Secondary hyperalgesia to mechanical but not heat stimuli following a capsaicin injection in hairy skin

Pain

Volumn 68, Issue 2-3, 1996, Pages 401-411

  Ali, Z ^a   Meyer, Richard A ^a   Campbell, J N ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

capsaicin; hyperalgesia; psychophysical

Indexed keywords

CAPSAICIN;

ARTICLE; CONTROLLED STUDY; ETIOLOGY; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; MECHANICAL STIMULATION; NOCICEPTION; NORMAL HUMAN; PAIN; PRIORITY JOURNAL; SKIN; THERMAL EXPOSURE;

ANALYSIS OF VARIANCE; CAPSAICIN; HAIR; HEAT; HUMANS; HYPERALGESIA; INJECTIONS, SUBCUTANEOUS; PAIN THRESHOLD; PSYCHOPHYSICS; SKIN; STRESS, MECHANICAL;

EID: 0030470085     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(96)03199-5     Document Type: Article

References (37)

1. Baumann, T.K., Simone, D.A., Shain, C.N. and LaMotte, R.H., Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia, J. Neurophysiol., 66 (1991) 212-227.
2. Burgess, P.R. and Perl, E.R., Myelinated afferent fibres responding specifically to noxious stimulation of the skin, J. Physiol. (London), 190 (1967) 541-562.
3. Cervero, F., Gilbert, R., Hammond, R.G.E. and Tanner, J., Development of secondary hyperalgesia following non-painful thermal stimulation of the skin: a psychophysical study in man, Pain, 54 (1993) 181-189.
4. Cervero, F., Meyer, R.A. and Campbell, J.N., A psychophysical study of secondary hyperalgesia: evidence for increased pain to input from nociceptors, Pain, 58 (1994) 21-28.
5. Collingridge, G.L. and Bliss, T.V.P., NMDA receptors - their role in long term potentiation, Trends Neurosci., 10 (1987) 287-293.
6. Dahl, J.B., Brennum, J., Arendt-Nielsen, L., Jensen, T.S. and Kehlet, H., The effect of pre-versus postinjury infiltration with lidocaine on thermal and mechanical hyperalgesia after heat injury to the skin, Pain, 53 (1993) 43-51.
7. Davis, K.D., Meyer, R.A., Tumquist, J.L., Filloon, T.G., Pappagallo, M. and Campbell, J.N., Cutaneous injection of the capsaicin analogue, NE-21610, produces analgesia to heat but not to mechanical stimuli in man, Pain, 61 (1995) 17-26.
8. Fitzgerald, M. and Lynn, B., The sensitization of high threshold mechanoreceptors with myelinated axons by repeated heating, J. Physiol., 265 (1977) 549-563.
9. Graham, D.T., Goodelf, B.S. and Wolff, H.G., Studies on pain: the relation between cutaneous vasodilation, pain threshold and spontaneous itching and pain, Am. J. Med. Sci., (1957) 420-430.
10. Hardy, J.D., Wolff, H.G, and Goodell, H., Experimental evidence on the nature of cutaneous hyperalgesia, J. Clin. Invest., 29 (1950) 115-140.
11. Jänig, W. and Lisney, J.W., Small diameter myelinated afferents produce vasodilation but not plasma extravasation in rat skin, J. Physiol., 415 (1989) 477-486.
12. Koltzenburg, M., Lundberg, L.E.R. and Torebjörk, H.E., Dynamic and static components of mechanical hyperalgesia in human hairy skin, Pain, 51 (1992) 207-219.
13. LaMotte, R.H., Psychophysical and neurophysiological studies of chemically induced cutaneous pain and itch: the case of the missing nociceptor, Prog. Brain Res., 74 (1988) 331-335.
14. LaMotte, R.H., Shain, C.N., Simone, D.A. and Tsai, E.-F.P., Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms, J. Neurophysiol., 66 (1991) 190-211.
15. LaMotte, R.H., Thalhammer, J.G., Torebjörk, H.E. and Robinson, C.J., Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat, J. Neurosci., 2 (1982) 765-781.
16. Lewis, T., Experiments relating to cutaneous hyperalgesia and its spread through somatic nerves, Clin. Sci., 2 (1936) 373-423.
