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Volumn 64, Issue 5, 2007, Pages 377-389

Analysis of the weak interactions of ADP-Unc104 and ADP-kinesin with microtubules and their inhibition by MAP2c

Author keywords

Kinesin; MAP2c; Microtubule; Unc104

Indexed keywords

ADENOSINE DIPHOSPHATE; KINESIN; KINESIN 1; KINESIN 3; MICROTUBULE ASSOCIATED PROTEIN; MUTANT PROTEIN; PROTEIN MAP2; PROTEIN MAP2C; PROTEIN UNC104; TUBULIN; UNCLASSIFIED DRUG;

EID: 34247277247     PISSN: 08861544     EISSN: 10970169     Source Type: Journal    
DOI: 10.1002/cm.20190     Document Type: Article
Times cited : (9)

References (47)
  • 1
    • 0037166943 scopus 로고    scopus 로고
    • MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
    • Al-Bassam J, Ozer RS, Safer D, Halpain S, Milligan RA. 2002. MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments. J Cell Biol 157:1187-1184.
    • (2002) J Cell Biol , vol.157 , pp. 1187-1184
    • Al-Bassam, J.1    Ozer, R.S.2    Safer, D.3    Halpain, S.4    Milligan, R.A.5
  • 3
    • 0037451130 scopus 로고    scopus 로고
    • Axonal transport of membranous and nonmembranous cargoes: A unified perspective
    • Brown A. 2003. Axonal transport of membranous and nonmembranous cargoes: a unified perspective. J Cell Biol 160:817-814.
    • (2003) J Cell Biol , vol.160 , pp. 817-814
    • Brown, A.1
  • 4
    • 0028117919 scopus 로고
    • Purification and characterization of ensconsin, a novel microtubule stabilizing protein
    • Bulinski JC, Bossier A. 1994. Purification and characterization of ensconsin, a novel microtubule stabilizing protein. J Cell Sci 107:2839-2844.
    • (1994) J Cell Sci , vol.107 , pp. 2839-2844
    • Bulinski, J.C.1    Bossier, A.2
  • 5
    • 0031469160 scopus 로고    scopus 로고
    • Overexpression of MAP4 inhibits organelle motility and trafficking in vivo
    • Bulinski JC, McGraw TE, Gruber D, Nguyen HL, Sheetz MP. 1997. Overexpression of MAP4 inhibits organelle motility and trafficking in vivo. J Cell Sci 110:3055-3064.
    • (1997) J Cell Sci , vol.110 , pp. 3055-3064
    • Bulinski, J.C.1    McGraw, T.E.2    Gruber, D.3    Nguyen, H.L.4    Sheetz, M.P.5
  • 6
    • 0034826896 scopus 로고    scopus 로고
    • Regulation of microtubule-associated proteins
    • Cassimeris L, Spittle C. 2001. Regulation of microtubule-associated proteins. Int Rev Cytol 210:163-226.
    • (2001) Int Rev Cytol , vol.210 , pp. 163-226
    • Cassimeris, L.1    Spittle, C.2
  • 7
    • 0028816841 scopus 로고
    • Non-cooperative binding of the MAP-2 microtubule-binding region to microtubules
    • Coffey RL, Purich DL. 1995. Non-cooperative binding of the MAP-2 microtubule-binding region to microtubules. J Biol Chem 270:1035-1044.
    • (1995) J Biol Chem , vol.270 , pp. 1035-1044
    • Coffey, R.L.1    Purich, D.L.2
  • 8
    • 0346750747 scopus 로고    scopus 로고
    • Actin and microtubules in neurite initiation: Are MAPs the missing link?
    • Dehmelt L, Halpain S. 2004. Actin and microtubules in neurite initiation: are MAPs the missing link? J Neurobiol 58:18-33.
    • (2004) J Neurobiol , vol.58 , pp. 18-33
    • Dehmelt, L.1    Halpain, S.2
  • 9
    • 19744382953 scopus 로고    scopus 로고
    • The MAP2/Tau family of microtubule-associated proteins
    • Dehmelt L, Halpain S. 2005. The MAP2/Tau family of microtubule-associated proteins. Genome Biol 6:204.
    • (2005) Genome Biol , vol.6 , pp. 204
    • Dehmelt, L.1    Halpain, S.2
  • 11
    • 0032476645 scopus 로고    scopus 로고
    • Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease
    • Ebneth A, Godemann R, Stamer K, Illenberger S, Trinczek B, Mandelkow E. 1998. Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease. J Cell Biol 143:777-794.
    • (1998) J Cell Biol , vol.143 , pp. 777-794
    • Ebneth, A.1    Godemann, R.2    Stamer, K.3    Illenberger, S.4    Trinczek, B.5    Mandelkow, E.6
