-
2
-
-
0344908231
-
Portrait of a killer: The mitochondrial apoptosome emerges from the shadows
-
Hill MM, Adrain C, Martin SJ. Portrait of a killer: The mitochondrial apoptosome emerges from the shadows. Mol Interv 2003; 3:19-26.
-
(2003)
Mol Interv
, vol.3
, pp. 19-26
-
-
Hill, M.M.1
Adrain, C.2
Martin, S.J.3
-
3
-
-
3943071150
-
Cytochrome C-mediated apoptosis
-
Jiang X, Wang X. Cytochrome C-mediated apoptosis. Annu Rev Biochem 2004; 73:87-106.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 87-106
-
-
Jiang, X.1
Wang, X.2
-
5
-
-
1142299539
-
Isolation of p53-target genes and their functional analysis
-
Nakamura Y. Isolation of p53-target genes and their functional analysis. Cancer Sci 2004; 95:7-11.
-
(2004)
Cancer Sci
, vol.95
, pp. 7-11
-
-
Nakamura, Y.1
-
6
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas MS, Alarcon RM, Yoshida H, Giaccia AJ, Hakem R, Mak TW, Lowe SW. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 1999; 284:156-9.
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowe, S.W.7
-
7
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas MS, Capodieci P, Polsky D, Mora J, Esteller M, Opitz-Araya X, McCombie R, Herman JG, Gerald WL, Lazebnik YA, Cordon-Cardo C, Lowe SW. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 2001; 409:207-11.
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
Mora, J.4
Esteller, M.5
Opitz-Araya, X.6
McCombie, R.7
Herman, J.G.8
Gerald, W.L.9
Lazebnik, Y.A.10
Cordon-Cardo, C.11
Lowe, S.W.12
-
8
-
-
0038793948
-
Apoptosis and melanoma chemoresistance
-
Soengas MS, Lowe SW. Apoptosis and melanoma chemoresistance. Oncogene 2003; 22:3138-51.
-
(2003)
Oncogene
, vol.22
, pp. 3138-3151
-
-
Soengas, M.S.1
Lowe, S.W.2
-
9
-
-
10744220426
-
Analysis of APAF-1 expression in human cutaneous melanoma progression
-
Baldi A, Santini D, Russo P, Catricala C, Amantea A, Picardo M, Tatangelo F, Botti G, Dragonetti E, Murace R, Tonini G, Natali PG, Baldi F, Paggi MG. Analysis of APAF-1 expression in human cutaneous melanoma progression. Exp Dermatol 2004; 13:93-7.
-
(2004)
Exp Dermatol
, vol.13
, pp. 93-97
-
-
Baldi, A.1
Santini, D.2
Russo, P.3
Catricala, C.4
Amantea, A.5
Picardo, M.6
Tatangelo, F.7
Botti, G.8
Dragonetti, E.9
Murace, R.10
Tonini, G.11
Natali, P.G.12
Baldi, F.13
Paggi, M.G.14
-
10
-
-
0034674306
-
Transduction of Apaf-1 or caspase-9 induces apoptosis in A-172 cells that are resistant to p53-mediated apoptosis
-
Shinoura N, Sakurai S, Asai A, Kirino T, Hamada H. Transduction of Apaf-1 or caspase-9 induces apoptosis in A-172 cells that are resistant to p53-mediated apoptosis. Biochem Biophys Res Commun 2000; 272:667-73.
-
(2000)
Biochem Biophys Res Commun
, vol.272
, pp. 667-673
-
-
Shinoura, N.1
Sakurai, S.2
Asai, A.3
Kirino, T.4
Hamada, H.5
-
11
-
-
0242667892
-
Frequent LOH at chromosome 12q22-23 and Apaf-1 inactivation in glioblastoma
-
Watanabe T, Hirota Y, Arakawa Y, Fujisawa H, Tachibana O, Hasegawa M, Yamashita J, Hayashi Y. Frequent LOH at chromosome 12q22-23 and Apaf-1 inactivation in glioblastoma. Brain Pathol 2003; 13:431-9.
