Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia

Journal of Neurochemistry

Volumn 101, Issue 3, 2007, Pages 806-814

  Nguyen, Nga H T ^a   Morland, Cecilie ^a,b   Gonzalez, Susana Villa ^a,b   Rise, Frode ^b   Storm Mathisen, Jon ^b   Gundersen, Vidar ^b   Hassel, Bjørnar ^a  

^a NORWEGIAN DEFENCE RESEARCH ESTABLISHMENT FFI   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Anaplerosis; Cerebellar granule cells; Histone H4; Metabolism; Propionyl CoA synthetase; Pyruvate carboxylation

Indexed keywords

CARBON 14; GLUTAMATE AMMONIA LIGASE; HISTONE; ISOLEUCINE; MITOCHONDRIAL ENZYME; PROPIONIC ACID; PROPIONYL COENZYME A CARBOXYLASE;

ACETYLATION; AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN METABOLISM; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; ENZYME RELEASE; FEMALE; GENE EXPRESSION; GLIA; INTRACELLULAR SPACE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPIONIC ACIDEMIA;

ACETYLATION; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELLS, CULTURED; CEREBELLUM; FEMALE; HISTONES; ISOTOPES; MICE; MODELS, BIOLOGICAL; NEUROGLIA; NEURONS; PROPIONATES; RATS; TIME FACTORS;

MUS;

EID: 34247402503     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04397.x     Document Type: Article

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