Changes in the free energy profile of glutamate mutase imparted by the mutation of an active site arginine residue to lysine

Archives of Biochemistry and Biophysics

Volumn 461, Issue 2, 2007, Pages 194-199

  Patwardhan, Anjali ^a   Marsh, E Neil G ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Coenzyme B12; Enzyme; Free energy profile; Isomerization; Isotope effect; Isotope partitioning; Protein radical

Indexed keywords

ARGININE; FREE RADICAL; LYSINE; METHYLASPARTATE MUTASE; MUTANT PROTEIN; MUTASE; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; COENZYME; CONTROLLED STUDY; ELECTRICITY; ENERGY; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; MUTATION; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ARGININE; BINDING SITES; INTRAMOLECULAR TRANSFERASES; KINETICS; LYSINE; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 34247570946     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2007.01.010     Document Type: Article

References (36)

1. Barker H.A., Rooze V., Suzuki F., and Iodice A.A. J. Biol. Chem. 239 (1964) 3260-3266
2. Buckel W., and Barker H.A. J. Bacteriol. 117 (1974) 1248-1260
3. Holloway D.E., and Marsh E.N.G. J. Biol. Chem. 269 (1994) 20425-20430
4. Chen H.P., and Marsh E.N.G. Biochemistry 36 (1997) 14939-14945
5. Banerjee R. Chem. Biol. 4 (1997) 175-186
6. Buckel W., and Golding B.T. Chem. Soc. Rev. 25 (1996) 329-337
7. Marsh E.N.G., and Drennan C.L. Curr. Opin. Chem. Biol. 5 (2001) 499-505
8. Banerjee R. Biochemistry 40 (2001) 6191-6198
9. Gruber K., and Kratky C. Curr. Opin. Chem. Biol. 6 (2002) 598-603
10. Toraya T. Chem. Rev. 103 (2003) 2095-2127
11. Reitzer R., Gruber K., Jogl G., Wagner U.G., Bothe H., Buckel W., and Kratky C. Structure 7 (1999) 891-902
12. Gruber K., Reitzer R., and Kratky C. Angew. Chem. Intl. Edn. 40 (2001) 3377
13. Cheng M.-C., and Marsh E.N.G. Biochemistry 44 (2005) 2686-2691
14. Brooks A.J., Fox C.C., Marsh E.N.G., Vlasie M., Banerjee R., and Brunold T.C. Biochemistry 44 (2005) 15167-15181
15. Cheng M.-C., and Marsh E.N.G. Biochemistry 43 (2004) 2155-2158
16. Huhta M.S., Ciceri D., Golding B.T., and Marsh E.N.G. Biochemistry 41 (2002) 3200-3206
17. Huhta M.S., Chen H.-P., Hemann C., Hille C.R., and Marsh E.N.G. Biochem. J. 355 (2001) 131-137
18. Chih H.-W., and Marsh E.N.G. J. Am. Chem. Soc. 122 (2000) 10732-10733
19. Roymoulik I., Moon N., Dunham W.R., Ballou D.P., and Marsh E.N.G. Biochemistry 39 (2000) 10340-10346
20. Chih H.-W., and Marsh E.N.G. Biochemistry 38 (1999) 13684-13691
21. Bothe H., Darley D.J., Albracht S.P., Gerfen G.J., Golding B.T., and Buckel W. Biochemistry 37 (1998) 4105-4113
22. Marsh E.N.G., and Ballou D.P. Biochemistry 37 (1998) 11864-11872
23. Chen H.P., and Marsh E.N.G. Biochemistry 36 (1997) 7884-7889
24. Madhavapeddi P., and Marsh E.N.G. Chem. Biol. 8 (2001) 1143-1149
25. Madhavapeddi P., Ballou D.P., and Marsh E.N.G. Biochemistry 41 (2002) 15802-15809
26. Xia L., Ballou D.P., and Marsh E.N.G. Biochemistry 43 (2004) 3238-3245
27. Chih H.-W., and Marsh E.N.G. Biochemistry 40 (2001) 13060-13067
28. Meier T.W., Thoma N.H., and Leadlay P.F. Biochemistry 35 (1996) 11791-11796
29. Thoma N.H., Meier T.W., Evans P.R., and Leadlay P.F. Biochemistry 37 (1998) 14386-14393
30. Thoma N.H., Evans P.R., and Leadlay P.F. Biochemistry 39 (2000) 9213-9221
31. Marsh E.N.G. Biochemistry 34 (1995) 7542-7547
32. Smith D.M., Golding B.T., and Radom L. J. Am. Chem. Soc. 121 (1999) 9388-9399
33. Smith D.M., Golding B.T., and Radom L. J. Am. Chem. Soc. 123 (2001) 1664-1675
34. Wetmore S.D., Smith D.M., and Radom L. J. Am. Chem. Soc. 123 (2001) 8678-8689
35. Wetmore S.D., Smith D.M., Bennett J.T., and Radom L. J. Am. Chem. Soc. 124 (2002) 14054-14065
36. Wetmore S.D., Smith D.M., Golding B.T., and Radom L. J. Am. Chem. Soc. 123 (2001) 7963-7972