-
(2003)
Brain Pathol
, vol.13
, pp. 431-439
-
-
Watanabe, T.1
Hirota, Y.2
Arakawa, Y.3
Fujisawa, H.4
Tachibana, O.5
Hasegawa, M.6
Yamashita, J.7
Hayashi, Y.8
-
12
-
-
0034055156
-
Frameshift mutations in Fas, Apaf-1, and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype
-
Yamamoto H, Gil J, Schwartz Jr S, Perucho M. Frameshift mutations in Fas, Apaf-1, and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype. Cell Death Differ 2000; 7:238-9.
-
(2000)
Cell Death Differ
, vol.7
, pp. 238-239
-
-
Yamamoto, H.1
Gil, J.2
Schwartz Jr, S.3
Perucho, M.4
-
13
-
-
0033623874
-
Genetic analysis of the APAF1 gene in male germ cell tumors
-
Bala S, Oliver H, Renault B, Montgomery K, Dutta S, Rao P, Houldsworth J, Kucherlapati R, Wang X, Chaganti RS, Murty VV. Genetic analysis of the APAF1 gene in male germ cell tumors. Genes Chromosomes Cancer 2000; 28:258-68.
-
(2000)
Genes Chromosomes Cancer
, vol.28
, pp. 258-268
-
-
Bala, S.1
Oliver, H.2
Renault, B.3
Montgomery, K.4
Dutta, S.5
Rao, P.6
Houldsworth, J.7
Kucherlapati, R.8
Wang, X.9
Chaganti, R.S.10
Murty, V.V.11
-
14
-
-
33645685206
-
Silencing of APAF-1 in B-CLL results in poor prognosis in the case of concomitant p53 mutation
-
Sturm I, Bosanquet AG, Radetzki S, Hummel M, Dorken B, Daniel PT. Silencing of APAF-1 in B-CLL results in poor prognosis in the case of concomitant p53 mutation. Int J Cancer 2006; 118:2329-36.
-
(2006)
Int J Cancer
, vol.118
, pp. 2329-2336
-
-
Sturm, I.1
Bosanquet, A.G.2
Radetzki, S.3
Hummel, M.4
Dorken, B.5
Daniel, P.T.6
-
15
-
-
0141724605
-
The genetics of pancreatic cancer
-
Cowgill SM, Muscarella P. The genetics of pancreatic cancer. Am J Surg 2003; 186:279-86.
-
(2003)
Am J Surg
, vol.186
, pp. 279-286
-
-
Cowgill, S.M.1
Muscarella, P.2
-
16
-
-
0032818440
-
Molecular genetic basis of pancreatic adenocarcinoma
-
Hilgers W, Kern SE. Molecular genetic basis of pancreatic adenocarcinoma. Genes Chromosomes Cancer 1999; 26:1-12.
-
(1999)
Genes Chromosomes Cancer
, vol.26
, pp. 1-12
-
-
Hilgers, W.1
Kern, S.E.2
-
17
-
-
0028875562
-
Allelotype of pancreatic adenocarcinoma using xenograft enrichment
-
Hahn SA, Seymour AB, Hoque AT, Schutte M, da Costa LT, Redston MS, Caldas C, Weinstein CL, Fischer A, Yeo CJ, et al. Allelotype of pancreatic adenocarcinoma using xenograft enrichment. Cancer Res 1995; 55:4670-5.
-
(1995)
Cancer Res
, vol.55
, pp. 4670-4675
-
-
Hahn, S.A.1
Seymour, A.B.2
Hoque, A.T.3
Schutte, M.4
da Costa, L.T.5
Redston, M.S.6
Caldas, C.7
Weinstein, C.L.8
Fischer, A.9
Yeo, C.J.10
-
18
-
-
0029854322
-
Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: Identification of a I-cM region of common allelic loss
-
Kimura M, Abe T, Sunamura M, Matsuno S, Horii A. Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: Identification of a I-cM region of common allelic loss. Genes Chromosomes Cancer 1996; 17:88-93.