17. Lisney, S.J.W. and Bharali, L.A.M., The axon reflex: an outdated idea or a valid hypothesis? News Physiol. Sci., 4 (1989) 45-48.
18. Mantyh, P.W., DeMaster, E., Malhotra, A., Ghilardi, J.R., Rogers, S.D., Mantyh, C.R., Liu, H., Basbaum, A.I., Vigna, S.R., Maggio, J.E. and Simone, D.A., Receptor endcytosis and dendrite reshaping in spinal neurons after somatosensory stimulation, Science, 268 (1995) 1629-1632.
19. Meyer, R.A., Campbell, J.N. and Raja, S.N., Peripheral neural mechanisms of nociception. In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain, Churchill Livingstone, London, 1994, pp. 13-44.
20. Meyer, R.A., Walker, R.E. and Mountcastle, V.B., A laser stimulator for the study of cutaneous thermal pain sensation, IEEE Trans. Biomed. Eng., 23 (1976) 54-60.
21. Meyer, R.A., Fuchs, P.N. and Raja, S.N., Intradermal norepinephrine produces a dose dependant hyperalgesia to heat in humans, IASP 8th World Congress on Pain, Abstract (1996) p. 398.
22. Moiniche, S., Dahl, J.B, and Kehlet, H., Time course of primary and secondary hyperalgesia after heat injury to the skin, Br. J. Anaesth., 71 (1993) 201-205.
23. Ochoa, J.L. and Yarnitsky, D., Mechanical hyperalgesias in neuropathic pain patients: dynamic and static subtypes, Ann. Neurol., 33 (1993) 465-472.
24. Perl, E.R., Myelinated afferent fibres innervating the primate skin and their response to noxious stimuli, J. Physiol. (London), 197 (1968) 593-615.
25. Raja, S.N., Campbell, J.N. and Meyer, R.A., Evidence for different mechanisms of primary and secondary hyperalgesia following heat injury to the glabrous skin, Brain, 107 (1984) 1179-1188.
26. Serra, J., Campero, M. and Ochoa, J., 'Secondary' hyperalgesia (capsaicin) mediated by C-nociceptors, Soc. Neurosci. Abstr., 19 (1993) 965.
27. Simone, D.A., Baumann, T.K. and LaMotte, R.H., Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin, Pain, 38 (1989) 99-107.
28. Simone, D.A., Baumann, T.K., Collins, J.K. and LaMotte, R.H., Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicin, Brain Res., 486 (1989b) 185-189.
29. Simone, D.A., Sorkin, L.S., Oh, U., Chung, J.M., Owens, C., LaMotte, R.H. and Willis, W.D., Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons, J. Neurophysiol., 66 (1991) 228-246.
30. Szolcsányi, J., A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain, J. Physiol. (Paris), 73 (1977) 251-259.
31. Szolcsányi, J., Pórszász, R. and Pethö, G., Capsaicin and pharmacology of nociceptors. In: J.M. Besson, G. Guilbaud and H. Ollat (Eds.), Peripheral Neurons in Nociception: Physio-Pharmacolological Aspects, John Libbey Eurotext, Paris, 1994, pp. 109-124.
32. Tal, M. and Bennett G.J., Neuropathic pain sensations are differentially sensitive to dextrophan, NeuroReport, 5 (1994) 1438-1440
33. Torebjörk, H.E., Lundberg, L.E.R. and LaMotte, R.H., Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans, J. Physiol. (London), 448 (1992) 765-780.
34. Treede, R.-D. and Cole, J.D., Dissociated secondary hyperalgesia in a subject with large fibre sensory neuropathy. Pain, 53 (1993) 169-174.
35. Treede, R.D., Meyer, R.A., Raja, S.N. and Campbell, J.N., Evidence for two different heat transduction mechanisms in nociceptive primary afferents innervating monkey skin, J. Physiol. (London), 483.3 (1995) 747-758.
36. Wall, P.D., Neurophysiological mechanisms of referred pain and hyperalgesia. In: L. Vecchiet, D. Albe-Fessard, U. Lindblom and M.A. Giamberardino (Eds.), New Trends in Referred Pain and Hyperalgesia, Elsevier, Amsterdam, 1993, pp. 3-12.
37. Willis, W.D. and Coggeshall, R.E., Sensory Mechanisms of The Spinal Cord, Plenum Press, New York, 1991.