Role of PKA in the anti-Thy-1 antibody-induced neurite outgrowth of dorsal root ganglionic neurons

Journal of Cellular Biochemistry

Volumn 101, Issue 3, 2007, Pages 566-575

  Chen, Chien Hsing ^a   Chen, Yi Jen ^a   Jeng, Chung Jiuan ^b   Yang, Shih Hung ^a,c   Tung, Po Yuan ^a   Wang, Seu Mei ^a,d  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d NONE   (Taiwan)

Author keywords

Anti Thy 1 antibody; CREB; DRG neuron; MEK; Neurite outgrowth; PKA; Thy 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; FEMALE; MALE; NERVE FIBER GROWTH; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SPINAL GANGLION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CELL ADHESION MOLECULES; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; FEMALE; FLAVONOIDS; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; ISOANTIBODIES; MALE; MICROFILAMENT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEURITES; NEURONS; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 34247863760     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21217     Document Type: Article

References (55)

1. Ahn S, Olive M, Aggarwal S, Krylov D, Ginty DD, Vinson C. 1998. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Mol Cell Biol 18:967-977.
2. Avalos AM, Labra CV, Questa AFG, Leyton L. 2002. Signaling triggered by Thy-1 interaction with beta(3) integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function. Biol Res 35:231-238.
3. Avalos AM, Arthur WT, Schneider P, Quest AFG, Burridge K, Leyton L. 2004. Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. J Biol Chem 279: 39139-39145.
4. Batistatou A, Volonte C, Greene LA. 1992. Nerve growth factor employs multiple pathways to induce primary response genes in PC12 cells. Mol Biol Cell 3:363-371.
5. Bonni A, Ginty DD, Dudek H, GreenbergME. 1995. Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. Mol Cell Neurosci 6:168-183.
6. Charles MP, Adamski D, Kholler B, Pelletier L, Berger F, Wion D. 2003. Induction of neurite outgrowth in PC12 cells by the bacterial nucleoside N6-methyldeoxyadenosine is mediated through adenosine A2a receptors and via cAMP and MAPK signaling pathways. Biochem Biophys Res Commun 304:795-800.
7. Chen CH, Wang SM, Yang SH, Jeng CJ. 2005. Role of Thy-1 in in vivo and in vitro neural development and regeneration of dorsal root ganglionic neurons. J Cell Biochem 94:684-694.
8. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH. 1993. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855-859.
9. Curtis J, Finkbeiner S. 1999. Sending signals from the synapse to the nucleus: Possible roles for CaMK, Ras/ ERK, and SAPK pathways in the regulation of synaptic plasticity and neuronal growth. J Neurosci Res 58:88-95.
10. Deininger SO, Rajendran L, Lottspeich F, Przybylski M, Illges H, Stuermer CA, Reuter A. 2003a. Identification of teleost Thy-1 and association with the microdomain/lipid raft reggie proteins in regenerating CNS axons. Mol Cell Neurosci 22:544-554.
11. Deininger SO, Rajendran L, Lottspeich F, Przybylski M, Illges H, Stuermer CAO, Reuter A. 2003b. Identification of teleost Thy-1 and association with the microdornain/ lipid raft reggie proteins in regenerating CNS axons. Mol Cell Neurosci 22:544-554.
12. Doherty P, Singh A, Rimon G, Bolsover SR, Walsh FS. 1993. Thy-1 antibody-triggered neurite outgrowth requires an influx of calcium into neurons via N-type and L-type calcium Channels. J Cell Biol 122:181-189.
13. Ginty DD, Bonni A, Greenberg ME. 1994. Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 77:713-725.
14. Henke RC, Seeto GS, Jeffrey PL. 1997. Thy-1 and AvGp50 signal transduction complex in the avian nervous system: c-Fyn and G alpha i protein association and activation of signalling pathways. J Neurosci Res 49:655-670.
