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Volumn 69, Issue 1, 2007, Pages 90-94

Anti-inflammatory effect is an important property of niacin on atherosclerosis beyond its lipid-altering effects

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ANTILIPEMIC AGENT; LIPID; LIPOPROTEIN; NICOTINIC ACID;

EID: 34247634533     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.11.026     Document Type: Article
Times cited : (22)

References (39)
  • 2
    • 1542780828 scopus 로고    scopus 로고
    • Niacin, lipids, and heart disease
    • Malik S., and Kashyap M.L. Niacin, lipids, and heart disease. Curr Cardiol Rep 5 (2003) 470-476
    • (2003) Curr Cardiol Rep , vol.5 , pp. 470-476
    • Malik, S.1    Kashyap, M.L.2
  • 3
    • 21544467275 scopus 로고    scopus 로고
    • Pathophysiology of coronary artery disease
    • Libby P., and Theroux P. Pathophysiology of coronary artery disease. Circulation 111 (2005) 3481-3488
    • (2005) Circulation , vol.111 , pp. 3481-3488
    • Libby, P.1    Theroux, P.2
  • 4
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - an inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. New Engl J Med 340 (1999) 115-126
    • (1999) New Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 5
    • 0036035527 scopus 로고    scopus 로고
    • Inflammatory bio-markers and cardiovascular risk prediction
    • Blake G.J., and Ridker P.M. Inflammatory bio-markers and cardiovascular risk prediction. J Int Med 252 (2002) 283-294
    • (2002) J Int Med , vol.252 , pp. 283-294
    • Blake, G.J.1    Ridker, P.M.2
  • 6
    • 0033751381 scopus 로고    scopus 로고
    • Mechanism of action of niacin on lipoprotein metabolism
    • Kamanna V.S., and Kashyap M.L. Mechanism of action of niacin on lipoprotein metabolism. Curr Atheroscler Rep 2 (2000) 36-46
    • (2000) Curr Atheroscler Rep , vol.2 , pp. 36-46
    • Kamanna, V.S.1    Kashyap, M.L.2
  • 7
    • 0033586641 scopus 로고    scopus 로고
    • Evidence for a new pathophysiological mechanism for coronary artery disease regression: hepatic lipase-mediated changes in LDL density
    • Zambon A., Hokanson J.E., Brown B.G., and Brunzell J.D. Evidence for a new pathophysiological mechanism for coronary artery disease regression: hepatic lipase-mediated changes in LDL density. Circulation 99 (1999) 1959-1964
    • (1999) Circulation , vol.99 , pp. 1959-1964
    • Zambon, A.1    Hokanson, J.E.2    Brown, B.G.3    Brunzell, J.D.4
  • 8
    • 0026724433 scopus 로고
    • Differential effects of nicotinic acid in subjects with different LDL subclass patterns
    • Superko H.R., and Krauss R.M. Differential effects of nicotinic acid in subjects with different LDL subclass patterns. Atherosclerosis 95 (1992) 69-76
    • (1992) Atherosclerosis , vol.95 , pp. 69-76
    • Superko, H.R.1    Krauss, R.M.2
  • 9
    • 0035423283 scopus 로고    scopus 로고
    • Effect of niacin and atorvastatin on lipoprotein subclasses in patients with atherogenic dyslipidemia
    • McKenney J.M., McCormick L.S., Schaefer E.J., Black D.M., and Watkins M.L. Effect of niacin and atorvastatin on lipoprotein subclasses in patients with atherogenic dyslipidemia. Am J Cardiol 88 (2001) 270-274
    • (2001) Am J Cardiol , vol.88 , pp. 270-274
    • McKenney, J.M.1    McCormick, L.S.2    Schaefer, E.J.3    Black, D.M.4    Watkins, M.L.5
  • 10
    • 0037099259 scopus 로고    scopus 로고
