Effects of two conventional preoperative radiation schedules on anastomotic healing in the rat colon

European Surgical Research

Volumn 39, Issue 3, 2007, Pages 141-147

  Bedirli, Abdulkadir ^a,b   Kerem, Mustafa ^a   Karahacioglu, Eray ^a   Ofluoglu, Ebru ^a   Yilmaz, T Utku ^a   Pasaoglu, Hatice ^a   Tater, O Petek ^a   Sakrak, Omer ^a   Pak, Yucel ^a  

^a GAZI UNIVERSITY FACULTY OF MEDICINE   (Turkey)

^b NONE   (Turkey)

Author keywords

Anastomosis; Colon; Healing; Matrix metalloproteinases; Preoperative irradiation

Indexed keywords

GELATINASE A; GELATINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON; COLON ANASTOMOSIS; CONTROLLED STUDY; MALE; NONHUMAN; PERITONITIS; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RAT; RECTUM CANCER; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME; WISTAR RAT; WOUND HEALING;

ANASTOMOSIS, SURGICAL; ANIMALS; BIOMECHANICS; COLON; HYDROXYPROLINE; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PREOPERATIVE CARE; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RATS; RATS, WISTAR; RECTAL NEOPLASMS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; WOUND HEALING;

EID: 34247342177     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000100111     Document Type: Article

References (34)