15. Jeng CJ, McCarroll SA, Martin TF, Floor E, Adams J, Krantz D, Butz S, Edwards R, Schweitzer ES. 1998. Thy-1 is a component common to multiple populations of synaptic vesicles. J Cell Biol 140:685-698.
16. Jessen U, Novitskaya V, Pedersen N, Serup P, Berezin V, Bock E. 2001. The transcription factors CREB and c-Fos play key roles in NCAM-mediated neuritogenesis in PC12-E2 cells. J Neurochem 79:1149-1160.
17. Kaplan DR, Miller FD. 2000. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10:381-391.
18. Kita Y, Kimura KD, Kobayashi M, Ihara S, Kaibuchi K, Kuroda S, Ui M, Iba H, Konishi H, Kikkawa U, Nagata S, Fukui Y. 1998. Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway. J Cell Sci 111(Pt 7):907-915.
19. Kocsis JD, Rand MN, Lankford KL, Waxman SG. 1994. Intracellular calcium mobilization and neurite outgrowth in mammalian neurons. J Neurobiol 25:252-264.
20. Kolkova K, Novitskaya V, Pedersen N, Berezin V, Bock E. 2000. Neural cell adhesion molecule-stimulated neurite outgrowth depends on activation of protein kinase C and the Ras-mitogen-activated protein kinase pathway. J Neurosci 20:2238-2246.
21. Kramer EM, Klein C, Koch T, Boytinck M, Trotter J. 1999. Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination. J Biol Chem 274:29042-29049.
22. Kroczek RA, Gunter KC, Germain RN, Shevach EM. 1986a. Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature 322:181-184.
23. Kroczek RA, Gunter KC, Seligmann B, Shevach EM. 1986b. Induction of T cell activation by monoclonal anti-Thy-1 antibodies. J Immunol 136:4379-4384.
24. Lang DM, Lommel S, Jung M, Ankerhold R, Petrausch B, Laessing U, Wiechers MF, Plattner H, Stuermer CAO. 1998. Identification of reggie-1 and reggie-2 as plasmamembrane-associated proteins which cocluster with activated GPI-anchored cell adhesion molecules in non-caveolar micropatches in neurons. J Neurobiol 37:502-523.
25. Ledbetter JA, June CH, Grosmaire LS, Rabinovitch PS. 1987. Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes. Proc Natl Acad Sci USA 84:1384-1388.
26. Lee SJ, Campomanes CR, Sikat PT, Greenfield AT, Allen PB, McEwen BS. 2004. Estrogen induces phosphorylation of cyclic AMP response element binding (pCREB) in primary hippocampal cells in a time-dependent manner. Neuroscience 124:549-560.
27. Leifer D, Lipton SA, Barnstable CJ, Masland RH. 1984. Monoclonal antibody to Thy-1 enhances regeneration of processes by rat retinal ganglion cells in culture. Science 224:303-306.
28. Leyton L, Schneider P, Labra CV, Ruegg C, Hetz CA, Quest AFG, Bron C. 2001. Thy-1 binds to integrin beta(3) on astrocytes and triggers formation of focal contact sites. Curr Biol 11:1028-1038.
29. Lipton SA, Leifer D, Barnstable CJ. 1992. Selectivity of Thy-1 monoclonal-antibodies in enhancing neurite outgrowth. Neurosci Lett 137:75-77.
30. Liu RY, Snider WD. 2001. Different signaling pathways mediate regenerative versus developmental sensory axon growth. J Neurosci 21:RC164.
31. Lonze BE, Ginty DD. 2002. Function and regulation of CREB family transcription factors in the nervous system. Neuron 35:605-623.
32. Lonze BE, Riccio A, Cohen S, Ginty DD. 2002a. Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron 34:371-385.
33. Lonze BE, Riccio A, Cohen S, Ginty DD. 2002b. Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron 34:371-385.
34. Ma W, Zheng WH, Powell K, Jhamandas K, Quirion R. 2001. Chronic morphine exposure increases the phosphorylation of MAP kinases and the transcription factor CREB in dorsal root ganglion neurons: An in vitro and in vivo study. Eur J Neurosci 14:1091-1104.
35. Mahanthappa NK, Patterson PH. 1992. Thy-1 involvement in neurite outgrowth - Perturbation by antibodies, phospholipase-C, and mutation. Dev Biol 150:47-59.