  • 12
    • 0029842118 scopus 로고    scopus 로고
    • Recombinant microtubule-associated protein 2c reduces the dynamic instability of individual microtubules
    • Gamblin TC, Nachmanoff K, Halpain S, Williams RC, Jr. 1996. Recombinant microtubule-associated protein 2c reduces the dynamic instability of individual microtubules. Biochemistry 35:12576-12584.
    • (1996) Biochemistry , vol.35 , pp. 12576-12584
    • Gamblin, T.C.1    Nachmanoff, K.2    Halpain, S.3    Williams Jr., R.C.4
  • 13
    • 0035575469 scopus 로고    scopus 로고
    • Molecular motors: From one motor many tails to one motor many tales
    • Goldstein LS. 2001. Molecular motors: from one motor many tails to one motor many tales. Trends Cell Biol 11:477-484.
    • (2001) Trends Cell Biol , vol.11 , pp. 477-484
    • Goldstein, L.S.1
  • 14
    • 0347381071 scopus 로고    scopus 로고
    • Gordon-Weeks PR. Microtubules and growth cone function. 2004. J Neurobiol 58:70-74.
    • Gordon-Weeks PR. Microtubules and growth cone function. 2004. J Neurobiol 58:70-74.
  • 15
    • 0025844789 scopus 로고
    • Kinesin-related gene Unc-104 is required for axonal transport of synaptic vesicles in C. elegans
    • Hall DH, Hedgecock EM. 1991. Kinesin-related gene Unc-104 is required for axonal transport of synaptic vesicles in C. elegans. Cell 65:837-844.
    • (1991) Cell , vol.65 , pp. 837-844
    • Hall, D.H.1    Hedgecock, E.M.2
  • 16
    • 14844331501 scopus 로고    scopus 로고
    • Molecular motors and mechanisms of directional transport in neurons
    • Hirokawa N, Takemura R. 2005. Molecular motors and mechanisms of directional transport in neurons. Nat Rev Neurosci 6:201-204.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 201-204
    • Hirokawa, N.1    Takemura, R.2
  • 17
    • 0032550175 scopus 로고    scopus 로고
    • Image reconstructions of microtubules decorated with monomeric and dimeric kinesins: Comparison with x-ray structure and implications for motility
    • Hoenger A, Sack S, Thormahlen M, Marx A, Muller J, Gross H, Mandelkow E. 1998. Image reconstructions of microtubules decorated with monomeric and dimeric kinesins: comparison with x-ray structure and implications for motility. J Cell Biol 141:419-424.
    • (1998) J Cell Biol , vol.141 , pp. 419-424
    • Hoenger, A.1    Sack, S.2    Thormahlen, M.3    Marx, A.4    Muller, J.5    Gross, H.6    Mandelkow, E.7
  • 18
    • 0029965781 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics
    • Illenberger S, Drewes G, Trinczek B, Biernat J, Meyer HE, Olmsted JB, Mandelkow EM, Mandelkow E. 1996. Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics. J Biol Chem 271:834-844.
    • (1996) J Biol Chem , vol.271 , pp. 834-844
    • Illenberger, S.1    Drewes, G.2    Trinczek, B.3    Biernat, J.4    Meyer, H.E.5    Olmsted, J.B.6    Mandelkow, E.M.7    Mandelkow, E.8
  • 19
    • 0034695259 scopus 로고    scopus 로고
    • 15 A resolution model of the monomeric kinesin motor, KIF1A
    • Kikkawa M, Okada Y, Hirokawa N. 2000. 15 A resolution model of the monomeric kinesin motor, KIF1A. Cell 100:241-252.
    • (2000) Cell , vol.100 , pp. 241-252
    • Kikkawa, M.1    Okada, Y.2    Hirokawa, N.3
  • 21
    • 0027285334 scopus 로고
    • Microtubule-associated protein 2 alters the dynamic properties of microtubule assembly and disassembly
    • Kowalski RJ, Williams RC, Jr. 1993. Microtubule-associated protein 2 alters the dynamic properties of microtubule assembly and disassembly. J Biol Chem 268:9847-9855.
    • (1993) J Biol Chem , vol.268 , pp. 9847-9855
    • Kowalski, R.J.1    Williams Jr., R.C.2
  • 22
    • 0027533201 scopus 로고
    • Steric inhibition of cytoplasmic dynein and kinesin motility by MAP2
    • Lopez LA, Sheetz MP. 1993. Steric inhibition of cytoplasmic dynein and kinesin motility by MAP2. Cell Motil Cytoskeleton 24:1-4.
