen intermediates and the pathogenesis of Salmonella and mycobacteria. Curr. Opin. Microbiol. 3:35-42.
31. Stover, C. K., V. F. de la Cruz, T. R. Fuerst, J. E. Burlein, L. A. Benson, L. T. Bennett, G. P. Bansal, J. F. Young, M. H. Lee, G. F. Hatfull, et al. 1991. New use of BCG for recombinant vaccines. Nature 351:456-460.
32. Tian, J., R. Bryk, M. Itoh, M. Suematsu, and C. Nathan. 2005. Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase. Proc. Natl. Acad. Sci. USA 102:10670-10675.
33. Vissa, V. D., and P. J. Brennan. 2001. The genome of Mycobacterium leprae: a minimal mycobacterial gene set. Genome Biol. 2:REVIEWS1023.
34. Voges, D., P. Zwickl, and W. Baumeister. 1999. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu. Rev. Biochem. 68:1015-1068.
35. Williams, D. L., M. Torrero, P. R. Wheeler, R. W. Truman, M. Yoder, N. Morrison, W. R. Bishai, and T. P. Gillis. 2004. Biological implications of Mycobacterium leprae gene expression during infection. J. Mol. Microbiol. Biotechnol. 8:58-72.
36. Zahrt, T. C., and V. Deretic. 2002. Reactive nitrogen and oxygen intermediates and bacterial defenses: unusual adaptations in Mycobacterium tuberculosis. Antioxid. Redox Signal. 4:141-159.
37. Zhou, Y., and S. Gottesman. 1998. Regulation of proteolysis of the stationary-phase sigma factor RpoS. J. Bacteriol. 180:1154-1158.