-
(1996)
Genes Chromosomes Cancer
, vol.17
, pp. 88-93
-
-
Kimura, M.1
Abe, T.2
Sunamura, M.3
Matsuno, S.4
Horii, A.5
-
19
-
-
15144342086
-
Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer
-
Kimura M, Furukawa T, Abe T, Yatsuoka T, Youssef EM, Yokoyama T, Ouyang H, Ohnishi Y, Sunamura M, Kobari M, Matsuno S, Horii A. Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer. Cancer Res 1998; 58:2456-60.
-
(1998)
Cancer Res
, vol.58
, pp. 2456-2460
-
-
Kimura, M.1
Furukawa, T.2
Abe, T.3
Yatsuoka, T.4
Youssef, E.M.5
Yokoyama, T.6
Ouyang, H.7
Ohnishi, Y.8
Sunamura, M.9
Kobari, M.10
Matsuno, S.11
Horii, A.12
-
20
-
-
0028225322
-
Allelotype of pancreatic adenocarcinoma
-
Seymour AB, Hruban RH, Redston M, Caldas C, Powell SM, Kinzler KW, Yeo CJ, Kern SE. Allelotype of pancreatic adenocarcinoma. Cancer Res 1994; 54:2761-4.
-
(1994)
Cancer Res
, vol.54
, pp. 2761-2764
-
-
Seymour, A.B.1
Hruban, R.H.2
Redston, M.3
Caldas, C.4
Powell, S.M.5
Kinzler, K.W.6
Yeo, C.J.7
Kern, S.E.8
-
21
-
-
0035252589
-
A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease
-
Wagner M, Greten FR, Weber CK, Koschnick S, Mattfeldt T, Deppert W, Kern H, Adler G, Schmid RM. A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease. Genes Dev 2001; 15:286-93.
-
(2001)
Genes Dev
, vol.15
, pp. 286-293
-
-
Wagner, M.1
Greten, F.R.2
Weber, C.K.3
Koschnick, S.4
Mattfeldt, T.5
Deppert, W.6
Kern, H.7
Adler, G.8
Schmid, R.M.9
-
22
-
-
0035207991
-
Genetic profile of 22 pancreatic carcinoma cell lines: Analysis of K-ras, p53, p16 and DPC4/Smad4
-
Moore PS, Sipos B, Orlandini S, Sorio C, Real FX, Lemoine NR, Gress T, Bassi C, Kloppel G, Kalthoff H, Ungefroren H, Lohr M, Scarpa A. Genetic profile of 22 pancreatic carcinoma cell lines: Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch 2001; 439:798-802.
-
(2001)
Virchows Arch
, vol.439
, pp. 798-802
-
-
Moore, P.S.1
Sipos, B.2
Orlandini, S.3
Sorio, C.4
Real, F.X.5
Lemoine, N.R.6
Gress, T.7
Bassi, C.8
Kloppel, G.9
Kalthoff, H.10
Ungefroren, H.11
Lohr, M.12
Scarpa, A.13
-
23
-
-
0038459055
-
A comprehensive characterization of pancreatic ductal carcinoma cell lines: Towards the establishment of an in vitro research platform
-
Sipos B, Moser S, Kalthoff H, Torok V, Lohr M, Kloppel G. A comprehensive characterization of pancreatic ductal carcinoma cell lines: Towards the establishment of an in vitro research platform. Virchows Arch 2003; 442:444-52.
-
(2003)
Virchows Arch
, vol.442
, pp. 444-452
-
-
Sipos, B.1
Moser, S.2
Kalthoff, H.3
Torok, V.4
Lohr, M.5
Kloppel, G.6
-
24
-
-
20044364053
-
Is Apaf-1 expression frequently abrogated in melanoma?
-
Allen JD, Zhang XD, Scott CL, Boyle GM, Hersey P, Strasser A. Is Apaf-1 expression frequently abrogated in melanoma? Cell Death Differ 2005; 12:680-1.
