-
1
-
-
0034788672
-
Unusual enzymes involved in five pathways of glutamate fermentation
-
Buckel W. Unusual enzymes involved in five pathways of glutamate fermentation. Appl Microbiol Biotechnol. 57:2001;263-273.
-
(2001)
Appl Microbiol Biotechnol
, vol.57
, pp. 263-273
-
-
Buckel, W.1
-
3
-
-
0028088469
-
Adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum - Overexpression in Escherichia coli, purification, and characterization of the recombinant enzyme
-
Holloway D.E., Marsh E.N.G. Adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum - overexpression in Escherichia coli, purification, and characterization of the recombinant enzyme. J Biol Chem. 269:1994;20425-20430.
-
(1994)
J Biol Chem
, vol.269
, pp. 20425-20430
-
-
Holloway, D.E.1
Marsh, E.N.G.2
-
5
-
-
0028172856
-
12-dependent glutamate mutase from Clostridium cochlearium produced in Escherichia coli
-
12-dependent glutamate mutase from Clostridium cochlearium produced in Escherichia coli. Eur J Biochem. 226:1994;577-585.
-
(1994)
Eur J Biochem
, vol.226
, pp. 577-585
-
-
Zelder, O.1
Beatrix, B.2
Leutbecher, U.3
Buckel, W.4
-
6
-
-
0342601068
-
Adenosylcobalamin-dependent glutamate mutase - Examination of substrate and coenzyme binding in an engineered fusion protein possessing simplified subunit structure and kinetic properties
-
Chen H.P., Marsh E.N.G. Adenosylcobalamin-dependent glutamate mutase - examination of substrate and coenzyme binding in an engineered fusion protein possessing simplified subunit structure and kinetic properties. Biochemistry. 36:1997;14939-14945.
-
(1997)
Biochemistry
, vol.36
, pp. 14939-14945
-
-
Chen, H.P.1
Marsh, E.N.G.2
-
8
-
-
0034567782
-
Adenosylcobalamin-dependent enzymes
-
A. Holzenburg, & N.S. Scrutton. New York: Kluwer Academic/Plenum Publishers
-
Marsh E.N.G., Holloway D.E. Adenosylcobalamin-dependent enzymes. Holzenburg A., Scrutton N.S., Subcellular Biochemistry. 35:2000;351-404 Kluwer Academic/Plenum Publishers, New York.
-
(2000)
Subcellular Biochemistry
, vol.35
, pp. 351-404
-
-
Marsh, E.N.G.1
Holloway, D.E.2
-
9
-
-
0035967504
-
12-dependent enzymes
-
12-dependent enzymes. Biochemistry. 40:2001;6191-6198.
-
(2001)
Biochemistry
, vol.40
, pp. 6191-6198
-
-
Banerjee, R.1
-
10
-
-
0035478124
-
Adenosylcobalamin-dependent isomerases: New insights into structure and mechanism
-
Marsh E.N.G., Drennan C.L. Adenosylcobalamin-dependent isomerases: New insights into structure and mechanism. Curr Opin Chem Biol. 5:2001;499-505.
-
(2001)
Curr Opin Chem Biol
, vol.5
, pp. 499-505
-
-
Marsh, E.N.G.1
Drennan, C.L.2
-
11
-
-
0033849103
-
12-dependent glutamate mutase
-
12-dependent glutamate mutase. Bioorg Chem. 28:2000;176-189.
-
(2000)
Bioorg Chem
, vol.28
, pp. 176-189
-
-
Marsh, E.N.G.1
-
12
-
-
0011137970
-
Glutamate mutase
-
K. Wieghardt, R. Huber, T.L. Poulos, & A. Messerschmidt. Chichester, UK: John Wiley & Sons
-
Kratky C., Gruber K. Glutamate mutase. Wieghardt K., Huber R., Poulos T.L., Messerschmidt A., Handbook of Metalloproteins. 2001;983-994 John Wiley & Sons, Chichester, UK.