    • (1993) Cell Motil Cytoskeleton , vol.24 , pp. 1-4
    • Lopez, L.A.1    Sheetz, M.P.2
  • 23
    • 5444273804 scopus 로고    scopus 로고
    • MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons
    • Mandelkow EM, Thies E, Trinczek B, Biernat J, Mandelkow E. 2004. MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons. J Cell Biol 167:99-94.
    • (2004) J Cell Biol , vol.167 , pp. 99-94
    • Mandelkow, E.M.1    Thies, E.2    Trinczek, B.3    Biernat, J.4    Mandelkow, E.5
  • 24
    • 0021686169 scopus 로고
    • Dynamic instability of microtubule growth
    • Mitchison T, Kirschner M. 1984. Dynamic instability of microtubule growth. Nature 312:237-242.
    • (1984) Nature , vol.312 , pp. 237-242
    • Mitchison, T.1    Kirschner, M.2
  • 25
    • 0028641560 scopus 로고    scopus 로고
    • Nangaku M, Sato-Yoshitake R, Okada Y, Noda R, Takemura , Yamazaki H, Hirokawa N. 1994. KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell 79:1209-1214.
    • Nangaku M, Sato-Yoshitake R, Okada Y, Noda R, Takemura , Yamazaki H, Hirokawa N. 1994. KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell 79:1209-1214.
  • 26
    • 0033786279 scopus 로고    scopus 로고
    • Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton
    • Ozer RS, Halpain S. 2000. Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton. Mol Biol Cell 11:3573-3574.
    • (2000) Mol Biol Cell , vol.11 , pp. 3573-3574
    • Ozer, R.S.1    Halpain, S.2
  • 27
    • 0034681137 scopus 로고    scopus 로고
    • Mechanism of the single-headed processivity: Diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin
    • Okada Y, Hirokawa N. 2000. Mechanism of the single-headed processivity: diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin. Proc Natl Acad Sci 97:640-644.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 640-644
    • Okada, Y.1    Hirokawa, N.2
  • 28
    • 0031615152 scopus 로고    scopus 로고
    • Assaying processive movement of kinesin by fluorescence microscopy
    • Pierce DW, Vale RD. 1998. Assaying processive movement of kinesin by fluorescence microscopy. Methods Enzymol 298:154-164.
    • (1998) Methods Enzymol , vol.298 , pp. 154-164
    • Pierce, D.W.1    Vale, R.D.2
  • 29
    • 0033608963 scopus 로고    scopus 로고
    • Single-molecule behavior of monomeric and heteromeric kinesins
    • Pierce DW, Hom-Booher N, Otsuka AJ, Vale RD. 1999. Single-molecule behavior of monomeric and heteromeric kinesins. Biochemistry 38:5412-5414.
    • (1999) Biochemistry , vol.38 , pp. 5412-5414
    • Pierce, D.W.1    Hom-Booher, N.2    Otsuka, A.J.3    Vale, R.D.4
  • 31
    • 1842432582 scopus 로고    scopus 로고
    • MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain
    • Roger B, Al-Bassam J, Dehmelt L, Milligan RA, Halpain S. 2004. MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain. Curr Biol 14:363-364.
    • (2004) Curr Biol , vol.14 , pp. 363-364
    • Roger, B.1    Al-Bassam, J.2    Dehmelt, L.3    Milligan, R.A.4    Halpain, S.5
  • 32
    • 0035903699 scopus 로고    scopus 로고
    • KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry
    • Rogers KR, Weiss S, Crevel I, Brophy PJ, Geeves M, Cross R. 2001. KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry. EMBO J 20:5101-5113.
    • (2001) EMBO J , vol.20 , pp. 5101-5113
    • Rogers, K.R.1    Weiss, S.2    Crevel, I.3    Brophy, P.J.4    Geeves, M.5    Cross, R.6
  • 33
    • 0032559824 scopus 로고    scopus 로고
    • Role of the kinesin neck region in processive microtubule-based motility
    • Romberg L, Pierce DW, Vale RD. 1998. Role of the kinesin neck region in processive microtubule-based motility. J Cell Biol 140:1407-1416.
    • (1998) J Cell Biol , vol.140 , pp. 1407-1416
    • Romberg, L.1    Pierce, D.W.2    Vale, R.D.3
  • 34
    • 46249125930 scopus 로고
    • Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady State Enyzme Systems