    • Relations of lipoprotein subclass levels and low-density lipoprotein size to progression of coronary artery disease in the Pravastatin Limitation of Atherosclerosis in the Coronary Arteries (PLAC-I) trial
    • Rosenson R.S., Otvos J.D., and Freedman D.S. Relations of lipoprotein subclass levels and low-density lipoprotein size to progression of coronary artery disease in the Pravastatin Limitation of Atherosclerosis in the Coronary Arteries (PLAC-I) trial. Am J Cardiol 90 (2002) 89-94
    • (2002) Am J Cardiol , vol.90 , pp. 89-94
    • Rosenson, R.S.1    Otvos, J.D.2    Freedman, D.S.3
  • 11
    • 0033551386 scopus 로고    scopus 로고
    • Epidemiology of hypertriglyceridemia and cardiovascular disease
    • Austin M.A. Epidemiology of hypertriglyceridemia and cardiovascular disease. Am J Cardiol 83 (1999) 13F-16F
    • (1999) Am J Cardiol , vol.83
    • Austin, M.A.1
  • 12
    • 0032951101 scopus 로고    scopus 로고
    • Niacin accelerates intracellular ApoB degradation by inhibiting triacylglycerol synthesis in human hepatoblastoma (HepG2) cells
    • Jin F.Y., Kamanna V.S., and Kashyap M.L. Niacin accelerates intracellular ApoB degradation by inhibiting triacylglycerol synthesis in human hepatoblastoma (HepG2) cells. Arterioscler Thromb Vasc Biol 19 (1999) 1051-1059
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1051-1059
    • Jin, F.Y.1    Kamanna, V.S.2    Kashyap, M.L.3
  • 13
    • 0035569951 scopus 로고    scopus 로고
    • Niacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterol
    • Sakai T., Kamanna V.S., and Kashyap M.L. Niacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterol. Arterioscler Thromb Vasc Biol 21 (2001) 1783-1789
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1783-1789
    • Sakai, T.1    Kamanna, V.S.2    Kashyap, M.L.3
  • 14
    • 0036606905 scopus 로고    scopus 로고
    • Comparison of extended-release niacin and atorvastatin monotherapies and combination treatment of the atherogenic lipid profile in diabetes mellitus
    • Van J.T., Pan J., Wasty T., Chan E., Wu X., and Charles M.A. Comparison of extended-release niacin and atorvastatin monotherapies and combination treatment of the atherogenic lipid profile in diabetes mellitus. Am J Cardiol 89 (2002) 1306-1308
    • (2002) Am J Cardiol , vol.89 , pp. 1306-1308
    • Van, J.T.1    Pan, J.2    Wasty, T.3    Chan, E.4    Wu, X.5    Charles, M.A.6
  • 15
    • 0025848995 scopus 로고
    • Altered particle size distribution of apolipoprotein A-I-containing lipoproteins in subjects with coronary artery disease
    • Cheung M.C., Brown B.G., Wolf A.C., and Albers J.J. Altered particle size distribution of apolipoprotein A-I-containing lipoproteins in subjects with coronary artery disease. J Lipid Res 32 (1991) 383-394
    • (1991) J Lipid Res , vol.32 , pp. 383-394
    • Cheung, M.C.1    Brown, B.G.2    Wolf, A.C.3    Albers, J.J.4
  • 16
    • 0024466520 scopus 로고
    • Pronounced lowering of serum levels of lipoprotein Lp(a) in hyperlipidaemic subjects treated with nicotinic acid
    • Carlson L.A., Hamsten A., and Asplund A. Pronounced lowering of serum levels of lipoprotein Lp(a) in hyperlipidaemic subjects treated with nicotinic acid. J Int Med 226 (1989) 271-276
    • (1989) J Int Med , vol.226 , pp. 271-276
    • Carlson, L.A.1    Hamsten, A.2    Asplund, A.3
  • 17
    • 0031409345 scopus 로고    scopus 로고
    • Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study
    • Berg K., Dahlén G., Christophersen B., Cook T., Kjekshus J., and Pedersen T. Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study. Clin Genet 52 (1997) 254-261