1. Abulafi AM: Local recurrence of colorectal cancer: the problem, mechanisms, management and adjuvant therapy. Br J Surg 1994;81:7-19.
2. MacFarlane JK, Ryall RD, Heald RJ: Mesorectal excision for rectal cancer. Lancet 1993;341:457-460.
3. Pahlman L, Glimelius B: Pre- or postoperative radiotherapy in rectal and rectosigmoid carcinoma: report from a randomized multicenter trial. Ann Surg 1990;211:187-195.
4. Swedish Rectal Cancer Trial: Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med 1997;336:980-987.
5. Parks WC: Matrix metalloproteinases in repair. Wound Repair Regen 1999;7:423-432.
6. Shaper KR, Savage FJ, Hembry RM, Boulos PB: Regulation of matrix metalloproteinases in a model of colonic wound healing in a rabbit. Dis Colon Rectum 2001;44:1857-1866.
7. De Hingh IH, de Man BM, Lomme RM, van Goor H, Hendriks T: Colonic anastomotic strength and matrix metalloproteinase activity in an experimental model of bacterial peritonitis. Br J Surg 2003;90:981-988.
8. Kerem M, Bedirli A, Karahacioglu E, Pasaoglu H, Sahin O, Bayraktar N, et al: Effects of soluble fiber on matrix metalloproteinase-2 activity and healing of colon anastomosis in rats given radiotherapy. Clin Nutr 2006;25:661-670.
9. Chowcat NL, Savage FJ, Lewin MR, Boulos PB: Direct measurement of collagenase in colonic anastomosis. Br J Surg 1990;77: 1284-1287.
10. Stumpf M: Changes of the extracellular matrix as a risk factor for anastomotic leakage after large bowel surgery. Surgery 2005;137: 229-234.
11. Savage FJ, Lacombe DL, Boulos PB, Hembry RM: Role of matrix metalloproteinases in healing of colonic anastomosis. Dis Colon Rectum 1997;40:962-970.
12. De Waard JW, Wobbes T, de Man BM, van der Linden CJ, Hendriks T: Post-operative levamisole may compromise early healing of experimental intestinal anastomoses. Br J Cancer 1995;72:456-460.
13. Jamall IS, Finelli VN, Que Hee SS: A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues. Anal Biochem 1981;112:70-75.
14. Camma C, Giunta M, Fiorica F, Pagliaro L, Craxi A, Cottone M: Preoperative radiotherapy for resectable rectal cancer: a meta-analysis. JAMA 2000;284:1008-1015.
15. Kapiteijn E, Marijnen CA, Nagtegaal ID, Putter H, Steup WH, Wiggers T, et al: Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 2001;345:638-646.
16. Marijnen CA, Kapiteijn E, van de Velde CJ, Martijn H, Steup WH, Wiggers T, et al: Acute side effects and complications after shortterm preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter randomized trial. J Clin Oncol 2002;20:817-825.
17. Johnson LB, Jorgensen LN, Adawi D, Blomqvist P, Asklof GB, Gottrup F, et al: The effect of preoperative radiotherapy on systemic collagen deposition and postoperative infective complications in rectal cancer patients. Dis Colon Rectum 2005;48:1573-1580.
18. Alberts JC, Parvaiz A, Moran BJ: Predicting risk and diminishing the consequences of anastomotic dehiscence following rectal resection. Colorectal Dis 2003;5:478-482.
19. Biert J, Hoogenhout J, Wobbes T, Hendriks T: High-dose preoperative irradiation without detrimental effect on early repair of anastomoses in the colon of the rat. Radiat Res 1997;147:362-368.
20. Terzi C, Sevinc AI, Kocdor H, Oktay G, Alanyali H, Kupelioglu A, et al: Improvement of colonic healing by preoperative rectal irrigation with short-chain fatty acids in rats given radiotherapy. Dis Colon Rectum 2004; 47:2184-2194.
21. El-Malt M, Ceelen W, De Meerleer G, Verstraete A, Boterberg T, Van Belle S, et al: Influence of preoperative combined radiochemotherapy on surgical outcome and colonic anastomotic healing: experimental study in the rat. Int J Radiat Oncol Biol Phys 2001;50: 1073-1078.
22. Witte MB, Barbul A: General principles of wound healing. Surg Clin North Am 1997;77:509-528.
23. Jonsson K, Jiborn H, Zederfeldt B: Breaking strength of small intestinal anastomoses. Am J Surg 1983;145:800-803.
24. Seifert WF, Wobbes T, Hendriks T: Divergent patterns of matrix metalloproteinase activity during wound healing in ileum and colon of rats. Gut 1996;39:114-119.
25. Vaalamo M, Karjalainen-Lindsberg ML, Puolakkainen P, Kere J, Saarialho-Kere U: Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulceration. Am J Pathol 1998;152:1005-1014.
26. Seifert WF, Wobbes T, Hoogenhout J, de Man BM, Hendriks T: Intra-operative irradiation prolongs the presence of matrix metalloproteinase activity in large bowel anastomoses of the rat. Radiat Res 1997;147:354-361.
27. Kumar A, Collins HM, Scholefield JH, Watson SA: Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer. Br J Cancer 2002;82:960-965.
28. Nostrant T, Robertson J, Lawrence T: Radiation injury;in Yamada T (eds): Textbook of Gastroenterology. Philadelphia, Lippincott, 1995, pp 2524-2535.
29. Schultze-Mosgau S, Wehrhan F, Rodel F, Aman K, Radespiel-Troger M, Grabenbauer GG: Transforming growth factor-beta receptor-II up-regulation during wound healing in previously irradiated graft beds in vivo. Wound Repair Regen 2003;11:297-305.
30. Graf W, Dahlberg M, Osman MM, Holmberg L, Pahlman L, Glimelius B: Short-term preoperative radiotherapy results in downstaging of rectal cancer: a study of 1316 patients. Radiother Oncol 1997;43:133-137.
31. Kaminsky-Forrett MC, Conroy T, Luporsi E, Peiffert D, Lapeyre M, Boissel P, et al: Prognostic implications of downstaging following preoperative radiation therapy for operable T3-T4 rectal cancer. Int J Radiat Oncol Biol Phys 1998;42:935-941.
32. Francois Y, Nemoz CJ, Baulieux J, Vignal J, Grandjean JP, Partensky C, et al: Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90-01 randomized trial. J Clin Oncol 1999;17:2396-2402.
33. Suwinski R, Taylor JM, Withers HR: Rapid growth of microscopic rectal cancer as a determinant of response to preoperative radiation therapy. Int J Radiat Oncol Biol Phys 1998;42:943-951.
34. Fowler JF: Potential for increasing the differential response between tumors and normal tissues: can proliferation rate be used? Int J Radiat Oncol Biol Phys 1986;12:641-645.