Synthesis and in vitro photodynamic activities of water-soluble fluorinated tetrapyridylporphyrins as tumor photosensitizers

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 10, 2007, Pages 2789-2794

  Ko, Yoon Joo ^a   Yun, Kyung Jin ^b   Kang, Min Seok ^b   Park, Jongmin ^a   Lee, Kyung Tae ^b   Park, Seung Bum ^a   Shin, Jung Hyu ^a  

^a Seoul National University   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

Fluorinated tetrapyridylporphyrins; Photocytotoxicity; Photodynamic therapy (PDT); Photosensitizer; Reactive oxygen species (ROS)

Indexed keywords

5,10,15,20 TETRAKIS(N METHYL 2 FLUOROPYRIDIN 3 YL)PORPHYRIN; CATION; DICHLOROFLUORESCEIN; FLUORINATED TETRAPYRIDYLPORPHYRIN; FLUORINE; PORPHYRIN DERIVATIVE; PYRIDINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BLEACHING; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; DRUG SYNTHESIS; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; FLUOROMETRY; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PHOTODYNAMIC THERAPY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; FLUORINE; HELA CELLS; HUMANS; PHOTOCHEMISTRY; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; SOLUBILITY; WATER;

EID: 34247344532     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.02.083     Document Type: Article

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