    • (1997) Clin Genet , vol.52 , pp. 254-261
    • Berg, K.1    Dahlén, G.2    Christophersen, B.3    Cook, T.4    Kjekshus, J.5    Pedersen, T.6
  • 18
    • 0003293442 scopus 로고    scopus 로고
    • Molecular identification of high and low affinity receptors for nicotinic acid
    • Wise A., Foord S.M., Fraser N.J., et al. Molecular identification of high and low affinity receptors for nicotinic acid. J Biol Chem 278 (2003) 9869-9874
    • (2003) J Biol Chem , vol.278 , pp. 9869-9874
    • Wise, A.1    Foord, S.M.2    Fraser, N.J.3
  • 19
    • 0037470749 scopus 로고    scopus 로고
    • Molecular identification of nicotinic acid receptor
    • Soga T., Kamohara M., Takasaki J., et al. Molecular identification of nicotinic acid receptor. Biochem Biophys Res Commun 303 (2003) 364-369
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 364-369
    • Soga, T.1    Kamohara, M.2    Takasaki, J.3
  • 20
    • 0037352280 scopus 로고    scopus 로고
    • PUMA-G and HM74 are receptors for nicotinic acid and mediate its antilipolytic effect
    • Tunaru S., Kero J., Schaub A., et al. PUMA-G and HM74 are receptors for nicotinic acid and mediate its antilipolytic effect. Nat Med 9 (2003) 352-355
    • (2003) Nat Med , vol.9 , pp. 352-355
    • Tunaru, S.1    Kero, J.2    Schaub, A.3
  • 21
    • 31044441839 scopus 로고    scopus 로고
    • Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid
    • Pike N.B. Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid. J Clin Invest 115 (2005) 3400-3403
    • (2005) J Clin Invest , vol.115 , pp. 3400-3403
    • Pike, N.B.1
  • 22
    • 22144459031 scopus 로고    scopus 로고
    • Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A
    • Zhang Y., Schmidt R.J., Foxworthy P., et al. Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A. Biochem Biophys Res Commun 334 (2005) 729-732
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 729-732
    • Zhang, Y.1    Schmidt, R.J.2    Foxworthy, P.3
  • 23
    • 0027200040 scopus 로고
    • Substrate delivery as a determinant of hepatic apoB secretion
    • Sniderman A.D., and Cianflone K. Substrate delivery as a determinant of hepatic apoB secretion. Arterioscler Thromb 13 (1993) 629-636
    • (1993) Arterioscler Thromb , vol.13 , pp. 629-636
    • Sniderman, A.D.1    Cianflone, K.2
  • 24
    • 0030798890 scopus 로고    scopus 로고
    • Fatty acid regulation of very low density lipoprotein production
    • Lewis G.F. Fatty acid regulation of very low density lipoprotein production. Curr Opin Lipidol 8 (1997) 146-153
    • (1997) Curr Opin Lipidol , vol.8 , pp. 146-153
    • Lewis, G.F.1
  • 25
    • 33745501028 scopus 로고    scopus 로고
    • The nicotinic acid receptor GPR109A (HM74A or PUMA-G) as a new therapeutic target
    • Offermanns S. The nicotinic acid receptor GPR109A (HM74A or PUMA-G) as a new therapeutic target. Trends Pharmacol Sci 27 (2006) 384-390
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 384-390
    • Offermanns, S.1
  • 27
    • 31044448925 scopus 로고    scopus 로고
    • GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing
    • Benyo Z., Gille A., Kero J., et al. GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. J Clin Invest 115 (2005) 3634-3640
    • (2005) J Clin Invest , vol.115 , pp. 3634-3640
    • Benyo, Z.1    Gille, A.2    Kero, J.3
  • 28
    • 0035666867 scopus 로고    scopus 로고
    • PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily
    • Schaub A., Futterer A., and Pfeffer K. PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily. Eur J Immunol 31 (2001) 3714-3725
    • (2001) Eur J Immunol , vol.31 , pp. 3714-3725
    • Schaub, A.1    Futterer, A.2    Pfeffer, K.3
  • 29
    • 10044284098 scopus 로고    scopus 로고
    • Effect of niacin on nitric oxide synthase expression in rat lung exposed to silica
    • Du H.K., Wang S.X., Liu Y., and Zhang S.W. Effect of niacin on nitric oxide synthase expression in rat lung exposed to silica. Zhonghua Yu Fang Yi Xue Za Zhi 38 (2004) 186-189
    • (2004) Zhonghua Yu Fang Yi Xue Za Zhi , vol.38 , pp. 186-189
    • Du, H.K.1    Wang, S.X.2    Liu, Y.3    Zhang, S.W.4
  • 30
    • 1542673224 scopus 로고    scopus 로고
    • The combined treatment with taurine and niacin blocks the bleomycin-induced activation of nuclear factor-kappaB and lung fibrosis
    • Giri S.N. The combined treatment with taurine and niacin blocks the bleomycin-induced activation of nuclear factor-kappaB and lung fibrosis. Adv Exp Med Biol 526 (2003) 381-394
    • (2003) Adv Exp Med Biol , vol.526 , pp. 381-394
    • Giri, S.N.1
  • 31
    • 0037232298 scopus 로고    scopus 로고
    • Nicotinamide is a potent inhibitor of proinflammatory cytokines
    • Ungerstedt J.S., Blomback M., and Soderstrom T. Nicotinamide is a potent inhibitor of proinflammatory cytokines. Clin Exp Immunol 131 (2003) 48-52
    • (2003) Clin Exp Immunol , vol.131 , pp. 48-52
    • Ungerstedt, J.S.1    Blomback, M.2    Soderstrom, T.3
  • 32
    • 0036035527 scopus 로고    scopus 로고
    • Inflammatory bio-markers and cardiovascular risk prediction
    • Blake G.J., and Ridker P.M. Inflammatory bio-markers and cardiovascular risk prediction. J Int Med 252 (2002) 283-294
    • (2002) J Int Med , vol.252 , pp. 283-294
    • Blake, G.J.1    Ridker, P.M.2
  • 33
    • 0037086184 scopus 로고    scopus 로고
    • Long-term safety and efficacy of a once-daily niacin/lovastatin formulation in patients with dyslipidemia
    • Kashyap M.L., McGovern M.E., Berra K., et al. Long-term safety and efficacy of a once-daily niacin/lovastatin formulation in patients with dyslipidemia. Am J Cardiol 89 (2002) 672-678
    • (2002) Am J Cardiol , vol.89 , pp. 672-678
    • Kashyap, M.L.1    McGovern, M.E.2    Berra, K.3
  • 34
    • 0037158150 scopus 로고    scopus 로고
    • Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of Niaspan trial
    • Grundy S.M., Vega G.L., McGovern M.E., et al. Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of Niaspan trial. Arch Int Med 162 (2002) 1568-1576
    • (2002) Arch Int Med , vol.162 , pp. 1568-1576
    • Grundy, S.M.1    Vega, G.L.2    McGovern, M.E.3
  • 35
    • 33748038025 scopus 로고    scopus 로고
    • Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery disease
    • Kuvin J.T., Dave D.M., Sliney K.A., et al. Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery disease. Am J Cardiol 98 (2006) 743-745
    • (2006) Am J Cardiol , vol.98 , pp. 743-745
    • Kuvin, J.T.1    Dave, D.M.2    Sliney, K.A.3
  • 36
    • 17044375852 scopus 로고    scopus 로고
    • Adiponectin: identification, physiology and clinical relevance in metabolic and vascular disease
    • Matsuzawa Y. Adiponectin: identification, physiology and clinical relevance in metabolic and vascular disease. Atheroscler Suppl 6 (2005) 7-14
    • (2005) Atheroscler Suppl , vol.6 , pp. 7-14
    • Matsuzawa, Y.1


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