Structure-editing of nucleic acids for selective targeting of RNA

Current Topics in Medicinal Chemistry

Volumn 7, Issue 7, 2007, Pages 715-726

  Kumar, Vaijayanti A ^a   Ganesh, K N ^b  

^a NATIONAL CHEMICAL LABORATORY   (India)

^b INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

Author keywords

Antisense agent; Enantio DNA sequences; N type sugar ring; Oligonucleotides; Phosphoramidates

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; COMPLEMENTARY RNA; HEXITOL NUCLEIC ACID; NUCLEIC ACID; NUCLEOTIDE DERIVATIVE; OXETANOCIN; OXETANOCIN A; PEPTIDE NUCLEIC ACID; PHOSPHORAMIDIC ACID DERIVATIVE; RNA; THREOFURANOSYL NUCLEIC ACID OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ANTISENSE THERAPY; BINDING AFFINITY; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; DNA BINDING; DNA SEQUENCE; DNA STRAND; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HYDROGEN BOND; MOLECULAR DYNAMICS; NUCLEIC ACID BASE SUBSTITUTION; NUCLEIC ACID STRUCTURE; NUCLEIC ACID SYNTHESIS; PROTEIN BINDING; REVIEW; RNA BINDING; RNA SEQUENCE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

AMINES; ANIMALS; BIOMIMETIC MATERIALS; HUMANS; NUCLEIC ACID CONFORMATION; NUCLEIC ACIDS; PHOSPHORUS; RNA; STEREOISOMERISM; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS;

EID: 34247634635     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802607780487722     Document Type: Review

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