-
(2001)
Handbook of Metalloproteins
, pp. 983-994
-
-
Kratky, C.1
Gruber, K.2
-
14
-
-
0030584657
-
12 radicals are generated: The crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution
-
12 radicals are generated: The crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution. Structure. 4:1996;339-350.
-
(1996)
Structure
, vol.4
, pp. 339-350
-
-
Mancia, F.1
Keep, N.H.2
Nakagawa, A.3
Leadlay, P.F.4
McSweeney, S.5
Rasmussen, B.6
Bosecke, P.7
Diat, O.8
Evans, P.R.9
-
17
-
-
0033596289
-
12-dependent enzymes glutamate mutase and 2-methyleneglutarate mutase
-
12-dependent enzymes glutamate mutase and 2-methyleneglutarate mutase. J Am Chem Soc. 121:1999;11780-11789.
-
(1999)
J Am Chem Soc
, vol.121
, pp. 11780-11789
-
-
Champloy, F.1
Jogl, G.2
Reitzer, R.3
Buckel, W.4
Bothe, H.5
Michalowicz, A.6
Meyer-Klaucke, W.7
Kratky, C.8
-
24
-
-
0035310673
-
Protein-coenzyme interactions in adenosylcobalamin-dependent glutamate mutase
-
Huhta M.S., Chen H.-P., Hemann C., Hille C.R., Marsh E.N.G. Protein-coenzyme interactions in adenosylcobalamin-dependent glutamate mutase. Biochem J. 355:2001;131-137.
-
(2001)
Biochem J
, vol.355
, pp. 131-137
-
-
Huhta, M.S.1
Chen, H.-P.2
Hemann, C.3
Hille, C.R.4
Marsh, E.N.G.5
-
25
-
-
0035903592
-
12-dependent enzyme glutamate mutase
-
12-dependent enzyme glutamate mutase. Angew Chem Int Ed Engl. 40:2001;3377-3380. Highresolution crystallography on active GLM in the presence of substrate demonstrates that the transfer of the 5′-desoxyadenosyl radical from the cobalt atom to the substrate is sterically controlled by furanose pseudorotation.
-
(2001)
Angew Chem Int Ed Engl
, vol.40
, pp. 3377-3380
-
-
Gruber, K.1
Reitzer, R.2
Kratky, C.3
-
26
-
-
0025230340
-
Enzymatic-reaction selectivity by negative catalysis or how do enzymes deal with highly reactive intermediates
-
Retey J. Enzymatic-reaction selectivity by negative catalysis or how do enzymes deal with highly reactive intermediates. Angew Chem Int Ed Engl. 29:1990;355-361.
-
(1990)
Angew Chem Int Ed Engl
, vol.29
, pp. 355-361
-
-
Retey, J.1
-
30
-
-
0034834182
-
12-dependent carbon-skeleton rearrangement
-
12-dependent carbon-skeleton rearrangement. J Am Chem Soc. 123:2001;7963-7972. Quantum chemical calculations suggest that partial proton transfer to the carboxyl and from the ammonium group of the substrate derived radical will facilitate its fragmentation.
-
(2001)
J Am Chem Soc
, vol.123
, pp. 7963-7972
-
-
Wetmore, S.D.1
Smith, D.M.2
Golding, B.T.3
Radom, L.4
-
31
-
-
0017171488
-
On the mechanism of action of adenosylcobalamin
-
Golding B.T., Radom L. On the mechanism of action of adenosylcobalamin. J Am Chem Soc. 98:1976;6331-6338.
-
(1976)
J Am Chem Soc
, vol.98
, pp. 6331-6338
-
-
Golding, B.T.1
Radom, L.2
-
32
-
-
0034326618
-
Mechanism of glutamate mutase: Identification and kinetic competence of acrylate and glycyl radical as intermediates in the rearrangement of glutamate to methylaspartate
-
Chih H.-W., Marsh E.N.G. Mechanism of glutamate mutase: identification and kinetic competence of acrylate and glycyl radical as intermediates in the rearrangement of glutamate to methylaspartate. J Am Chem Soc. 122:2000;10732-10733. Rapidquench experiments yield the first direct experimental evidence for the transient formation of a glycyl radical and an acrylate ion during the GLM-catalyzed rearrangement.
