Nucleotide pyrophosphatase/phosphodiesterase 1 is responsible for degradation of antisense phosphorothioate oligonucleotides

Oligonucleotides

Volumn 17, Issue 1, 2007, Pages 134-145

  Wójcik, Marzena ^a   Cieślak, Marcin ^a   Stec, Wojciech J ^a   Goding, James W ^b   Koziołkiewicz, Maria ^a,c  

^a CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

^b MONASH UNIVERSITY   (Australia)

^c LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ANTISENSE OLIGONUCLEOTIDE; CELL ANTIGEN; DEOXYADENOSINE; ENDONUCLEASE; NUCLEOTIDE PYROPHOSPHATASE; PHOSPHODIESTERASE I; PHOSPHOROTHIOIC ACID DERIVATIVE; PLASMA CELL DIFFERENTIATION ANTIGEN PC 1; SPLEEN EXONUCLEASE; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; DEGRADATION; ENZYME ACTIVITY; HUMAN; HYDROLYSIS; NUCLEOTIDE SEQUENCE; PLASMA; PRIORITY JOURNAL; SYNTHESIS;

ENZYME INHIBITORS; EXONUCLEASES; HUMANS; IMMUNOPRECIPITATION; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; SUBSTRATE SPECIFICITY; THIONUCLEOTIDES;

EID: 34247526364     PISSN: 15454576     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.2007.0021     Document Type: Article

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