-
1
-
-
0037039374
-
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer
-
Barak Y, Liao D, He W, Ong ES, Nelson MC, Olefsky JM, Boland R, Evans RM (2002) Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci USA 99:303-308
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 303-308
-
-
Barak, Y.1
Liao, D.2
He, W.3
Ong, E.S.4
Nelson, M.C.5
Olefsky, J.M.6
Boland, R.7
Evans, R.M.8
-
2
-
-
33644645013
-
PPAR delta: A dagger in the heart of the metabolic syndrome
-
Barish GD, Narkar VA, Evans RM (2006) PPAR delta: a dagger in the heart of the metabolic syndrome. J Clin Invest 116:590-597
-
(2006)
J Clin Invest
, vol.116
, pp. 590-597
-
-
Barish, G.D.1
Narkar, V.A.2
Evans, R.M.3
-
3
-
-
0030047806
-
Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
-
Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137:354-366
-
(1996)
Endocrinology
, vol.137
, pp. 354-366
-
-
Braissant, O.1
Foufelle, F.2
Scotto, C.3
Dauca, M.4
Wahli, W.5
-
4
-
-
9144262378
-
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
-
Cheng L, Ding G, Qin Q, Huang Y, Lewis W, He N, Evans RM, Schneider MD, Brako FA, Xiao Y, Chen YE, Yang Q (2004a) Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nat Med 10:1245-1250
-
(2004)
Nat Med
, vol.10
, pp. 1245-1250
-
-
Cheng, L.1
Ding, G.2
Qin, Q.3
Huang, Y.4
Lewis, W.5
He, N.6
Evans, R.M.7
Schneider, M.D.8
Brako, F.A.9
Xiao, Y.10
Chen, Y.E.11
Yang, Q.12
-
5
-
-
0345735302
-
Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes
-
Cheng L, Ding G, Qin Q, Xiao Y, Woods D, Chen YE, Yang Q (2004b) Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes. Biochem Biophys Res Commun 313:277-286
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 277-286
-
-
Cheng, L.1
Ding, G.2
Qin, Q.3
Xiao, Y.4
Woods, D.5
Chen, Y.E.6
Yang, Q.7
-
6
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans RM, Barish GD, Wang YX (2004) PPARs and the complex journey to obesity. Nat Med 10:355-361
-
(2004)
Nat Med
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
Wang, Y.X.3
-
7
-
-
0034700110
-
Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer
-
Gupta RA, Tan J, Krause WF, Geraci MW, Willson TM, Dey SK, DuBois RN (2000) Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proc Natl Acad Sci USA 97:13275-13280
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13275-13280
-
-
Gupta, R.A.1
Tan, J.2
Krause, W.F.3
Geraci, M.W.4
Willson, T.M.5
Dey, S.K.6
DuBois, R.N.7
-
8
-
-
1942470331
-
Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
-
Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN (2004) Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nat Med 10:245-247
-
(2004)
Nat Med
, vol.10
, pp. 245-247
-
-
Gupta, R.A.1
Wang, D.2
Katkuri, S.3
Wang, H.4
Dey, S.K.5
DuBois, R.N.6
-
9
-
-
0033615352
-
PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
-
He TC, Chan TA, Vogelstein B, Kinzler KW (1999) PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99:335-345
-
(1999)
Cell
, vol.99
, pp. 335-345
-
-
He, T.C.1
Chan, T.A.2
Vogelstein, B.3
Kinzler, K.W.4
-
10
-
-
33645004402
-
PPAR beta/delta selectively induces differentiation and inhibits cell proliferation
-
Kim DJ, Bility MT, Billin AN, Willson TM, Gonzalez FJ, Peters JM (2006) PPAR beta/delta selectively induces differentiation and inhibits cell proliferation. Cell Death Differ 13:53-60
-
(2006)
Cell Death Differ
, vol.13
, pp. 53-60
-
-
Kim, D.J.1
Bility, M.T.2
Billin, A.N.3
Willson, T.M.4
Gonzalez, F.J.5
Peters, J.M.6
-
11
-
-
0028321529
-
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
-
Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci USA 91:7355-7359
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7355-7359
-
-
Kliewer, S.A.1
Forman, B.M.2
Blumberg, B.3
Ong, E.S.4
Borgmeyer, U.5
Mangelsdorf, D.J.6
Umesono, K.7
Evans, R.M.8
-
12
-
-
33144455156
-
Peroxisome proliferatoractivated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage
-
Lee CH, Kang K, Mehl I, Nofsinger R, Alaynick WA, Chong LW, Rosenfeld JM, Evans RM (2006a) Peroxisome proliferatoractivated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage. Proc Natl Acad Sci USA 103:2434-2439
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2434-2439
-
-
Lee, C.H.1
Kang, K.2
Mehl, I.3
Nofsinger, R.4
Alaynick, W.A.5
Chong, L.W.6
Rosenfeld, J.M.7
Evans, R.M.8
-
13
-
-
33644766913
-
PPAR delta regulates glucose metabolism and insulin sensitivity
-
Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM (2006b) PPAR delta regulates glucose metabolism and insulin sensitivity. Proc Natl Acad Sci USA 103:3444-3449
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3444-3449
-
-
Lee, C.H.1
Olson, P.2
Hevener, A.3
Mehl, I.4
Chong, L.W.5
Olefsky, J.M.6
Gonzalez, F.J.7
Ham, J.8
Kang, H.9
Peters, J.M.10
Evans, R.M.11
-
14
-
-
0035956850
-
Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
-
Park BH, Vogelstein B, Kinzler KW (2001) Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc Natl Acad Sci USA 98:2598-2603
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2598-2603
-
-
Park, B.H.1
Vogelstein, B.2
Kinzler, K.W.3
-
15
-
-
33645753739
-
GW-501516 GlaxoSmithKline/Ligand
-
Pelton P (2006) GW-501516 GlaxoSmithKline/Ligand. Curr Opin Investig Drugs 7:360-370
-
(2006)
Curr Opin Investig Drugs
, vol.7
, pp. 360-370
-
-
Pelton, P.1
-
16
-
-
0033625677
-
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor beta(delta)
-
Peters JM, Lee SS, Li W, Ward JM, Gavrilova O, Everett C, Reitman ML, Hudson LD, Gonzalez FJ (2000) Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor beta(delta). Mol Cell Biol 20:5119-5128
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5119-5128
-
-
Peters, J.M.1
Lee, S.S.2
Li, W.3
Ward, J.M.4
Gavrilova, O.5
Everett, C.6
Reitman, M.L.7
Hudson, L.D.8
Gonzalez, F.J.9
-
17
-
-
2342579597
-
Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes
-
Schmuth M, Haqq CM, Cairns WJ, Holder JC, Dorsam S, Chang S, Lau P, Fowler AJ, Chuang G, Moser AH, Brown BE, Mao-Qiang M, Uchida Y, Schoonjans K, Auwerx J, Chambon P, Willson TM, Elias PM, Feingold KR (2004) Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. J Invest Dermatol 122:971-983
-
(2004)
J Invest Dermatol
, vol.122
, pp. 971-983
-
-
Schmuth, M.1
Haqq, C.M.2
Cairns, W.J.3
Holder, J.C.4
Dorsam, S.5
Chang, S.6
Lau, P.7
Fowler, A.J.8
Chuang, G.9
Moser, A.H.10
Brown, B.E.11
Mao-Qiang, M.12
Uchida, Y.13
Schoonjans, K.14
Auwerx, J.15
Chambon, P.16
Willson, T.M.17
Elias, P.M.18
Feingold, K.R.19
-
18
-
-
0018415470
-
Differential effects of somatostatin analogues on alpha- and beta-cells of the pancreas
-
Taborsky GJ Jr, Smith PH, Porte D Jr (1979) Differential effects of somatostatin analogues on alpha- and beta-cells of the pancreas. Am J Physiol 236:E123-E128
-
(1979)
Am J Physiol
, vol.236
-
-
Taborsky Jr, G.J.1
Smith, P.H.2
Porte Jr, D.3
-
19
-
-
33646792244
-
Peroxisome proliferator-activated receptor delta (PPARdelta), a novel target site for drug discovery in metabolic syndrome
-
Takahashi S, Tanaka T, Kodama T, Sakai J (2006) Peroxisome proliferator-activated receptor delta (PPARdelta), a novel target site for drug discovery in metabolic syndrome. Pharmacol Res 53:501-507
-
(2006)
Pharmacol Res
, vol.53
, pp. 501-507
-
-
Takahashi, S.1
Tanaka, T.2
Kodama, T.3
Sakai, J.4
-
20
-
-
0035893364
-
Critical roles of PPAR beta/delta in keratinocyte response to inflammation
-
Tan NS, Michalik L, Noy N, Yasmin R, Pacot C, Heim M, Fluhmann B, Desvergne B, Wahli W (2001) Critical roles of PPAR beta/delta in keratinocyte response to inflammation. Genes Dev 15:3263-3277
-
(2001)
Genes Dev
, vol.15
, pp. 3263-3277
-
-
Tan, N.S.1
Michalik, L.2
Noy, N.3
Yasmin, R.4
Pacot, C.5
Heim, M.6
Fluhmann, B.7
Desvergne, B.8
Wahli, W.9
-
21
-
-
17744392617
-
Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid
-
Westergaard M, Henningsen J, Svendsen ML, Johansen C, Jensen UB, Schroder HD, Kratchmarova I, Berge RK, Iversen L, Bolund L, Kragballe K, Kristiansen K (2001) Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. J Invest Dermatol 116:702-712
-
(2001)
J Invest Dermatol
, vol.116
, pp. 702-712
-
-
Westergaard, M.1
Henningsen, J.2
Svendsen, M.L.3
Johansen, C.4
Jensen, U.B.5
Schroder, H.D.6
Kratchmarova, I.7
Berge, R.K.8
Iversen, L.9
Bolund, L.10
Kragballe, K.11
Kristiansen, K.12
-
22
-
-
0037192764
-
Peroxisome proliferator-activated receptor delta is up-regulated during vascular lesion formation and promotes post-confluent cell proliferation in vascular smooth muscle cells
-
Zhang J, Fu M, Zhu X, Xiao Y, Mou Y, Zheng H, Akinbami MA, Wang Q, Chen YE (2002) Peroxisome proliferator-activated receptor delta is up-regulated during vascular lesion formation and promotes post-confluent cell proliferation in vascular smooth muscle cells. J Biol Chem 277:11505-11512
-
(2002)
J Biol Chem
, vol.277
, pp. 11505-11512
-
-
Zhang, J.1
Fu, M.2
Zhu, X.3
Xiao, Y.4
Mou, Y.5
Zheng, H.6
Akinbami, M.A.7
Wang, Q.8
Chen, Y.E.9
|