-
(2000)
J Am Chem Soc
, vol.122
, pp. 10732-10733
-
-
Chih, H.-W.1
Marsh, E.N.G.2
-
36
-
-
0033552235
-
12-dependent methylmalonyl-CoA mutase: Partial proton transfer in action
-
12-dependent methylmalonyl-CoA mutase: partial proton transfer in action. J Am Chem Soc. 121:1999;9388-9399.
-
(1999)
J Am Chem Soc
, vol.121
, pp. 9388-9399
-
-
Smith, D.M.1
Golding, B.T.2
Radom, L.3
-
37
-
-
0033540690
-
12: Theoretical studies of the 2-methyleneglutarate mutase catalyzed rearrangement
-
12: theoretical studies of the 2-methyleneglutarate mutase catalyzed rearrangement. J Am Chem Soc. 121:1999;1037-1044.
-
(1999)
J Am Chem Soc
, vol.121
, pp. 1037-1044
-
-
Smith, D.M.1
Golding, B.T.2
Radom, L.3
-
38
-
-
0035980224
-
Tritium partitioning and isotope effects in adenosylcobalamin-dependent glutamate mutase
-
Chih H.-W., Marsh E.N.G. Tritium partitioning and isotope effects in adenosylcobalamin-dependent glutamate mutase. Biochemistry. 40:2001;13060-13067.
-
(2001)
Biochemistry
, vol.40
, pp. 13060-13067
-
-
Chih, H.-W.1
Marsh, E.N.G.2
-
39
-
-
0035542850
-
The role of the active site glutamate in the rearrangement of glutamate to 3-methylaspartate catalyzed by adenosylcobalamin-dependent glutamate mutase
-
Madhavapeddi P., Marsh E.N.G. The role of the active site glutamate in the rearrangement of glutamate to 3-methylaspartate catalyzed by adenosylcobalamin-dependent glutamate mutase. Chem Biol. 8:2001;1143-1149. Mutational studies suggest an important but not crucial role of Glu171 for substrate rearrangement (but not for substrate binding).
-
(2001)
Chem Biol
, vol.8
, pp. 1143-1149
-
-
Madhavapeddi, P.1
Marsh, E.N.G.2
-
40
-
-
0033597361
-
The reaction of the substrate analog 2-ketoglutarate with adenosylcobalamin-dependent glutamate mutase
-
Roymoulik I., Chen H.P., Marsh E.N.G. The reaction of the substrate analog 2-ketoglutarate with adenosylcobalamin-dependent glutamate mutase. J Biol Chem. 274:1999;11619-11622.
-
(1999)
J Biol Chem
, vol.274
, pp. 11619-11622
-
-
Roymoulik, I.1
Chen, H.P.2
Marsh, E.N.G.3
-
42
-
-
0037022798
-
A novel reaction between adenosylcobalamin and 2-methyleneglutarate catalyzed by glutamate mutase
-
Huhta M.S., Ciceri D., Golding B.T., Marsh E.N.G. A novel reaction between adenosylcobalamin and 2-methyleneglutarate catalyzed by glutamate mutase. Biochemistry. 41:2002;3200-3206. Incubation of GLM with 2-methyleneglutarate leads to enzyme inactivation through formation of a covalent bond between the adenosyl radical and the exo-methylene group of the inhibitor.
-
(2002)
Biochemistry
, vol.41
, pp. 3200-3206
-
-
Huhta, M.S.1
Ciceri, D.2
Golding, B.T.3
Marsh, E.N.G.4
-
43
-
-
0026244229
-
MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
-
Kraulis P.J. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J Appl Crystallogr. 24:1991;946-950.
-
(1991)
J Appl Crystallogr
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
44
-
-
0030815133
-
Raster3D: Photorealistic molecular graphics
-
Merritt E.A., Bacon D.J. Raster3D: photorealistic molecular graphics. Meth Enzymol. 277:1997;505-524.
-
(1997)
Meth Enzymol
, vol.277
, pp. 505-524
-
-
Merritt, E.A.1
Bacon, D.J.2
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