    • Segel IH. 1993. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady State Enyzme Systems. New York: Wiley. pp 18-159.
    • (1993) New York: Wiley , pp. 18-159
    • Segel, I.H.1
  • 35
    • 0037119947 scopus 로고    scopus 로고
    • Single-molecule investigation of the interference between kinesin, tau and MAP2c
    • Seitz A, Kojima H, Oiwa K, Mandelkow EM, Song YH, Mandelkow E. 2002. Single-molecule investigation of the interference between kinesin, tau and MAP2c. EMBO J 21:4896-4894.
    • (2002) EMBO J , vol.21 , pp. 4896-4894
    • Seitz, A.1    Kojima, H.2    Oiwa, K.3    Mandelkow, E.M.4    Song, Y.H.5    Mandelkow, E.6
  • 36
    • 0021135071 scopus 로고
    • Controlled proteolysis of tubulin by subtilisin: Localization of the site for MAP2 interaction
    • Serrano L, Avila J, Maccioni RB. 1984. Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interaction. Biochemistry 23:4675-4684.
    • (1984) Biochemistry , vol.23 , pp. 4675-4684
    • Serrano, L.1    Avila, J.2    Maccioni, R.B.3
  • 40
    • 0037128935 scopus 로고    scopus 로고
    • Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
    • Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow EM. 2002. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol 156:1051-1063.
    • (2002) J Cell Biol , vol.156 , pp. 1051-1063
    • Stamer, K.1    Vogel, R.2    Thies, E.3    Mandelkow, E.4    Mandelkow, E.M.5
  • 41
    • 0034722373 scopus 로고    scopus 로고
    • Engineering the processive run length of the kinesin motor
    • Thorn KS, Ubersax JA, Vale RD. 2000. Engineering the processive run length of the kinesin motor. J Cell Biol 151:1093-1094.
    • (2000) J Cell Biol , vol.151 , pp. 1093-1094
    • Thorn, K.S.1    Ubersax, J.A.2    Vale, R.D.3
  • 42
    • 0034722388 scopus 로고    scopus 로고
    • Controlling kinesin by reversible disulfide cross-linking. Identifying the motility-producing conformational change
    • Tomishige M, Vale RD. 2000. Controlling kinesin by reversible disulfide cross-linking. Identifying the motility-producing conformational change. J Cell Biol 151:1081-1092.
    • (2000) J Cell Biol , vol.151 , pp. 1081-1092
    • Tomishige, M.1    Vale, R.D.2
  • 43
    • 0037183926 scopus 로고    scopus 로고
    • Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization
    • Tomishige M, Klopfenstein DR, Vale RD. 2002. Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization. Science 297:2263-2264.
    • (2002) Science , vol.297 , pp. 2263-2264
    • Tomishige, M.1    Klopfenstein, D.R.2    Vale, R.D.3
  • 44
    • 0032799381 scopus 로고    scopus 로고
    • Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles
    • Trinczek B, Ebneth A, Mandelkow EM, Mandelkow E. 1999. Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles. J Cell Sci 112:2355-2364.
    • (1999) J Cell Sci , vol.112 , pp. 2355-2364
    • Trinczek, B.1    Ebneth, A.2    Mandelkow, E.M.3    Mandelkow, E.4
  • 46
    • 0343415156 scopus 로고    scopus 로고
    • The way things move: Looking under the hood of molecular motor proteins
    • Vale RD, Milligan RA. 2000. The way things move: Looking under the hood of molecular motor proteins. Science 288:88-94.
    • (2000) Science , vol.288 , pp. 88-94
    • Vale, R.D.1    Milligan, R.A.2
  • 47
    • 0035371235 scopus 로고    scopus 로고
    • Direct visualization of the movement of the monomeric axonal transport motor UNC-104 along neuronal processes in living Caenorhabditis elegans
    • Zhou HM, Brust-Mascher I, Scholey JM. 2001. Direct visualization of the movement of the monomeric axonal transport motor UNC-104 along neuronal processes in living Caenorhabditis elegans. J Neurosci 21:3749-3754.
    • (2001) J Neurosci , vol.21 , pp. 3749-3754
    • Zhou, H.M.1    Brust-Mascher, I.2    Scholey, J.M.3


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