Impaired solute accumulation in inner medulla of Clcnk1-/- mice kidney

American Journal of Physiology - Renal Physiology

Volumn 280, Issue 1 49-1, 2001, Pages

  Akizuki, Norikazu ^a   Uchida, Shinichi ^a   Sasaki, Sei ^a   Marumo, Fumiaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Aquaporin 2 water channel; Chloride channel; Countercurrent system; Knockout mouse; Osmolytes

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSTERONE; AQUAPORIN; CHLORIDE CHANNEL; CHLORIDE ION; CREATININE; MESSENGER RNA; SODIUM ION; UREA; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COUNTERCURRENT FLOW; CREATININE CLEARANCE; KIDNEY CONCENTRATING CAPACITY; KIDNEY MEDULLA; KNOCKOUT MOUSE; MALE; MOUSE; NEPHROGENIC DIABETES INSIPIDUS; NONHUMAN; OSMOTIC DIURESIS; POLYURIA; PRIORITY JOURNAL; URINARY EXCRETION; URINE OSMOLALITY;

EID: 0035017899     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2001.280.1.f79     Document Type: Article

References (32)

1. Adachi S, Uchida S, Ito H, Hata M, Hiroe M, Marumo F, and Sasaki S. Two isoforms of a chloride channel predominantly expressed in thick ascending limb of Henle's loop and collecting ducts of rat kidney. J Biol Chem 269: 17677-17683 1994.
2. Bagnasco S, Balaban R, Fales HM, Yang YM, and Burg M. Predominant osmotically active organic solutes in rat and rabbit renal medullas. J Biol Chem 261: 5872-5877, 1986.
3. Beck F, Dorge A, Rick R, and Thurau K. Intra- and extracellular element concentrations of rat renal papilla in antidiuresis. Kidney Int 25: 397-403, 1984.
4. Bondy CA, Lightman SL, and Lightman SL. Developmental and physiological regulation of aldose reductase mRNA expression in renal medulla. Mol Endocrinol 3: 1409-1416, 1989.
5. Burg MB. Molecular basis of osmotic regulation. Am J Physiol Renal Fluid Electrolyte Physiol 268: F983-F996, 1995.
6. Burg MB, Kwon ED, and Kultz D. Regulation of gene expression by hypertonicity. Annu Rev Physiol 59: 437-455, 1997.
7. Furuno M, Uchida S, Marumo F, and Sasaki S. Repressive regulation of the aquaporin-2 gene. Am J Physiol Renal Fluid Electrolyte Physiol 271: F854-F860, 1996.
8. Fushimi K, Sasaki S, Yamamoto T, Hayashi M, Furukawa T, Uchida S, Kuwahara M, Ishibashi K, Kawasaki M, Kihara I, and Marumo F. Functional characterization and cell immunolocalization of AQP-CD water channel in kidney collecting duct. Am J Physiol Renal Fluid Electrolyte Physiol 267: F573-F582, 1994.
9. Gamba G, Miyanoshita A, Lombardi M, Lytton J, Lee WS, Hediger MA, and Hebert SC. Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J Biol Chem 269: 17713-17722, 1994.
10. Greger R and Schlatter E. Properties of the lumen membranes of the cortical thick ascending limb of Henle's loop of rabbit kidney. Pflügers Arch 39: 315-324, 1983.
11. Hozawa S, Holtzman EJ, and Ausiello DA. cAMP motifs regulating transcription in the aquaporin 2 gene. Am J Physiol Cell Physiol 270: C1695-C1702, 1996.
12. Imai M and Kokko JP. Sodium, chloride, urea, and water transport in the thin ascending limb of Henle. Generation of osmotic gradients by passive diffusion of solutes. J Clin Invest 53: 393-402, 1974.
13. Imai M, Taniguchi J, and Tabei K. Function of thin loops of Henle. Kidney Int 31: 565-579, 1987.
14. Kettyle WM and Valtin H. Chemical and dimensional characterization of the renal countercurrent system in mice. Kidney Int 1: 135-144, 1972.