36. McIlvain HB, Baudy A, Sullivan K, Liu D, Pong K, Fennell M, Dunlop J. 2006. Pituitary adenylate cyclase-activating peptide (PACAP) induces differentiation in the neuronal F11 cell line through a PKA-dependent pathway. Brain Res 1077:16-23.
37. Nagase H, Yamakuni T, Matsuzaki K, Maruyama Y, Kasahara J, Hinohara Y, Kondo S, Mimaki Y, Sashida Y, Tank AW, Fukunaga K, Ohizumi Y. 2005. Mechanism of neurotrophic action of nobiletin in PC12D cells. Biochemistry 44:13683-13691.
38. Park SY, Lee JY, Choi JY, Park MJ, Kim DS. 2006. Nerve growth factor activates brain-derived neurotrophic factor promoter IV via extracellular signal-regulated protein kinase 1/2 in PC12 cells. Mol Cells 21:237-243.
39. 2+-stimulated adenylyl cyclases in LTP and memory formation. Int J Dev Neurosci 19:387-394.
40. Profirovic J, Gorovoy M, Niu J, Pavlovic S, Voyno-Yasenetskaya T. 2005. A novel mechanism of G protein-dependent phosphorylation of vasodilator- stimulated phosphoprotein. J Biol Chem 280:32866-32876.
41. Qiu J, Cafferty WB, McMahon SB, Thompson SW. 2005. Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation. J Neurosci 25:1645-1653.
42. Redmond L, Kashani A, Ghosh A. 2002. Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription. Neuron 34:999-1010.
43. Schmid RS, Graff RD, Schaller MD, Chen SZ, Schachner M, Hemperly JJ, Maness PF. 1999. NCAM stimulates the Ras-MAPK pathway and CREB phosphorylation in neuronal cells. J Neurobiol 38:542-558.
44. Seki M, Nawa H, Morioka T, Fukuchi T, Oite T, Abe H, Takei N. 2002. Establishment of a novel enzyme-linked immunosorbent assay for Thy-1; quantitative assessment of neuronal degeneration. Neurosci Lett 329:185-188.
45. Sivasahkaran R, Pei J, Wang KC, Zhang YP, Shields CB, Xu XM, He Z. 2004. PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration. Nat Neurosci 7:261-268.
46. Stuermer CA, Lang DM, Kirsch F, Wiechers M, Deininger SO, Plattner H. 2001. Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2. Mol Biol Cell 12:3031-3045.
47. Stuermer CAO, Plattner H. 2005. The 'lipid raft' microdomain proteins reggie-1 and reggie-2 (flotilliris) are scaffolds for protein interaction and signaling. Biochem Soc Symp 72:109-118.
48. Teng FY, Tang BL. 2006. Axonal regeneration in adult CNS neurons - Signaling molecules and pathways. J Neurochem 96:1501-1508.
49. Thomas PM, Samelson LE. 1992. The glycophosphatidylinositol-anchored Thy-1 molecule interacts with the P60fyn protein tyrosine kinase in T-cells. J Biol Chem 267:12317-12322.
50. Tiveron MC, Barboni E, Rivero FBP, Gormley AM, Seeley PJ, Grosveld F, Morris R. 1992. Selective-inhibition of neurite outgrowth on mature astrocytes by Thy-1 glycoprotein. Nature 355:745-748.
51. Tiveron MC, Nosten-Bertrand M, Jani H, Garnett D, Hirst EM, Grosveld F, Morris RJ. 1994. The mode of anchorage to the cell surface determines both the function and the membrane location of Thy-1 glycoprotein. J Cell Sci 107-1783-1796.
52. Tojima T, Ito E. 2004. Signal transduction cascades underlying de novo protein synthesis required for neuronal morphogenesis in differentiating neurons. Prog Neurobiol 72:183-193.
53. Tojima T, Kobayashi S, Ito E. 2003. Dual role of cyclic AMP-dependent protein kinase in neuritogenesis and synaptogenesis during neuronal differentiation. J Neurosci Res 74:829-837.
54. Vogt Weisenhorn DM, Roback LJ, Kwon JH, Wainer BH. 2001. Coupling of cAMP/PKA and MAPK signaling in neuronal cells is dependent on developmental stage. Exp Neurol 169:44-55.
55. Xue GP, Rivero BP, Morris RJ. 1991. The surface glycoprotein Thy-1 is excluded from growing axons during development: A study of the expression of Thy-1 during axogenesis in hippocampus and hindbrain. Development 112:161-176.