-
(2005)
Cell Death Differ
, vol.12
, pp. 680-681
-
-
Allen, J.D.1
Zhang, X.D.2
Scott, C.L.3
Boyle, G.M.4
Hersey, P.5
Strasser, A.6
-
25
-
-
20044376750
-
Expression and function of the apoptosis effector Apaf-1 in melanoma
-
Peltenburg LT, de Bruin EC, Meersma D, Smit NP, Schrier PI, Medema JP. Expression and function of the apoptosis effector Apaf-1 in melanoma. Cell Death Differ 2005; 12:678-9.
-
(2005)
Cell Death Differ
, vol.12
, pp. 678-679
-
-
Peltenburg, L.T.1
de Bruin, E.C.2
Meersma, D.3
Smit, N.P.4
Schrier, P.I.5
Medema, J.P.6
-
26
-
-
30844456225
-
Apaf-1 expression in malignant melanoma
-
Soengas MS, Gerald WL, Cordon-Cardo C, Lazebnik Y, Lowe SW. Apaf-1 expression in malignant melanoma. Cell Death Differ 2006; 13:352-3.
-
(2006)
Cell Death Differ
, vol.13
, pp. 352-353
-
-
Soengas, M.S.1
Gerald, W.L.2
Cordon-Cardo, C.3
Lazebnik, Y.4
Lowe, S.W.5
-
27
-
-
0033613143
-
Caspase activation: The induced-proximity model
-
Salvesen GS, Dixit VM. Caspase activation: The induced-proximity model. Proc Natl Acad Sci USA 1999; 96:10964-7.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10964-10967
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
28
-
-
2342453921
-
Death receptors in chemotherapy and cancer
-
Debatin KM, Krammer PH. Death receptors in chemotherapy and cancer. Oncogene 2004; 23:2950-66.
-
(2004)
Oncogene
, vol.23
, pp. 2950-2966
-
-
Debatin, K.M.1
Krammer, P.H.2
-
29
-
-
17444383660
-
Apoptosome dysfunction in human cancer
-
Hajra KM, Liu JR. Apoptosome dysfunction in human cancer. Apoptosis 2004; 9:691-704.
-
(2004)
Apoptosis
, vol.9
, pp. 691-704
-
-
Hajra, K.M.1
Liu, J.R.2
-
30
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone RW, Ruefli AA, Lowe SW. Apoptosis: A link between cancer genetics and chemotherapy. Cell 2002; 108:153-64.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
31
-
-
0346492579
-
Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation
-
Scott CL, Schuler M, Marsden VS, Egle A, Pellegrini M, Nesic D, Gerondakis S, Nutt SL, Green DR, Strasser A. Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation. J Cell Biol 2004; 164:89-96.
-
(2004)
J Cell Biol
, vol.164
, pp. 89-96
-
-
Scott, C.L.1
Schuler, M.2
Marsden, V.S.3
Egle, A.4
Pellegrini, M.5
Nesic, D.6
Gerondakis, S.7
Nutt, S.L.8
Green, D.R.9
Strasser, A.10
-
32
-
-
0037128667
-
Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma
-
Gerhard MC, Schmid RM, Hacker G. Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma. Br J Cancer 2002; 86:893-8.
-
(2002)
Br J Cancer
, vol.86
, pp. 893-898
-
-
Gerhard, M.C.1
Schmid, R.M.2
Hacker, G.3
-
33
-
-
0141725730
-
Mode of action of docetaxel - A basis for combination with novel anticancer agents
-
Herbst RS, Khuri FR. Mode of action of docetaxel - A basis for combination with novel anticancer agents. Cancer Treat Rev 2003; 29:407-15.
-
(2003)
Cancer Treat Rev
, vol.29
, pp. 407-415
-
-
Herbst, R.S.1
Khuri, F.R.2
-
34
-
-
0030973417
-
Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells
-
Faleiro L, Kobayashi R, Fearnhead H, Lazebnik Y. Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. Embo J 1997; 16:2271-81.
-
(1997)
Embo J
, vol.16
, pp. 2271-2281
-
-
Faleiro, L.1
Kobayashi, R.2
Fearnhead, H.3
Lazebnik, Y.4
|