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Volumn 8, Issue 12, 2001, Pages 1143-1149

The role of the active site glutamate in the rearrangement of glutamate to 3-methylaspartate catalyzed by adenosylcobalamin-dependent glutamate mutase

Author keywords

Coenzyme B12; Enzyme; Free radical; Isotope effect; Mutagenesis

Indexed keywords

3 METHYLASPARTIC ACID; 3-METHYLASPARTIC ACID; ASPARTIC ACID; COBAMAMIDE; DRUG DERIVATIVE; GLUTAMIC ACID; METHYLASPARTATE MUTASE; MUTASE;

EID: 0035542850     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00081-3     Document Type: Article
Times cited : (19)

References (23)
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    • Marsh, E.N.G.1
  • 8
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    • Coupling of cobalt-carbon bond homolysis and hydrogen atom abstraction in adenosylcobalamin-dependent glutamate mutase
    • (1998) Biochemistry , vol.37 , pp. 11864-11872
    • Marsh, E.N.G.1    Ballou, D.P.2
  • 9
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    • Evidence that cobalt-carbon bond homolysis is coupled to hydrogen atom abstraction from substrate in methylmalonyl-CoA mutase
    • (1997) Biochemistry , vol.36 , pp. 3713-3718
    • Padmakumar, R.1    Banerjee, R.2
  • 10
    • 0034601785 scopus 로고    scopus 로고
    • Isotope effects in the transient phases of the reaction catalyzed by ethanolamine ammonia-lyase: Determination of the number of exchangeable hydrogens in the enzyme-cofactor complex
    • (2000) Biochemistry , vol.39 , pp. 12069-12075
    • Bandarian, V.1    Reed, G.H.2
  • 11
    • 0034326618 scopus 로고    scopus 로고
    • Mechanism of glutamate mutase: Identification and kinetic competence of acrylate and glycyl radical as intermediates in the rearrangment of glutamate to methylaspartate
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 10732-10733
    • Chih, H.-W.1    Marsh, E.N.G.2
  • 14
    • 0028088469 scopus 로고
    • Adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum. Overexpression in Escherichia coli, purification, and characterization of the recombinant enzyme
    • (1994) J. Biol. Chem. , vol.269 , pp. 20425-20430
    • Holloway, D.E.1    Marsh, E.N.G.2
  • 16
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    • Adenosylcobalamin-dependent glutamate mutase: Examination of substrate and coenzyme binding in an engineered fusion protein possessing simplified subunit structure and kinetic properties
    • (1997) Biochemistry , vol.36 , pp. 14939-14945
    • Chen, H.P.1    Marsh, E.N.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.