15. Kihara M, Umemura S, Sumida Y, Yokoyama N, Yabana M, Nyui N, Tamura K, Murakami K, Fukamizu A, and Ishii M. Genetic deficiency of angiotensinogen produces an impaired urine concentrating ability in mice. Kidney Int 53: 548-555, 1998.
16. Kokko JP and Rector FC Jr. Countercurrent multiplication system without active transport in inner medulla. Kidney Int 2: 214-223, 1972.
17. Matsumura Y, Uchida S, Kondo Y, Miyazaki H, Ko SB, Hayama A, Morimoto T, Liu W, Arisawa M, Sasaki S, and Marumo F. Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel. Nature Genet 21: 95-98, 1999.
18. Matsumura Y, Uchida S, Rai T, Sasaki S, and Marumo F. Transcriptional regulation of aquaporin-2 water channel gene by cAMP. J Am Soc Nephrol 8: 861-867, 1997.
19. Miyai A, Yamauchi A, Moriyama T, Kaneko T, Takenaka M, Sugiura T, Kitamura H, Ando A, Tohyama M, Shimada S, Imai E, and Kamada T. Expression of betaine transporter mRNA: its unique localization and rapid regulation in rat kidney. Kidney Int 50: 819-827, 1996.
20. Okubo S, Niimura F, Matsusaka T, Fogo A, Hogan BL, and Ichikawa I. Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption. Kidney Int 53: 617-625, 1998.
21. Paulais M and Teulon J. cAMP-activated chloride channel in the basolateral membrane of the thick ascending limb of the mouse kidney. J Membr Biol 113: 253-260, 1990.
22. Payne JA and Forbush B III. Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney. Proc Natl Acad Sci USA 91: 4544-4548, 1994.
23. Simon DB, Bindra RS, Mansfield TA, Nelson-Williams C, Mendonca E, Stone R, Schurman S, Nayir A, Alpay H, Bakkaloglu A, Rodriguez-Soriano J, Morales JM, Sanjad SA, Taylor CM, Pilz D, Brem A, Trachtman H, Griswold W, Richard GA, John E, and Lifton RP. Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III. Nature Genet. 17: 171-178, 1997.
24. Sizeland PC, Chambers ST, Lever M, Bason LM, and Robson RA. Short-term response of nonurea organic osmolytes in human kidney to a water load and water deprivation. Am J Physiol Renal Fluid Electrolyte Physiol 268: F227-F233, 1995.
25. - transport in ascending thin limb of Henle's loop in hamster. J Clin Invest 95: 1623-1627, 1995.
26. Takeuchi Y, Uchida S, Marumo F, and Sasaki S. Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney. Kidney Int 48: 1497-1503, 1995.
27. Uchida S, Sasaki S, Furukawa T, Hiraoka M, Imai T, Hirata Y, and Marumo F. Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla. J Biol Chem 268: 3821-3824, 1993.
28. Uchida S, Sasaki S, Nitta K, Uchida K, Horita S, Nihei H, and Marumo F. Localization and functional characterization of rat kidney-specific chloride channel, ClC-K1. J Clin Invest 95: 104-113, 1995.
29. Wirthensohn G, Lefrank S, Schmolke M, and Guder WG. Regulation of organic osmolyte concentrations in tubules from rat renal inner medulla. Am J Physiol Renal Fluid Electrolyte Physiol 256: F128-F135, 1989.
30. +/myo-inositol cotransporter in rat kidney. J Clin Invest 96: 1195-1201, 1995.
31. Yasui M, Zelenin SM, Celsi G, and Aperia A. Adenylate cyclase-coupled vasopressin receptor activates AQP2 promoter via a dual effect on CRE and AP1 elements. Am J Physiol Renal Physiol 272: F443-F450, 1997.
32. - conductance expression in Xenopus oocytes. Am J Physiol Renal Fluid Electrolyte Physiol 263: F979-F984, 1992.