Ascorbic acid prevents cognitive deficits caused by chronic administration of propionic acid to rats in the water maze

Pharmacology Biochemistry and Behavior

Volumn 73, Issue 3, 2002, Pages 623-629

  Pettenuzzo, Leticia F ^a   Schuck, Patrícia F ^a   Fontella, Fernanda ^a   Wannmacher, Clóvis M D ^a   Wyse, Ângela T ^a   Dutra Filho, Carlos S ^a   Netto, Carlos Alexandre ^a   Wajner, Moacir ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Antioxidants; Ascorbic acid; Propionic acid; Propionic acidemia; Water maze

Indexed keywords

ASCORBIC ACID; FREE RADICAL; PROPIONIC ACID; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE;

AGE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; BODY WEIGHT; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEPTH PERCEPTION; DRUG EFFECT; FEMALE; HIPPOCAMPUS; MALE; MAZE TEST; MENTAL TASK; NEUROPATHOLOGY; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PERINATAL PERIOD; PRIORITY JOURNAL; PROPIONIC ACIDEMIA; RAT;

ANIMALIA;

EID: 0036342519     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(02)00856-0     Document Type: Article

References (31)

1. Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases
2. Global ischemia an behavioral deficits
3. Global ischemic neuronal damage relates to behavioral deficits: A pharmacological approach
4. The antioxidant LY 231617 ameliorates functional and morphological sequelae induced by global ischemia in rats
5. 2 production in cerebellum and cerebral cortex of suckling rats
6. Effect of chemically induced propionic acidemia on neurobehavioral development of rats
7. Biochemical and clinical effects of an antioxidative supplementation of geriatric patients
8. Metabolism and function of gangliosides in developing neurons
9. Prospects for new restorative and neuroprotective treatments in Parkinson's disease
10. Inhibition of succinate dehydrogenase and beta-hydroxybutyrate dehydrogenase activities by methylmalonate in brain and liver of developing rats
11. Disorders of propionate and methylmalonate metabolism
12. Propionic and L-methylmalonic acids induce oxidative stress in brain of young rats
13. Oxygen radicals as key mediators in neurological disease: Fact or fiction?
14. Role of free radicals in aging and disease
15. Physiology and pathophysiology of organic acids in cerebrospinal fluid
16. Luminol luminescence induced by 2,2′-azo-bis (2-amidinopropane) thermolysis
17. Antioxidant enzymes and human diseases
18. Propionate mitochondrial toxicity in liver and skeletal muscle: Acyl CoA levels
19. Place navigation impaired in rats with hippocampal lesions
20. Tocopherol in inborn errors of intermediary metabolism
21. Propionic acid stimulates superoxide generation in human neutrophils
22. Effects of fetal hippocampal field grafts on ischaemic-induced deficits in spatial navigation in the water maze
23. Oxidative injury in diseases of the central nervous system: Focus on Alzheimer's disease
24. The relation between antioxidants and memory performance in the old and very old
25. Ganglioside stimulation of axonal sprouting in vivo
26. Chronic antioxidant treatment improves the cognitive performance of aged rats
27. The open-field test: A critical review
28. Sex differences and estropausal phase effects on water maze performance in aged rats
29. Quantitative changes in DNA, RNA and protein during prenatal and postnatal growth in rat
30. +-ATPase from rat brain cortex by propionic acid